Identification of bio-active metabolites of gentiopicroside by UPLC/Q-TOF MS and NMR

Biomedical Chromatography

Volumn 27, Issue 9, 2013, Pages 1129-1136

  Zeng, Wenliang ^a,b   Han, Han ^a   Tao, Yanyan ^c   Yang, Li ^a   Wang, Zhengtao ^a   Chen, Kaixian ^a  

^a SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^b Shanghai Pharmaceutical Holding Co Ltd   (China)

^c SHUGUANG HOSPITAL AFFILIATED TO SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

Gentiopicroside; Hepatoprotective activity; Metabolites; UPLC Q TOF MS; glucosidase

Indexed keywords

BIOMOLECULES; LEAD COMPOUNDS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MEDICINE;

ACTIVE METABOLITES; BIO-ACTIVE; FRAGMENTATIONS PATTERN; GENTIOPICROSIDE; GLUCOSIDASE; HEPATOPROTECTIVE ACTIVITIES; MASS NMR; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY QUADRUPOLE TIME OF FLIGHT MASS SPECTROMETRIES; ULTRAPERFORMANCE LIQUID CHROMATOGRAPHY QUADRUPOLE TIME-OF-FLIGHT MASS SPECTROMETRIES; Β-GLUCOSIDASE;

METABOLITES;

BETA GLUCOSIDASE; DRUG METABOLITE; GENTIOPICRIN;

ARTICLE; CELL VIABILITY; CONTROLLED STUDY; DRUG TRANSFORMATION; ELECTROSPRAY MASS SPECTROMETRY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IN VITRO STUDY; ISOMERIZATION; LIVER CELL; LIVER PROTECTION; NUCLEAR MAGNETIC RESONANCE; OXIDATION REDUCTION POTENTIAL; TIME OF FLIGHT MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

GENTIANA SCABRA;

EID: 84881370442     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.2917     Document Type: Article

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