TFII-I regulates target genes in the PI-3K and TGF-β signaling pathways through a novel DNA binding motif

Gene

Volumn 527, Issue 2, 2013, Pages 529-536

  Segura Puimedon, Maria ^a,b   Borralleras, Cristina ^a,b,c   Pérez Jurado, Luis A ^a,b,c   Campuzano, Victoria ^a,b,c  

^a UNIVERSITAT POMPEU FABRA   (Spain)

^b CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED DE ENFERMEDADES RARAS CIBERER   (Spain)

^c HOSPITAL DEL MAR   (Spain)

Author keywords

DNA binding domain; Embryonic stem cells; Mouse model; TFII I; Transcriptional regulation; Williams Beuren syndrome

Indexed keywords

GENERAL TRANSCRIPTION FACTOR; GENERAL TRANSCRIPTION FACTOR 1; PHOSPHATIDYLINOSITOL 3 KINASE; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CHROMATIN IMMUNOPRECIPITATION; DNA BINDING MOTIF; EMBRYO CELL; GENE CONTROL; GENE EXPRESSION; GENE IDENTIFICATION; GENE TARGETING; GENETIC SCREENING; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; REAL TIME POLYMERASE CHAIN REACTION; WILD TYPE;

ACGH; CHIP; CHROMATINE IMMUNOPRECIPITATION; CNVS; COPY NUMBER VARIANTS; DEG; DIFFERENTIALLY EXPRESSED GENES; DNA BINDING DOMAIN; EMBRYONIC STEM CELLS; ES; GENERAL TRANSCRIPTION FACTOR II-I; MEFS; MICROARRAY COMPARATIVE GENOME HYBRIDIZATION; MOUSE EMBRYONIC FIBROBLAST; MOUSE MODEL; NERVE GROWTH FACTOR; NGF; QRT-PCR; QUANTITATIVE REAL-TIME POLYMERASE CHAIN REACTION; TFII-I; TRANSCRIPTIONAL REGULATION; WBS; WILLIAMS-BEUREN SYNDROME;

ANIMALS; BASE SEQUENCE; BINDING SITES; DNA; HUMANS; MICE; PHOSPHATIDYLINOSITOL 3-KINASES; PROMOTER REGIONS, GENETIC; REAL-TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS, TFII; TRANSFORMING GROWTH FACTOR BETA;

MUS;

EID: 84881542269     PISSN: 03781119     EISSN: 18790038     Source Type: Journal    
DOI: 10.1016/j.gene.2013.06.050     Document Type: Article

References (48)

1. Antonell A., et al. Partial 7q11.23 deletions further implicate GTF2I and GTF2IRD1 as the main genes responsible for the Williams-Beuren syndrome neurocognitive profile. J. Med. Genet. 2010, 47:312-320.
2. Antonell A., et al. Transcriptome profile in Williams-Beuren syndrome lymphoblast cells reveals gene pathways implicated in glucose intolerance and visuospatial construction deficits. Hum. Genet. 2010, 128:27-37.
3. Ashworth T., et al. Cutting edge: TFII-I controls B cell proliferation via regulating NF-kappaB. J. Immunol. 2007, 178:2631-2635.
4. Bailey T.L., et al. Fitting a mixture model by expectation maximization to discover motifs in biopolymers. Proc. Int. Conf. Intell. Syst. Mol. Biol. 1994, 2:28-36.
5. Bayarsaihan D., et al. Epigenetic modulation by TFII-I during embryonic stem cell differentiation. J. Cell. Biochem. 2012, 113:3056-3060.
6. Breitkreutz B.J., et al. AFM 4.0: a toolbox for DNA microarray analysis. Genome Biol. 2001, 2. (SOFTWARE0001).
7. Caraveo G., et al. Action of TFII-I outside the nucleus as an inhibitor of agonist-induced calcium entry. Science 2006, 314:122-125.
8. Cheriyath V., et al. Structure-function analysis of TFII-I. Roles of the N-terminal end, basic region, and I-repeats. J. Biol. Chem. 2001, 276:8377-8383.
9. Chimge N.O., et al. Expression profiling of BEN regulated genes in mouse embryonic fibroblasts. J. Exp. Zool. B Mol. Dev. Evol. 2007, 308:209-224.
10. Chimge N.O., et al. Gene expression analysis of TFII-I modulated genes in mouse embryonic fibroblasts. J. Exp. Zool. B Mol. Dev. Evol. 2007, 308:225-235.
11. Chimge N.O., et al. Identification of the TFII-I family target genes in the vertebrate genome. Proc. Natl. Acad. Sci. U. S. A. 2008, 105:9006-9010.
12. Chimge N.O., et al. PI3K/Akt-dependent functions of TFII-I transcription factors in mouse embryonic stem cells. J. Cell. Biochem. 2012, 113:1122-1131.
13. Dai L., et al. Is it Williams syndrome? GTF2IRD1 implicated in visual-spatial construction and GTF2I in sociability revealed by high resolution arrays. Am. J. Med. Genet. A 2009, 149A:302-314.
14. Diez H., et al. Specific roles of Akt iso forms in apoptosis and axon growth regulation in neurons. PLoS One 2012, 7:e32715.
15. Enkhmandakh B., et al. Essential functions of the Williams-Beuren syndrome-associated TFII-I genes in embryonic development. Proc. Natl. Acad. Sci. U. S. A. 2009, 106:181-186.
16. Ferrero G.B., et al. An atypical 7q11.23 deletion in a normal IQ Williams-Beuren syndrome patient. Eur. J. Hum. Genet. 2010, 18:33-38.
17. Henrichsen C.N., et al. Copy number variants, diseases and gene expression. Hum. Mol. Genet. 2009, 18:R1-R8.
18. Henrichsen C.N., et al. Using transcription modules to identify expression clusters perturbed in Williams-Beuren syndrome. PLoS Comput. Biol. 2011, 7:e1001054.
19. Huang da W., et al. Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists. Nucleic Acids Res. 2009, 37:1-13.
20. Huang da W., et al. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat. Protoc. 2009, 4:44-57.
21. Irizarry R.A., et al. Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics 2003, 4:249-264.
22. Kamburov A., et al. ConsensusPathDB-a database for integrating human functional interaction networks. Nucleic Acids Res. 2009, 37:D623-D628.
23. Ku M., et al. Positive and negative regulation of the transforming growth factor beta/activin target gene goosecoid by the TFII-I family of transcription factors. Mol. Cell. Biol. 2005, 25:7144-7157.
24. Lazebnik M.B., et al. Williams-Beuren syndrome-associated transcription factor TFII-I regulates osteogenic marker genes. J. Biol. Chem. 2009, 284:36234-36239.
25. Li H.H., et al. Induced chromosome deletions cause hypersociability and other features of Williams-Beuren syndrome in mice. EMBO Mol. Med. 2009, 1:50-65.
26. Lucena J., et al. Essential role of the N-terminal region of TFII-I in viability and behavior. BMC Med. Genet. 2010, 11:61.
27. Makeyev A.V., et al. Molecular basis of Williams-Beuren syndrome: TFII-I regulated targets involved in craniofacial development. Cleft Palate Craniofac. J. 2010, 48:109-116.
28. Makeyev A.V., et al. ChIP-Chip identifies SEC23A, CFDP1 and NSD1 as TFII-I target genes in human neural crest progenitor cells. Cleft Palate Craniofac. J. 2013, 50:347-350.
29. Misra U.K., et al. Transcription factor TFII-I causes transcriptional upregulation of GRP78 synthesis in prostate cancer cells. J. Cell. Biochem. 2009, 106:381-389.
30. Morris C.A. The behavioral phenotype of Williams syndrome: a recognizable pattern of neurodevelopment. Am. J. Med. Genet. C Semin. Med. Genet. 2010, 154C:427-431.
31. Morris C.A., et al. Natural history of Williams syndrome: physical characteristics. J. Pediatr. 1988, 113:318-326.
32. Ogura Y., et al. TFII-I down-regulates a subset of estrogen-responsive genes through its interaction with an initiator element and estrogen receptor alpha. Genes Cells 2006, 11:373-381.
33. Ouyang Z., et al. ChIP-Seq of transcription factors predicts absolute and differential gene expression in embryonic stem cells. Proc. Natl. Acad. Sci. U. S. A. 2009, 106:21521-21526.
34. Palmer S.J., et al. GTF2IRD2 from the Williams-Beuren critical region encodes a mobile element-derived fusion protein that antagonizes the action of its related family members. J. Cell Sci. 2012, 125:5040-5050.
35. Parker R., et al. Identification of TFII-I as the endoplasmic reticulum stress response element binding factor ERSF: its autoregulation by stress and interaction with ATF6. Mol. Cell. Biol. 2001, 21:3220-3233.
36. Patterson R.L., et al. Phospholipase C-gamma is required for agonist-induced Ca2+ entry. Cell 2002, 111:529-541.
37. Pober B.R. Williams-Beuren syndrome. N. Engl. J. Med. 2010, 362:239-252.
38. Proulx E., et al. Enhanced prefrontal serotonin 5-HT(1A) currents in a mouse model of Williams-Beuren syndrome with low innate anxiety. J. Neurodev. Disord. 2010, 2:99-108.
39. Roy A.L. Biochemistry and biology of the inducible multifunctional transcription factor TFII-I. Gene 2001, 274:1-13.
40. Roy A.L. Signal-induced functions of the transcription factor TFII-I. Biochim. Biophys. Acta 2007, 1769:613-621.
41. Roy A.L., et al. Cloning of an inr- and E-box-binding protein, TFII-I, that interacts physically and functionally with USF1. EMBO J. 1997, 16:7091-7104.
42. Rozen S., et al. Primer3 on the WWW for general users and for biologist programmers. Methods Mol. Biol. 2000, 132:365-386.
43. Sakurai T., et al. Haploinsufficiency of Gtf2i, a gene deleted in Williams Syndrome, leads to increases in social interactions. Autism Res. 2011, 4:28-39.
44. Smyth G.K. Linear models and empirical bayes methods for assessing differential expression in microarray experiments. Stat. Appl. Genet. Mol. Biol. 2004, 3. (Article3).
45. Stasyk T., et al. Phosphoproteome profiling of transforming growth factor (TGF)-beta signaling: abrogation of TGFbeta1-dependent phosphorylation of transcription factor-II-I (TFII-I) enhances cooperation of TFII-I and Smad3 in transcription. Mol. Biol. Cell 2005, 16:4765-4780.
46. Tantin D., et al. Regulation of immunoglobulin promoter activity by TFII-I class transcription factors. J. Biol. Chem. 2004, 279:5460-5469.
47. Tassabehji M. Williams-Beuren syndrome: a challenge for genotype-phenotype correlations. Hum. Mol. Genet. 2003, 12:R229-R237. (Spec No 2).
48. Wakaguri H., et al. DBTSS: database of transcription start sites, progress report 2008. Nucleic Acids Res. 2008, 36:D97-D101.