-
1
-
-
34547297943
-
Influence of a performance-improvement initiative on quality of care for patients hospitalized with heart failure: Results of the Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure (OPTIMIZE-HF)
-
17646603 10.1001/archinte.167.14.1493
-
Fonarow GC, Abraham WT, Albert NM, et al. Influence of a performance-improvement initiative on quality of care for patients hospitalized with heart failure: results of the Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure (OPTIMIZE-HF). Arch Intern Med. 2007;167:1493-502.
-
(2007)
Arch Intern Med
, vol.167
, pp. 1493-1502
-
-
Fonarow, G.C.1
Abraham, W.T.2
Albert, N.M.3
-
2
-
-
34748819364
-
Influence of nonfatal hospitalization for heart failure on subsequent mortality in patients with chronic heart failure
-
17724259 10.1161/CIRCULATIONAHA.107.696906
-
Solomon SD, Dobson J, Pocock S, et al. Influence of nonfatal hospitalization for heart failure on subsequent mortality in patients with chronic heart failure. Circulation. 2007;116:1482-7.
-
(2007)
Circulation
, vol.116
, pp. 1482-1487
-
-
Solomon, S.D.1
Dobson, J.2
Pocock, S.3
-
3
-
-
59749099461
-
Acute heart failure syndromes
-
19215829 10.1016/j.jacc.2008.10.041
-
Gheorghiade M, Pang PS. Acute heart failure syndromes. J Am Coll Cardiol. 2009;53:557-73.
-
(2009)
J Am Coll Cardiol
, vol.53
, pp. 557-573
-
-
Gheorghiade, M.1
Pang, P.S.2
-
4
-
-
84864493727
-
ESC guidelines for the diagnosis and treatment of acute and chronic heart failure 2012: The Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2012 of the European Society of Cardiology. Developed in collaboration with the Heart Failure Association (HFA) of the ESC
-
22611136 10.1093/eurheartj/ehs104
-
McMurray JJ, Adamopoulos S, Anker SD, et al. ESC guidelines for the diagnosis and treatment of acute and chronic heart failure 2012: the Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2012 of the European Society of Cardiology. Developed in collaboration with the Heart Failure Association (HFA) of the ESC. Eur Heart J. 2012;33:1787-847.
-
(2012)
Eur Heart J
, vol.33
, pp. 1787-1847
-
-
McMurray, J.J.1
Adamopoulos, S.2
Anker, S.D.3
-
5
-
-
84857556332
-
Trends in death attributed to heart failure over the past two decades in Europe
-
22237388 10.1093/eurjhf/hfr182
-
Laribi S, Aouba A, Nikolaou M, et al. Trends in death attributed to heart failure over the past two decades in Europe. Eur J Heart Fail. 2012;14:234-9.
-
(2012)
Eur J Heart Fail
, vol.14
, pp. 234-239
-
-
Laribi, S.1
Aouba, A.2
Nikolaou, M.3
-
6
-
-
38949162580
-
Fluid overload in acute heart failure - Re-distribution and other mechanisms beyond fluid accumulation
-
18279771 10.1016/j.ejheart.2008.01.007
-
Cotter G, Metra M, Milo-Cotter O, Dittrich HC, Gheorghiade M. Fluid overload in acute heart failure - re-distribution and other mechanisms beyond fluid accumulation. Eur J Heart Fail. 2008;10:165-9.
-
(2008)
Eur J Heart Fail
, vol.10
, pp. 165-169
-
-
Cotter, G.1
Metra, M.2
Milo-Cotter, O.3
Dittrich, H.C.4
Gheorghiade, M.5
-
7
-
-
77957227912
-
Assessing and treating congestion in acute heart failure: A scientific statement from the acute heart failure committee of the Heart Failure Association of the European Society of Cardiology and endorsed by the European Society of Intensive Care Medicine
-
20354029 10.1093/eurjhf/hfq045
-
Gheorghiade M, Follath F, Ponikowski P, et al. Assessing and treating congestion in acute heart failure: a scientific statement from the acute heart failure committee of the Heart Failure Association of the European Society of Cardiology and endorsed by the European Society of Intensive Care Medicine. Eur J Heart Fail. 2010;12:423-33.
-
(2010)
Eur J Heart Fail
, vol.12
, pp. 423-433
-
-
Gheorghiade, M.1
Follath, F.2
Ponikowski, P.3
-
8
-
-
84866124993
-
The role of the kidney in heart failure
-
22888113 10.1093/eurheartj/ehs205 1:CAS:528:DC%2BC38XhtlWltrzJ
-
Metra M, Cotter G, Gheorghiade M, Dei Cas L, Voors AA. The role of the kidney in heart failure. Eur Heart J. 2012;33:2135-42.
-
(2012)
Eur Heart J
, vol.33
, pp. 2135-2142
-
-
Metra, M.1
Cotter, G.2
Gheorghiade, M.3
Dei Cas, L.4
Voors, A.A.5
-
9
-
-
84864271867
-
Dietary sodium intake in heart failure
-
22825409 10.1161/CIRCULATIONAHA.111.062430 1:CAS:528:DC%2BC38XhtVKqu7fE
-
Gupta D, Georgiopoulou VV, Kalogeropoulos AP, et al. Dietary sodium intake in heart failure. Circulation. 2012;126:479-85.
-
(2012)
Circulation
, vol.126
, pp. 479-485
-
-
Gupta, D.1
Georgiopoulou, V.V.2
Kalogeropoulos, A.P.3
-
10
-
-
79952260198
-
Diuretic strategies in patients with acute decompensated heart failure
-
21366472 10.1056/NEJMoa1005419 1:CAS:528:DC%2BC3MXivV2ktrg%3D
-
Felker MG, Lee KL, Bull DA, et al. Diuretic strategies in patients with acute decompensated heart failure. N Engl J Med. 2011;364:797-805.
-
(2011)
N Engl J Med
, vol.364
, pp. 797-805
-
-
Felker, M.G.1
Lee, K.L.2
Bull, D.A.3
-
11
-
-
79960090547
-
Effect of nesiritide in patients with acute decompensated heart failure
-
21732835 10.1056/NEJMoa1100171
-
O'Connor CM, Starling RC, Hernandez AF, et al. Effect of nesiritide in patients with acute decompensated heart failure. N Engl J Med. 2011;365:32-43.
-
(2011)
N Engl J Med
, vol.365
, pp. 32-43
-
-
O'Connor, C.M.1
Starling, R.C.2
Hernandez, A.F.3
-
12
-
-
0037181515
-
Short-term intravenous milrinone for acute exacerbation of chronic heart failure
-
10.1001/jama.287.12.1541 1:CAS:528:DC%2BD38XisVegt78%3D
-
Cuffe SM, Califf RM, Adams KF, et al. Short-term intravenous milrinone for acute exacerbation of chronic heart failure. J Am Med Assoc. 2002;287:1541-7.
-
(2002)
J Am Med Assoc
, vol.287
, pp. 1541-1547
-
-
Cuffe, S.M.1
Califf, R.M.2
Adams, K.F.3
-
13
-
-
29444454634
-
Clinical trials update from the American Heart Association: REPAIR-AMI, ASTAMI, JELIS, MEGA, REVIVE-II, SURVIVE, and PROACTIVE
-
16387630 10.1016/j.ejheart.2005.12.003 1:CAS:528:DC%2BD28XkvFWn
-
Cleland JGF, Freemantle N, Coletta AP, Clark AL. Clinical trials update from the American Heart Association: REPAIR-AMI, ASTAMI, JELIS, MEGA, REVIVE-II, SURVIVE, and PROACTIVE. Eur J Heart Fail. 2006;8:105-10.
-
(2006)
Eur J Heart Fail
, vol.8
, pp. 105-110
-
-
Cleland, J.G.F.1
Freemantle, N.2
Coletta, A.P.3
Clark, A.L.4
-
14
-
-
77957139942
-
Acute heart failure clinical drug development: From planning to proof of activity to phase III
-
20881385 10.1159/000318048
-
Cotter G, Voors AA, Davison BD. Acute heart failure clinical drug development: From planning to proof of activity to phase III. Cardiology. 2010;116:292-301.
-
(2010)
Cardiology
, vol.116
, pp. 292-301
-
-
Cotter, G.1
Voors, A.A.2
Davison, B.D.3
-
15
-
-
21344469500
-
In-hospital mortality in patients with acute decompensated heart failure requiring intravenous vasoactive medications. An analysis from the Acute Decompensated Heart Failure National Registry (ADHERE)
-
15992636 10.1016/j.jacc.2005.03.051
-
Abraham WT, Kirkwood AF, Fonarow GC, et al. In-hospital mortality in patients with acute decompensated heart failure requiring intravenous vasoactive medications. An analysis from the Acute Decompensated Heart Failure National Registry (ADHERE). J Am Coll Cardiol. 2005;46:57-64.
-
(2005)
J Am Coll Cardiol
, vol.46
, pp. 57-64
-
-
Abraham, W.T.1
Kirkwood, A.F.2
Fonarow, G.C.3
-
16
-
-
79955442898
-
A proposed model for initial assessment and management of acute heart failure syndromes
-
21521852 10.1001/jama.2011.515 1:CAS:528:DC%2BC3MXlsFSgtr4%3D
-
Gheorghiade M, Braunwald E. A proposed model for initial assessment and management of acute heart failure syndromes. JAMA. 2011;305:1702-3.
-
(2011)
JAMA
, vol.305
, pp. 1702-1703
-
-
Gheorghiade, M.1
Braunwald, E.2
-
17
-
-
84881476091
-
Clinical development of pharmacologic agents for acute heart failure syndromes: A proposal for a mechanistic translational phase
-
10.1016/j.ahj.2011.10.009 This article proposes insertion of a translational phase trial during clinical development of a pharmacologic agent to test the mechanistic hypothesis in a small, clinically " homogeneous" group of patients before proceeding to a phase II trial
-
•• Gheorghiade M, Pang P, O'Connor CM, et al. Clinical development of pharmacologic agents for acute heart failure syndromes: A proposal for a mechanistic translational phase. Am Heart J. 2012;163:149-55. This article proposes insertion of a translational phase trial during clinical development of a pharmacologic agent to test the mechanistic hypothesis in a small, clinically "homogeneous" group of patients before proceeding to a phase II trial.
-
(2012)
Am Heart J
, vol.163
, pp. 149-155
-
-
Gheorghiade, M.1
Pang, P.2
O'Connor, C.M.3
-
18
-
-
84867400768
-
Endothelial dysfunction, arterial stiffness and heart failure
-
22999723 10.1016/j.jacc.2011.11.082 1:CAS:528:DC%2BC38XhsFSls7%2FI This article focuses on the importance of endothelial function and vascular stiffness as targets for investigation of therapies in acute heart failure
-
• Marti CN, Gheorghiade M, Kalogeropoulos AP, et al. Endothelial dysfunction, arterial stiffness and heart failure. J Am Coll Cardiol. 2012;60:1455-69. This article focuses on the importance of endothelial function and vascular stiffness as targets for investigation of therapies in acute heart failure.
-
(2012)
J Am Coll Cardiol
, vol.60
, pp. 1455-1469
-
-
Marti, C.N.1
Gheorghiade, M.2
Kalogeropoulos, A.P.3
-
19
-
-
0032492071
-
Randomized trial of high-dose isosorbide dinitrate plus low-dose furosemide versus high-dose furosemide plus low-dose isosorbide dinitrate in severe pulmonary edema
-
9482291 10.1016/S0140-6736(97)08417-1 1:CAS:528:DyaK1cXhtV2qs74%3D
-
Cotter G, Metzkor E, Kaluski E, Faigenberg Z, et al. Randomized trial of high-dose isosorbide dinitrate plus low-dose furosemide versus high-dose furosemide plus low-dose isosorbide dinitrate in severe pulmonary edema. Lancet. 1998;351:389-93.
-
(1998)
Lancet
, vol.351
, pp. 389-393
-
-
Cotter, G.1
Metzkor, E.2
Kaluski, E.3
Faigenberg, Z.4
-
20
-
-
70449113183
-
Relaxin, a pleiotropic vasodilator for the treatment of heart failure
-
19101795 10.1007/s10741-008-9129-3 1:CAS:528:DC%2BD1MXhtlKju73O
-
Teichman SL, Unemori E, Dschietzig T, et al. Relaxin, a pleiotropic vasodilator for the treatment of heart failure. Heart Fail Rev. 2009;14:321-9.
-
(2009)
Heart Fail Rev
, vol.14
, pp. 321-329
-
-
Teichman, S.L.1
Unemori, E.2
Dschietzig, T.3
-
21
-
-
79961057515
-
Maternal vasodilation in pregnancy: The emerging role of relaxin
-
21613576 10.1152/ajpregu.00156.2011 1:CAS:528:DC%2BC3MXhtFSrtb%2FK
-
Conrad KP. Maternal vasodilation in pregnancy: The emerging role of relaxin. Am J Physiol Regul Integr Comp Physiol. 2011;301:R267-75.
-
(2011)
Am J Physiol Regul Integr Comp Physiol
, vol.301
, pp. 267-275
-
-
Conrad, K.P.1
-
22
-
-
77954623284
-
Relaxin: Review of biology and potential in treating heart failure
-
20424993 10.1007/s11897-010-0010-z 1:CAS:528:DC%2BC3cXht1CjsL3K This article provides an overview of relaxin biology and physiologic effects of relaxin in preclinical and clinical studies
-
• Teichman SL, Unemori E, Teerlink JR. Relaxin: Review of biology and potential in treating heart failure. Curr Heart Fail Rep. 2010;7:75-82. This article provides an overview of relaxin biology and physiologic effects of relaxin in preclinical and clinical studies.
-
(2010)
Curr Heart Fail Rep
, vol.7
, pp. 75-82
-
-
Teichman, S.L.1
Unemori, E.2
Teerlink, J.R.3
-
23
-
-
62649155715
-
Intravenous recombinant human relaxin in compensated heart failure: A safety, tolerability, and pharmacodynamic trial
-
19327619 10.1016/j.cardfail.2009.01.008 1:CAS:528:DC%2BD1MXjvVaht7c%3D
-
Dschietzig T, Teichman S, Unemori E, et al. Intravenous recombinant human relaxin in compensated heart failure: a safety, tolerability, and pharmacodynamic trial. J Card Fail. 2009;15:182-90.
-
(2009)
J Card Fail
, vol.15
, pp. 182-190
-
-
Dschietzig, T.1
Teichman, S.2
Unemori, E.3
-
24
-
-
65249190276
-
Relaxin for the treatment of patients with acute heart failure (pre-RELAX-AHF): A multicentre, randomized, placebo-controlled, parallel-group, dose-finding phase IIb study
-
19329178 10.1016/S0140-6736(09)60622-X 1:CAS:528:DC%2BD1MXltVCqtbk%3D
-
Teerlink JR, Metra M, Felker MG, et al. Relaxin for the treatment of patients with acute heart failure (pre-RELAX-AHF): A multicentre, randomized, placebo-controlled, parallel-group, dose-finding phase IIb study. Lancet. 2009;373:1429-39.
-
(2009)
Lancet
, vol.373
, pp. 1429-1439
-
-
Teerlink, J.R.1
Metra, M.2
Felker, M.G.3
-
25
-
-
84871986523
-
Serelaxin, recombinant human relaxin-2, for treatment of acute heart failure (RELAX-AHF): A randomized, placebo-controlled trial
-
23141816 10.1016/S0140-6736(12)61855-8 1:CAS:528:DC%2BC38Xhs1CjsL7E
-
Teerlink JR, Cotter G, Davison BA, et al. Serelaxin, recombinant human relaxin-2, for treatment of acute heart failure (RELAX-AHF): A randomized, placebo-controlled trial. Lancet. 2013;381:29-39.
-
(2013)
Lancet
, vol.381
, pp. 29-39
-
-
Teerlink, J.R.1
Cotter, G.2
Davison, B.A.3
-
26
-
-
84856140884
-
Effects of vasodilation in heart failure with preserved or reduced ejection fraction implications of distinct pathophysiologies on response to therapy
-
22281246 10.1016/j.jacc.2011.09.062 This study, which examined the effects of nitroprusside in distinct heart failure profiles, emphasizes the importance of developing targeted heart failure therapies
-
• Schwartzenberg S, Redfield MM, From AM, et al. Effects of vasodilation in heart failure with preserved or reduced ejection fraction implications of distinct pathophysiologies on response to therapy. J Am Coll Cardiol. 2012;59:442-51. This study, which examined the effects of nitroprusside in distinct heart failure profiles, emphasizes the importance of developing targeted heart failure therapies.
-
(2012)
J Am Coll Cardiol
, vol.59
, pp. 442-451
-
-
Schwartzenberg, S.1
Redfield, M.M.2
From, A.M.3
-
27
-
-
84871927704
-
Effect of serelaxin on cardiac, renal, and hepatic biomarkers in the relaxin in acute heart failure (RELAX-AHF) development program
-
23273292 10.1016/S0735-1097(13)60197-7 1:CAS:528:DC%2BC38XhvFWhsb3N
-
Metra M, Cotter G, Davison BA, et al. Effect of serelaxin on cardiac, renal, and hepatic biomarkers in the relaxin in acute heart failure (RELAX-AHF) development program. J Am Coll Cardiol. 2013;61:196-206.
-
(2013)
J Am Coll Cardiol
, vol.61
, pp. 196-206
-
-
Metra, M.1
Cotter, G.2
Davison, B.A.3
-
28
-
-
35848944656
-
Effects of tezosentan on symptoms and clinical outcomes in patients with acute heart failure: The VERITAS randomized controlled trials
-
Effects of tezosentan on symptoms and clinical outcomes in patients with acute heart failure: the VERITAS randomized controlled trials. JAMA 2007;298:2009-2019.
-
(2007)
JAMA
, vol.298
, pp. 2009-2019
-
-
-
29
-
-
84860390336
-
Influence of global region on outcomes in heart failure beta-blocker trials
-
21851879 10.1016/j.jacc.2011.03.057
-
O'Connor CM, Fiuzat M, Swedberg K, et al. Influence of global region on outcomes in heart failure beta-blocker trials. J Am Coll Cardiol. 2011;58:915-22.
-
(2011)
J Am Coll Cardiol
, vol.58
, pp. 915-922
-
-
O'Connor, C.M.1
Fiuzat, M.2
Swedberg, K.3
-
30
-
-
36849084209
-
The pathophysiology of acute heart failure-is it all about fluid accumulation?
-
18082483 10.1016/j.ahj.2006.02.038
-
Cotter G, Felker GM, Adams KF, et al. The pathophysiology of acute heart failure-is it all about fluid accumulation? Am Heart J. 2008;155:9-18.
-
(2008)
Am Heart J
, vol.155
, pp. 9-18
-
-
Cotter, G.1
Felker, G.M.2
Adams, K.F.3
-
31
-
-
38949158060
-
Acute heart failure as "acute endothelitis"-interaction of fluid overload and endothelial dysfunction
-
18279772 10.1016/j.ejheart.2007.12.007
-
Colombo PC, Onat D, Sabbah HN. Acute heart failure as "acute endothelitis"-interaction of fluid overload and endothelial dysfunction. Eur J Heart Fail. 2008;10:170-5.
-
(2008)
Eur J Heart Fail
, vol.10
, pp. 170-175
-
-
Colombo, P.C.1
Onat, D.2
Sabbah, H.N.3
-
32
-
-
77957139942
-
Acute heart failure clinical drug development: From planning to proof of activity to phase III
-
20881385 10.1159/000318048 This article compared multiple clinical AHF trials and demonstrated a high degree of heterogeneity in patient characteristics and outcome measures
-
• Cotter G, Voors AA, Davison BD. Acute heart failure clinical drug development: from planning to proof of activity to phase III. Cardiology. 2010;116:292-301. This article compared multiple clinical AHF trials and demonstrated a high degree of heterogeneity in patient characteristics and outcome measures.
-
(2010)
Cardiology
, vol.116
, pp. 292-301
-
-
Cotter, G.1
Voors, A.A.2
Davison, B.D.3
-
33
-
-
84864687000
-
Bayesian adaptive trial design in acute heart failure syndromes: Moving beyond the mega trial
-
22877798 10.1016/j.ahj.2011.11.023 This article proposes an AHF clinical trial design that is based on patient phenotypes
-
• Collins SP, Lindsell CJ, Pang PS, et al. Bayesian adaptive trial design in acute heart failure syndromes: moving beyond the mega trial. Am Heart J. 2012;164:138-45. This article proposes an AHF clinical trial design that is based on patient phenotypes.
-
(2012)
Am Heart J
, vol.164
, pp. 138-145
-
-
Collins, S.P.1
Lindsell, C.J.2
Pang, P.S.3
|