Comparative analysis of survival, treatment, cost and resource use among patients newly diagnosed with brain metastasis by initial primary cancer

Journal of Neuro-Oncology

Volumn 114, Issue 1, 2013, Pages 117-125

  Ray, Saurabh ^a   Dacosta Byfield, Stacey ^b   Ganguli, Arijit ^a   Bonthapally, Vijayveer ^a   Teitelbaum, April ^b  

^a ABBOTT LABORATORIES   (United States)

^b OPTUM   (United States)

Author keywords

Brain metastasis; Burden of illness; Cost; Primary tumor; Survival

Indexed keywords

ANTICOAGULANT AGENT; ANTIDEPRESSANT AGENT; CORTICOSTEROID; NONSTEROID ANTIINFLAMMATORY AGENT; OPIATE;

ADULT; AGED; ARTICLE; BONE METASTASIS; BRAIN METASTASIS; BRAIN RADIATION; BREAST CANCER; CANCER MORTALITY; CANCER PALLIATIVE THERAPY; CANCER RADIOTHERAPY; CANCER SURVIVAL; CANCER THERAPY; COHORT ANALYSIS; COMPARATIVE STUDY; CONTROLLED STUDY; FEMALE; FOLLOW UP; HEALTH CARE COST; HEALTH CARE UTILIZATION; HOSPICE CARE; HUMAN; LENGTH OF STAY; LONGITUDINAL STUDY; LUNG CANCER; LUNG METASTASIS; MAJOR CLINICAL STUDY; MALE; MEDICARE; MELANOMA; OUTPATIENT CARE; RETROSPECTIVE STUDY; STEREOTACTIC RADIOSURGERY; SURVIVAL RATE; SURVIVAL TIME;

BRAIN NEOPLASMS; BREAST NEOPLASMS; COSTS AND COST ANALYSIS; DELIVERY OF HEALTH CARE; FEMALE; HEALTH RESOURCES; HUMANS; LONGITUDINAL STUDIES; LUNG NEOPLASMS; MALE; MELANOMA; MIDDLE AGED; RETROSPECTIVE STUDIES; SURVIVAL ANALYSIS;

EID: 84881172181     PISSN: 0167594X     EISSN: 15737373     Source Type: Journal    
DOI: 10.1007/s11060-013-1160-0     Document Type: Article

References (28)

1. Gori S, Rimondini S, De Angelis V et al (2007) Central nervous system metastases in HER-2 positive metastatic breast cancer patients treated with trastuzumab: incidence, survival, and risk factors. Oncologist 12:766-773
2. Mamon HJ, Yeap BY, Janne PA et al (2005) High risk of brain metastases in surgically staged IIIA non-small-cell lung cancer patients treated with surgery, chemotherapy, and radiation. J Clin Oncol 23:1530-1537
3. Davies MA, Liu P, McIntyre S et al (2011) Prognostic factors for survival in melanoma patients with brain metastases. Cancer 117:1687-1696
4. Eichler AF, Loeffler JS (2007) Multidisciplinary management of brain metastases. Oncologist 12:884-898
5. Gavrilovic IT, Posner JB (2005) Brain metastases: epidemiology and pathophysiology. J Neurooncol 75:5-14
6. Lagerwaard FJ, Levendag PC, Nowak PJ, Eijkenboom WM, Hanssens PE, Schmitz PI (1999) Identification of prognostic factors in patients with brain metastases: a review of 1292 patients. Int J Radiat Oncol Biol Phys 43:795-803
7. Tsao MN, Lloyd N, Wong RK et al (2012) Whole brain radiotherapy for the treatment of newly diagnosed multiple brain metastases. Cochrane database Syst Rev 4:CD003869
8. Pollock BE, Brown PD, Foote RL, Stafford SL, Schomberg PJ (2003) Properly selected patients with multiple brain metastases may benefit from aggressive treatment of their intracranial disease. J Neurooncol 61:73-80
9. Nieder C, Norum J, Stemland JG, Dalhaug A (2010) Resource utilization in patients with brain metastases managed with best supportive care, radiotherapy and/or surgical resection: a Markov analysis. Oncology 78:348-355
10. Bennett CL, Tigue CC, Fitzner KA (2007) The economics of brain metastases. Cancer Treat Res 136:23-29
11. Ganguli A, Henk H, Teitelbaum A, Ray S (2011) Burden of Brain Metastasis in a Metastatic Non-small Cell Lung Cancer (NSCLC) Population. Poster presented at International Society for Pharmacoeconomics and Outcomes Research 14th Annual European Congress, Madrid, Spain, 5-8 November, 2011
12. Pelletier EM, Shim B, Goodman S, Amonkar MM (2008) Epidemiology and economic burden of brain metastases among patients with primary breast cancer: results from a US claims data analysis. Breast Cancer Res Treat 108:297-305
13. US Department of Health and Human Services. Health Insurance Portability and Accountability Act of 1996. Public Law 104-191, 104th Congress. http://www.cms.gov/HIPAAGenInfo/Downloads/HIPAALaw.pdf. Accessed 27 October 2012
14. Quan H, Sundararajan V, Halfon P et al (2005) Coding algorithms for defining comorbidities in ICD-9-CM and ICD-10 administrative data. Med Care 43:1130-1139
15. US Department of Health and Human Services. Consumer Price Index-Chained Consumer Price Index. http://data.bls.gov/cgi-bin/surveymost. Accessed 27 October 2012
16. Barnholtz-Sloan JS, Sloan AE, Davis FG, Vigneau FD, Lai P, Sawaya RE (2004) Incidence proportions of brain metastases in patients diagnosed (1973 to 2001) in the Metropolitan Detroit Cancer Surveillance System. J Clin Oncol 22:2865-2872
17. Lassman AB, DeAngelis LM (2003) Brain metastases. Neurol Clin 21:1-23, vii
18. Hillner BE, Kirkwood JM, Agarwala SS (2001) Burden of illness associated with metastatic melanoma: an audit of 100 consecutive referral center cases. Cancer 91:1814-1821
19. Staudt M, Lasithiotakis K, Leiter U et al (2010) Determinants of survival in patients with brain metastases from cutaneous melanoma. Br J Cancer 102:1213-1218
20. Pestalozzi BC, Zahrieh D, Price KN et al (2006) Identifying breast cancer patients at risk for central nervous system (CNS) metastases in trials of the International Breast Cancer Study Group (IBCSG). Ann Oncol 17:935-944
21. Arrieta O, Saavedra-Perez D, Kuri R et al (2009) Brain metastasis development and poor survival associated with carcinoembryonic antigen (CEA) level in advanced non-small cell lung cancer: a prospective analysis. BMC Cancer 9:119
22. Carey LA, Ewend MG, Metzger R et al (2004) Central nervous system metastases in women after multimodality therapy for high risk breast cancer. Breast Cancer Res Treat 88:273-280
23. Gonzalez-Angulo AM, Cristofanilli M, Strom EA et al (2004) Central nervous system metastases in patients with high-risk breast carcinoma after multimodality treatment. Cancer 101:1760-1766
24. Eigentler TK, Figl A, Krex D et al (2011) Number of metastases, serum lactate dehydrogenase level, and type of treatment are prognostic factors in patients with brain metastases of malignant melanoma. Cancer 117:1697-1703
25. Fife KM, Colman MH, Stevens GN et al (2004) Determinants of outcome in melanoma patients with cerebral metastases. J Clin Oncol 22:1293-1300
26. Daryanani D, Plukker JT, de Jong MA et al (2005) Increased incidence of brain metastases in cutaneous head and neck melanoma. Melanoma Res 15:119-124
27. Villa S, Weber DC, Moretones C et al (2011) Validation of the new graded prognostic assessment scale for brain metastases: a multicenter prospective study. Radiat Oncol 6:23
28. Ono M, Ando M, Yunokawa M et al (2009) Brain metastases in patients who receive trastuzumab-containing chemotherapy for HER2-overexpressing metastatic breast cancer. Int J Clin Oncol 14:48-52