Crystal structures of copper-depleted and copper-bound fungal pro-tyrosinase: Insights into endogenous cysteine-dependent copper incorporation

Journal of Biological Chemistry

Volumn 288, Issue 30, 2013, Pages 22128-22140

  Fujieda, Nobutaka ^a   Yabuta, Shintaro ^a   Ikeda, Takuya ^a   Oyama, Takuji ^a   Muraki, Norifumi ^a   Kurisu, Genji ^a   Itoh, Shinobu ^a  

^a OSAKA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE; DINUCLEAR COPPER; FUNGAL TYROSINASE; METAL HOMEOSTASIS; MULTIPLE PROCESS; PROTEIN SHELLS; PROTEOLYTIC ACTIVATION; STRUCTURAL EXAMINATION;

AMINO ACIDS;

COPPER;

COPPER; CYSTEINE; HISTIDINE; LEUCINE; MONOPHENOL MONOOXYGENASE; PHENYLALANINE;

ARTICLE; ASPERGILLUS ORYZAE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; COVALENT BOND; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; HOMEOSTASIS; MOLECULAR MECHANICS; MUTATIONAL ANALYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN BINDING; PROTEIN CROSS LINKING; PROTEIN DEGRADATION; PROTEIN DEPLETION; PROTEIN DOMAIN; PROTEIN MOTIF; PROTEIN PROCESSING; PROTEIN STRUCTURE;

COPPER; COPPER CHAPERONE; COPPER TRANSPORT; POST-TRANSLATIONAL MODIFICATION; PROTEIN CROSS-LINKING; PROTEIN-DERIVED COFACTOR; TYROSINASE; ZYMOGEN;

AMINO ACID SEQUENCE; APOENZYMES; ASPERGILLUS ORYZAE; CATALYTIC DOMAIN; COPPER; CRYSTALLOGRAPHY, X-RAY; CYSTEINE; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME PRECURSORS; FUNGAL PROTEINS; HOLOENZYMES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MONOPHENOL MONOOXYGENASE; MUTAGENESIS, SITE-DIRECTED; PROTEIN BINDING; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 84881226821     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.477612     Document Type: Article

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