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Bioorganic and Medicinal Chemistry

Volumn 21, Issue 17, 2013, Pages 5076-5080

Cembrane diterpenoids from the soft coral Sarcophyton trocheliophorum Marenzeller as a new class of PTP1B inhibitors

(5) Liang, Lin Fu a Gao, Li Xin a Li, Jia a Taglialatela Scafati, Orazio b Guo, Yue Wei a

a SHANGHAI INSTITUTE OF MATERIA MEDICA (China)

b UNIVERSITY OF NAPLES FEDERICO II (Italy)

Author keywords

Cembrane; Marinde diterpenoids; PTP1B inhibition; Sarcophyton trocheliophorum

Indexed keywords

CEMBRANOID DERIVATIVE; PROTEIN TYROSINE PHOSPHATASE 1B; PROTEIN TYROSINE PHOSPHATASE 1B INHIBITOR; SARCOPHYTONOLIDE J; SARCOPHYTONOLIDE N; SARCOPHYTONOLIDE O; SARCOPHYTONOLIDE P; SARCOPHYTONOLIDE Q; SARCOPHYTONOLIDE R; UNCLASSIFIED DRUG;

ANTIDIABETIC ACTIVITY; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORAL; DRUG CYTOTOXICITY; DRUG HYDROLYSIS; DRUG ISOLATION; DRUG MECHANISM; DRUG OXIDATION; DRUG STRUCTURE; HUMAN; HUMAN TISSUE; IC 50; NONHUMAN; SARCOPHYTON TROCHELIOPHORUM; STRUCTURE ACTIVITY RELATION;

ALCYONACEA; SARCOPHYTON TROCHELIOPHORUM;

CEMBRANE; MARINDE DITERPENOIDS; PTP1B INHIBITION; SARCOPHYTON TROCHELIOPHORUM;

ANIMALS; ANTHOZOA; DITERPENES; ENZYME INHIBITORS; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR CONFORMATION; PROTEIN BINDING; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84881367433 PISSN: 09680896 EISSN: 14643391 Source Type: Journal
DOI: 10.1016/j.bmc.2013.06.043 Document Type: Article

Times cited : (59)

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