Multiple Reaction Monitoring (MRM) of plasma proteins in cardiovascular proteomics

Methods in Molecular Biology

Volumn 1000, Issue , 2013, Pages 191-199

  Dardé, Verónica M ^a   Barderas, Maria G ^a   Vivanco, Fernando ^b,c  

^a HOSPITAL NACIONAL DE PARAPLÉJICOS   (Spain)

^b UAM)   (Spain)

^c UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

Author keywords

Biomarker discovery; Candidate biomarker validation; Cardiovascular proteomics; Human plasma; Multiple reaction monitoring

Indexed keywords

APOLIPOPROTEIN A1; APOLIPOPROTEIN E; ARYLDIALKYLPHOSPHATASE; BIOLOGICAL MARKER; COMPLEMENT COMPONENT C3; FETUIN A; PLASMA PROTEIN; VITAMIN D BINDING PROTEIN; TRYPSIN;

ALKYLATION; AMINO ACID SEQUENCE; ANALYTIC METHOD; ARTICLE; CARDIOVASCULAR RISK; HUMAN; LIMIT OF QUANTITATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MULTIPLE REACTION MONITORING; PRIORITY JOURNAL; PROTEIN DENATURATION; PROTEOMICS; REDUCTION; SIGNAL NOISE RATIO; TANDEM MASS SPECTROMETRY; BLOOD; CARDIOVASCULAR DISEASE; CHEMISTRY; METABOLISM; PROCEDURES; PROTEIN DEGRADATION; METHODOLOGY;

ALKYLATION; BIOLOGICAL MARKERS; BLOOD PROTEINS; CARDIOVASCULAR DISEASES; HUMANS; PROTEIN DENATURATION; PROTEOLYSIS; PROTEOMICS; TRYPSIN;

EID: 84881492004     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-62703-405-0_14     Document Type: Article

References (21)

1. McGregor E, Dunn MJ (2003) Proteomics of heart disease. Hum Mol Genet 12(Spec No. 2):R135-R144
2. Van Eyk JE, Dunn MJ (2003) Proteomic and genomic analysis of cardiovascular disease. Wiley, Chichester
3. Mayr M, Mayr U, Chung YL, Yin X, Grif fi ths JR, Xu Q (2004) Vascular proteomics: Linking proteomic and metabolomic changes. Proteomics 4:3751-3761
4. Marian AJ, Nambi V (2004) Biomarkers of cardiac disease. Expert Rev Mol Diagn 4:805-820
5. Barderas MG, Tunon J, Darde VM, De la Cuesta F, Duran MC, Jiménez-Nácher JJ, Tarín N, López-Bescós L, Egido J, Vivanco F (2007) Circulating human monocytes in the acute coronary syndrome express a characteristic proteomic pro fi le. J Proteome Res 6:876-886
6. Darde VM, De la Cuesta F, Gil-Dones F, Alvarez-Llamas G, Barderas MG, Vivanco F (2010) Analysis of the plasma proteome associated with acute coronary syndrome: Does a permanent protein signature exist in the plasma of ACS patients J Proteome Res 9: 4420-4432
7. Gil-Dones F, Martin-Rojas T, Lopez- Almodovar LF, de la Cuesta F, Darde VM, Alvarez-Llamas G, Juarez-Tosina R, Barroso G, Vivanco F, Padial LR, Barderas MG (2010) Valvular aortic stenosis: A proteomic insight. Clin Med Insights Cardiol 4:1-7
8. Rifai N, Gillette MA, Carr SA (2006) Protein biomarker discovery and validation: The long and uncertain path to clinical utility. Nat Biotechnol 24:971-983
9. Perchalski R, Yost R, Wilder B (1982) Structural elucidation of drug metabolites by triple-quadrupole mass spectrometry. Anal Chem 54:1466-1471
10. Tiller PR, Cunniff J, Land AP, Schwartz J, Jardine I, Wake fi eld M, Lopez L, Newton JF, Burton RD, Folk BM, Buhrman DL, Price P, Wu D (1997) Drug quantitation on a benchtop liquid chromatography-tandem mass spectrometry system. J Chromatogr A 771: 119-125
11. Lee MS, Kerns EH (1999) LC/MS applications in drug development. Mass Spectrom Rev 18:187-279
12. Tai SS, Bunk DM, White ET, Welch MJ (2004) Development and evaluation of a reference measurement procedure for the determination of total 3,3,5-triiodothyronine in human serum using isotope-dilution liquid chromatography- tandem mass spectrometry. Anal Chem 76:5092-5096
13. Sannino A, Bolzoni L, Bandini M (2004) Application of liquid chromatography with electrospray tandem mass spectrometry to the determination of a new generation of pesticides in processed fruits and vegetables. J Chromatogr A 1036:161-169
14. Keshishian H, Addona T, Burgess M, Kuhn E, Carr SA (2007) Quantitative, multiplexed assays for low abundance proteins in plasma by targeted mass spectrometry and stable isotope dilution. Mol Cell Proteomics 6:2212-2229
15. Barr DB, Barr JR, Maggio VL, Whitehead RD Jr, Sadowski MA, Whyatt RM, Needham LL (2002) A multi-analyte method for the quanti fi cation of contemporary pesticides in human serum and plasma using high-resolution mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci 778:99-111
16. Keshishian H, Addona T, Burgess M, Mani DR, Shi X, Kuhn E, Sabatine MS, Gerszten RE, Carr SA (2009) Quanti fi cation of cardiovascular biomarkers in patient plasma by targeted mass spectrometry and stable isotope dilution. Mol Cell Proteomics 8:2339-2349
17. Kuhn E, Wu J, Karl J, Liao H, Zolg W, Guild B (2004) Quanti fi cation of C-reactive protein in the serum of patients with rheumatoid arthritis using multiple reaction monitoring mass spectrometry and 13 C labeled peptide standards. Proteomics 4:1175-1186
18. Gil-Dones F, Darde VM, Alonso-Orgaz S, Lopez-Almodovar LF, Mourino-Alvarez L, Padial LR, Vivanco F, Barderas MG (2012) Inside human aortic stenosis: A proteomic analysis of plasma. J Proteomics 75: 1639-1653
19. Hager JW (2002) A new linear ion trap mass spectrometer. Rapid Commun Mass Spectrom 16:512-526
20. Hopfgartner G, Varesio E, Tschappat V, Grivat C, Bourgogne E, Leuthold LA (2004) Triple quadrupole linear ion trap mass spectrometer for the analysis of small molecules and macromolecules. J Mass Spectrom 39:845-855
21. Unwin RD, Grif fi ths JR, Leverentz MK, Grallert A, Hagan IM, Whetton AD (2005) Multiple reaction monitoring to identify sites of protein phosphorylation with high sensitivity. Mol Cell Proteomics 4:1134-1144