Identification of Trypanosome Proteins in Plasma from African Sleeping Sickness Patients Infected with T. b. rhodesiense

PLoS ONE

Volumn 8, Issue 8, 2013, Pages

  Eyford, Brett A ^a   Ahmad, Rushdy ^b   Enyaru, John C ^c   Carr, Steven A ^b   Pearson, Terry W ^a  

^a UNIVERSITY OF VICTORIA   (Canada)

^b BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^c MAKERERE UNIVERSITY   (Uganda)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE DEPENDENT CLP PROTEASE SUBUNIT; ADENOSINE TRIPHOSPHATE DEPENDENT PROTEINASE; AMINOPEPTIDASE; AMINOPEPTIDASE NPEPL1; CALMODULIN; CALPAIN LIKE CYSTEINE PEPTIDASE; CARBOXYPEPTIDASE; CELL CYCLE PROTEIN; CELL DIVISION CYCLE PROTEIN 16; HEAT SHOCK PROTEIN 70; OLIGOPEPTIDASE A; PEPTIDASE; PEPTIDES AND PROTEINS; PEPTIDYLPROLYL ISOMERASE; POLYUBIQUITIN; PROLYL ENDOPEPTIDASE; PROTEIN DNAJ; PROTOZOAL PROTEIN; RETROTRANSPOSON HOT SPOT PROTEIN; RPT6 PROTEASOME REGULATORY ADENOSINE TRIPHOSPHATASE SUBUNIT 6; SERINE CARBOXYPEPTIDASE; SERINE CARBOXYPEPTIDASE III PRECURSOR; TRANSALDOLASE; TRIOSEPHOSPHATE ISOMERASE; TRYPSIN; UBIQUITIN ACTIVATING ENZYME E1; UBIQUITIN ACTIVATING ENZYME E2; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

AFRICAN TRYPANOSOMIASIS; ANTIGEN DETECTION; ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; IMMUNODEPLETION; IMMUNOLOGICAL PROCEDURES; LIQUID CHROMATOGRAPHY; NONHUMAN; NUCLEOTIDE SEQUENCE; PATIENT MONITORING; PROTEIN BLOOD LEVEL; PROTEIN DETERMINATION; PROTEIN FUNCTION; PROTEOMICS; STAGING; TANDEM MASS SPECTROMETRY; TRYPANOSOMA BRUCEI; TRYPANOSOMA RHODESIENSE;

CHILD; CHROMATOGRAPHY, LIQUID; FEMALE; HUMANS; MALE; MIDDLE AGED; PROTEINS; PROTEOMICS; TANDEM MASS SPECTROMETRY; TRYPANOSOMA BRUCEI RHODESIENSE; TRYPANOSOMIASIS, AFRICAN;

EID: 84881357402     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0071463     Document Type: Article

References (38)

1. Magnus E, Vervoort T, Van Meirvenne N, (1978) A card-agglutination test with stained trypanosomes (C.A.T.T.) for the serological diagnosis of T. b. gambiense trypanosomiasis. Annales de la Société Belge de Médecine Tropicale 58: 169-176.
2. Lejon V, Büscher P, Magnus E, Moons A, Wouters I, et al. (1998) A semi-quantitative ELISA for detection of Trypanosoma brucei gambiense specific antibodies in serum and cerebrospinal fluid of sleeping sickness patients. Acta Tropica 69: 151-164.
3. Njiru ZK, Mikosza AS, Armstrong T, Enyaru JC, Ndung'u JM, et al. (2008) Loop-mediated isothermal amplification (LAMP) method for rapid detection of Trypanosoma brucei rhodesiense. PLoS Neglected Tropical Diseases 2: e147.
4. Njiru ZK, Traub R, Ouma JO, Enyaru JC, Matovu E, (2011) Detection of Group 1 Trypanosoma brucei gambiense by Loop-Mediated Isothermal Amplification. Journal of Clinical Microbiology 49: 1530-1536.
5. Chappuis F, Loutan L, Simarro P, Lejon V, Buscher P, (2005) Options for field diagnosis of human african trypanosomiasis. Clinical Microbiology Reviews 18: 133-146.
6. Programme Against African Trypanosomosis (2007) Tsetse and Trypanosomiasis Information Bulletin, Volume 30, Part 2.
7. Masake RA, Nantulya VM, (1991) Sensitivity of an antigen detection enzyme immunoassay for diagnosis of Trypanosoma congolense infections in goats and cattle. Journal of Parasitology 77: 231-236.
8. Nantulya VM, Lindqvist KJ, Stevenson P, Mwangi EK, (1992) Application of a monoclonal antibody-based antigen detection enzyme-linked immunosorbent assay (antigen ELISA) for field diagnosis of bovine trypanosomiasis at Nguruman, Kenya. Annals of Tropical Medicine and Parasitolology 86: 225-230.
9. Kashiwazaki Y, Snowden K, Smith DH, Hommel M, (1994) A multiple antigen detection dipstick colloidal dye immunoassay for the field diagnosis of trypanosome infections in cattle. Veterinary Parasitology 55: 57-69.
10. Liu MK, Pearson TW, (1987) Detection of circulating trypanosomal antigens by double antibody ELISA using antibodies to procyclic trypanosomes. Parasitology 95: 277-290.
11. Liu MK, Pearson TW, Sayer PD, Gould SS, Waitumbi JN, et al. (1988) Serodiagnosis of African sleeping sickness in vervet monkeys by detection of parasite antigens. Acta Tropica 45: 321-320.
12. Liu MK, Cattand P, Gardiner IC, Pearson TW, (1989) Immunodiagnosis of sleeping sickness due to Trypanosoma brucei gambiense by detection of antiprocyclic antibodies and trypanosome antigens in patients' sera. Acta Tropica 46: 257-266.
13. Liu MK, Wellde BT, Pearson TW (1989) Trypanosoma brucei rhodesiense: Immunodiagnosis of African sleeping sickness by detection of antigen and antibodies in documented sera from Lambwe Valley, Western Kenya. M. Liu, PhD thesis: University of Victoria.
14. Nantulya VM, (1989) An antigen detection enzyme immunoassay for the diagnosis of rhodesiense sleeping sickness. Parasite Immunology 11: 69-75.
15. Rae PF, Luckins AG, (1984) Detection of circulating trypanosomal antigens by enzyme immunoassay. Annals of Tropical Medicine and Parasitology 78: 587-596.
16. Manful T, Mulindwa J, Frank FM, Clayton CE, Matovu E, (2010) A search for Trypanosoma brucei rhodesiense diagnostic antigens by proteomic screening and targeted cloning. PLoS ONE 5: e9630.
17. Hutchinson OC, Webb H, Picozzi K, Welburn S, Carrington M, (2004) Candidate protein selection for diagnostic markers of African trypanosomiasis. Trends in Parasitology 20: 519-523.
18. Anderson NL, Anderson NG, (2002) The Human Plasma Proteome: history, character, and diagnostic prospects. Molecular & Cellular Proteomics 1: 845-867.
19. Hortin GL, Sviridov D, Anderson NL, (2008) High-Abundance Polypeptides of the Human Plasma Proteome Comprising the Top 4 Logs of Polypeptide Abundance. Clinical Chemistry 54: 1608-1616.
20. Fish WR, Muriuki CW, Muthiani AM, Grab DJ, Lonsdale-Eccles JD, (1989) Disulfide bond involvement in the maintenance of the cryptic nature of the cross-reacting determinant of metacyclic forms of Trypanosoma congolense. Biochemistry 28: 5415-5421.
21. Cross GA, Manning JC, (1973) Cultivation of Trypanosoma brucei spp. in semi-defined and defined media. Parasitology 67: 315-331.
22. Anderson NL, Parish NM, Richardson JP, Pearson TW, (1985) Comparison of African trypanosomes of different antigenic phenotypes, subspecies and life cycle stages by two-dimensional gel electrophoresis. Molecular and Biochemical Parasitology 16: 299-314.
23. Brun R, Schönenberger M, (1979) Cultivation and in vitro cloning or procyclic culture forms of Trypanosoma brucei in a semi-defined medium. Acta Tropica 36: 289-292.
24. Tolson DL, Turco SJ, Beecroft RP, Pearson TW, (1989) The immunochemical structure and surface arrangement of Leishmania donovani lipophosphoglycan determined using monoclonal antibodies. Molecular and Biochemical Parasitology 35: 109-118.
25. Woo PTK, (1970) The haematocrit centrifuge technique for the diagnosis of African trypanosomiasis. Atca Tropica 27: 384-386.
26. Patel BB, Barrero CA, Braverman A, Kim PD, Jones KA, et al. (2012) Assessment of Two Immunodepletion Methods: Off-Target Effects and Variations in Immunodepletion Efficiency May Confound Plasma Proteomics. Journal of Proteome Research 11: 5947-5958.
27. Elias JE, Gibbons FD, King OD, Roth FP, Gygi SP, (2004) Intensity-based protein identification by machine learning from a library of tandem mass spectra. Nature Biotechnology 22: 214-219.
28. Nesvizhskii AI, Aebersold R, (2005) Interpretation of Shotgun Proteomic Data. Molecular & Cellular Proteomics 4: 1419-1440.
29. Kuepfer I, Hhary EP, Allan M, Edielu A, Burri C, et al. (2011) Clinical Presentation of T. b. rhodesiense Sleeping Sickness in Second Stage Patients from Tanzania and Uganda. PLoS Neglected Tropical Diseases 5: e968.
30. Huang H, Mackeen M, Cook M, Oriero E, Locke E, et al. (2012) Proteomic identification of host and parasite biomarkers in saliva from patients with uncomplicated Plasmodium falciparum malaria. Malaria Journal 11: 178.
31. Murray CK, Bennett JW, (2009) Rapid Diagnosis of Malaria. Interdisciplinary Perspectives on Infectious Diseases. 2009: 415953.
32. Grébaut P, Chuchana P, Brizard JP, Demettre E, Seveno M, et al. (2009) Identification of total and differentially expressed excreted-secreted proteins from Trypanosoma congolense strains exhibiting different virulence and pathogenicity. Int J Parasitol 39: 1137-1150.
33. Authie E, (1994) Trypanosomiasis and trypanotolerance in cattle: a role for congopain? Parasitology Today 10: 360-364.
34. Anderson NL, Anderson NG, Haines LR, Hardie DB, Olafson RW, et al. (2004) Mass Spectrometric Quantitation of Peptides and Proteins Using Stable Isotope Standards and Capture by Anti-Peptide Antibodies (SISCAPA). Journal of Proteome Research 3: 235-244.
35. Eyford BA, Sakurai T, Smith D, Loveless B, Hertz-Fowler C, et al. (2011) Differential protein expression throughout the life cycle of Trypanosoma congolense, a major parasite of cattle in Africa. Molecular and Biochemical Parasitology 177: 116-125.
36. Clamp M, Fry B, Kamal M, Xie X, Cuff J, et al. (2007) Distinguishing protein-coding and noncoding genes in the human genome. Proceedings of the National Academy of Sciences 104: 19428-19433.
37. Agranoff D, Stich A, Abel P, Krishna S, (2005) Proteomic fingerprinting for the diagnosis of human African trypanosomiasis. Trends in Parasitology 21: 154-157.
38. Papadopoulos MC, Abel PM, Agranoff D, Stich A, Tarelli E, et al. (2004) A novel and accurate diagnostic test for human African trypanosomiasis. The Lancet 363: 1358-1363.