Computed tomographic measures of pulmonary vascular morphology in smokers and their clinical implications

American Journal of Respiratory and Critical Care Medicine

Volumn 188, Issue 2, 2013, Pages 231-239

  Estépar, Raúl San José ^a   Kinney, Gregory L ^b   Black Shinn, Jennifer L ^b   Bowler, Russell P ^c   Kindlmann, Gordon L ^d   Ross, James C ^a   Kikinis, Ron ^a   Han, Meilan K ^e   Come, Carolyn E ^a   Diaz, Alejandro A ^a   Cho, Michael H ^a   Hersh, Craig P ^a   Schroeder, Joyce D ^c   Reilly, John J ^f   Lynch, David A ^c   Crapo, James D ^g   Wells, J Michael ^h   Dransfield, Mark T ^h   Hokanson, John E ^b   Washko, George R ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b Department of Civil and Environmental Engineering at Colorado State University and the Department of Environmental and Occupational Health at the Colorado School of Public Health   (United States)

^c DEPARTMENT OF MEDICINE   (United States)

^d THE UNIVERSITY OF CHICAGO   (United States)

^e UNIVERSITY OF MICHIGAN   (United States)

^f UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^g NATIONAL JEWISH MEDICAL AND RESEARCH CENTER   (United States)

^h UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

COPD; CT scan; Pulmonary vasculature morphology; Smoking

Indexed keywords

CARBON MONOXIDE;

AIRWAY OBSTRUCTION; ARTICLE; BODY MASS; BREATH ANALYSIS; CHRONIC OBSTRUCTIVE LUNG DISEASE; COMPUTER ASSISTED TOMOGRAPHY; CONE BEAM COMPUTED TOMOGRAPHY; CONTROLLED STUDY; DISEASE SEVERITY; DYSPNEA; EXERCISE; FEMALE; HUMAN; LUNG BLOOD VESSEL; LUNG EMPHYSEMA; MAJOR CLINICAL STUDY; MALE; OXYGEN SATURATION; PRIORITY JOURNAL; SMOKING; ST. GEORGE RESPIRATORY QUESTIONNAIRE; WALKING SPEED;

AGED; ANGIOGRAPHY; BLOOD VESSELS; BODY MASS INDEX; FEMALE; HUMANS; LUNG; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; PULMONARY DIFFUSING CAPACITY; SEVERITY OF ILLNESS INDEX; SMOKING; TOMOGRAPHY, X-RAY COMPUTED;

EID: 84881145848     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201301-0162OC     Document Type: Article

References (45)

1. ChatilaWM, Thomashow BM, MinaiOA, Criner GJ,Make BJ. Comorbidities in chronic obstructive pulmonary disease. Proc Am Thorac Soc 2008; 5: 549-555.
2. Falk JA, Kadiev S, Criner GJ, Scharf SM, Minai OA, Diaz P. Cardiac disease in chronic obstructive pulmonary disease. Proc Am Thorac Soc 2008;5: 543-548.
3. Chaouat A, Naeije R, Weitzenblum E. Pulmonary hypertension in COPD. Eur Respir J 2008;32: 1371-1385.
4. Minai OA, Chaouat A, Adnot S. Pulmonary hypertension in COPD: epidemiology, significance, and management: pulmonary vascular disease: the global perspective. Chest 2010;137(Suppl. 6):39S-51S.
5. Oswald-Mammosser M, Weitzenblum E, Quoix E, Moser G, Chaouat A, Charpentier C, Kessler R. Prognostic factors in COPD patients receiving long-term oxygen therapy. Importance of pulmonary artery pressure. Chest 1995;107: 1193-1198.
6. Kessler R, Faller M, Fourgaut G, Mennecier B, Weitzenblum E. Predictive factors of hospitalization for acute exacerbation in a series of 64 patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1999;159: 158-164.
7. Traver GA, Cline MG, Burrows B. Predictors of mortality in chronic obstructive pulmonary disease. A 15-year follow-up study. Am Rev Respir Dis 1979;119: 895-902.
8. Weitzenblum E, Hirth C, Ducolone A, Mirhom R, Rasaholinjanahary J, Ehrhart M. Prognostic value of pulmonary artery pressure in chronic obstructive pulmonary disease. Thorax 1981;36: 752-758.
9. Burgess MI, Mogulkoc N, Bright-Thomas RJ, Bishop P, Egan JJ, Ray SG. Comparison of echocardiographic markers of right ventricular function in determining prognosis in chronic pulmonary disease. J Am Soc Echocardiogr 2002;15: 633-639.
10. Incalzi RA, Fuso L, De Rosa M, Di Napoli A, Basso S, Pagliari G, Pistelli R. Electrocardiographic signs of chronic cor pulmonale: a negative prognostic finding in chronic obstructive pulmonary disease. Circulation 1999;99: 1600-1605.
11. Cordasco EM, Beerel FR, Vance JW, Wende RW, Toffolo RR. Newer aspects of the pulmonary vasculature in chronic lung disease. A comparative study. Angiology 1968;19: 399-407.
12. Scarrow GD. The pulmonary angiogram in chronic bronchitis and emphysema. Proc R Soc Med 1965;58: 684-687.
13. Jacobson G, Turner AF, Balchum OJ, Jung R. Vascular changes in pulmonary emphysema. The radiologic evaluation by selective and peripheral pulmonary wedge angiography. Am J Roentgenol Radium Ther Nucl Med 1967;100: 374-396.
14. Hale KA, Niewoehner DE, Cosio MG. Morphologic changes in the muscular pulmonary arteries: relationship to cigarette smoking, airway disease, and emphysema. Am Rev Respir Dis 1980;122: 273-278.
15. Wright JL, Lawson L, Paré PD, Hooper RO, Peretz DI, Nelems JM, Schulzer M, Hogg JC. The structure and function of the pulmonary vasculature in mild chronic obstructive pulmonary disease. The effect of oxygen and exercise. Am Rev Respir Dis 1983;128: 702-707.
16. Magee F, Wright JL, Wiggs BR, Paré PD, Hogg JC. Pulmonary vascular structure and function in chronic obstructive pulmonary disease. Thorax 1988;43: 183-189.
17. Barberà JA, Riverola A, Roca J, Ramirez J, Wagner PD, Ros D, Wiggs BR, Rodriguez-Roisin R. Pulmonary vascular abnormalities and ventilation-perfusion relationships in mild chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1994;149: 423-429.
18. Santos S, Peinado VI, Ramírez J,Melgosa T, Roca J, Rodriguez-Roisin R, Barberà JA. Characterization of pulmonary vascular remodelling in smokers and patients with mild COPD. Eur Respir J 2002;19: 632-638.
19. Washko GR. Rate of decline in FEV1: is emphysema the culprit? Am J Respir Crit Care Med 2012;185: 2-3.
20. Mohamed Hoesein FA, de Hoop B, Zanen P, Gietema H, Kruitwagen CL, van Ginneken B, Isgum I, Mol C, van Klaveren RJ, Dijkstra AE, et al. CT-quantified emphysema in male heavy smokers: association with lung function decline. Thorax 2011;66: 782-787.
21. Vestbo J, Edwards LD, Scanlon PD, Yates JC, Agusti A, Bakke P, Calverley PM, Celli B, Coxson HO, Crim C, et al.; ECLIPSE Investigators. Changes in forced expiratory volume in 1 second over time in COPD. N Engl J Med 2011;365: 1184-1192.
22. Han MK, Kazerooni EA, Lynch DA, Liu LX, Murray S, Curtis JL, Criner GJ, Kim V, Bowler RP, Hanania NA, et al.; COPDGene Investigators. Chronic obstructive pulmonary disease exacerbations in the COPDGene study: associated radiologic phenotypes. Radiology 2011;261: 274-282.
23. Matsuoka S, Washko GR, Dransfield MT, Yamashiro T, San Jose Estepar R, Diaz A, Silverman EK, Patz S, Hatabu H. Quantitative CT measurement of cross-sectional area of small pulmonary vessel in COPD: correlations with emphysema and airflow limitation. Acad Radiol 2010;17: 93-99.
24. Matsuoka S, Washko GR, Yamashiro T, San Jose Estepar R, Diaz A, Silverman EK, Hoffman E, Fessler HE, Criner GJ, Marchetti N, et al.; National Emphysema Treatment Trial Research Group. Pulmonary hypertension and computed tomography measurement of small pulmonary vessels in severe emphysema. Am J Respir Crit Care Med 2010;181: 218-225.
25. Regan EA, Hokanson JE, Murphy JR, Make B, Lynch DA, Beaty TH, Curran-Everett D, Silverman EK, Crapo JD. Genetic epidemiology of COPD (COPDGene) study design. COPD 2010;7: 32-43.
26. Zach JA, Newell JD Jr, Schroeder J,Murphy JR, Curran-Everett D, Hoffman EA,Westgate PM, Han MK, Silverman EK, Crapo JD, et al.; COPDGene Investigators. Quantitative computed tomography of the lungs and airways in healthy nonsmoking adults. Invest Radiol 2012;47: 596-602.
27. Standardization of spirometry, 1994 update. American Thoracic Society. Am J Respir Crit Care Med 1994;152: 1107-1136.
28. American Thoracic Society. Lung function testing: selection of reference values and interpretative strategies. Am Rev Respir Dis 1991;144: 1202-1218.
29. Jones PW, Quirk FH, Baveystock CM. The St George's respiratory questionnaire. Respir Med 1991;85(Suppl. B):25-31; discussion 33-27.
30. Mahler DA, Wells CK. Evaluation of clinical methods for rating dyspnea. Chest 1988;93: 580-586.
31. Celli BR, Cote CG, Marin JM, Casanova C, Montes de Oca M, Mendez RA, Pinto Plata V, Cabral HJ. The body-mass index, airflow obstruction, dyspnea, and exercise capacity index in chronic obstructive pulmonary disease. N Engl J Med 2004;350: 1005-1012.
32. Ross JC, San Jose Estepar R, Kindlmann G, Diaz A, Westin CF, Silverman EK, Washko GR. Automatic lung lobe segmentation using particles, thin plate splines, and maximum a posteriori estimation. Med Image Comput Comput Assist Interv 2010;13: 163-171.
33. Washko GRHG, Hunninghake GM, Fernandez IE, Nishino M, Okajima Y, Yamashiro T, Ross JC, Estépar RS, Lynch DA, Brehm JM, et al.; COPDGene Investigators. Lung volumes and emphysema in smokers with interstitial lung abnormalities. N Engl J Med 2011;364: 897-906.
34. Kindlmann GL, San José Estépar R, Smith SM, Westin CF. Sampling and visualizing creases with scale-space particles. IEEE Trans Vis Comput Graph 2009;15: 1415-1424.
35. San Jose Estepar RRJ, Krissian K, Schultz T,Washko GR, Kindlmann GL. Computational vascular morphometry for the assessment of pulmonary vascular disease based on scale-space particles. In: Biomedical Imaging (ISBI), 2012 9th IEEE International Symposium on. IEEE; 2012. pp. 1479-1482.
36. Matsuoka S, Yamashiro T, Diaz A, Estépar RS, Ross JC, Silverman EK, Kobayashi Y, Dransfield MT, Bartholmai BJ, Hatabu H, et al. The relationship between small pulmonary vascular alteration and aortic atherosclerosis in chronic obstructive pulmonary disease: quantitative CT analysis. Acad Radiol 2011;18: 40-46.
37. Wan ES, Hokanson JE, Murphy JR, Regan EA, Make BJ, Lynch DA, Crapo JD, Silverman EK; COPDGene Investigators. Clinical and radiographic predictors of GOLD-unclassified smokers in the COPDGene study. Am J Respir Crit Care Med 2011;184: 57-63.
38. Wells JM,Washko GR, Han MK, Abbas N, Nath H, Mamary AJ, Regan E, Bailey WC, Martinez FJ, Westfall E, et al.; COPDGene Investigators; ECLIPSE Study Investigators. Pulmonary arterial enlargement and acute exacerbations of COPD. N Engl J Med 2012;367: 913-921.
39. Barr RG, Bluemke DA, Ahmed FS, Carr JJ, Enright PL, Hoffman EA, Jiang R, Kawut SM, Kronmal RA, Lima JA, et al. Percent emphysema, airflow obstruction, and impaired left ventricular filling. N Engl JMed 2010;362: 217-227.
40. Weitzenblum E, Sautegeau A, Ehrhart M, Mammosser M, Pelletier A. Long-term oxygen therapy can reverse the progression of pulmonary hypertension in patients with chronic obstructive pulmonary disease. Am Rev Respir Dis 1985;131: 493-498.
41. Medical Research Council Working Party. Long term domiciliary oxygen therapy in chronic hypoxic cor pulmonale complicating chronic bronchitis and emphysema: report of the Medical Research Council Working Party. Lancet 1981;1: 681-686.
42. Nocturnal Oxygen Therapy Trial Group. Continuous or nocturnal oxygen therapy in hypoxemic chronic obstructive lung disease: a clinical trial. Ann Intern Med 1980;93: 391-398.
43. Archer SL, Mike D, Crow J, Long W, Weir EK. A placebo-controlled trial of prostacyclin in acute respiratory failure in COPD. Chest 1996; 109: 750-755.
44. Vonbank K, Ziesche R, Higenbottam TW, Stiebellehner L, Petkov V, Schenk P, Germann P, Block LH. Controlled prospective randomised trial on the effects on pulmonary haemodynamics of the ambulatory long term use of nitric oxide and oxygen in patients with severe COPD. Thorax 2003;58: 289-293.
45. Roger N, Barberà JA, Roca J, Rovira I, Gómez FP, Rodriguez-Roisin R. Nitric oxide inhalation during exercise in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1997;156: 800-806.