Thymic stromal lymphopoietin induces migration in human airway smooth muscle cells

Scientific Reports

Volumn 3, Issue , 2013, Pages

  Redhu, Naresh Singh ^a,b   Shan, Lianyu ^a   Movassagh, Hesam ^a   Gounni, Abdelilah S ^a  

^a UNIVERSITY OF MANITOBA   (Canada)

^b BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; RAC1 PROTEIN; STAT3 PROTEIN; THYMIC STROMAL LYMPHOPOIETIN;

AIRWAY REMODELING; ASTHMA; CELL MOTION; CYTOSKELETON; DRUG EFFECTS; HUMAN; IMMUNOLOGY; METABOLISM; PATHOLOGY; SMOOTH MUSCLE FIBER; ARTICLE; DRUG EFFECT;

AIRWAY REMODELING; ASTHMA; CELL MOVEMENT; CYTOKINES; CYTOSKELETON; HUMANS; MYOCYTES, SMOOTH MUSCLE; RAC1 GTP-BINDING PROTEIN; STAT3 TRANSCRIPTION FACTOR;

EID: 84881190984     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep02301     Document Type: Article

References (34)

1. Kaminska, M. et al. Airway remodeling in subjects with severe asthma with or without chronic persistent airflow obstruction. J Allergy Clin Immunol 124, 45-51 e41-44 (2009).
2. Bentley, J. K. & Hershenson, M. B. Airway smooth muscle growth in asthma: proliferation, hypertrophy, and migration. Proc Am Thorac Soc 5, 89-96 (2008).
3. Pepe, C. et al. Differences in airway remodeling between subjects with severe and moderate asthma. J Allergy Clin Immunol 116, 544-549 (2005). (Pubitemid 41267126)
4. Ziegler, S. F. The role of thymic stromal lymphopoietin (TSLP) in allergic disorders. Curr Opin Immunol 22, 795-799 (2010).
5. Park, L. S. et al. Cloning of the murine thymic stromal lymphopoietin (TSLP) receptor: Formation of a functional heteromeric complex requires interleukin 7 receptor. J Exp Med 192, 659-670 (2000).
6. Roan, F. et al. The multiple facets of thymic stromal lymphopoietin (TSLP) during allergic inflammation and beyond. J Leukoc Biol 91, 877-886 (2012).
7. Redhu, N. S. & Gounni, A. S. Function and mechanisms of TSLP/TSLPR complex in asthma and COPD. Clin Exp Allergy 42, 994-1005 (2012).
8. Ito, T. et al. TSLP-activated dendritic cells induce an inflammatory T helper type 2 cell response through OX40 ligand. J Exp Med 202, 1213-1223 (2005). (Pubitemid 41586952)
9. Kitajima, M., Lee, H. C.,Nakayama, T.& Ziegler, S. F. TSLP enhances the function of helper type 2 cells. Eur J Immunol 41, 1862-1871 (2011).
10. Kaur, D. et al. Mast cell-airway smooth muscle crosstalk: the role of thymic stromal lymphopoietin. Chest 142, 76-85 (2012).
11. Zhang, K. et al. Constitutive and inducible thymic stromal lymphopoietin expression in human airway smooth muscle cells: role in chronic obstructive pulmonary disease. Am J Physiol Lung Cell Mol Physiol 293, L375-382 (2007). (Pubitemid 47205018)
12. Shan, L. et al. Thymic stromal lymphopoietin receptor-mediated IL-6 and CC/CXC chemokines expression in human airway smooth muscle cells: role of MAPKs (ERK1/2, p38, and JNK) and STAT3 pathways. J Immunol 184, 7134-7143 (2010).
13. Smelter, D. F. et al. Thymic stromal lymphopoietin in cigarette smoke-exposed human airway smooth muscle. J Immunol 185, 3035-3040 (2010).
14. Fernandez, M. I. et al. The human cytokine TSLP triggers a cell-autonomous dendritic cell migration in confined environments. Blood 118, 3862-3869 (2011).
15. Simeone-Penney, M. C. et al. PDGF-induced human airway smooth muscle cell proliferation requires STAT3 and the small GTPase Rac1. Am J Physiol Lung Cell Mol Physiol 294, L698-704 (2008). (Pubitemid 351520102)
16. Disanza, A. et al. Actin polymerization machinery: the finish line of signaling networks, the starting point of cellular movement. Cell Mol Life Sci 62, 955-970 (2005). (Pubitemid 40655613)
17. Gerthoffer, W. T. Migration of airway smooth muscle cells. Proc AmThorac Soc 5, 97-105 (2008).
18. Johnson, P. R. et al. Airway smooth muscle cell proliferation is increased in asthma. Am J Respir Crit Care Med 164, 474-477 (2001). (Pubitemid 32778219)
19. Camoretti-Mercado, B. Targeting the airway smooth muscle for asthma treatment. Transl Res 154, 165-174 (2009).
20. Chen, Z. G. et al. Neutralization of TSLP Inhibits Airway Remodeling in aMurine Model of Allergic Asthma Induced by Chronic Exposure to House Dust Mite. PLoS One 8, e51268 (2013).
21. Reche, P. A. et al. Human thymic stromal lymphopoietin preferentially stimulates myeloid cells. J Immunol 167, 336-343 (2001). (Pubitemid 32567797)
22. Ying, S. et al. Expression and cellular provenance of thymic stromal lymphopoietin and chemokines in patients with severe asthma and chronic obstructive pulmonary disease. J Immunol 181, 2790-2798 (2008).
23. Scheeren, F. A. et al. Thymic stromal lymphopoietin induces early human B-cell proliferation and differentiation. Eur J Immunol 40, 955-965 (2010).
24. Rochman, Y. & Leonard, W. J. Thymic stromal lymphopoietin: a new cytokine in asthma. Curr Opin Pharmacol 8, 249-254 (2008).
25. Wong, C. K., Hu, S., Cheung, P. F. & Lam, C.W. Thymic stromal lymphopoietin induces chemotactic and prosurvival effects in eosinophils: implications in allergic inflammation. Am J Respir Cell Mol Biol 43, 305-315 (2010).
26. Semlali, A., Jacques, E., Koussih, L., Gounni, A. S. & Chakir, J. Thymic stromal lymphopoietin-induced human asthmatic airway epithelial cell proliferation through an IL-13-dependent pathway. J Allergy Clin Immunol 125, 844-850 (2010).
27. Simeone-Penney, M. C. et al. Airway epithelial STAT3 is required for allergic inflammation in a murine model of asthma. J Immunol 178, 6191-6199 (2007). (Pubitemid 46717401)
28. Saleh, A., Shan, L.,Halayko, A. J., Kung, S. & Gounni, A. S. Critical role for STAT3 in IL-17A-mediated CCL11 expression in human airway smooth muscle cells. J Immunol 182, 3357-3365 (2009).
29. Page, K. et al. Regulation of cyclin D(1) expression and DNA synthesis by phosphatidylinositol 3-kinase in airway smooth muscle cells. AmJ Respir Cell Mol Biol 23, 436-443 (2000).
30. Doanes, A. M., Irani, K., Goldschmidt-Clermont, P. J. & Finkel, T. A requirement for rac1 in the PDGF-stimulated migration of fibroblasts and vascular smooth cells. Biochem Mol Biol Int 45, 279-287 (1998). (Pubitemid 28331940)
31. Redhu, N. S., Saleh, A., Halayko, A. J., Ali, A. S. & Gounni, A. S. Essential role of NF-kappaB and AP-1 transcription factors in TNF-alpha-induced TSLP expression in human airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol 300, L479-485 (2011).
32. Redhu, N. S. et al. IgE induces transcriptional regulation of thymic stromal lymphopoietin in human airway smooth muscle cells. J Allergy Clin Immunol 128, 892-896 e892 (2011).
33. Gosens, R. et al. Role of caveolin-1 in p42/p44 MAP kinase activation and proliferation of human airway smooth muscle. AmJ Physiol Lung Cell Mol Physiol 291, L523-534 (2006). (Pubitemid 44343730)
34. Zhang, J. et al. Pentraxin 3 (PTX3) expression in allergic asthmatic airways: role in airway smooth muscle migration and chemokine production. PLoS One 7, e34965 (2012).