-
1
-
-
58149380742
-
Stem cell concepts renew cancer research
-
Dick J.E. Stem cell concepts renew cancer research. Blood 2008, 112:4793-4807.
-
(2008)
Blood
, vol.112
, pp. 4793-4807
-
-
Dick, J.E.1
-
2
-
-
79952370202
-
The cancer stem cell: premises, promises and challenges
-
Clevers H. The cancer stem cell: premises, promises and challenges. Nat Med 2011, 313-319.
-
(2011)
Nat Med
, pp. 313-319
-
-
Clevers, H.1
-
3
-
-
44349166602
-
PML targeting eradicates quiescent leukaemia-initiating cells
-
Ito K., Bernardi R., Morotti A., et al. PML targeting eradicates quiescent leukaemia-initiating cells. Nature 2008, 453:1072-1078.
-
(2008)
Nature
, vol.453
, pp. 1072-1078
-
-
Ito, K.1
Bernardi, R.2
Morotti, A.3
-
4
-
-
7744220635
-
MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer
-
Shachaf C.M., Kopelman A.M., Arvanitis C., et al. MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer. Nature 2004, 431:1112-1117.
-
(2004)
Nature
, vol.431
, pp. 1112-1117
-
-
Shachaf, C.M.1
Kopelman, A.M.2
Arvanitis, C.3
-
5
-
-
33750370444
-
MicroRNA signatures in human cancers
-
Calin G.A., Croce C.M. MicroRNA signatures in human cancers. Nat Rev Cancer 2006, 6:857-866.
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 857-866
-
-
Calin, G.A.1
Croce, C.M.2
-
6
-
-
84865589321
-
How does Lin28 let-7 control development and disease?
-
Thornton J.E., Gregory R.I. How does Lin28 let-7 control development and disease?. Trends Cell Biol 2012, 22:474-482.
-
(2012)
Trends Cell Biol
, vol.22
, pp. 474-482
-
-
Thornton, J.E.1
Gregory, R.I.2
-
7
-
-
84876215842
-
Construction of let-7a expression plasmid and its inhibitory effect on k-Ras protein in A549 lung cancer cells
-
He X.Y., Chen J.X., Ou-Yang X., Zhang Z., Peng H.M. Construction of let-7a expression plasmid and its inhibitory effect on k-Ras protein in A549 lung cancer cells. Nan Fang Yi Ke Da Xue Xue Bao 2010, 30:2427-2431.
-
(2010)
Nan Fang Yi Ke Da Xue Xue Bao
, vol.30
, pp. 2427-2431
-
-
He, X.Y.1
Chen, J.X.2
Ou-Yang, X.3
Zhang, Z.4
Peng, H.M.5
-
8
-
-
84876272195
-
Let-7: A regulator of the ERalpha signaling pathway in human breast tumors and breast cancer stem cells
-
Sun X., Qin S., Fan C., Xu C., Du N., Ren H. Let-7: A regulator of the ERalpha signaling pathway in human breast tumors and breast cancer stem cells. Oncol Rep 2013, 29:2079-2087.
-
(2013)
Oncol Rep
, vol.29
, pp. 2079-2087
-
-
Sun, X.1
Qin, S.2
Fan, C.3
Xu, C.4
Du, N.5
Ren, H.6
-
9
-
-
50549095181
-
Let-7 microRNAs in development, stem cells and cancer
-
Büssing I., Slack F.J., Großhans H. Let-7 microRNAs in development, stem cells and cancer. Trends Mol Med 2008, 14:400-409.
-
(2008)
Trends Mol Med
, vol.14
, pp. 400-409
-
-
Büssing, I.1
Slack, F.J.2
Großhans, H.3
-
10
-
-
34548012848
-
The let-7 MicroRNA represses cell proliferation pathways in human cells
-
Johnson C.D., Esquela-Kerscher A., Stefani G., et al. The let-7 MicroRNA represses cell proliferation pathways in human cells. Cancer Res 2007, 67:7713-7722.
-
(2007)
Cancer Res
, vol.67
, pp. 7713-7722
-
-
Johnson, C.D.1
Esquela-Kerscher, A.2
Stefani, G.3
-
11
-
-
72949111146
-
MicroRNA regulation of cancer stem cells and therapeutic implications
-
DeSano J., Xu L. MicroRNA regulation of cancer stem cells and therapeutic implications. AAPS J 2009, 11:682-692.
-
(2009)
AAPS J
, vol.11
, pp. 682-692
-
-
DeSano, J.1
Xu, L.2
-
12
-
-
84872014080
-
Role of let-7 in maintaining characteristics of breast cancer stem cells
-
Sun X., Fan C., Hu L.J., Du N., Xu C.W., Ren H. Role of let-7 in maintaining characteristics of breast cancer stem cells. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2012, 28:789-792.
-
(2012)
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi
, vol.28
, pp. 789-792
-
-
Sun, X.1
Fan, C.2
Hu, L.J.3
Du, N.4
Xu, C.W.5
Ren, H.6
-
13
-
-
38849209304
-
Not miR-ly small RNAs: big potential for micrornas in therapy
-
Love T.M., Moffett H.F., Novina C.D. Not miR-ly small RNAs: big potential for micrornas in therapy. J Allergy Clin Immunol 2008, 121:309-319.
-
(2008)
J Allergy Clin Immunol
, vol.121
, pp. 309-319
-
-
Love, T.M.1
Moffett, H.F.2
Novina, C.D.3
-
14
-
-
81155124248
-
Potential applications of MicroRNAs in cancer diagnosis, prognosis, and treatment
-
Sandhu S., Garzon R. Potential applications of MicroRNAs in cancer diagnosis, prognosis, and treatment. Semin oncol 2011, 38:781-787.
-
(2011)
Semin oncol
, vol.38
, pp. 781-787
-
-
Sandhu, S.1
Garzon, R.2
-
15
-
-
34247495591
-
MiR-21-mediated tumor growth
-
Si M.L., Zhu S., Wu H., Lu Z., Wu F., Mo Y.Y. MiR-21-mediated tumor growth. Oncogene 2007, 26:2799-2803.
-
(2007)
Oncogene
, vol.26
, pp. 2799-2803
-
-
Si, M.L.1
Zhu, S.2
Wu, H.3
Lu, Z.4
Wu, F.5
Mo, Y.Y.6
-
16
-
-
41649114199
-
Suppression of non-small cell lung tumor development by the let-7 microRNA family
-
Kumar M.S., Erkeland S.J., Pester R.E., et al. Suppression of non-small cell lung tumor development by the let-7 microRNA family. Proc Natl Acad Sci USA 2008, 105:3903-3908.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 3903-3908
-
-
Kumar, M.S.1
Erkeland, S.J.2
Pester, R.E.3
-
17
-
-
84863577404
-
Distinct microRNA expression profiles in prostate cancer stem/progenitor cells and tumor-suppressive functions of let-7
-
Liu C., Kelnar K., Vlassov A.V., Brown D., Wang J., Tang D.G. Distinct microRNA expression profiles in prostate cancer stem/progenitor cells and tumor-suppressive functions of let-7. Cancer Res 2012, 72:3393-3404.
-
(2012)
Cancer Res
, vol.72
, pp. 3393-3404
-
-
Liu, C.1
Kelnar, K.2
Vlassov, A.V.3
Brown, D.4
Wang, J.5
Tang, D.G.6
-
18
-
-
77949658280
-
Regression of murine lung tumors by the let-7 microRNA
-
Trang P., Medina P.P., Wiggins J.F., et al. Regression of murine lung tumors by the let-7 microRNA. Oncogene 2010, 29:1580-1587.
-
(2010)
Oncogene
, vol.29
, pp. 1580-1587
-
-
Trang, P.1
Medina, P.P.2
Wiggins, J.F.3
-
19
-
-
34249819336
-
MicroRNA-mediated feedback and feedforward loops are recurrent network motifs in mammals
-
Tsang J., Zhu J., van Oudenaarden A. MicroRNA-mediated feedback and feedforward loops are recurrent network motifs in mammals. Mol Cell 2007, 26:753-767.
-
(2007)
Mol Cell
, vol.26
, pp. 753-767
-
-
Tsang, J.1
Zhu, J.2
van Oudenaarden, A.3
-
20
-
-
80053436022
-
Germline genetic variants disturbing the Let-7/LIN28 double-negative feedback loop alter breast cancer susceptibility
-
Chen A.X., Yu K.D., Fan L., et al. Germline genetic variants disturbing the Let-7/LIN28 double-negative feedback loop alter breast cancer susceptibility. PLoS Genet 2011, 7:e1002259.
-
(2011)
PLoS Genet
, vol.7
-
-
Chen, A.X.1
Yu, K.D.2
Fan, L.3
-
21
-
-
48649103982
-
A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment
-
Rybak A., Fuchs H., Smirnova L., et al. A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment. Nat Cell Biol 2008, 10:987-993.
-
(2008)
Nat Cell Biol
, vol.10
, pp. 987-993
-
-
Rybak, A.1
Fuchs, H.2
Smirnova, L.3
-
22
-
-
84862905774
-
LIN28: A regulator of tumor-suppressing activity of let-7 microRNA in human breast cancer
-
Sakurai M., Miki Y., Masuda M., et al. LIN28: A regulator of tumor-suppressing activity of let-7 microRNA in human breast cancer. J Steroid Biochem Mol Biol 2012, 131:101-106.
-
(2012)
J Steroid Biochem Mol Biol
, vol.131
, pp. 101-106
-
-
Sakurai, M.1
Miki, Y.2
Masuda, M.3
-
23
-
-
47949100595
-
Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing
-
Newman M.A., Thomson J.M., Hammond S.M. Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing. RNA 2008, 14:1539-1549.
-
(2008)
RNA
, vol.14
, pp. 1539-1549
-
-
Newman, M.A.1
Thomson, J.M.2
Hammond, S.M.3
-
24
-
-
81855183636
-
Lin28A and Lin28B Inhibit let-7 MicroRNA biogenesis by distinct mechanisms
-
Piskounova E., Polytarchou C., Thornton James E., et al. Lin28A and Lin28B Inhibit let-7 MicroRNA biogenesis by distinct mechanisms. Cell 2011, 147:1066-1079.
-
(2011)
Cell
, vol.147
, pp. 1066-1079
-
-
Piskounova, E.1
Polytarchou, C.2
Thornton, J.E.3
-
25
-
-
79952847666
-
Myc function in drosophila
-
Bellosta P., Gallant P. Myc function in drosophila. Genes Cancer 2010, 1:542-546.
-
(2010)
Genes Cancer
, vol.1
, pp. 542-546
-
-
Bellosta, P.1
Gallant, P.2
-
26
-
-
20444479428
-
C-Myc-regulated microRNAs modulate E2F1 expression
-
O'Donnell K.A., Wentzel E.A., Zeller K.I., Dang C.V., Mendell J.T. C-Myc-regulated microRNAs modulate E2F1 expression. Nature 2005, 435:839-843.
-
(2005)
Nature
, vol.435
, pp. 839-843
-
-
O'Donnell, K.A.1
Wentzel, E.A.2
Zeller, K.I.3
Dang, C.V.4
Mendell, J.T.5
-
27
-
-
35449003175
-
MicroRNA let-7a down-regulates MYC and reverts MYC-induced growth in Burkitt lymphoma cells
-
Sampson V.B., Rong N.H., Han J., et al. MicroRNA let-7a down-regulates MYC and reverts MYC-induced growth in Burkitt lymphoma cells. Cancer Res 2007, 67:9762-9770.
-
(2007)
Cancer Res
, vol.67
, pp. 9762-9770
-
-
Sampson, V.B.1
Rong, N.H.2
Han, J.3
-
28
-
-
84855779125
-
Hsa-let-7a functions as a tumor suppressor in renal cell carcinoma cell lines by targeting c-myc
-
Liu Y., Yin B., Zhang C., Zhou L., Fan J. Hsa-let-7a functions as a tumor suppressor in renal cell carcinoma cell lines by targeting c-myc. Biochem Biophys Res Commun 2012, 417:371-375.
-
(2012)
Biochem Biophys Res Commun
, vol.417
, pp. 371-375
-
-
Liu, Y.1
Yin, B.2
Zhang, C.3
Zhou, L.4
Fan, J.5
-
29
-
-
36549026364
-
Prediction and preliminary validation of oncogene regulation by miRNAs
-
Koscianska E., Baev V., Skreka K., et al. Prediction and preliminary validation of oncogene regulation by miRNAs. BMC Mol Biol 2007, 8:79.
-
(2007)
BMC Mol Biol
, vol.8
, pp. 79
-
-
Koscianska, E.1
Baev, V.2
Skreka, K.3
-
30
-
-
37549008310
-
Widespread microRNA repression by Myc contributes to tumorigenesis
-
Chang T.C., Yu D., Lee Y.S., et al. Widespread microRNA repression by Myc contributes to tumorigenesis. Nat Genet 2008, 40:43-50.
-
(2008)
Nat Genet
, vol.40
, pp. 43-50
-
-
Chang, T.C.1
Yu, D.2
Lee, Y.S.3
-
31
-
-
72449154270
-
Embryonic stem cell microRNAs: defining factors in induced pluripotent (iPS) and cancer (CSC) stem cells?
-
Gunaratne P.H. Embryonic stem cell microRNAs: defining factors in induced pluripotent (iPS) and cancer (CSC) stem cells?. Curr Stem Cell Res Ther 2009, 4:168-177.
-
(2009)
Curr Stem Cell Res Ther
, vol.4
, pp. 168-177
-
-
Gunaratne, P.H.1
-
32
-
-
62549160957
-
Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation
-
Chang T.C., Zeitels L.R., Hwang H.W., et al. Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation. Proc Natl Acad Sci USA 2009, 106:3384-3389.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 3384-3389
-
-
Chang, T.C.1
Zeitels, L.R.2
Hwang, H.W.3
-
33
-
-
79954842560
-
Let-7 family miRNAs regulate estrogen receptor alpha signaling in estrogen receptor positive breast cancer
-
Zhao Y., Deng C., Wang J., et al. Let-7 family miRNAs regulate estrogen receptor alpha signaling in estrogen receptor positive breast cancer. Breast Cancer Res Treat 2011, 127:69-80.
-
(2011)
Breast Cancer Res Treat
, vol.127
, pp. 69-80
-
-
Zhao, Y.1
Deng, C.2
Wang, J.3
-
34
-
-
68649089561
-
Estrogen regulation of MicroRNA expression
-
Klinge C.M. Estrogen regulation of MicroRNA expression. Curr Genomics 2009, 10:169-183.
-
(2009)
Curr Genomics
, vol.10
, pp. 169-183
-
-
Klinge, C.M.1
-
35
-
-
84860386584
-
MiRNAs and estrogen action
-
Klinge C.M. MiRNAs and estrogen action. Trends Endocrinol Metab 2012, 23:223-233.
-
(2012)
Trends Endocrinol Metab
, vol.23
, pp. 223-233
-
-
Klinge, C.M.1
-
36
-
-
79958225650
-
MicroRNAs in NF-κB signaling
-
Ma X., Becker Buscaglia L.E., Barker J.R., Li Y. MicroRNAs in NF-κB signaling. J Mol Cell Biol 2011, 3:159-166.
-
(2011)
J Mol Cell Biol
, vol.3
, pp. 159-166
-
-
Ma, X.1
Becker Buscaglia, L.E.2
Barker, J.R.3
Li, Y.4
-
37
-
-
70350784147
-
Transformation locked in a loop
-
Drost J., Agami R. Transformation locked in a loop. Cell 2009, 139:654-656.
-
(2009)
Cell
, vol.139
, pp. 654-656
-
-
Drost, J.1
Agami, R.2
-
38
-
-
70350778443
-
An epigenetic switch involving NF-κB, Lin28, Let-7 MicroRNA, and IL6 links inflammation to cell transformation
-
Iliopoulos D., Hirsch H.A., Struhl K. An epigenetic switch involving NF-κB, Lin28, Let-7 MicroRNA, and IL6 links inflammation to cell transformation. Cell 2009, 139:693-706.
-
(2009)
Cell
, vol.139
, pp. 693-706
-
-
Iliopoulos, D.1
Hirsch, H.A.2
Struhl, K.3
-
39
-
-
70350778443
-
An epigenetic switch involving NF-kappaB, Lin28, Let-7 MicroRNA, and IL6 links inflammation to cell transformation
-
Iliopoulos D., Hirsch H.A., Struhl K. An epigenetic switch involving NF-kappaB, Lin28, Let-7 MicroRNA, and IL6 links inflammation to cell transformation. Cell 2009, 139:693-706.
-
(2009)
Cell
, vol.139
, pp. 693-706
-
-
Iliopoulos, D.1
Hirsch, H.A.2
Struhl, K.3
-
40
-
-
79958835291
-
MiR-9 and let-7g enhance the sensitivity to ionizing radiation by suppression of NFkappaB1
-
Arora H., Qureshi R., Jin S., Park A.K., Park W.Y. MiR-9 and let-7g enhance the sensitivity to ionizing radiation by suppression of NFkappaB1. Exp Mol Med 2011, 43:298-304.
-
(2011)
Exp Mol Med
, vol.43
, pp. 298-304
-
-
Arora, H.1
Qureshi, R.2
Jin, S.3
Park, A.K.4
Park, W.Y.5
-
41
-
-
84862833021
-
Estrogen receptor-regulated microRNAs contribute to the BCL2/BAX imbalance in endometrial adenocarcinoma and precancerous lesions
-
Zhang R., He Y., Zhang X., et al. Estrogen receptor-regulated microRNAs contribute to the BCL2/BAX imbalance in endometrial adenocarcinoma and precancerous lesions. Cancer Lett 2012, 314:155-165.
-
(2012)
Cancer Lett
, vol.314
, pp. 155-165
-
-
Zhang, R.1
He, Y.2
Zhang, X.3
-
42
-
-
51749088101
-
Let-7a microRNA suppresses therapeutics-induced cancer cell death by targeting caspase-3
-
Tsang W.P., Kwok T.T. Let-7a microRNA suppresses therapeutics-induced cancer cell death by targeting caspase-3. Apoptosis 2008, 13:1215-1222.
-
(2008)
Apoptosis
, vol.13
, pp. 1215-1222
-
-
Tsang, W.P.1
Kwok, T.T.2
|