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Volumn 29, Issue 1, 2013, Pages 11-15

Gut dysfunction in the critically ill - Mechanisms and clinical implications

Author keywords

[No Author keywords available]

Indexed keywords

PROBIOTIC AGENT;

EID: 84881273789     PISSN: 15628264     EISSN: None     Source Type: Journal    
DOI: 10.7196/SAJCC.148     Document Type: Article
Times cited : (18)

References (44)
  • 1
    • 4944259806 scopus 로고    scopus 로고
    • Does enteral nutrition compared to parenteral nutrition result in better outcomes in critically ill adult patients? A systematic review of the literature
    • Gramlich L, Kichian K, Pinilla J, et al. Does enteral nutrition compared to parenteral nutrition result in better outcomes in critically ill adult patients? A systematic review of the literature. Nutrition 2004;20(10): 843-848. [http://dx.doi.org/10.1016/j.nut.2004.06.003]
    • (2004) Nutrition , vol.20 , Issue.10 , pp. 843-848
    • Gramlich, L.1    Kichian, K.2    Pinilla, J.3
  • 3
    • 60349104314 scopus 로고    scopus 로고
    • Gastrointestinal symptoms in intensive care patients
    • Reintam A, Parm P, Kitus R, et al. Gastrointestinal symptoms in intensive care patients. Acta Anaesthesiol Scand 2009;53: 318-324. [http://dx.doi.org/10. 1111/j.1399-6576.2008.01860.x]
    • (2009) Acta Anaesthesiol Scand , vol.53 , pp. 318-324
    • Reintam, A.1    Parm, P.2    Kitus, R.3
  • 4
    • 0032876087 scopus 로고    scopus 로고
    • Enteral nutrition-related gastrointestinal complications in critically ill patients: A multicenter study: The Nutritional and Metabolic Working Group of the Spanish Society of Intensive Care Medicine and Coronary Units
    • Montejo JC. Enteral nutrition-related gastrointestinal complications in critically ill patients: A multicenter study: The Nutritional and Metabolic Working Group of the Spanish Society of Intensive Care Medicine and Coronary Units. Crit Care Med 1999;27: 1447-1453. [http://dx.doi. org/10.1097/00003246- 199908000-00006]
    • (1999) Crit Care Med , vol.27 , pp. 1447-1453
    • Montejo, J.C.1
  • 5
    • 0036218528 scopus 로고    scopus 로고
    • Multicenter, prospective, randomized, single-blind study comparing the efficacy and gastrointestinal complications of early jejunal feeding with early gastric feeding in critically ill patients
    • for the Nutritional and Metabolic Working Group of the Spanish Society of Intensive Care Medicine and Coronary Units
    • Montejo JC, Grau T, Acosta J, et al. for the Nutritional and Metabolic Working Group of the Spanish Society of Intensive Care Medicine and Coronary Units. Multicenter, prospective, randomized, single-blind study comparing the efficacy and gastrointestinal complications of early jejunal feeding with early gastric feeding in critically ill patients. Crit Care Med 2002; 30(4): 796-800. [http://dx.doi.org/10.1097/00003246-200204000-00013]
    • (2002) Crit Care Med , vol.30 , Issue.4 , pp. 796-800
    • Montejo, J.C.1    Grau, T.2    Acosta, J.3
  • 6
    • 34248210092 scopus 로고    scopus 로고
    • The impact of admission diagnosis on gastric emptying in critically ill patients
    • Nguyen NQ, Ng MP, Chapman M, et al. The impact of admission diagnosis on gastric emptying in critically ill patients. Critical Care 2007;11(1): R16. [http://dx.doi.org/10.1186/cc5685]
    • (2007) Critical Care , vol.11 , Issue.1
    • Nguyen, N.Q.1    Ng, M.P.2    Chapman, M.3
  • 7
    • 46149107325 scopus 로고    scopus 로고
    • Diminished functional association between proximal and distal gastric motility in critically ill patients
    • Nguyen NQ, Fraser RJ, Bryant LK, et al. Diminished functional association between proximal and distal gastric motility in critically ill patients. Intensive Care Med 2008;34(7): 1246-1255. [http://dx.doi.org/10.1007/s00134-008- 1036-5]
    • (2008) Intensive Care Med , vol.34 , Issue.7 , pp. 1246-1255
    • Nguyen, N.Q.1    Fraser, R.J.2    Bryant, L.K.3
  • 8
    • 0034891075 scopus 로고    scopus 로고
    • Small intestinal motor patterns in critically ill patients after major abdominal surgery
    • Tournadre J-P, Barclay M, Fraser R, et al. Small intestinal motor patterns in critically ill patients after major abdominal surgery. Am J Gastroenterol 2001;96: 2418-2426. [http://dx. doi. org/10.1111/j.1572-0241.2001. 03951.x]
    • (2001) Am J Gastroenterol , vol.96 , pp. 2418-2426
    • Tournadre, J.-P.1    Barclay, M.2    Fraser, R.3
  • 9
    • 67349161801 scopus 로고    scopus 로고
    • Determining small intestinal transit time and pathomorphology in critically ill patients using video capsule technology
    • Rauch S, Krueger K, Turan A, et al. Determining small intestinal transit time and pathomorphology in critically ill patients using video capsule technology. Intensive Care Med 2009;35: 1054-1059. [http://dx.doi.org/10.1007/ s00134-009-1415-6]
    • (2009) Intensive Care Med , vol.35 , pp. 1054-1059
    • Rauch, S.1    Krueger, K.2    Turan, A.3
  • 10
    • 0141464851 scopus 로고    scopus 로고
    • Stress-related mucosal disease in critically ill patients
    • Duerkson DR. Stress-related mucosal disease in critically ill patients. Best Prac Res Clin Gastroenterol 2003;17: 327-344. [http://dx.doi.org.ezproxy. uct.ac.za/10.1016/S1521-6918(03)00028-3]
    • (2003) Best Prac Res Clin Gastroenterol , vol.17 , pp. 327-344
    • Duerkson, D.R.1
  • 11
    • 79952490722 scopus 로고    scopus 로고
    • A new model to study intestinal ischemiareperfusion damage in Man
    • Derikx JP, Matthijsen RA, de Bruine AP, et al. A new model to study intestinal ischemiareperfusion damage in Man. J Surg Res 2011;166(2): 222-226. [http://dx.doi.org/10.1016/j. jss.2009.09.046]
    • (2011) J Surg Res , vol.166 , Issue.2 , pp. 222-226
    • Derikx, J.P.1    Matthijsen, R.A.2    De Bruine, A.P.3
  • 12
    • 33947310779 scopus 로고    scopus 로고
    • Relationship between disruption of the unstirred mucus layer and intestinal restitution in loss of gut barrier function after trauma hemorrhagic shock
    • Rupani B, Caputo FJ, Watkins AC, et al. Relationship between disruption of the unstirred mucus layer and intestinal restitution in loss of gut barrier function after trauma hemorrhagic shock. Surgery 2007;141(4): 481-489. [http://dx.doi.org.ezproxy.uct.ac.za/10.1016/j.surg.2006.10.008]
    • (2007) Surgery , vol.141 , Issue.4 , pp. 481-489
    • Rupani, B.1    Caputo, F.J.2    Watkins, A.C.3
  • 13
    • 33646102235 scopus 로고    scopus 로고
    • Altered gut flora and environment in patients with severe SIRS
    • Shimizu K, Ogura H, Goto M, et al. Altered gut flora and environment in patients with severe SIRS. J Trauma 2006;60: 126-133. [http://dx.doi.org/10. 1097/01.ta.0000197374.99755.fe]
    • (2006) J Trauma , vol.60 , pp. 126-133
    • Shimizu, K.1    Ogura, H.2    Goto, M.3
  • 14
    • 0028307435 scopus 로고
    • Intestinal microflora stimulates myoelectric activity of rat small intestine by promoting cyclic initiation and aboral propagation of migrating myoelectric complex
    • Husebye E, Hellstrom PM, Midtvedt T. Intestinal microflora stimulates myoelectric activity of rat small intestine by promoting cyclic initiation and aboral propagation of migrating myoelectric complex. Dig Dis Sci 1994;39: 946-956.
    • (1994) Dig Dis Sci , vol.39 , pp. 946-956
    • Husebye, E.1    Hellstrom, P.M.2    Midtvedt, T.3
  • 15
    • 33847229804 scopus 로고    scopus 로고
    • Effect of postoperative analgesia on major postoperative complications: A systematic update of the evidence
    • Liu SS, Wong CL. Effect of postoperative analgesia on major postoperative complications: A systematic update of the evidence. Anesth Analg 2007;104(3): 689-702. [http://dx.doi. org/10.1213/01.ane.0000255040.71600.41]
    • (2007) Anesth Analg , vol.104 , Issue.3 , pp. 689-702
    • Liu, S.S.1    Wong, C.L.2
  • 16
    • 0242363121 scopus 로고    scopus 로고
    • Prevention and treatment of gastrointestinal complications in patients on mechanical ventilation
    • Mutlu GM, Mutlu EA, Factor P. Prevention and treatment of gastrointestinal complications in patients on mechanical ventilation. Am J Respir Med 2003;2(5): 395-411. [http://dx.doi. org/10.1007/BF03256667]
    • (2003) Am J Respir Med , vol.2 , Issue.5 , pp. 395-411
    • Mutlu, G.M.1    Mutlu, E.A.2    Factor, P.3
  • 17
    • 33144476274 scopus 로고    scopus 로고
    • Multivariate analysis of factors associated with hospital readmission after intestinal surgery
    • Kariv Y, Wang W, Senagore AJ, et al. Multivariate analysis of factors associated with hospital readmission after intestinal surgery. Am J Surg 2006;191: 364-371. [http://dx.doi.org.10.1016/j. amjsurg.2005.10.038]
    • (2006) Am J Surg , vol.191 , pp. 364-371
    • Kariv, Y.1    Wang, W.2    Senagore, A.J.3
  • 18
    • 34547672652 scopus 로고    scopus 로고
    • Inhibition of sympathetic pathways restores postoperative ileus in the upper and lower gastrointestinal tract
    • Fukudo H, Tsuchida D, Koda K, et al. Inhibition of sympathetic pathways restores postoperative ileus in the upper and lower gastrointestinal tract. J Gastroenterol Hepatol 2007; 2: 1293-1299. [http://dx.doi.org/10.1111/j.1440- 1746.2007.04915.x]
    • (2007) J Gastroenterol Hepatol , vol.2 , pp. 1293-1299
    • Fukudo, H.1    Tsuchida, D.2    Koda, K.3
  • 19
    • 0030983591 scopus 로고    scopus 로고
    • Tachykinins in the gut. Part 1. Expression, release and motor function
    • Holzer P, Holzer-Petsche U. Tachykinins in the gut. Part 1. Expression, release and motor function. Pharmacol Ther 1997;73: 173-217.
    • (1997) Pharmacol Ther , vol.73 , pp. 173-217
    • Holzer, P.1    Holzer-Petsche, U.2
  • 20
    • 33845934742 scopus 로고    scopus 로고
    • Feed intolerance in critical illness is associated with increased basal and nutrient-stimulated plasma cholecystokinin concentrations
    • Nguyen N, Chapman M, Fraser R, et al. Feed intolerance in critical illness is associated with increased basal and nutrient-stimulated plasma cholecystokinin concentrations. Crit Care Med 2007;35(1): 82-88. [http://dx.doi.org/10.1097/01.CCM.0000250317.10791.6C]
    • (2007) Crit Care Med , vol.35 , Issue.1 , pp. 82-88
    • Nguyen, N.1    Chapman, M.2    Fraser, R.3
  • 21
    • 81455131419 scopus 로고    scopus 로고
    • Abnormalities in plasma motilin response to small intestinal nutrient stimulation in critically ill patients
    • Abstract
    • Nguyen NF, Bryant R, Burgstad L, et al. Abnormalities in plasma motilin response to small intestinal nutrient stimulation in critically ill patients. Gastroenterology 2010;138: S405. Abstract.
    • (2010) Gastroenterology , vol.138
    • Nguyen, N.F.1    Bryant, R.2    Burgstad, L.3
  • 22
    • 77956333680 scopus 로고    scopus 로고
    • Ion channel remodelling in gastrointestinal inflammation
    • Akbarli H, Hawkins EG, Ross GR, Kang M. Ion channel remodelling in gastrointestinal inflammation. Neurogastroenterol Motil 2010;22(10): 1045-1055. [http://dx.doi.org/10.1111/j.1365-2982.2010.01560.x]
    • (2010) Neurogastroenterol Motil , vol.22 , Issue.10 , pp. 1045-1055
    • Akbarli, H.1    Hawkins, E.G.2    Ross, G.R.3    Kang, M.4
  • 23
    • 33750603466 scopus 로고    scopus 로고
    • Intestinal permeability and cytokine inflammatory response in multiply injured patients
    • Spindler-Vesel A, Wraber B, Vovk I, Kompan L. Intestinal permeability and cytokine inflammatory response in multiply injured patients. J Interferon Cytokine Res 2006;26(10): 771-776. [http://dx.doi.org/10.1089/jir.2006.26.771]
    • (2006) J Interferon Cytokine Res , vol.26 , Issue.10 , pp. 771-776
    • Spindler-Vesel, A.1    Wraber, B.2    Vovk, I.3    Kompan, L.4
  • 24
    • 0141957168 scopus 로고    scopus 로고
    • Proinflammatory cytokines cause NO-dependent and independent changes in expression and localisation of tight junction proteins in intestinal epithelial cells
    • Han X, Fink MP, Delude RL. Proinflammatory cytokines cause NO-dependent and independent changes in expression and localisation of tight junction proteins in intestinal epithelial cells. Shock 2002;19: 229-237.
    • (2002) Shock , vol.19 , pp. 229-237
    • Han, X.1    Fink, M.P.2    Delude, R.L.3
  • 25
    • 57349177746 scopus 로고    scopus 로고
    • Gut hyper permeability after ischemia and reperfusion: Attenuation with adrenomedullin and its binding protein treatment
    • Higuchi A, Wu R, Zhou M, et al. Gut hyper permeability after ischemia and reperfusion: attenuation with adrenomedullin and its binding protein treatment. Int J Clin Exp Pathol 2008;1: 409-418.
    • (2008) Int J Clin Exp Pathol , vol.1 , pp. 409-418
    • Higuchi, A.1    Wu, R.2    Zhou, M.3
  • 26
    • 67649213624 scopus 로고    scopus 로고
    • The influence of the type of resuscitation fluid on gut injury and distant organ injury in a rat model of trauma/hemorrhagic shock
    • discussion 414-415
    • Vega D, Badami CD, Caputo FJ, et al. The influence of the type of resuscitation fluid on gut injury and distant organ injury in a rat model of trauma/hemorrhagic shock. J Trauma 2008;65(2): 409-414 (discussion 414-415). [http://dx.doi.org/10.1097/TA.0b013e3181719708]
    • (2008) J Trauma , vol.65 , Issue.2 , pp. 409-414
    • Vega, D.1    Badami, C.D.2    Caputo, F.J.3
  • 27
    • 34247235029 scopus 로고    scopus 로고
    • Toll-like receptor 2 controls mucosal inflammation by regulating epithelial barrier function
    • Cario E, Gerken G, Podolsky DK. Toll-like receptor 2 controls mucosal inflammation by regulating epithelial barrier function. Gastroenterology 2007;132(4): 1359-1374. [http://dx.doi. org/10.1053/j.gastro.2007.02.056]
    • (2007) Gastroenterology , vol.132 , Issue.4 , pp. 1359-1374
    • Cario, E.1    Gerken, G.2    Podolsky, D.K.3
  • 28
    • 69549114504 scopus 로고    scopus 로고
    • Butyrate enhances the intestinal barrier by facilitating tight junction assembly via activation of AMP activated protein kinase in Caco-2 cell monolayers
    • Peng LY, Li Z, Green RS, et al. Butyrate enhances the intestinal barrier by facilitating tight junction assembly via activation of AMP activated protein kinase in Caco-2 cell monolayers. J Nutr 2009;139: 1619-1625. [http://dx.doi.org/10.3945/jn.109.104638]
    • (2009) J Nutr , vol.139 , pp. 1619-1625
    • Peng, L.Y.1    Li, Z.2    Green, R.S.3
  • 29
    • 72449206050 scopus 로고    scopus 로고
    • Pro- and synbiotics to control inflammation and infection in patients with multiple injuries
    • Giamarellos-Bourboulis EJ, Bengmark S, Kanellakopoulou K, Kotzampassi K. Pro- and synbiotics to control inflammation and infection in patients with multiple injuries. J Trauma 2009;67: 815-821. [http://dx.doi.org/10.1097/TA. 0b013e31819d979e]
    • (2009) J Trauma , vol.67 , pp. 815-821
    • Giamarellos-Bourboulis, E.J.1    Bengmark, S.2    Kanellakopoulou, K.3    Kotzampassi, K.4
  • 30
    • 66149090738 scopus 로고    scopus 로고
    • Probiotic mixture VSL#3 protects the epithelial barrier by maintaining tight junction protein expression and preventing apoptosis in a murine model of colitis
    • Mennigen R, Nolte K, Rijcken E, et al. Probiotic mixture VSL#3 protects the epithelial barrier by maintaining tight junction protein expression and preventing apoptosis in a murine model of colitis. Am J Physiol Gastrointest Liver Physiol 2009;296(5): G1140-1149. [http://dx.doi. org/10.1152/ajpgi.90534. 2008]
    • (2009) Am J Physiol Gastrointest Liver Physiol , vol.296 , Issue.5
    • Mennigen, R.1    Nolte, K.2    Rijcken, E.3
  • 31
    • 41349089757 scopus 로고    scopus 로고
    • Probiotic prophylaxis in predicted severe acute pancreatitis: A randomised, double-blind, placebo-controlled trial
    • Besselink MGH, van Santvoort HC, Buskens E, et al. Probiotic prophylaxis in predicted severe acute pancreatitis: A randomised, double-blind, placebo-controlled trial. Ned Tijdschr Geneeskd 2008;152(12): 685-696.
    • (2008) Ned Tijdschr Geneeskd , vol.152 , Issue.12 , pp. 685-696
    • Besselink, M.G.H.1    Van Santvoort, H.C.2    Buskens, E.3
  • 32
    • 0347601676 scopus 로고    scopus 로고
    • Effects of intestinal surgery on pulmonary, glomerular, and intestinal permeability, and it relation to the hemodynamics and oxidative stress
    • Matejovic M, Krouzecky A, Rohyta R, et al. Effects of intestinal surgery on pulmonary, glomerular, and intestinal permeability, and it relation to the hemodynamics and oxidative stress. Surg Today 2004;34(1): 24-31. [http://dx.doi.org/10.1007/s00595-003-2642-z]
    • (2004) Surg Today , vol.34 , Issue.1 , pp. 24-31
    • Matejovic, M.1    Krouzecky, A.2    Rohyta, R.3
  • 33
    • 77952567595 scopus 로고    scopus 로고
    • Impact of not measuring residual gastric volume in mechanically ventilated patients receiving early enteral feeding: A prospective before-after study
    • Poulard F, Dimet J, Martin-Lefevre L, et al. Impact of not measuring residual gastric volume in mechanically ventilated patients receiving early enteral feeding: A prospective before-after study. J Parenter Enteral Nutr 2010;34(2): 125-130. [http://dx.doi. org/10.1177/0148607109344745]
    • (2010) J Parenter Enteral Nutr , vol.34 , Issue.2 , pp. 125-130
    • Poulard, F.1    Dimet, J.2    Martin-Lefevre, L.3
  • 34
    • 78650195039 scopus 로고    scopus 로고
    • Impact of enteral feeding protocols on enteral nutrition delivery: Results of a multicenter observational study
    • Heyland DK, Cahill NE, Dhaliwal R, et al. Impact of enteral feeding protocols on enteral nutrition delivery: Results of a multicenter observational study. J Parenter Enteral Nutr 2010;34(6): 675-684. [http://dx.doi.org/10.1177/ 0148607110364843]
    • (2010) J Parenter Enteral Nutr , vol.34 , Issue.6 , pp. 675-684
    • Heyland, D.K.1    Cahill, N.E.2    Dhaliwal, R.3
  • 36
    • 79957658882 scopus 로고    scopus 로고
    • Glucose absorption and small intestinal transit in critical illness
    • Deane AM, Summers MJ, Zaknic, et al. Glucose absorption and small intestinal transit in critical illness. Crit Care Med 2011;39(6): 1282-1288. [http://dx.doi.org/10.1097/CCM.0b013e31820ee21f]
    • (2011) Crit Care Med , vol.39 , Issue.6 , pp. 1282-1288
    • Deane, A.M.1    Summers, M.J.2    Zaknic3
  • 37
    • 58149161429 scopus 로고    scopus 로고
    • Gastric residual volume and aspiration in critically ill patients receiving gastric feedings
    • quiz 520
    • Metheny NA, Schallom L, Oliver DA, et al. Gastric residual volume and aspiration in critically ill patients receiving gastric feedings. Am J Crit Care 2008;17(6): 512-519 (quiz 520).
    • (2008) Am J Crit Care , vol.17 , Issue.6 , pp. 512-519
    • Metheny, N.A.1    Schallom, L.2    Oliver, D.A.3
  • 38
    • 79955635864 scopus 로고    scopus 로고
    • Altered gut flora are associated with septic complications and death in critically ill patients with systemic inflammatory response syndrome
    • Shimizu K, Ogura H, Hamasaki T, et al. Altered gut flora are associated with septic complications and death in critically ill patients with systemic inflammatory response syndrome. Dig Dis Sci 2011;56: 1171-1177. [http://dx.doi.org/10.1007/s10620-010-1418-8]
    • (2011) Dig Dis Sci , vol.56 , pp. 1171-1177
    • Shimizu, K.1    Ogura, H.2    Hamasaki, T.3
  • 39
    • 84873100864 scopus 로고    scopus 로고
    • Probioticsynbiotic therapy for treating critically ill patients from a gut microbiota perspective
    • [Epub ahead of print 19 Aug 2012]
    • Shimizu K, Ogura H, Asahara T, et al. Probiotic/synbiotic therapy for treating critically ill patients from a gut microbiota perspective. Dig Dis Sci 2013;58(1): 23-32. [Epub ahead of print 19 Aug 2012] [http://dx.doi.org/10.1007/ s10620-012-2334-x]
    • (2013) Dig Dis Sci , vol.58 , Issue.1 , pp. 23-32
    • Shimizu, K.1    Ogura, H.2    Asahara, T.3
  • 40
    • 77958006512 scopus 로고    scopus 로고
    • Probiotic prophylaxis of ventilator-associated pneumonia: A blinded, randomized, controlled trial
    • Morrow LE, Kollef MH, Casale TB. Probiotic prophylaxis of ventilator-associated pneumonia: A blinded, randomized, controlled trial. Am J Respir Crit Care Med 2010;182: 1058-1064. [http://dx.doi.org/10.1164/rccm. 200912-1853OC]
    • (2010) Am J Respir Crit Care Med , vol.182 , pp. 1058-1064
    • Morrow, L.E.1    Kollef, M.H.2    Casale, T.B.3
  • 41
    • 43349103474 scopus 로고    scopus 로고
    • The re-emerging role of intestinal microflora in critical illness and inflammation: Why the gut hypothesis of sepsis syndrome will not go away
    • Alverdy JC, Change EB. The re-emerging role of intestinal microflora in critical illness and inflammation: Why the gut hypothesis of sepsis syndrome will not go away. J Leukoc Biol 2008;83(3): 461-466. [http://dx.doi.org/10.1189/ jlb.0607372]
    • (2008) J Leukoc Biol , vol.83 , Issue.3 , pp. 461-466
    • Alverdy, J.C.1    Change, E.B.2
  • 42
    • 84862539480 scopus 로고    scopus 로고
    • Gastrointestinal function in intensive care patients: Terminology, definitions and management. recommendations of the esicm working group on abdominal problems
    • Blaser AR, Malbrain MLNG, Fruhwald S, et al. Gastrointestinal function in intensive care patients: Terminology, definitions and management. Recommendations of the ESICM Working Group on Abdominal Problems. Intensive Care Med 2012;38: 384-394. [http://dx.doi. org/10.1007/s00134-011-2459-y]
    • (2012) Intensive Care Med , vol.38 , pp. 384-394
    • Blaser, A.R.1    Malbrain, M.L.N.G.2    Fruhwald, S.3
  • 43
    • 79959740797 scopus 로고    scopus 로고
    • Acute intestinal failure in critically ill patients: Is plasma citrulline the right marker?
    • Piton G, Manzon C, Cypriant B, et al. Acute intestinal failure in critically ill patients: Is plasma citrulline the right marker? Intensive Care Med 2011;37: 911-917. [http://dx.doi.org/10.1007/s00134-011-2172-x]
    • (2011) Intensive Care Med , vol.37 , pp. 911-917
    • Piton, G.1    Manzon, C.2    Cypriant, B.3
  • 44
    • 34548682085 scopus 로고    scopus 로고
    • Intestinal crosstalk - A new paradigm for understanding the gut as the "motor" of critical illness
    • Clark JA, Coopersmith CM. Intestinal crosstalk - a new paradigm for understanding the gut as the "motor" of critical illness. Shock 2007;28(4): 384-393. [http://dx.doi.org/10.1097/shk.0b013e31805569df]
    • (2007) Shock , vol.28 , Issue.4 , pp. 384-393
    • Clark, J.A.1    Coopersmith, C.M.2


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