Application of an innovative design space optimization strategy to the development of LC methods for the simultaneous screening of antibiotics to combat poor quality medicines

Journal of Pharmaceutical and Biomedical Analysis

Volumn 85, Issue , 2013, Pages 83-92

  Mbinze, J K ^a,b   Dispas, A ^a   Lebrun, P ^a   Mbay, J Mavar Tayey ^b   Habyalimana, V ^a,c   Kalenda, N ^a,b   Rozet, E ^a   Hubert, Ph ^a   Marini, R D ^a  

^a UNIVERSITY OF LIÈGE   (Belgium)

^b UNIVERSITY OF KINSHASA   (Congo)

^c RWANDA BIOMEDICAL CENTER   (Rwanda)

Author keywords

Accuracy profile; Antibiotics and associated substances; Design of experiments; Design space; Method transfer; Poor quality medicines

Indexed keywords

AMOXICILLIN; AMPICILLIN; ANTIBIOTIC AGENT; CEFADROXIL; CEFOTAXIME; CEFTRIAXONE; CHLORAMPHENICOL; CIPROFLOXACIN; CLAVULANATE POTASSIUM; CLAVULANIC ACID; CLINDAMYCIN; DOXYCYCLINE; LEVOFLOXACIN; METRONIDAZOLE; MICROCRYSTALLINE CELLULOSE; NORFLOXACIN; PENICILLIN V; SULBACTAM; SULFAMETHOXAZOLE; TAZOBACTAM; TETRACYCLINE; TRIMETHOPRIM;

ACCURACY; ARTICLE; CONGO; DRUG QUALITY; DRUG SCREENING; HIGH TEMPERATURE; PH; PRIORITY JOURNAL; PROCESS OPTIMIZATION; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

ACCURACY PROFILE; ANTIBIOTICS AND ASSOCIATED SUBSTANCES; DESIGN OF EXPERIMENTS; DESIGN SPACE; METHOD TRANSFER; POOR QUALITY MEDICINES;

ANTI-BACTERIAL AGENTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID;

EID: 84881219418     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2013.06.036     Document Type: Article

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