Group B Streptococcus pilus sortase regulation: A single mutation in the lid region induces pilin protein polymerization in vitro

FASEB Journal

Volumn 27, Issue 8, 2013, Pages 3144-3154

  Cozzi, Roberta ^a   Zerbini, Francesca ^a   Assfalg, Michael ^b   D'Onofrio, Mariapina ^b   Biagini, Massimiliano ^a   Martinelli, Manuele ^a   Nuccitelli, Annalisa ^a   Norais, Nathalie ^a   Telford, John L ^a   Maione, Domenico ^a,b   Rinaudo, C Daniela ^a  

^a NOVARTIS VACCINES AND DIAGNOSTICS   (Italy)

^b UNIVERSITY OF VERONA   (Italy)

Author keywords

Backbone protein; Limited proteolysis; NMR spectroscopy; Thermal stability; Transpeptidation

Indexed keywords

PILIN; SORTASE; AMINOACYLTRANSFERASE; BACTERIAL PROTEIN; CYSTEINE PROTEINASE; FIMBRIA PROTEIN; SORTASE C;

ARTICLE; BACTERIAL STRAIN; ENZYME ACTIVITY; ENZYME MECHANISM; ENZYME STABILITY; IN VITRO STUDY; MUTATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN POLYMERIZATION; PROTEIN STABILITY; STREPTOCOCCUS AGALACTIAE; THERMODYNAMICS; AMINO ACID SEQUENCE; BIOCATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; ENZYME ACTIVE SITE; ENZYMOLOGY; FIMBRIA; FLUOROMETRY; GENETICS; KINETICS; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PHYLOGENY; POLYMERIZATION; PROTEIN FOLDING; PROTEIN MOTIF; PROTEIN TERTIARY STRUCTURE; WESTERN BLOTTING;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; AMINOACYLTRANSFERASES; BACTERIAL PROTEINS; BIOCATALYSIS; BLOTTING, WESTERN; CATALYTIC DOMAIN; CYSTEINE ENDOPEPTIDASES; FIMBRIAE PROTEINS; FIMBRIAE, BACTERIAL; FLUOROMETRY; KINETICS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MUTATION; PHYLOGENY; POLYMERIZATION; PROTEIN FOLDING; PROTEIN STRUCTURE, TERTIARY; PROTEOLYSIS; STREPTOCOCCUS AGALACTIAE;

EID: 84881119934     PISSN: None     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.13-227793     Document Type: Article

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