Asymmetric total synthesis of Tofacitinib

Tetrahedron Letters

Volumn 54, Issue 37, 2013, Pages 5096-5098

  Maricán, Adolfo ^a   Simirgiotis, Mario J ^b   Santos, Leonardo S ^a  

^a UNIVERSIDAD DE TALCA   (Chile)

^b UNIVERSIDAD DE ANTOFAGASTA   (Chile)

Author keywords

Alane reduction; CP 690,550; JAK3 inhibitor; Mitsunobu reaction

Indexed keywords

5 HYDROXYPIPERIDIN 2 ONE; JANUS KINASE 3 INHIBITOR; TERT BUTYL 3 HYDROXY 4 METHYLPIPERIDINE 1 CARBOXYLATE; TOFACITINIB; UNCLASSIFIED DRUG;

ARTICLE; ASYMMETRIC SYNTHESIS; CHEMICAL REACTION; DRUG POTENCY; EPIMERIZATION; LARGE SCALE PRODUCTION; MITSUNOBU REACTION; STEREOCHEMISTRY;

EID: 84881182806     PISSN: 00404039     EISSN: 18733581     Source Type: Journal    
DOI: 10.1016/j.tetlet.2013.07.042     Document Type: Article

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