Effects of sodium hyaluronate in children with recurrent upper respiratory tract infections: Results of a randomised controlled study

International Journal of Immunopathology and Pharmacology

Volumn 26, Issue 1, 2013, Pages 127-135

  Macchi, Alberto ^a   Castelnuovo, P ^a   Terranova, P ^a   Digilio, E ^a  

^a UNIVERSITY OF INSUBRIA   (Italy)

Author keywords

9 mg sodium hyaluronate; Ciliary motility; Nasal wash device

Indexed keywords

HYALURONIC ACID; PLACEBO; SODIUM CHLORIDE;

ADENOID HYPERTROPHY; ARTICLE; BIOFILM; CHILDHOOD DISEASE; CILIARY MOTILITY; CLINICAL ARTICLE; CLINICAL EVALUATION; CONTROLLED STUDY; CYTOLOGY; DOUBLE BLIND PROCEDURE; DYSPNEA; ENDOSCOPY; EOSINOPHIL; FEMALE; HUMAN; MALE; MAST CELL; NEBULIZATION; NEUTROPHIL; OTITIS MEDIA; PHARYNGITIS; PILOT STUDY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RATING SCALE; RECURRENT DISEASE; RHINITIS; UPPER RESPIRATORY TRACT INFECTION; CHILD; DRUG EFFECT; DRUG EFFICACY; MAJOR CLINICAL STUDY; MICROBIOLOGICAL EXAMINATION; NONHUMAN; OPEN STUDY; PATIENT COMPLIANCE; PRESCHOOL CHILD; RECURRENT INFECTION; TREATMENT DURATION; TREATMENT OUTCOME;

EID: 84881258952     PISSN: 03946320     EISSN: None     Source Type: Journal    
DOI: 10.1177/039463201302600112     Document Type: Article

References (25)

1. Baraniuk JN, Shizari T, Sabol M, Ali M, Underhill CB. Hyaluronan is exocytosed from serous, but not mucous cells, of human nasal and tracheobronchial submucosal glands. J Investig Med 1996; 44:47-52. (Pubitemid 126820663)
2. Green SJ, Tarone G, Underhill CB. Aggregation of macrophages and fibroblasts is inhibited by a monoclonal antibody to the hyaluronate receptor. Exp Cell Res 1988; 178:224-32.
3. Krasiński R, Tchórzewski H. Hyaluronan-mediated regulation of inflammation. Postepy Hig Med Dosw (Online) 2007; 61:683-9.
4. Hallén L, Johansson C, Laurent C, Dahlqvist A. Hyaluronan localization in the rabbit larynx. Anat Rec 1996; 246:441-5. (Pubitemid 26415289)
5. Mullol J, Chowdhury BA, White MV, et al. Endothelin in human nasal mucosa. Am J Respir Cell Mol Biol 1993; 8:393-402.
6. Tanaka Y, Makiyama Y, Mitsui Y. Endothelin-1 is involved in the growth promotion of vascular smooth muscle cells by hyaluronic acid. Int J Cardiol 2000; 76:39-47.
7. Casalino-Matsuda SM, Monzon ME, Day AJ, Forteza RM. Hyaluronan fragments/CD44 mediate oxidative stress-induced MUC5B up-regulation in airway epithelium. Am J Respir Cell Mol Biol 2009; 40:277-85.
8. Balasz EA, Denlinger JL The role of hyaluronic acid in arthritis and its therapeutic use. In: Peyron JC, editor. Osteoarthritis current clinical and fundamental problems. Basel: Geigy; 1984. p. 165-74.
9. Migliore A, Granata M. Intra-articular use of hyaluronic acid in the treatment of osteoarthritis Clin Interv Aging 2008; 3:365-9. (Pubitemid 352037875)
10. Partsch G, Schwartzer C, Neumuller J, Dunky A, Petera P, Broll H, Ittner G, Jantsch S. Modulation of chemotaxis and migration of PMN cells by hyaluronic acid. Z Rheumatol 1989; 48:123-8. (Pubitemid 19166093)
11. Petrigni G, Allegra L. Aerosolised hyaluronic acid prevents exercise-induced bronchoconstriction, suggesting novel hypotheses on the correction of matrix defects in asthma. Pulm Pharmacol Ther 2006; 19:166-71.
12. Venge P, Pedersen B, Håkansson L, Hällgren R, Lindblad G, Dahl R. Subcutaneous administration of hyaluronan reduces the number of infectious exacerbations in patients with chronic bronchitis. Am J Respir Crit Care Med 1996; 153:312-6. (Pubitemid 26026868)
13. Modrzyński M. Hyaluronic acid gel in the treatment of empty nose syndrome. Am J Rhinol Allergy 2011; 25:103-6.
14. Corbo GM, Foresi A, Bonfitto P, Mugnano A, Agabiti N, Cole PJ. Measurement of nasal mucociliary clearance. Arch Dis Child 1989; 64:546-50. (Pubitemid 19104114)
15. Yadav J, Ranga RK, Singh J, Gathwala G. Nasal mucociliary clearance in healthy children in a tropical country. Int J Pediatr Otorhinolaryngol 2001; 57:21-4. (Pubitemid 32112137)
16. Davidson AE, Miller SD, Settipane RJ, Ricci AR, Klein DE, Settipane GA. Delayed nasal mucociliary clearance in patients with nonallergic rhinitis and nasal eosinophilia. Allergy Proc 1992; 13:81-4.
17. Cohen NA. Sinonasal mucociliary clearance in health and disease. Ann Otol Rhinol Laryngol 2006; 196(S):20-6.
18. Chen B, Antunes MB, Claire SE, Palmer JN, Chiu AG, Kennedy DW, Cohen NA. Reversal of chronic rhinosinusitis-associated sinonasal ciliary dysfunction. Am J Rhinol 2007; 21:346-53. (Pubitemid 46991965)
19. Carson JL, Collier AM, Hu SS. Acquired ciliary defects in nasal epithelium of children with acute viral upper respiratory infections. N Engl J Med 1985; 312:463-8. (Pubitemid 15130628)
20. Wilson R, Alton E, Rutman A, Higgins P, Al Nakib W, Geddes DM, Tyrrell DA, Cole PJ. Upper respiratory tract viral infection and mucociliary clearance. Eur J Respir Dis 1987; 70:272-9. (Pubitemid 17082230)
21. Zahm JM, Milliot M, Bresin A, Coraux C, Birembaut P. The effect of hyaluronan on airway mucus transport and airway epithelial barrier integrity: potential application to the cytoprotection of airway tissue. Matrix Biol 2011; 30:389-95.
22. Forteza R, Lieb T, Aoki T, Savani RC, Conner GE, Salathe M. Hyaluronan serves a novel role in airway mucosal host defense. FASEB J 2001; 15:2179-86. (Pubitemid 32927935)
23. Shoseyov D, Bibi H, Shai P, Shoseyov N, Shazberg G, Hurvitz H. Treatment with hypertonic saline versus normal saline nasal wash of pediatric chronic sinusitis. J Allergy Clin Immunol 1998; 101:602-5. (Pubitemid 28228302)
24. Hauptman G, Ryan MW. The effect of saline solutions on nasal patency and mucociliary clearance in rhinosinusitis patients. Otolaryngol Head Neck Surg 2007; 137:815-21. (Pubitemid 47632936)
25. Keojampa BK, Nguyen MH, Ryan MW. Effects of buffered saline solution on nasal mucociliary clearance and nasal airway patency. Otolaryngol Head Neck Surg 2004; 131:679-82. (Pubitemid 39446297)