Device factors affecting pulmonary delivery of dry powders

Therapeutic Delivery

Volumn 4, Issue 8, 2013, Pages 939-949

  Smutney, Chad C ^a   Grant, Marshall ^a   Kinsey, P Spencer ^a  

^a MannKind Corporation   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BUDESONIDE; FLUTICASONE; FLUTICASONE PROPIONATE PLUS SALMETEROL; INSULIN; LANINAMIVIR; MOMETASONE FUROATE; PROPIONIC ACID; RECOMBINANT HUMAN INSULIN; SALMETEROL; SALMETEROL XINAFOATE; TIOTROPIUM BROMIDE;

ARTICLE; DRUG DELIVERY SYSTEM; DRUG DOSE REGIMEN; DRY POWDER; DRY POWDER INHALER; HUMAN; INHALATION; MATERIALS TESTING; PRIORITY JOURNAL; RESERVOIR;

EID: 84881516835     PISSN: 20415990     EISSN: 20416008     Source Type: Journal    
DOI: 10.4155/tde.13.77     Document Type: Article

References (21)

1. Patton JS. The lungs as a portal of entry for systemic drug delivery. Proc. Am. Thorac. Soc. 1, 338-344 (2004).
2. Ashish AK. Pulmonary drug delivery system. Int. J. Pharm. Tech. Res. 4(1), 293-305 (2012).
3. Labiris NR. Pulmonary drug delivery. Part I: physiological factors affecting therapeutic effectiveness of aerosolized medications. Br. J. Clin. Pharmacol. 56(6), 588-599 (2003).
4. Frijlink HW. Dry-powder inhalers for pulmonary drug delivery. Expert Opin. Drug Deliv. 1(1), 67-86 (2004).
5. Pfutzner A. Technosphere/insulin - a new approach for effective delivery of human insulin via the pulmonary route. Diabetes Technol. Ther. 4(5), 589-594 (2002).
6. Donovan MJ. Dry-powder inhaler device influence on carrier particle performance. J. Pharm. Sci. 101(3), 1097-1107 (2012).
7. de Boer AH. Air classifier technology (ACT) in dry powder inhalation part 1. Introduction of a novel force distribution concept (FDC) explaining the performance of a basic air classifier on adhesive mixtures. Int. J. Pharm. 260, 187-200 (2003).
8. Telko MJ. Dry-powder inhaler formulation. Respir. Care 50(9), 1209-1227 (2005).
9. Geller DE. Development of an inhaled dry-powder formulation of tobramycin using pulmosphere technology. J. Aersol Med. Pulm. Drug Deliv. 24(4) 175-182 (2011).
10. Koushik K. Particle & device engineering for inhalation drug delivery. Drug Develop. Deliv. 4(2), 2-5 (2004).
11. Chow AH, Tong HH, Chattopadhyay P, Shekunov BY. Particle engineering for pulmonary drug delivery. Pharm. Res. 24(3), 411-437 (2007).
12. Mitchell J. In vitro and in vivo aspects of cascade impactor tests and inhaler perfomance: a review. AAPS PharmSciTech 8(4), 237-248 (2007).
13. Mitchell JP. Laser diffractometry as a technique for the rapid assessment of aerosol particle size from inhalers. J. Aerosol Med. 19(4), 409-433 (2006).
14. de Boer AH. Inhalation characteristics and their effects on in vitro drug delivery from Dry-powder inhalers part 1. Inhalation characteristics, work of breathing and volunteers' preference in dependence of the inhalers resistance. Int. J. Pharm. 130, 231-244 (1996).
15. Smutney CC. Inspiratory efforts achieved in use of the technosphere insulin inhalation system. J. Diabetes Sci. Technol. 3(5), 1175-1182 (2009).
16. Usmani OS. Regional lung deposition and bronchodialator response as a function of b2- agonist particle size. Am. J. Respir. Crit. Care Med. 172(12), 1497-1504 (2005).
17. Svartengren K. Added external resistance reduces oropharyngeal deposition and increases lung deposition of aerosol particles in asthmatics. Am. J. Respir. Crit. Care Med. 152(1), 32-37 (1995).
18. Weiner BB. What is particle size distribution weighting: how to get fooled about what was measured and what it means? (2011). www. brookhaveninstruments.com/pdf/What- is-Particle-Size.pdf
19. de Koning JP. Dry powder inhalation: technical and physiological aspects, prescribing and use. Dissertation, University of Groningen. http://dissertations.ub.rug.nl/faculties/science/2001/j.p.de.koning/
20. Al Habet S. NDA Application 21-868 Exubera Inhaled Insulin. Center For Drug Evaluation and Research, Clinical Pharmacology and Biopharmaceutics Review Final, 52-54. www.accessdata.fda.gov/drugsatfda-docs/nda/2006/021868s000- ClinPharmR.pdf
21. Hovione. Dry powder inhalation devices. TwinCaps. www.hovione.com/ inhalation/TwinCaps.pdf