Streptococcal-vimentin cross-reactive antibodies induce microvascular cardiac endothelial proinflammatory phenotype in rheumatic heart disease

Clinical and Experimental Immunology

Volumn 173, Issue 3, 2013, Pages 419-429

  Delunardo, F ^a   Scalzi, V ^b   Capozzi, A ^b   Camerini, S ^a   Misasi, R ^b   Pierdominici, M ^a   Pendolino, M ^b   Crescenzi, M ^a   Sorice, M ^b   Valesini, G ^b   Ortona, E ^a,c   Alessandri, C ^b  

^a ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c Istituto San Raffaele Sulmona   (Italy)

Author keywords

Anti endothelial cell autoantibodies; Rheumatic heart disease; Vimentin

Indexed keywords

AUTOANTIGEN; BACTERIAL PROTEIN; CELL ADHESION MOLECULE; CELL SURFACE PROTEIN; CROSS REACTING ANTIBODY; GROWTH FACTOR; HEAT SHOCK PROTEIN 70; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE; VIMENTIN;

ADOLESCENT; ADULT; AMINO ACID SEQUENCE; ANTIBODY BLOOD LEVEL; ARTICLE; CELL STIMULATION; CHILD; CROSS REACTION; CYTOKINE RELEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOASSAY; IMMUNOBLOTTING; IN VITRO STUDY; MAJOR CLINICAL STUDY; MALE; MASS SPECTROMETRY; MICROVASCULAR ENDOTHELIAL CELL; MOLECULAR CLONING; PHENOTYPE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PURIFICATION; PURIFICATION; RHEUMATIC HEART DISEASE; SCHOOL CHILD; SERUM; STREPTOCOCCUS GROUP A; TWO DIMENSIONAL ELECTROPHORESIS; WESTERN BLOTTING;

ANTI-ENDOTHELIAL CELL AUTOANTIBODIES; RHEUMATIC HEART DISEASE; VIMENTIN;

ADOLESCENT; ADULT; AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES; AUTOANTIBODIES; AUTOANTIGENS; BACTERIAL PROTEINS; CHILD; CROSS REACTIONS; ENDOCARDITIS; ENDOTHELIUM; FEMALE; HUMANS; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; RABBITS; RHEUMATIC HEART DISEASE; RHEUMATOID VASCULITIS; STREPTOCOCCUS; VIMENTIN; YOUNG ADULT;

EID: 84881521316     PISSN: 00099104     EISSN: 13652249     Source Type: Journal    
DOI: 10.1111/cei.12135     Document Type: Article

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