On the three-arm non-inferiority trial including a placebo with a prespecified margin

Statistics in Medicine

Volumn 30, Issue 3, 2011, Pages 224-231

  Hida, Eisuke ^a   Tango, Toshiro ^a  

^a NATIONAL INSTITUTE OF PUBLIC HEALTH   (Japan)

Author keywords

Assay sensitivity; Bivariate normal distribution; Non inferiority trial; Optimal allocation; Prespecified non inferiority margin; Three arm design

Indexed keywords

PLACEBO;

ARTICLE; CLINICAL TRIAL (TOPIC); EFFECT SIZE; MAJOR DEPRESSION; NORMAL DISTRIBUTION; RANDOMIZED CONTROLLED TRIAL (TOPIC); SAMPLE SIZE; STATISTICAL MODEL; VARIANCE;

ALGORITHMS; ANTIDEPRESSIVE AGENTS; COMPUTER SIMULATION; CONFIDENCE INTERVALS; DEPRESSIVE DISORDER, MAJOR; DOUBLE-BLIND METHOD; HUMANS; MODELS, STATISTICAL; MONTE CARLO METHOD; MULTICENTER STUDIES AS TOPIC; NORMAL DISTRIBUTION; PAROXETINE; PLACEBOS; RANDOMIZED CONTROLLED TRIALS AS TOPIC; SAMPLE SIZE; THIOPHENES; TREATMENT OUTCOME;

EID: 78650942468     PISSN: 02776715     EISSN: 10970258     Source Type: Journal    
DOI: 10.1002/sim.4099     Document Type: Article

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