Neonatal neurobehavioral abnormalities and MRI brain injury in encephalopathic newborns treated with hypothermia

Early Human Development

Volumn 89, Issue 9, 2013, Pages 733-737

  Coleman, Maya B ^a   Glass, Penny ^a,b   Brown, Judy ^a   Kadom, Nadja ^a,b   Tsuchida, Tammy ^b   Scafidi, Joseph ^b   Chang, Taeun ^b   Vezina, Gilbert ^a,b   Massaro, An N ^a,b  

^a CHILDREN'S NATIONAL MEDICAL CENTER   (United States)

^b GEORGE WASHINGTON UNIVERSITY SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

Author keywords

Encephalopathy; Hypothermia; Magnetic resonance imaging; Neonate; Neurobehavioral assessment

Indexed keywords

APGAR SCORE; AROUSAL; ARTICLE; ATTENTION; BIRTH WEIGHT; BRAIN INJURY; CLINICAL ASSESSMENT; COGNITION; CONTROLLED STUDY; DISEASE SEVERITY; EXCITABILITY; FEMALE; FUNCTIONAL ASSESSMENT; GESTATIONAL AGE; HABITUATION; HUMAN; HYPOXIC ISCHEMIC ENCEPHALOPATHY; INDUCED HYPOTHERMIA; INJURY SEVERITY; MAJOR CLINICAL STUDY; MALE; MOVEMENT (PHYSIOLOGY); MUSCLE HYPERTONIA; MUSCLE HYPOTONIA; NEONATAL ENCEPHALOPATHY; NEUROIMAGING; NEWBORN; NEWBORN DISEASE; NEWBORN INTENSIVE CARE; NICU NETWORK NEUROBEHAVIORAL SCALE; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEAR MAGNETIC RESONANCE SCANNER; OBSERVATIONAL STUDY; PH; PROSPECTIVE STUDY; RATING SCALE; REFLEX; REGULATORY MECHANISM; SCORING SYSTEM; SEIZURE; STRESS; TOTAL MOTOR ABNORMALITY SCORE;

EID: 84881371630     PISSN: 03783782     EISSN: 18726232     Source Type: Journal    
DOI: 10.1016/j.earlhumdev.2013.05.006     Document Type: Article

References (28)

1. Dilenge M.E., Majnemer A., Shevell M.I. Long-term developmental outcome of asphyxiated term neonates. J Child Neurol 2001, 16:781-792.
2. Shankaran S., Woldt E., Koepke T., Bedard M.P., Nandyal R. Acute neonatal morbidity and long-term central nervous system sequelae of perinatal asphyxia in term infants. Early Hum Dev 1991, 25:135-148.
3. Gluckman P.D., Wyatt J.S., Azzopardi D., Ballard R., Edwards A.D., Ferriero D.M., et al. Selective head cooling with mild systemic hypothermia after neonatal encephalopathy: multicentre randomized trial. Lancet 2005, 365:663-670.
4. Shankaran S., Laptook A.R., Ehrenkranz R.A., Tyson J.E., McDonald S.A., Donovan E.F., et al. Whole-body hypothermia for neonates with hypoxic-ischemic encephalopathy. N Engl J Med 2005, 353:1574-1584.
5. Azzopardi D.V., Strohm B., Edwards A.D., et al. Moderate hypothermia to treat perinatal asphyxial encephalopathy. N Engl J Med 2009;361:1349-58. Erratum N Engl J Med 2010, 362:1056.
6. Jacobs S.E., Morley C.J., Inder T.E., Stewart M.J., Smith K.R., McNamara P.J., et al. Whole-body hypothermia for term and near-term newborns with hypoxic-ischemic encephalopathy: a randomized controlled trial. Arch Pediatr Adolesc Med 2011, 165:692-700.
7. Shankaran S., Barnes P.D., Hintz S.R., Laptook A.R., Zaterka-Baxter K.M., McDonald S.A., et al. Brain injury following trial of hypothermia for neonatal hypoxic-ischaemic encephalopathy. Arch Dis Child Fetal Neonatal Ed 2012, 97:F398-F404.
8. Rutherford M., Ramenghi L.A., Edwards A.D., Brocklehurst P., Halliday H., Levine M., et al. Assessment of brain tissue injury after moderate hypothermia in neonates with hypoxic-ischaemic encephalopathy: a nested substudy of a randomised controlled trial. Lancet Neurol 2010 Jan, 9(1):39-45.
9. Lester B.M., Tronick E.Z. History and description of the neonatal intensive care unit network neurobehavioral scale. Pediatrics 2004, 113:634-640.
10. Lester B.M., Tronick E.Z. Appendix3: summary score calculations. Pediatrics 2004, 113:695-699.
11. Tronick E.Z., Olson K., Rosenberg R., Bohne L., Lu J., Lester B.M. Normative neurobehavioral performance of healthy infants on the Neonatal Intensive Care Unit Network Neurobehavioral Scale. Pediatrics 2004, 113:676-678.
12. Lester B.M., Tronick E.Z., LaGasse L., Seifer R., Bauer C.R., Shankaran S., et al. Summary statistics of Neonatal Intensive Care Unit Network Neurobehavioral Scale scores from the Maternal Lifestyle Study: a quasi-normative sample. Pediatrics 2004, 113:668-675.
13. Lester B.M., Bagner D.M., Liu J., LaGasse L.L., Seifer R., Bauer C.R., et al. Infant neurobehavioral dysregulation: behavior problems in children with prenatal substance exposure. Pediatrics 2009, 124(5):1355-1362.
14. Liu J., Bann C., Lester B., Tronick E., Das A., Lagasse L., et al. Neonatal neurobehavior predicts medical and behavioral outcome. Pediatrics. 2010, 125:e90-e98.
15. Stephens B.E., Liu J., Lester B., Lagasse L., Shankaran S., Bada H., et al. Neurobehavioral assessment predicts motor outcome in preterm infants. J Pediatr. 2010, 156:366-371.
16. Barkovich A.J., Hajnal B.L., Vigneron D., Sola A., Partridge J.C., Allen F., et al. Prediction of neuromotor outcome in perinatal asphyxia: evaluation of MR scoring systems. AJNR 1998, 19:143-149.
17. Miller S.P., Ramaswamy V., Michelson D., Barkovich A.J., Holshouser B., Wycliffe N., et al. Patterns of brain injury in term neonatal encephalopathy. J Pediatr 2005, 146:453-460.
18. Massaro A.N., Chang T., Kadom N., Tsuchida T., Scafidi J., Glass P., et al. Biomarkers of brain injury in neonatal encephalopathy treated with hypothermia. J Pediatr 2012, 161:434-440.
19. Glass H.C., Nash K.B., Bonifacio S.L., Barkovich A.J., Ferriero D.M., Sullivan J.E., et al. Seizures and magnetic resonance imaging-detected brain injury in newborns cooled for hypoxic-ischemic encephalopathy. J Pediatr 2011, 159:731-735.
20. Boukydis C.F.Z., Bigsby R., Lester B.M. Clinical use of the Neonatal Intensive Care Unit Network Neurobehavioral Scale. Pediatrics 2004, 113:679-689. (Appendix 2:694).
21. Amiel-Tison C. Update of the Amiel-Tison neurologic assessment for the term neonate or at 40weeks corrected age. Pediatr Neurol 2002, 27:196-212.
22. Sarnat H.B., Sarnat M.S. Neonatal encephalopathy following fetal distress. Arch Neurol 1976, 33:696-705.
23. Gunn A.J., Wyatt J.S., Whitelaw A., Barks J., Azzopardi D., Ballard R., et al. Therapeutic hypothermia changes the prognostic value of clinical evaluation of neonatal encephalopathy. J Pediatr 2008, 152:55-58.
24. Shankaran S., Laptook A.R., Tyson J.E., Ehrenkranz R.A., Bann C.M., Das A., et al. Evolution of encephalopathy during whole-body hypothermia for neonatal hypoxic-ischemic encephalopathy. J Pediatr 2012, 160:567-572.
25. Ment L.R., Bada H.S., Barnes P., Grant P.E., Hirtz D., Papile L.A., et al. Practice parameter: neuroimaging of the neonate: report of the Quality Standards Subcommittee of the American Academy of Neurology and the Practice Committee of the Child Neurology Society. Neurology 2002, 58:1726-1738.
26. van Laerhoven H., de Haan T.R., Offringa M., Post B., van der Lee J.H. Prognostic tests in term neonates with hypoxic-ischemic encephalopathy: a systematic review. Pediatrics 2013, 131:88-98.
27. Lester B.M., Tronick E.Z. Using the NNNS. NICU Network Neurobehavioral Scale (NNNS) Manual 2004, 13-19. Paul H. Brookes Pub. Co., Baltimore, MD. B.M. Lester, E.Z. Tronick (Eds.).
28. Cohen J. Statistical power analysis for the behavioral sciences 1988, Lawrence Erlbaum Associates, Hillsdale, NJ. 2nd ed.