Hepatitis C virus infection of a thyroid cell line: Implications for pathogenesis of hepatitis C virus and thyroiditis

Thyroid

Volumn 23, Issue 7, 2013, Pages 863-870

  Blackard, Jason T ^a   Kong, Ling ^a   Huber, Amanda K ^b   Tomer, Yaron ^b,c  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD81 ANTIGEN; INTERLEUKIN 8; NONSTRUCTURAL PROTEIN 5A; PEGINTERFERON ALPHA; VIRUS RNA;

ARTICLE; AUTOIMMUNE THYROIDITIS; CELL LYSATE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DISEASE ASSOCIATION; HEPATITIS C; HEPATITIS C VIRUS; HUMAN; HUMAN CELL; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SUPERNATANT; THYROID CELL; UPREGULATION; VIRION; VIRUS PARTICLE; VIRUS REPLICATION; WESTERN BLOTTING;

ANTIGENS, CD81; AUTOIMMUNITY; CELL LINE; HEPACIVIRUS; HEPATITIS C; HUMANS; INTERFERON-ALPHA; INTERLEUKIN-8; SCAVENGER RECEPTORS, CLASS B; THYROID GLAND; THYROIDITIS; VIRAL CORE PROTEINS; VIRAL NONSTRUCTURAL PROTEINS; VIRUS REPLICATION;

EID: 84881434907     PISSN: 10507256     EISSN: 15579077     Source Type: Journal    
DOI: 10.1089/thy.2012.0507     Document Type: Article

References (52)

1. Alter M 2007 Epidemiology of hepatitis C virus infection. World J Gastroenterol 13:2436-2441
2. Blackard JT, Kemmer N, Sherman K 2006 Extrahepatic replication of HCV: Insights into clinical manifestations and biological consequences. Hepatology 44:15-22
3. Cacoub P, Poynard T, Ghillani P, Charlotte F, Olivi M, Piette JC, Opolon P 1999 Extrahepatic manifestations of chronic hepatitis C. MULTIVIRC Group. Multidepartment Virus C. Arthritis Rheum 42:2204-2212
4. Antonelli A, Ferri C, Pampana A, Fallahi P, Nesti C, Pasquini M, Marchi S, Ferrannini E 2004 Thyroid disorders in chronic hepatitis C. Am J Med 117:10-13
5. Bartolomé J, Rodríguez-Iñigo E, Quadros P, Vidal S, Pascual-Miguelañez I, Rodríguez-Montes JA, García-Sancho L, Carreño V 2008 Detection of hepatitis C virus in thyroid tissue from patients with chronic HCV infection. J Med Virol 80:1588-1594
6. Laskus T, Radkowski M, Wang L, Vargas H, Rakela J 1998 Search for hepatitis C virus extrahepatic replication sites in patients with acquired immunodeficiency syndrome: Specific detection of negative-strand viral RNA in various tissues. Hepatology 28:1398-1401
7. Andrade LJ, D'Oliveira A Jr, Silva CA, Nunes P, França LS, Malta AM, Paraná R 2011 A meta-analysis of patients with chronic hepatitis C treated with interferon-alpha to determine the risk of autoimmune thyroiditis. Acta Gastroenterol Latinoam 41:104-110
8. Tomer Y, Blackard JT, Akeno N 2007 Interferon alpha treatment and thyroid dysfunction. Endocrinol Metab Clin North Am 36:1051-1066
9. Akeno N, Blackard JT, Tomer Y 2008 HCV E2 protein binds directly to thyroid cells and induces IL-8 production: A new mechanism for HCV induced thyroid autoimmunity. J Autoimmun 31:339-344
10. Schönberger J, Bauer J, Spruss T, Weber G, Chahoud I, Eilles C, Grimm D 2000 Establishment and characterization of the follicular thyroid carcinoma cell line ML-1. J Mol Med 78:102-110
11. Cai Z, Zhang C, Chang KS, Jiang J, Ahn BC, Wakita T, Liang TJ, Luo G 2005 Robust production of infectious hepatitis C virus (HCV) from stably HCV cDNA-transfected human hepatoma cells. J Virol 79:13963-13973
12. Hiasa Y, Blackard JT, Lin W, Kamegaya Y, Horiike N, Onji M, Schmidt EV, Chung RT 2006 Cell-based models of sustained, interferon-sensitive hepatitis C virus genotype 1 replication. J Virol Methods 132:195-203
13. Meredith LW, Wilson GK, Fletcher NF, McKeating J. 2012 Hepatitis C virus entry: Beyond receptors. Rev Med Virol 22:182-193
14. Scarselli E, Ansuini H, Cerino R, Roccasecca RM, Acali S, Filocome E, Traboni C, Nicosia A, Cortese R, Vitelli A 2002 The human scavenger receptor class B type 1 is a novel candidate receptor for the hepatis C virus. EMBO J 21:5017-5025
15. Pateron D, Hartmann DJ, Duclos-Vallee JC, Jouanolle H, Beaugrand M 1992 Latent autoimmune thyroid disease in patients with chronic HCV hepatitis. J Hepatol 16:244-245
16. Quaranta JF, Tran A, Régnier D, Letestu R, Beusnel C, Fuzibet JG, Thiers V, Rampal P 1993 High prevalence of antibodies to hepatitis C virus (HCV) in patients with antithyroid autoantibodies. J Hepatol 18:136-138
17. Mohran ZY, Abdel Kader NA, Abdel Moez AT, Abbas A 2010 Subclinical autoimmune thyroid disorders in Egyptian patients with untreated chronic hepatitis C virus infection. J Egypt Soc Parasitol 40:45-56
18. Boadas J, Rodríguez-Espinosa J, Enríquez J MF, Martínez- Cerezo FJ, González P, Madoz P, Vilardell F 1995 Prevalence of thyroid autoantibodies is not increased in blood donors with hepatitis C virus infection. J Hepatol 22:611-615
19. Fernandez-Soto L, Gonzalez A, Escobar-Jimenez F, Vazquez R, Ocete E, Olea N, Salmeron J 1998 Increased risk of autoimmune thyroid disease in hepatitis C vs hepatitis B before, during, and after discontinuing interferon therapy. Arch Intern Med 158:1445-1448
20. Ganne-Carrie N, Medini A, Coderc E, Seror O, Christidis C, Grimbert S, Trinchet JC, Beaugrand M 2000 Latent autoimmune thyroiditis in untreated patients with HCV chronic hepatitis: A case-control study. J Autoimmun 14:189-193
21. Preziati D, La Rosa L, Covini G, Marcelli R, Rescalli S, Persani L, Del Ninno E, Meroni PL, Colombo M, Beck-Peccoz P 1995 Autoimmunity and thyroid function in patients with chronic active hepatitis treated with recombinant interferon alpha-2a. Eur J Endocrinol 132:587-593
22. Tomer Y, Villanueva R 2004 Hepatitis C and thyroid autoimmunity: Is there a link? Am J Med 117:60-61
23. Antonelli A, Ferri C, Fallahi P, Ferrari SM, Ghinoi A, Rotondi M, Ferrannini E 2006 Thyroid disorders in chronic hepatitis C virus infection. Thyroid 16:563-572
24. Carella C, Amato G, Biondi B, Rotondi M, Morisco F, Tuccillo C, Chiuchiolo N, Signoriello G, Caporaso N, Lombardi G 1995 Longitudinal study of antibodies against thyroid in patients undergoing interferon-alpha therapy for HCV chronic hepatitis. Horm Res 44:110-114
25. Carella C, Mazziotti G, Morisco F, Rotondi M, Cioffi M, Tuccillo C, Sorvillo F, Caporaso N, Amato G 2002 The addition of ribavirin to interferon-alpha therapy in patients with hepatitis C virus-related chronic hepatitis does not modify the thyroid autoantibody pattern but increases the risk of developing hypothyroidism. Eur J Endocrinol 146: 743-749
26. Marazuela M, García-Buey L, González-Fernández B, García-Monzón C, Arranz A, Borque MJ, Moreno-Otero R 1996 Thyroid autoimmune disorders in patients with chronic hepatitis C before and during interferon-alpha therapy. Clin Endocrinol (Oxf) 44:635-642
27. Roti E, Minelli R, Giuberti T, Marchelli S, Schianchi C, Gardini E, Salvi M, Fiaccadori F, Ugolotti G, Neri TM, Braverman LE 1996 Multiple changes in thyroid function in patients with chronic active HCV hepatitis treated with recombinant interferon-alpha. Am J Med 101:482-487
28. Watanabe U, Hashimoto E, Hisamitsu T, Obata H, Hayashi N 1994 The risk factor for development of thyroid disease during interferon-alpha therapy for chronic hepatitis C. Am J Gastroenterol 89:399-403
29. Tomer Y, Davies T 1993 Infection, thyroid disease and autoimmunity. Endocr Rev 14:107-120
30. Zeisel MB, Fofana I, Fafi-Kremer S, Baumert T 2011 Hepatitis C virus entry into hepatocytes: Molecular mechanisms and targets for antiviral therapies. J Hepatol 54:566-576
31. Ganesh BB, Bhattacharya P, Gopisetty A, Prabhakar B 2011 Role of cytokines in the pathogenesis and suppression of thyroid autoimmunity. J Interferon Cytokine Res 31:721-731
32. Fallahi P, Ferri C, Ferrari SM, Corrado A, Sansonno D, Antonelli A 2012 Cytokines and HCV-related disorders. Clin Develop Immunol 2012:468107
33. Fukuda R, Ishimura N, Ishihara S, Chowdhury A, Moriyama N, Nogami C, Miyake T, Niigaki M, Tokuda A, Satoh S, Sakai S, Akagi S, Watanabe M, Fukumoto S 1996 Intrahepatic expression of pro-inflammatory cytokine mRNAs and interferon efficacy in chronic hepatitis C. Liver 16:390-399
34. Shimoda K, Begum N, Shibuta K, Mora M, Bonkovsky H, Banner B, Barnard G 1998 Interleukin-8 and hIRH (SDF1-a/ PBSF) mRNA expression and histological activity index in patients with chronic hepatitis C. Hepatology 28:108-115
35. Polyak SJ, Khabar KS, Rezeiq M, Gretch D 2001 Elevated levels of interleukin-8 in serum are associated with hepatitis C infection and resistance to interferon therapy. J Virol 75:6209-6211
36. Polyak SJ, Khabar KS, Paschal DM, Ezelle HJ, Duverlie G, Barber GN, Levy DE, Mukaida N, Gretch DR 2001 Hepatitis C virus nonstructural 5A protein induces interleukin-8, leading to partial inhibition of the interferon-induced antiviral response. J Virol 75:6095-6106
37. Khabar KS, Al-Zoghaibi F, Al-Ahdal MN, Murayama T, Dhalla M, Mukaida N, Taha M, Al-Sedairy ST, Siddiqui Y, Kessie G, Matsushima K 1997 The alpha chemokine, interleukin 8, inhibits the antiviral action of interferon a. J Exp Med 186:1077-1085
38. Jia Y, Wei L, Jiang D, Wang J, Cong X, Fei R 2007 Antiviral action of interferon-alpha against hepatitis C virus replicon and its modulation by interferon-gamma and interleukin-8. J Gastroenterol Hepatol 22:1278-1285
39. Brass V, Moradpour D, Blum H 2007 Hepatitis C virus infection: In vivo and in vitro models. J Viral Hepat 14:64-67
40. Burlone ME, Budkowska A 2009 Hepatitis C virus cell entry: Role of lipoproteins and cellular receptors. J Gen Virol 90:1055-1070
41. Fournier C, Sureau C, Coste J, Ducos J, Pageaux G, Larrey D, Domergue J, Maurel P 1998 In vitro infection of adult normal human hepatocytes in primary culture by hepatitis C virus. J Gen Virol 79:2367-2374
42. Molina S, Castet V, Pichard-Garcia L, Wychowski C, Meurs E, Pascussi JM, Sureau C, Fabre JM, Sacunha A, Larrey D, Dubuisson J, Coste J, McKeating J, Maurel P, Fournier-Wirth C 2008 Serum-derived hepatitis C virus infection of primary human hepatocytes is tetraspanin CD81 dependent. J Virol 82:569-574
43. Rumin S, Berthillon P, Tanaka E, Kiyosawa K, Trabaud MA, Bizollon T, Gouillat C, Gripon P, Guguen-Guillouzo C, Inchauspe ́ G, Trépo C 1999 Dynamic analysis of hepatitis C virus replication and quasispecies selection in long-term cultures of adult human hepatocytes infected in vitro. J Gen Virol 80:3007-3018
44. Fukuhara T, Tani H, Shiokawa M, Goto Y, Abe T, Taketomi A, Shirabe K, Maehara Y, Matsuura Y 2011 Intracellular delivery of serum-derived hepatitis C virus. Microbes Infect 13:405-412
45. Sarhan MA, Chen AY, Russell RS, Michalak T 2012 Patientderived hepatitis C virus and JFH-1 clones differ in their ability to infect human hepatoma cells and lymphocytes. J Gen Virol 93:2399-2407
46. Pham T, MacParland S, Mulrooney P, Cooksley H, Naoumov N, Michalak T 2004 Hepatitis C virus persistence after spontaneous or treatment-induced resolution of hepatitis C. J Virol 78:5867-5874
47. Gong G, Lai L, Jiang Y, He Y, Su X 2003 HCV replication in PBMC and its influence on interferon therapy. World J Gastroenterol 9:291-294
48. Radkowski M, Gallegos-Orozco J, Jablonska J, Colby T, Walewska-Zielecka B, Kubicka J, Wilkinson J, Adair D, Rakela J, Laskus T 2005 Persistence of hepatitis C virus in patients successfully treated for chronic hepatitis C. Hepatology 41:106-114
49. Taliani G, Badolato M, Lecce R, Poliandri G, Bozza A, Duca F, Pasquazzi C, Clementi C, Furlan C, De Bac C 1995 Hepatitis C virus RNA in peripheral blood mononuclear cells: Relation with response to interferon treatment. J Med Virol 47:16-22
50. Saleh M, Tibbs C, Koskinas J, Pereira L, Bomford A, Portmann B, McFarlane I, Williams R 1994 Hepatic and extrahepatic hepatitis C virus replication in relation to response to interferon therapy. Hepatology 20:1399-1404
51. Watkins-Riedel T, Ferenci P, Steindl-Munda P, Gschwantler M, Mueller C, Woegerbauer M 2004 Early prediction of hepatitis C virus (HCV) infection relapse in nonresponders to primary interferon therapy by means of HCV RNA whole-blood analysis. Clin Infect Dis 39:1754- 1760
52. Schmidt W, Wu P, Brashear D, Klinzman D, Phillips M, LaBrecque D, Stapleton J 1998 Effect of interferon therapy on hepatitis C virus RNA in whole blood, plasma, and peripheral blood mononuclear cells. Hepatology 28:1110- 1116 Diseases Diseases Diseases