Late radiation injury to peripheral nerves

Handbook of Clinical Neurology

Volumn 115, Issue , 2013, Pages 743-758

  Pradat, Pierre François ^a   Delanian, Sylvie ^b  

^a PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^b SAINT LOUIS HOSPITAL   (France)

Author keywords

Cavernoma; Clodronate; Fibrosis; Neurotoxicity; Pentoxifylline; Plexopathy; Radiculopathy; Radiotherapy; Schwannoma; Tocopherol

Indexed keywords

CLODRONIC ACID; PENTOXIFYLLINE; TOCOPHEROL;

ARTICLE; CAVERNOMA; FIBROSIS; HUMAN; NEURILEMOMA; NEUROTOXICITY; PERIPHERAL NEUROPATHY; PLEXOPATHY; RADIATION INJURY; RADICULOPATHY; RADIOTHERAPY;

CAVERNOMA; CLODRONATE; FIBROSIS; NEUROTOXICITY; PENTOXIFYLLINE; PLEXOPATHY; RADICULOPATHY; RADIOTHERAPY; SCHWANNOMA; TOCOPHEROL;

HUMANS; PERIPHERAL NERVOUS SYSTEM DISEASES; RADIATION INJURIES;

EID: 84881535308     PISSN: 00729752     EISSN: None     Source Type: Book Series    
DOI: 10.1016/B978-0-444-52902-2.00043-6     Document Type: Chapter

References (105)

1. Annane D., Depondt J., Aubert P., et al. Hyperbaric oxygen therapy for radionecrosis of the jaw: a randomized placebo-controlled, double blind, trial from the ORN96 Study Group. J Clin Oncol 2004, 22:4893-4900.
2. Avila E.K., Goenka A., Fontenla S. Bilateral phrenic nerve dysfunction: a late complication of mantle irradiation. J Neurooncol 2011, 103:393-395.
3. Azinovic I., Martinez Monge R., Javier Aristu J., et al. Intraoperative radiotherapy electron boost followed by moderate doses of external beam radiotherapy in resected soft-tissue sarcoma of the extremities. Radiother Oncol 2003, 67:331-337.
4. Bagley F.H., Walsh J.W., Cady B., et al. Carcinomatous versus radiation-induced brachial plexus neuropathy in breast cancer. Cancer 1978, 41:2154-2157.
5. Bajrovic A., Rades D., Fehlauer F., et al. Is there a life-long risk of brachial plexopathy after radiotherapy of supraclavicular lymph nodes in breast cancer patients?. Radiother Oncol 2004, 71:297-301.
6. Ballian N., Androulakis I.I., Chatzistefanou K., et al. Optic neuropathy following radiotherapy for Cushing's disease: case report and literature review. Hormones (Athens) 2010, 9:269-273.
7. Beglu E., Kurland L., Mulder D., et al. Brachial plexus neuropathy in the population of Rochester, Minessota 1970-1981. Ann Neurol 1985, 18:320-323.
8. Bennett M., Feldmeier J., Hampson N., et al. Hyperbaric oxygen therapy for late radiation tissue injury. Cochrane Database Syst Rev 2005, 3CD005005.
9. Berger P., Bataïni J.P. Radiation-induced nerve palsy. Cancer 1977, 48:152-155.
10. Bergstrom R. Changes in peripheral nerve tissue after irradiation with high energy protons. Acta Radiol 1962, 58:301-312.
11. Bhandare N., Jackson A., Eisbruch A., et al. Radiation therapy and hearing loss. Int J Radiat Oncol Biol Phys 2010, 76:S50-S57.
12. Brydoy M., Storstein A., Dahl O. Transient neurological adverse effects following low dose radiation therapy for early stage testicular seminoma. Radiother Oncol 2007, 82:137-144.
13. Carl U., Feldmeier J., Schmitt G., et al. Hyperbaric oxygen therapy for late sequelae in women receiving radiation after breast-conserving surgery. Int J Radiat Oncol Biol Phys 2001, 49:1029-1031.
14. Cavanagh J.B. Effects of x-irradiation on the proliferation of cells in peripheral nerve during Wallerian degeneration in the rat. Br J Radiol 1968, 41:275-281.
15. Chan R.C., Shukovsky L.J. Effects of irradiation on the eye. Radiology 1976, 120:673-675.
16. Char D.H., Lonn L.I., Margolis L.W. Complications of cobalt plaque therapy of choroidal malanomas. Am J Ophthalmol 1977, 84:536-541.
17. Chen Y.-L., DeLaney T. Peripheral nerves. Human Radiation Injury 2011, 236-245. Lippincott Williams Wilkins, Philadelphia. D.C. Shrieve, J.S. Loeffler (Eds.).
18. Churn M., Clough V., Slater A. Early onset of bilateral brachial plexopathy during mantle radiotherapy for Hodgkin disease. Clin Oncol 2000, 12:289-291.
19. Cosset J.-M. Breur Gold Medal Award Lecture 2001: irradiation accidents lessons for oncology. Radiother Oncol 2002, 63:1-10.
20. Craswell P.W. Vocal cord paresis following radioactive iodine therapy. Br J Clin Pract 1972, 26:571-572.
21. Croisile B., Piperno D., Bascoulergue Y., et al. Chiasmal radionecrosis after irradiation of the sella turcica using a conventional dosage. Contribution of magnetic resonance imaging. Rev Neurol (Paris) 1990, 146:57-60.
22. Dahele M., Davey P., Reingold S., et al. Radiation- induced lumbosacral plexopathy: an important enigma. Clin Oncol 2006, 18:427-428.
23. Danesh-Meyer H.V. Radiation-induced optic neuropathy. J Clin Neurosci 2008, 15:95-100.
24. Davila L., Delattre J.Y., Said G., et al. An experimental model of radiation-induced neuropathy and plexopathy. Neurology 1990, 40:277.
25. De Carolis P., Montagna P., Cipulli M., et al. Isolated lower motoneuron involvement following radiotherapy. J Neurol Neurosurg Psychiatry 1986, 49:718-719.
26. Delanian S., Lefaix J.-L. The radiation-induced fibroatrophic process: therapeutic perspective via the antioxidant pathway. Radiother Oncol 2004, 73:119-131.
27. Delanian S., Lefaix J.-L. Current management for late normal tissue injury: radiation-induced fibrosis and necrosis. Sem Radiat Oncol 2007, 17:99-107.
28. Delanian S., Pradat P.-F. A posteriori conformal radiotherapy using 3D dosimetric reconstitution in a survivor of adult-onset Hodgkin's disease for definitive diagnosis of a lower motor neuron disease. J Clin Oncol 2010, 28:599-601.
29. Delanian S., Balla-Mekias S., Lefaix J.-L. Striking regression of chronic radiotherapy damage in a clinical trial of combined pentoxifylline and tocopherol. J Clin Oncol 1999, 17:3283-3290.
30. Delanian S., Porcher R., Balla-Mekias S., et al. Randomized placebo-controlled trial of combined pentoxifylline and tocopherol for regression of superficial radiation-induced fibrosis. J Clin Oncol 2003, 21:2545-2550.
31. Delanian S., Porcher R., Rudant J., et al. Kinetics of response to long term treatment combining pentoxifylline and tocopherol in patients with superficial radiation-induced fibrosis. J Clin Oncol 2005, 23:8570-8579.
32. Delanian S., Depondt J., Lefaix J.-L. Major healing of refractory mandible osteoradionecrosis after treatment combining pentoxifylline and tocopherol: a phase II trial. Head Neck 2005, 27:114-123.
33. Delanian S., Lefaix J.L., Maisonobe T., et al. Significant clinical improvement in radiation-induced lumbosacral polyradiculopathy by a treatment combining pentoxifylline, tocopherol, and clodronate (PENTOCLO). J Neurol Sci 2008, 275:164-166.
34. Delanian S., Chatel C., Porcher R., et al. Complete restoration of refractory mandibular osteoradionecrosis by prolonged treatment with a pentoxifylline-tocopherol-clodronate combination (PENTOCLO): a phase II trial. Int J Radiat Oncol Biol Phys 2011, 80:832-839.
35. Delattre J.Y., Poisson M., Pertuiset B.F., et al. Necrosis of the optic tract, hypothalamus and brain stem after irradiation of a pituitary adenoma with conventional doses. Rev Neurol (Paris) 1986, 142:232-237.
36. Demizu Y., Murakami M., Miyawaki D., et al. Analysis of vision loss caused by radiation-induced optic neuropathy after particle therapy for head-and-neck and skull-base tumors adjacent to optic nerves. Int J Radiat Oncol Biol Phys 2009, 75:487-492.
37. Denham J., Hauer-Jensen M. The radiotherapeutic injury: a complex wound. Radiother Oncol 2002, 63:129-145.
38. Diaz J.M., Urban E.S., Schiffman J.S., et al. Post-irradiation neuromyotonia affecting trigeminal nerve distribution: an unusual presentation. Neurology 1992, 42:1102-1104.
39. Donohue W.L., Jaffe F.A., Rewcastle N.B. Radiation induced neurofibromata. Cancer 1967, 20:589-595.
40. Dropcho E.J. Neurotoxicity of radiation therapy. Neurol Clin 2010, 28:217-234.
41. Ducatman B., Scheithauer B. Postirradiation neurofibrosarcoma. Cancer 1983, 51:1028-1033.
42. Ducray F., Guillevin R., Psimaras D., et al. Post-radiation lumbosacral radiculopathy with spinal root cavernomas mimicking carcinomatous meningitis. Neuro Oncol 2008, 10:1035-1039.
43. Evans M., Graham M., Mahler P., et al. Use of steroids to suppress vascular response to radiation. Int J Radiat Oncol Biol Phys 1987, 13:563-567.
44. Fathers E., Trush D. Radiation-induced brachial plexopathy in women treated for carcinoma of the breast. Clin Rehabil 2002, 16:160-165.
45. Feistner H., Weissenborn K., Munte T.F., et al. Post-irradiation lesions of the caudal roots. Acta Neurol Scand 1989, 80:277-281.
46. Fishman M.L., Bean S.C., Cogan D.G. Optic atrophy following prophylactic chemotherapy and cranial radiation for acute lymphocytic leukemia. Am J Ophthalmol 1976, 82:571-576.
47. Flickinger J.C., Pollock B.E., Kondziolka D., et al. Does increased nerve length within the treatment volume improve trigeminal neuralgia radiosurgery? A prospective double-blind, randomized study. Int J Radiat Oncol Biol Phys 2001, 51:449-454.
48. Foley K.M., Woodruff J.M., Ellis F.T., et al. Radiation-induced malignant and atypical peripheral nerve sheath tumors. Ann Neurol 1980, 7:311-318.
49. Furby A., Behin A., Lefaucheur J.P., et al. Late-onset cervicoscapular muscle atrophy and weakness after radiotherapy for Hodgkin disease: a case series. J Neurol Neurosurg Psychiatry 2010, 81:101-104.
50. Gerard J.M., Franck N., Moussa Z., et al. Acute ischemic brachial plexus neuropathy following radiation therapy. Neurology 1989, 39:450-451.
51. Gilette E.L., Mahler P.A., Powers D.V.M., et al. Late radiation injury to muscle and peripheral nerves (Late Effects Consensus Conference). Int J Radiat Oncol Biol Phys 1995, 31:1309-1318.
52. Glantz M., Burger P., Friedman A., et al. Treatment of radiation-induced nervous system injury with heparin and warfarin. Neurology 1994, 44:2020-2027.
53. Guy J., Schatz N.J. Hyperbaric oxygen in the treatment of radiation-induced optic neuropathy. Ophthalmology 1986, 93:1083-1088.
54. Habrand J.L., Austin-Seymour M., Birnbaum S., et al. Neurovisual outcome following proton radiation therapy. Int J Radiat Oncol Biol Phys 1989, 16:1601-1606.
55. Harper C.M., Thomas J.E., Cascino T.L., et al. Distinction between neoplastic and radiation-induced brachial plexopathy, with emphasis on the role of EMG. Neurology 1989, 39:502-506.
56. Hassler O. Cellular kinetics of the peripheral nerve and striated muscle after single dose of x-rays. Zellforsch 1968, 85:62-66.
57. Hsia A.W., Katz J.S., Hancock S.L., et al. Post-irradiation polyradiculopathy mimics leptomeningeal tumor on MRI. Neurology 2003, 60:1694-1696.
58. Janzen A., Warren S. Effect of roentgen rays on the peripheral nerve of the rat. Radiology 1942, 38:333-337.
59. Jiang G., Tucker S., Guttenberg R., et al. Radiation-induced injury to the visual pathway. Radiother Oncol 1994, 30:17-25.
60. Johnson E., Hammond A., Cairncross J. Bilateral hypoglossal palsies: a late complication of curative radiotherapy. Can J Neurol Sci 1989, 16:198-199.
61. Kinsella T.J., Sindelar W.F., DeLuca A.M., et al. Tolerance of peripheral nerve to intra-operative radiotherapy (IORT): clinical and experimental studies. Int J Radiat Oncol Biol Phys 1985, 11:1579-1585.
62. Kinsella T.J., Sindelar W.F., Lack E., et al. Preliminary results of a randomized study of adjuvant radiation therapy in resectable adult retroperitoneal soft tissue sarcomas. J Clin Oncol 1988, 6:18-25.
63. Kinsella T.J., DeLuca A.M., Barnes M., et al. Threshold dose for peripheral neuropathy following intraoperative radiotherapy (IORT) in a large animal model. Int J Radiat Oncol Biol Phys 1991, 20:697-701.
64. Kong L., Lu J.J., Liss A., et al. Radiation-induced cranial nerve palsy: a cross-sectional study of nasopharyngeal cancer patients after definitive radiotherapy. Int J Radiat Oncol Biol Phys 2010, 79:1421-1427.
65. Labauge P., Lefloch A., Chapon F., et al. Postirradiation spinal root cavernoma. Eur Neurol 2006, 56:256-257.
66. Lamy C., Mas J., Varet B., et al. Postradiation lower motor neuron syndrome presenting as monomelic amyotrophy. J Neurol Neurosurg Psychiatry 1991, 54:648-649.
67. Lefaix J.-L., Delanian S., Vozenin M.-C., et al. Striking regression of subcutaneous fibrosis induced by high doses of gamma rays using a combination of pentoxifylline and alpha-tocopherol: an experimental study. Int J Radiat Oncol Biol Phys 1999, 43:839-847.
68. Lefevre-Houller C., Willer J.C., Delattre J.Y., et al. Neurotonie post-irradiation of the messeter. Rev Neurol (Paris) 2004, 160:1075-1077.
69. Lessell S., Lessell I.M., Rizzo J.F. Ocular neuromyotonia after radiation therapy. Am J Ophthalmol 1986, 102:766-770.
70. Liu L.H., Chen C.W., Chang M.H. Post-irradiation myokymia and neuromyotonia in unilateral tongue and mentalis muscles: report of a case. Acta Neurol Taiwan 2007, 16:33-36.
71. Martin M., Lefaix J.-L., Delanian S. TGF-β1 and radiation fibrosis: a master switch and a specific therapeutic target?. Int J Radiat Oncol Biol Phys 2000, 47:277-290.
72. Match R.M. Radiation-induced brachial plexus paralysis. Arch Surg 1975, 110:384-386.
73. Mendes D., Nawalkar R., Eldar S. Post irradiation femoral neuropathy. J Bone Joint Surg 1991, 73A:137-140.
74. Much J.W., Weber E.D., Newman S.A. Ocular neuromyotonia after gamma knife stereotactic radiation therapy. J Neuroophthalmol 2009, 29:136-139.
75. Mumenthaler M., Narakas A., Gilliatt R. Brachial plexus disorders. Peripheral Neuropathy 1984, 1383-1424. W.B. Saunders, Philadelphia. P.J. Dyck, P.K. Thomas, E.H. Lambert, R. Bunge (Eds.).
76. Parsons J.T., Bova F., Fitzgerald C., et al. Radiation optic neuropathy after megavoltage external-beam irradiation: analysis of time-dose factors. Int J Radiat Oncol Biol Phys 1994, 30:755-763.
77. Paulino A.C. Late effects of radiotherapy for pediatric extremity sarcomas. Int J Radiat Oncol Biol Phys 2004, 60:265-274.
78. Pettigrew L.C., Glass J.P., Maor M., et al. Diagnosis and treatment of lumbosacral plexopathies in patients with cancer. Arch Neurol 1984, 41:1282-1285.
79. Pierce S.M., Recht A., Lingos T.I., et al. Long-term radiation complications following conservative surgery (CS) and radiation therapy (RT) in patients with early stage breast cancer. Int J Radiat Oncol Biol Phys 1992, 23:915-923.
80. Pieters R.S., Niemierko A., Fullerton B.C., et al. Cauda equina tolerance to high-dose fractionated irradiation. Int J Radiat Oncol Biol Phys 2006, 64:251-257.
81. Powell S., Cooke J., Parsons C. Radiation-induced brachial plexus injury: follow-up of two different fractionation schedules. Radiother Oncol 1990, 18:213-220.
82. Pradat P.F., Poisson M., Delattre J.Y. Radiation-induced neuropathies. Experimental and clinical data. Rev Neurol (Paris) 1994, 150:664-677.
83. Pradat P.F., Bouche P., Delanian S. Sciatic nerve moneuropathy: an unusual late effect of radiotherapy. Muscle Nerve 2009, 40:872-874.
84. Pritchard J., Anand P., Broome J., et al. Double-blind randomized phase II study of hyperbaric oxygen in patients with radiation-induced brachial plexopathy. Radiother Oncol 2001, 58:279-286.
85. Pugliese G., Green R., Antonacci A. Radiation-induced long thoracic nerve palsy. Cancer 1987, 60:1247-1248.
86. Robbins M., Zhao W. Chronic oxidative stress and radiation-induced normal tissue injury: a review. Int J Radiat Biol 2004, 80:251-259.
87. Roden D., Bosley T.M., Fowble B., et al. Delayed radiation injury to the retrobulbar optic nerves and chiasm. Clinical syndrome and treatment with hyperbaric oxygen and corticosteroids. Ophthalmology 1990, 97:346-351.
88. Roth G., Magistris M.R., Le Fort D., et al. Post-radiation branchial plexopathy. Persistent conduction block. Myokymic discharges and cramps. Rev Neurol (Paris). 1988, 144:173-180.
89. Rowin J., Cheng G., Lewis S.L., et al. Late appearance of dropped head syndrome after radiotherapy for Hodgkin's disease. Muscle Nerve 2006, 34:666-669.
90. Russell K.J., Laramore G.E., Krieger J.N., et al. Transient and chronic neurological complications of fast neutron radiation for adenocarcinoma of the prostate. Radiother Oncol 1990, 18:257-265.
91. Salner A.L., Botnick L.E., Herzog A.G., et al. Reversible brachial plexopathy following primary radiation therapy for breast cancer. Cancer Treat Rep 1981, 65:797-802.
92. Schiødt A.V., Kristensen O. Neurologic complications after irradiation of malignant tumors of the testis. Acta Radiol Oncol Radiat Phys Biol 1978, 17:369-378.
93. Soto O. Radiation-induced conduction block: resolution following anticoagulant therapy. Muscle Nerve 2005, 31:642-645.
94. Stafford S.L., Pollock B., Leavitt J., et al. A study of the radiation tolerance of the optic nerves and chiasm after stereotactic radiosurgery. Int J Radiat Oncol Biol Phys 2003, 55:1177-1181.
95. Teixeira M.J., Fonoff E., Montenegro M. Dorsal root entry zone lesions for treatment of pain-related to radiation-induced plexopathy. Spine 2007, 32:E316-E319.
96. Thomas J.E., Colby M.Y. Radiation-induced or metastatic brachial plexopathy? A diagnosis dilemma. JAMA 1972, 222:1392-1395.
97. Thomas J.E., Cascino T.L., Earle J.D. Differential diagnosis between radiation and tumor plexopathy of the pelvis. Neurology 1985, 35:1-7.
98. Tishler R.B., Loeffler J.S., Lunsford L.D., et al. Tolerance of cranial nerves of the cavernous sinus to radiosurgery. Int J Radiat Oncol Biol Phys 1993, 27:215-221.
99. Tsang K.L., Fong K.Y., Ho S.L. Localized neuromyotonia of neck muscles after radiotherapy for nasopharyngeal carcinoma. Mov Disord 1999, 14:1047-1049.
100. Westbrook K., Ballantyne A., Eckles M., et al. Breast cancer and vocal cord paralysis. South Med J 1974, 67:805-807.
101. Williamson R., Kondziolka D., Kanaan H., et al. Adverse radiation effects after radiosurgery may benefit from oral vitamin E and pentoxifylline therapy: a pilot study. Stereotact Funct Neurosurg 2008, 86:359-366.
102. Wilson W.B., Perez G.M., Kleinschmidt-Demasters B.K. Sudden onset of blindness in patients treated with oral CCNU and low-dose cranial irradiation. Cancer 1987, 59:901-907.
103. Young W.C., Thornton A.F., Gebarski S.S., et al. Radiation-induced optic neuropathy: correlation of MR imaging and radiation dosimetry. Radiology 1992, 185:904-907.
104. Zadeh G., Buckle C., Shannon P., et al. Radiation induced peripheral nerve tumors: case series and review of the literature. J Neurooncol 2007, 83:205-212.
105. Zelefsky M.J., Nori D., Shiu M., et al. Limb salvage in soft tissue sarcomas involving neurovascular structures using combined surgical resection and brachytherapy. Int J Radiat Oncol Biol Phys 1990, 19:913-918.