SLC1A2 Variant Is Associated with Essential Tremor in Taiwanese Population

PLoS ONE

Volumn 8, Issue 8, 2013, Pages

  Yu, Shao wen ^a   Chen, Chiung Mei ^a   Chen, Yi Chun ^a   Chang, Chia Wen ^a   Chang, Hong Shiu ^a   Lyu, Rong Kuo ^a   Ro, Long Sun ^a   Wu, Yih Ru ^a  

^a CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

EXCITATORY AMINO ACID TRANSPORTER 2;

ADULT; ALLELE; ARTICLE; ASIAN; CASE CONTROL STUDY; CHINESE; COHORT ANALYSIS; CONTROLLED STUDY; ESSENTIAL TREMOR; ETHNIC DIFFERENCE; FEMALE; GENE FREQUENCY; GENE REPLICATION; GENETIC ASSOCIATION; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; HUMAN; MAJOR CLINICAL STUDY; MALE; SINGLE NUCLEOTIDE POLYMORPHISM; SLC1A2 GENE; TAIWAN;

ADULT; AGED; ESSENTIAL TREMOR; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; GLUTAMATE PLASMA MEMBRANE TRANSPORT PROTEINS; HUMANS; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; TAIWAN;

EID: 84881341410     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0071919     Document Type: Article

References (20)

1. Louis ED, (2005) Essential tremor. Lancet Neurol 4: 100-110. doi:10.1016/S1474-4422(05)00991-9. PubMed: 15664542.
2. Deuschl G, Bain P, Brin M, (1998) Consensus statement of the Movement Disorder Society on Tremor. Ad Hoc Scientific Committee Mov Disord 13 (Suppl 3):: 2-23.
3. Rowland Lewis P (2010) Merritt's Neurology. Timothy A, editor. New York.
4. Deng H, Le W, Jankovic J, (2007) Genetics of essential tremor. Brain 130: 1456-1464. doi:10.1093/brain/awm018. PubMed: 17353225.
5. Louis ED, Ottman R, (2006) Study of possible factors associated with age of onset in essential tremor. Mov Disord 21: 1980-1986. doi:10.1002/mds.21102. PubMed: 16991147.
6. Stefansson H, Steinberg S, Petursson H, Gustafsson O, Gudjonsdottir IH, et al. (2009) Variant in the sequence of the LINGO1 gene confers risk of essential tremor. Nat Genet 41: 277-279. doi:10.1038/ng.299. PubMed: 19182806.
7. Tanner CM, Goldman SM, Lyons KE, Aston DA, Tetrud JW, et al. (2001) Essential tremor in twins: an assessment of genetic vs environmental determinants of etiology. Neurology 57: 1389-1391. doi:10.1212/WNL.57.8.1389. PubMed: 11673577.
8. Lorenz D, Frederiksen H, Moises H, Kopper F, Deuschl G, et al. (2004) High concordance for essential tremor in monozygotic twins of old age. Neurology 62: 208-211. doi:10.1212/01.WNL.0000103236.26934.41. PubMed: 14745055.
9. Gulcher JR, Jónsson P, Kong A, Kristjánsson K, Frigge ML, et al. (1997) Mapping of a familial essential tremor gene, FET1, to chromosome 3q13. Nat Genet 17: 84-87. doi:10.1038/ng0997-84. PubMed: 9288103.
10. Higgins JJ, Pho LT, Nee LE, (1997) A gene (ETM) for essential tremor maps to chromosome 2p22-p25. Mov Disord 12: 859-864. doi:10.1002/mds.870120605. PubMed: 9399207.
11. Shatunov A, Sambuughin N, Jankovic J, Elble R, Lee HS, et al. (2006) Genomewide scans in North American families reveal genetic linkage of essential tremor to a region on chromosome 6p23. Brain 129: 2318-2331. doi:10.1093/brain/awl120. PubMed: 16702189.
12. Tan EK, Schapira AH, (2008) Hunting for genes in essential tremor. Eur J Neurol 15: 889-890. doi:10.1111/j.1468-1331.2008.02226.x. PubMed: 18796073.
13. Aridon P, Ragonese P, De Fusco M, Salemi G, Casari G, et al. (2008) Further evidence of genetic heterogeneity in familial essential tremor. Parkinsonism Relat Disord 14: 15-18. doi:10.1016/S1353-8020(08)70117-2. PubMed: 17703985.
14. Thier S, Lorenz D, Nothnagel M, Stevanin G, Dürr A, et al. (2010) LINGO1 polymorphisms are associated with essential tremor in Europeans. Mov Disord 25: 717-723. doi:10.1002/mds.22887. PubMed: 20310002.
15. Jiménez-Jiménez FJ, García-Martín E, Lorenzo-Betancor O, Pastor P, Alonso-Navarro H, et al. (2012) LINGO1 and risk for essential tremor: results of a meta-analysis of rs9652490 and rs11856808. J Neurol Sci 317: 52-57. doi:10.1016/j.jns.2012.02.030. PubMed: 22425540.
16. Deng H, Gu S, Jankovic J, (2012) LINGO1 variants in essential tremor and Parkinson's disease. Acta Neurol Scand 125: 1-7. doi:10.1111/j.1600-0404.2011.01567.x. PubMed: 21470193.
17. Thier S, Lorenz D, Nothnagel M, Poremba C, Papengut F, et al. (2012) Polymorphisms in the glial glutamate transporter SLC1A2 are associated with essential tremor. Neurology 79: 243-248. doi:10.1212/WNL.0b013e31825fdeed. PubMed: 22764253.
18. Tan EK, Foo JN, Tan L, Au WL, Prakash KM, et al. (2013) SLC1A2 variant associated with essential tremor but not Parkinson disease in Chinese subjects. Neurology 80(17):: 1618-1619. doi:10.1212/WNL.0b013e31828f1903. PubMed: 23596072.
19. Elble RJ, Deuschl G, (2009) An update on essential tremor. Curr Neurol Neurosci Rep 9: 273-277. doi:10.1007/s11910-009-0041-6. PubMed: 19515278.
20. Deuschl G, Bergman H, (2002) Pathophysiology of nonparkinsonian tremors. Mov Disord 17 (Suppl 3):: S41-S48. doi:10.1002/mds.10141. PubMed: 11948754.