The phytotoxin fusicoccin, a selective stabilizer of 14-3-3 interactions?

IUBMB Life

Volumn 65, Issue 6, 2013, Pages 513-517

  Camoni, Lorenzo ^a   Visconti, Sabina ^a   Aducci, Patrizia ^a  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

Author keywords

14 3 3 proteins; Drug development; Fusicoccin; Protein protein interaction

Indexed keywords

FUSICOCCIN; PROTEIN 14 3 3; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATASE;

ARTICLE; BINDING SITE; CHEMICAL STRUCTURE; DRUG RESEARCH; MOLECULAR DYNAMICS; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM;

14-3-3 PROTEINS; DRUG DEVELOPMENT; FUSICOCCIN; PROTEIN-PROTEIN INTERACTION;

14-3-3 PROTEINS; ANIMALS; ASCOMYCOTA; CHLOROPLAST PROTON-TRANSLOCATING ATPASES; DRUG DISCOVERY; GLYCOSIDES; HUMANS; MYCOTOXINS; PLANT DISEASES; PLANTS; PROTEIN BINDING; PROTEIN INTERACTION MAPS; PROTEIN STABILITY;

EID: 84881493413     PISSN: 15216543     EISSN: 15216551     Source Type: Journal    
DOI: 10.1002/iub.1167     Document Type: Article

References (33)

1. Fu, H., Subramanian, R. R., and Masters, S. C. (2000) 14-3-3 Proteins: structure, function, and regulation. Annu. Rev. Pharmacol. Toxicol.40, 617-647.
2. Aducci, P., Camoni, L., Marra, M., and Visconti, S. (2002) From cytosol to organelles: 14-3-3 proteins as multifunctional regulators of plant cell. IUBMB Life 53, 49-55.
3. Aitken, A. (2006) 14-3-3 Proteins: a historic overview. Semin. Cancer Biol. 16, 162-172.
4. Yaffe, M. B., Rittinger, K., Volinia, S., Caron, P. R., Aitken, A., et al. (1997) The structural basis for 14-3-3: phosphopeptide binding specificity. Cell 91, 961-971.
5. Coblitz, B., Wu, M., Shikano, S., and Li, M. (2006) C-Terminal binding: an expanded repertoire and function of 14-3-3 proteins. FEBS Lett. 580, 1531-1535.
6. Shikano, S., Coblitz, B., Sun, H., and Li, M. (2005) Genetic isolation of transport signals directing cell surface expression. Nat. Cell Biol. 7, 985-992.
7. Palmgren, M. G. (2001) Plant plasma membrane H+-ATPases: powerhouses for nutrient uptake. Annu. Rev. Plant Physiol. Plant Mol. Biol. 52, 817-845.
8. Ballio, A., Chain, E. B., De Leo, P., Erlanger, B. F., Mauri, M., et al. (1964) Fusicoccin: a new wilting toxin produced by Fusicoccum amygdali Del. Nature 203, 297.
9. Marrè, E. Fusicoccin: a tool in plant physiology. (1979)Annu. Rev. Plant Physiol. 30, 273-288.
10. Fuglsang, A. T., Visconti, S., Drumm, K., Jahn, T., Stensballe, A., et al. (1999) Binding of 14-3-3 protein to the plasma membrane H+-ATPase AHA2 involves the three C-Terminal residues Tyr(946)-Thr-Val and requires phosphorylation of Thr(947). J. Biol. Chem. 274, 36774-36780.
11. Fullone, M. R., Visconti, S., Marra, M., Fogliano, V., and Aducci, P. (1998) Fusicoccin effect on the in vitro interaction between plant 14-3-3 proteins and plasma membrane H+-ATPase. J. Biol. Chem. 273, 7698-7702.
12. Camoni, L., Iori, V., Marra, M., and Aducci, P. (2000) Phosphorylation-dependent interaction between plant plasma membrane H+-ATPase and 14-3-3 proteins. J. Biol. Chem. 275, 9919-9923.
13. Würtele, M., Jelich-Ottmann, C., Wittinghofer, A., and Oecking, C. (2003) Structural view of a fungal toxin acting on a 14-3-3 regulatory complex. EMBO J. 22, 987-994.
14. Meyer, C., Waldk̈otter, K., Sprenger, A., Schl̈osser, U. G., Luther, M., et al. (1993) Survey of the taxonomic and tissue distribution of microsomal binding sites for the nonhost selective fungal phytotoxin, fusicoccin. Z. Naturforsch. C. 48, 595-602.
15. Asahi, K., Honma, Y., Hazeki, K., Sassa, T., Kubohara, Y., et al. (1997) Cotylenin A, a plant-growth regulator, induces the differentiation in murine and human myeloid leukemia cells. Biochem. Biophys. Res. Commun. 238, 758-763.
16. Honma, Y., Kasukabe, T., Yamori, T., KatoN., and Sassa, T. (2005) Antitumor effect of cotylenin A plus interferonalpha: possible therapeutic agents against ovary carcinoma. Gynecol. Oncol. 99, 680-688.
17. De Vries-van Leeuwen, I. J., Kortekaas-Thijssen, C., Nzigou Mandouckou, J. A., Kas, S., Evidente, A., et al. (2010) Fusicoccin-A selectively induces apoptosis in tumor cells after interferon-Alpha priming. Cancer Lett. 293, 198-206.
18. Kasukabe, T., Okabe-Kado, J., and Honma, Y. (2008) Cotylenin A, a new differentiation inducer, and rapamycin cooperatively inhibit growth of cancer cells through induction of cyclin G2. Cancer Sci. 99, 1693-1698.
19. Kasukabe, T., Okabe-Kado, J., Haranosono, Y., Kato, N., and Honma, Y. (2013) Inhibition of rapamycin-induced Akt phosphorylation by cotylenin A correlates with their synergistic growth inhibition of cancer cells. Int. J. Oncol. 42, 767-775.
20. Bunney, T. D., de Boer, A. H., and Levin, M. (2003) Fusicoccin signaling reveals 14-3-3 protein function as a novel step in left-right patterning during amphibian embryogenesis. Development 130, 4847-4858.
21. Koumanov, F., Richardson, J. D., Murrow, B. A, and Holman, G. D. (2011) AS160 phosphotyrosine-binding domain constructs inhibit insulin-stimulated GLUT4 vesicle fusion with the plasma membrane. J. Biol. Chem. 286, 16574-16582.
22. Camoni, L., Di Lucente, C., Visconti, S., and Aducci, P. (2011) The phytotoxin fusicoccin promotes platelet aggregation via 14-3-3-glycoprotein Ib-IX-V interaction. Biochem. J. 436, 429-436.
23. Varga-Szabo, D., Pleines, I., and Nieswandt, B. (2008) Cell adhesion mechanisms in platelets. Arterioscler. Thromb. Vasc. Biol. 28, 403-412.
24. Dai, K., Bodnar, R., Berndt, M. C., and Du, X. (2005) A critical role for 14-3-3zeta protein in regulating the vWF binding function of platelet glycoprotein Ib-IX and its therapeutic implications. Blood 106, 1975-1981.
25. Ganguly, S., Weller, J. L., Ho, A., Chemineau, P., Malpaux, B., et al. (2005) Melatonin synthesis: 14-3-3-dependent activation and inhibition of arylalkylamine N-Acetyltransferase mediated by phosphoserine-205. Proc. Natl. Acad. Sci. USA 102, 1222-1227.
26. Sliva, D., Gu, M., Zhu, Y. X., Chen, J., Tsai, S., et al. (2000) 14-3-3zeta Interacts with the alpha-chain of human interleukin 9 receptor. Biochem. J. 345, 741-747.
27. O'Kelly, I., Butler, M. H., Zilberberg, N., and Goldstein, S. A. (2002) Forward transport. 14-3-3 Binding overcomes retention in endoplasmic reticulum by dibasic signals. Cell 111, 577-588.
28. Fujita, N., Sato, S., and Tsuruo, T. (2003) Phosphorylation of p27Kip1 at threonine 198 by p90 ribosomal protein S6 kinases promotes its binding to 14-3-3 and cytoplasmic localization. J. Biol. Chem. 278, 49254-49260.
29. Rong, J., Li, S., Sheng, G., Wu, M., Coblitz, B., et al. (2007) 14-3-3 Protein interacts with Huntingtin-Associated protein 1 and regulates its trafficking. J. Biol. Chem. 282, 4748-4756.
30. Okamoto, Y. and Shikano, S. (2011) Phosphorylation-dependent C-Terminal binding of 14-3-3 proteins promotes cell surface expression of HIV co-receptor GPR15. J. Biol. Chem. 286, 7171-7181.
31. Matta, A., Siu, K. M., and Ralhan, R. (2012) 14-3-3 Zeta as novel molecular target for cancer therapy. Expert Opin. Ther. Targets 16, 515-523.
32. Milroy, L. G., Brunsveld, L., and Ottmann, C. (2013) Stabilization and inhibition of protein-protein interactions: the 14-3-3 case study. ACS Chem. Biol. 8, 27-35.
33. Pettersen, E. F., Goddard, T. D., Huang, C. C., Couch, G. S., Greenblatt, D. M., et al. (2004) UCSF Chimera, a visualization system for exploratory research and analysis. J. Comput. Chem. 25, 1605-1612.