Three-arm noninferiority trials with a prespecified margin for inference of the difference in the proportions of binary endpoints

Journal of Biopharmaceutical Statistics

Volumn 23, Issue 4, 2013, Pages 774-789

  Hida, Eisuke ^a   Tango, Toshiro ^b  

^a NATIONAL INSTITUTE OF PUBLIC HEALTH   (Japan)

^b Center for Medical Statistics   (Japan)

Author keywords

Assay sensitivity; Binary endpoint; Optimal allocation; Prespecified noninferiority margin; Three arm noninferiority

Indexed keywords

DULOXETINE; PAROXETINE; PLACEBO;

ARTICLE; CLINICAL TRIAL (TOPIC); COMPARATIVE STUDY; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; EFFECT SIZE; EXPERIMENTAL THERAPY; HAMILTON SCALE; HUMAN; MAJOR CLINICAL STUDY; MAJOR DEPRESSION; MONTE CARLO METHOD; MULTICENTER STUDY; PARALLEL DESIGN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; REMISSION; SAMPLE SIZE; STUDY DESIGN; VALIDATION PROCESS;

ANTIDEPRESSIVE AGENTS; CONFIDENCE INTERVALS; DATA INTERPRETATION, STATISTICAL; DEPRESSIVE DISORDER, MAJOR; DOUBLE-BLIND METHOD; ENDPOINT DETERMINATION; HUMANS; MODELS, STATISTICAL; MONTE CARLO METHOD; PLACEBOS; RANDOMIZED CONTROLLED TRIALS AS TOPIC; RESEARCH DESIGN; SAMPLE SIZE; THIOPHENES; TREATMENT OUTCOME;

EID: 84881302277     PISSN: 10543406     EISSN: 15205711     Source Type: Journal    
DOI: 10.1080/10543406.2013.789893     Document Type: Article

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