The small GTPase RhoA, but not Rac1, is essential for conditioned aversive memory formation through regulation of actin rearrangements in rat dorsal hippocampus

Acta Pharmacologica Sinica

Volumn 34, Issue 6, 2013, Pages 811-818

  Wang, Jun ^a   Wang, Yu Hua ^a,c   Hou, Yuan Yuan ^b   Xi, Tao ^a   Liu, Yao ^b   Liu, Jing Gen ^b  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^c NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

actin rearrangement; aversive memory; conditioned place aversion; dorsal hippocampus; morphine withdrawal; naloxone; NSC23766; Rac1; RhoA; Y27632

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; 4 AMINO 6 [2 [[4 (DIETHYLAMINO) 1 METHYLBUTYL]AMINO] 6 METHYL 4 PYRIMIDINYL] 2 METHYLQUINOLINE; F ACTIN; G ACTIN; NALOXONE; RAC1 PROTEIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN;

ACTIN POLYMERIZATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AVERSION; BRAIN SYNAPTOSOME; CONTROLLED STUDY; HIPPOCAMPUS; MALE; MEMORY; NONHUMAN; PROTEIN MODIFICATION; RAT; REGULATORY MECHANISM; WITHDRAWAL SYNDROME;

ACTINS; AMIDES; AMINOQUINOLINES; ANIMALS; AVOIDANCE LEARNING; HIPPOCAMPUS; MALE; MEMORY; MICROINJECTIONS; MORPHINE; NALOXONE; POLYMERIZATION; PYRIDINES; PYRIMIDINES; RAC1 GTP-BINDING PROTEIN; RATS; RATS, SPRAGUE-DAWLEY; RHOA GTP-BINDING PROTEIN; SUBSTANCE WITHDRAWAL SYNDROME;

EID: 84881407373     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2013.3     Document Type: Article

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