-
1
-
-
33644851056
-
Tissue factor in cardiovascular diseases: Molecular mechanisms and clinical implications
-
Steffel, J., Luscher, T. F. & Tanner, F. C. Tissue factor in cardiovascular diseases: Molecular mechanisms and clinical implications. Circulation 113, 722-731 (2006).
-
(2006)
Circulation
, vol.113
, pp. 722-731
-
-
Steffel, J.1
Luscher, T.F.2
Tanner, F.C.3
-
2
-
-
34347394385
-
Meta-analysis: Antithrombotic therapy to prevent stroke in patients who have nonvalvular atrial fibrillation
-
Hart, R. G., Pearce, L. A. & Aguilar, M. I. Meta-analysis: Antithrombotic therapy to prevent stroke in patients who have nonvalvular atrial fibrillation. Ann. Intern. Med. 146, 857-867 (2007).
-
(2007)
Ann. Intern. Med.
, vol.146
, pp. 857-867
-
-
Hart, R.G.1
Pearce, L.A.2
Aguilar, M.I.3
-
3
-
-
84856699090
-
Executive summary: Antithrombotic therapy and prevention of thrombosis, 9th ed: American College of Chest Physicians evidence-based clinical practice guidelines
-
Guyatt, G. H. et al. Executive summary: Antithrombotic therapy and prevention of thrombosis, 9th ed: American College of Chest Physicians evidence-based clinical practice guidelines. Chest 141 (Suppl. 2), 7S-47S (2012).
-
(2012)
Chest
, vol.141
, Issue.SUPPL. 2
-
-
Guyatt, G.H.1
-
4
-
-
84873082514
-
Vitamin K antagonists: Ready to be replaced?
-
Steffel, J. & Luscher, T. F. Vitamin K antagonists: Ready to be replaced? Hamostaseologie 32, 249-257 (2012).
-
(2012)
Hamostaseologie
, vol.32
, pp. 249-257
-
-
Steffel, J.1
Luscher, T.F.2
-
5
-
-
79951688186
-
Changing anticoagulant paradigms for atrial fibrillation: Dabigatran, apixaban and rivaroxaban
-
Giorgi, M. A., Cohen Arazi, H., Gonzalez, C. D. & Di Girolamo, G. Changing anticoagulant paradigms for atrial fibrillation: Dabigatran, apixaban and rivaroxaban. Expert Opin. Pharmacother. 12, 567-577 (2011).
-
(2011)
Expert Opin. Pharmacother.
, vol.12
, pp. 567-577
-
-
Giorgi, M.A.1
Cohen Arazi, H.2
Gonzalez, C.D.3
Di Girolamo, G.4
-
6
-
-
55549103684
-
Monitoring direct FXa-inhibitors and fondaparinux by prothrombinase- induced clotting time (PiCT): Relation to FXa-activity and influence of assay modifications
-
Harder, S., Parisius, J. & Picard-Willems, B. Monitoring direct FXa-inhibitors and fondaparinux by prothrombinase-induced clotting time (PiCT): Relation to FXa-activity and influence of assay modifications. Thromb. Res. 123, 396-403 (2008).
-
(2008)
Thromb. Res.
, vol.123
, pp. 396-403
-
-
Harder, S.1
Parisius, J.2
Picard-Willems, B.3
-
7
-
-
80051668220
-
Emerging options in the treatment of deep vein thrombosis and pulmonary embolism
-
Brenner, B. & Hoffman, R. Emerging options in the treatment of deep vein thrombosis and pulmonary embolism. Blood Rev. 25, 215-221 (2011).
-
(2011)
Blood Rev.
, vol.25
, pp. 215-221
-
-
Brenner, B.1
Hoffman, R.2
-
8
-
-
38749131205
-
The metabolism and disposition of the oral direct thrombin inhibitor, dabigatran, in humans
-
Blech, S., Ebner, T., Ludwig-Schwellinger, E., Stangier, J. & Roth, W. The metabolism and disposition of the oral direct thrombin inhibitor, dabigatran, in humans. Drug Metab. Dispos. 36, 386-399 (2008).
-
(2008)
Drug Metab. Dispos.
, vol.36
, pp. 386-399
-
-
Blech, S.1
Ebner, T.2
Ludwig-Schwellinger, E.3
Stangier, J.4
Roth, W.5
-
9
-
-
77949421739
-
Influence of renal impairment on the pharmacokinetics and pharmacodynamics of oral dabigatran etexilate: An open-label, parallel-group, single-centre study
-
Stangier, J., Rathgen, K., Stahle, H. & Mazur, D. Influence of renal impairment on the pharmacokinetics and pharmacodynamics of oral dabigatran etexilate: An open-label, parallel-group, single-centre study. Clin. Pharmacokinet. 49, 259-268 (2010).
-
(2010)
Clin. Pharmacokinet.
, vol.49
, pp. 259-268
-
-
Stangier, J.1
Rathgen, K.2
Stahle, H.3
Mazur, D.4
-
10
-
-
34548031359
-
The pharmacokinetics, pharmacodynamics and tolerability of dabigatran etexilate, a new oral direct thrombin inhibitor, in healthy male subjects
-
Stangier, J., Rathgen, K., Stahle, H., Gansser, D. & Roth, W. The pharmacokinetics, pharmacodynamics and tolerability of dabigatran etexilate, a new oral direct thrombin inhibitor, in healthy male subjects. Br. J. Clin. Pharmacol. 64, 292-303 (2007).
-
(2007)
Br. J. Clin. Pharmacol.
, vol.64
, pp. 292-303
-
-
Stangier, J.1
Rathgen, K.2
Stahle, H.3
Gansser, D.4
Roth, W.5
-
11
-
-
77953168824
-
Dabigatran etexilate-A novel, reversible, oral direct thrombin inhibitor: Interpretation of coagulation assays and reversal of anticoagulant activity
-
van Ryn, J. et al. Dabigatran etexilate-A novel, reversible, oral direct thrombin inhibitor: Interpretation of coagulation assays and reversal of anticoagulant activity. Thromb. Haemost. 103, 1116-1127 (2010).
-
(2010)
Thromb. Haemost.
, vol.103
, pp. 1116-1127
-
-
Van Ryn, J.1
-
12
-
-
84862530985
-
A randomized trial of dabigatran versus warfarin in the treatment of acute venous thromboembolism (RE-COVER II) [abstract 205]
-
Schulman, S. et al. A randomized trial of dabigatran versus warfarin in the treatment of acute venous thromboembolism (RE-COVER II) [abstract 205]. Presented at the American Society of Hematology 2011 Annual Meeting.
-
Presented at the American Society of Hematology 2011 Annual Meeting
-
-
Schulman, S.1
-
13
-
-
35449007749
-
Oral dabigatran etexilate vs. Subcutaneous enoxaparin for the prevention of venous thromboembolism after total knee replacement: The REMODEL randomized trial
-
Eriksson, B. I. et al. Oral dabigatran etexilate vs. subcutaneous enoxaparin for the prevention of venous thromboembolism after total knee replacement: The REMODEL randomized trial. J. Thromb. Haemost. 5, 2178-2185 (2007).
-
(2007)
J. Thromb. Haemost.
, vol.5
, pp. 2178-2185
-
-
Eriksson, B.I.1
-
14
-
-
57649123692
-
Oral thrombin inhibitor dabigatran etexilate vs North American enoxaparin regimen for prevention of venous thromboembolism after knee arthroplasty surgery
-
RE-MOBILIZE Writing Committee, et al
-
RE-MOBILIZE Writing Committee et al. Oral thrombin inhibitor dabigatran etexilate vs North American enoxaparin regimen for prevention of venous thromboembolism after knee arthroplasty surgery. J. Arthroplasty 24, 1-9 (2009).
-
(2009)
J. Arthroplasty
, vol.24
, pp. 1-9
-
-
-
15
-
-
34548575058
-
Dabigatran etexilate versus enoxaparin for prevention of venous thromboembolism after total hip replacement: A randomised, double-blind, non-inferiority trial
-
Eriksson, B. I. et al. Dabigatran etexilate versus enoxaparin for prevention of venous thromboembolism after total hip replacement: A randomised, double-blind, non-inferiority trial. Lancet 370, 949-956 (2007).
-
(2007)
Lancet
, vol.370
, pp. 949-956
-
-
Eriksson, B.I.1
-
16
-
-
79953836474
-
Oral dabigatran versus enoxaparin for thromboprophylaxis after primary total hip arthroplasty (RE-NOVATE II): A randomised, double-blind, non-inferiority trial
-
Eriksson, B. I. et al. Oral dabigatran versus enoxaparin for thromboprophylaxis after primary total hip arthroplasty (RE-NOVATE II): A randomised, double-blind, non-inferiority trial. Thromb. Haemost. 105, 721-729 (2011).
-
(2011)
Thromb. Haemost.
, vol.105
, pp. 721-729
-
-
Eriksson, B.I.1
-
17
-
-
71849117615
-
Dabigatran versus warfarin in the treatment of acute venous thromboembolism
-
Schulman, S. et al. Dabigatran versus warfarin in the treatment of acute venous thromboembolism. N. Engl. J. Med. 361, 2342-2352 (2009).
-
(2009)
N. Engl. J. Med.
, vol.361
, pp. 2342-2352
-
-
Schulman, S.1
-
18
-
-
77949882057
-
Insights from the dabigatran versus warfarin trial in patients with venous thromboembolism (the RECOVER trial)
-
Prandoni, P. & Taher, A. Insights from the dabigatran versus warfarin trial in patients with venous thromboembolism (the RECOVER trial). Expert Opin. Pharmacother. 11, 1035-1037 (2010).
-
(2010)
Expert Opin. Pharmacother.
, vol.11
, pp. 1035-1037
-
-
Prandoni, P.1
Taher, A.2
-
19
-
-
84874003257
-
Extended use of dabigatran, warfarin, or placebo in venous thromboembolism
-
Schulman, S. et al. Extended use of dabigatran, warfarin, or placebo in venous thromboembolism. N. Engl. J. Med. 368, 709-718 (2013).
-
(2013)
N. Engl. J. Med.
, vol.368
, pp. 709-718
-
-
Schulman, S.1
-
20
-
-
84873569160
-
Concomitant use of antiplatelet therapy with dabigatran or warfarin in the Randomized Evaluation of Long-Term Anticoagulation Therapy (RE-LY) trial
-
Dans, A. L. et al. Concomitant use of antiplatelet therapy with dabigatran or warfarin in the Randomized Evaluation of Long-Term Anticoagulation Therapy (RE-LY) trial. Circulation 127, 634-640 (2013).
-
(2013)
Circulation
, vol.127
, pp. 634-640
-
-
Dans, A.L.1
-
21
-
-
84857021520
-
Dabigatran association with higher risk of acute coronary events: Meta-analysis of noninferiority randomized controlled trials
-
Uchino, K. & Hernandez, A. V. Dabigatran association with higher risk of acute coronary events: Meta-analysis of noninferiority randomized controlled trials. Arch. Intern. Med. 172, 397-402 (2012).
-
(2012)
Arch. Intern. Med.
, vol.172
, pp. 397-402
-
-
Uchino, K.1
Hernandez, A.V.2
-
22
-
-
77649149260
-
Rivaroxaban: A new oral factor Xa inhibitor
-
Perzborn, E. et al. Rivaroxaban: A new oral factor Xa inhibitor. Arterioscler. Thromb. Vasc. Biol. 30, 376-381 (2010).
-
(2010)
Arterioscler. Thromb. Vasc. Biol.
, vol.30
, pp. 376-381
-
-
Perzborn, E.1
-
23
-
-
84867090302
-
New anticoagulants: A concise review
-
Baumann Kreuziger, L. M., Morton, C. T. & Dries, D. J. New anticoagulants: A concise review. J. Trauma Acute Care Surg. 73, 983-992 (2012).
-
(2012)
J. Trauma Acute Care Surg.
, vol.73
, pp. 983-992
-
-
Baumann Kreuziger, L.M.1
Morton, C.T.2
Dries, D.J.3
-
24
-
-
45949099359
-
Rivaraoxaban versus enoxaparin for thromboprophylaxis after hip arthroplasty
-
Eriksson, B. I. et al. Rivaraoxaban versus enoxaparin for thromboprophylaxis after hip arthroplasty. N. Engl. J. Med. 388, 2765-2775 (2008).
-
(2008)
N. Engl. J. Med.
, vol.388
, pp. 2765-2775
-
-
Eriksson, B.I.1
-
25
-
-
46049106502
-
Extended duration rivaroxaban versus short term enoxaparin for the prevention of VTE after total hip arthroplasty
-
Kakkar, A. K. et al. Extended duration rivaroxaban versus short term enoxaparin for the prevention of VTE after total hip arthroplasty. Lancet 372, 31-39 (2008).
-
(2008)
Lancet
, vol.372
, pp. 31-39
-
-
Kakkar, A.K.1
-
26
-
-
45949103416
-
Rivaroxaban versus enoxaparin for thromboprophylaxis after total knee arthroplasty
-
Lassen, M. R. et al. Rivaroxaban versus enoxaparin for thromboprophylaxis after total knee arthroplasty. N. Engl. J. Med. 358, 2776-2786 (2008).
-
(2008)
N. Engl. J. Med.
, vol.358
, pp. 2776-2786
-
-
Lassen, M.R.1
-
27
-
-
65549169515
-
Rivaroxaban versus enoxaparin for thromboprophylaxis after total knee arthroplasty (RECORD4): A randomized trial
-
Turpie, A. G. et al. Rivaroxaban versus enoxaparin for thromboprophylaxis after total knee arthroplasty (RECORD4): A randomized trial. Lancet 373, 1673-1680 (2009).
-
(2009)
Lancet
, vol.373
, pp. 1673-1680
-
-
Turpie, A.G.1
-
28
-
-
79957619172
-
A systematic review of rivaroxaban versus enoxaparin in the prevention of venous thromboembolism after hip or knee replacement
-
Turun, S. et al. A systematic review of rivaroxaban versus enoxaparin in the prevention of venous thromboembolism after hip or knee replacement. Thromb. Res. 127, 525-534 (2011).
-
(2011)
Thromb. Res.
, vol.127
, pp. 525-534
-
-
Turun, S.1
-
29
-
-
84873514413
-
Rivaroxaban for thromboprophylaxis in acutely ill medical patients
-
Cohen, A. T. et al. Rivaroxaban for thromboprophylaxis in acutely ill medical patients. N. Engl. J. Med. 368, 513-523 (2013).
-
(2013)
N. Engl. J. Med.
, vol.368
, pp. 513-523
-
-
Cohen, A.T.1
-
30
-
-
58149458160
-
Apixaban metabolism and pharmacokinetics after oral administration to humans
-
Raghavan, N. et al. Apixaban metabolism and pharmacokinetics after oral administration to humans. Drug Metab. Dispos. 37, 74-81 (2009).
-
(2009)
Drug Metab. Dispos.
, vol.37
, pp. 74-81
-
-
Raghavan, N.1
-
31
-
-
78650619315
-
Oral rivaroxaban for symptomatic venous thromboembolism
-
EINSTEIN Investigators
-
EINSTEIN Investigators. Oral rivaroxaban for symptomatic venous thromboembolism. N. Engl. J. Med. 363, 2499-2510 (2010).
-
(2010)
N. Engl. J. Med.
, vol.363
, pp. 2499-2510
-
-
-
32
-
-
84859385808
-
Oral rivaroxaban for the treatment of symptomatic pulmonary embolism
-
EINSTEIN-PE Investigators
-
EINSTEIN-PE Investigators. Oral rivaroxaban for the treatment of symptomatic pulmonary embolism. N. Engl. J. Med. 366, 1287-1297 (2012).
-
(2012)
N. Engl. J. Med.
, vol.366
, pp. 1287-1297
-
-
-
33
-
-
84866411664
-
Anticoagulant treatment of pulmonary embolism: Impact and implications of the EINSTEIN PE study
-
Prandoni, P. Anticoagulant treatment of pulmonary embolism: Impact and implications of the EINSTEIN PE study. Eur. J. Haematol. 89, 281-287 (2012).
-
(2012)
Eur. J. Haematol.
, vol.89
, pp. 281-287
-
-
Prandoni, P.1
-
34
-
-
79961199378
-
Oral rivaroxaban after symptomatic venous thromboembolism: The continued treatment study (EINSTEIN-extension study)
-
Romualdi, E., Donadini, M. P. & Ageno, W. Oral rivaroxaban after symptomatic venous thromboembolism: The continued treatment study (EINSTEIN-extension study). Expert Rev. Cardiovasc. Ther. 9, 841-844 (2011).
-
(2011)
Expert Rev. Cardiovasc. Ther.
, vol.9
, pp. 841-844
-
-
Romualdi, E.1
Donadini, M.P.2
Ageno, W.3
-
35
-
-
68249158084
-
Apixaban or enoxaparin for thromboprophylaxis after knee replacement
-
Lassen, M. R. et al. Apixaban or enoxaparin for thromboprophylaxis after knee replacement. N. Engl. J. Med. 361, 594-604 (2009).
-
(2009)
N. Engl. J. Med.
, vol.361
, pp. 594-604
-
-
Lassen, M.R.1
-
36
-
-
77649113258
-
Apixaban versus enoxaparin for thromboprophylaxis after knee replacement (ADVANCE2): A randomised double-blind trial
-
Lassen, M. R. et al. Apixaban versus enoxaparin for thromboprophylaxis after knee replacement (ADVANCE2): A randomised double-blind trial. Lancet 375, 807-815 (2010).
-
(2010)
Lancet
, vol.375
, pp. 807-815
-
-
Lassen, M.R.1
-
37
-
-
78650587760
-
Apixaban versus enoxaparin for thromboprophylaxis after hip replacement
-
Lassen, M. R. et al. Apixaban versus enoxaparin for thromboprophylaxis after hip replacement. N. Engl. J. Med. 363, 2487-2498 (2010).
-
(2010)
N. Engl. J. Med.
, vol.363
, pp. 2487-2498
-
-
Lassen, M.R.1
-
38
-
-
83155193223
-
Apixaban versus enoxaparin for thromboprophylaxis in medically ill patients
-
Goldhaber, S. Z. et al. Apixaban versus enoxaparin for thromboprophylaxis in medically ill patients. N. Engl. J. Med. 365, 2167-2177 (2011).
-
(2011)
N. Engl. J. Med.
, vol.365
, pp. 2167-2177
-
-
Goldhaber, S.Z.1
-
39
-
-
84881115890
-
-
US National Library Of Medicine. ClinicalTrials.gov [online] (2012)
-
US National Library of Medicine. ClinicalTrials.gov [online], http://www.clinicaltrials.gov/ct2/show/NCT00643201 (2012).
-
-
-
-
40
-
-
84873596181
-
Apixaban for extended treatment of venous thromboembolism
-
Agnelli, G. et al. Apixaban for extended treatment of venous thromboembolism. N. Engl. J. Med. 368, 699-708 (2013).
-
(2013)
N. Engl. J. Med.
, vol.368
, pp. 699-708
-
-
Agnelli, G.1
-
41
-
-
77957932391
-
Evaluation of the novel factor Xa inhibitor edoxaban compared with warfarin in patients with atrial fibrillation: Design and rationale for the Effective aNticoaGulation with factor xA next GEneration in Atrial Fibrillation-Thrombolysis In Myocardial Infarction study 48 (ENGAGE AFTIMI 48)
-
Ruff, C. T. et al. Evaluation of the novel factor Xa inhibitor edoxaban compared with warfarin in patients with atrial fibrillation: Design and rationale for the Effective aNticoaGulation with factor xA next GEneration in Atrial Fibrillation-Thrombolysis In Myocardial Infarction study 48 (ENGAGE AFTIMI 48). Am. Heart J. 160, 635-641 (2010).
-
(2010)
Am. Heart J.
, vol.160
, pp. 635-641
-
-
Ruff, C.T.1
-
42
-
-
84880397241
-
Edoxaban for the long-term treatment of venous thromboembolism: Rationale and design of the Hokusai-VTE study
-
Raskob, G. et al. Edoxaban for the long-term treatment of venous thromboembolism: Rationale and design of the Hokusai-VTE study. J. Thromb. Haemost. http://dx.doi.org/10.1111/jth.12230.
-
J. Thromb. Haemost.
-
-
Raskob, G.1
-
43
-
-
84866889137
-
Oral direct factor Xa inhibitors
-
Yeh, C. H., Fredenburgh, J. C. & Weitz, J. I. Oral direct factor Xa inhibitors. Circ. Res. 111, 1069-1078 (2012).
-
(2012)
Circ. Res.
, vol.111
, pp. 1069-1078
-
-
Yeh, C.H.1
Fredenburgh, J.C.2
Weitz, J.I.3
-
44
-
-
84895055241
-
Edoxaban versus enoxaparin for the prevention of venous thromboembolism and bleeding from STARS E3 and STARS J.V [abstract 208]
-
Fuji, T., Fujita, S., Tachibana, S. & Kawai, Y. Edoxaban versus enoxaparin for the prevention of venous thromboembolism and bleeding from STARS E3 and STARS J.V [abstract 208]. Presented at the American Society of Hematology 2011 Annual Meeting.
-
Presented at the American Society of Hematology 2011 Annual Meeting
-
-
Fuji, T.1
Fujita, S.2
Tachibana, S.3
Kawai, Y.4
-
45
-
-
84867588790
-
Oral anticoagulation with edoxaban Focus on current phase III clinical development
-
Ahrens, I. & Bode, C. Oral anticoagulation with edoxaban. Focus on current phase III clinical development. Hamostaseologie 32, 212-215 (2012).
-
(2012)
Hamostaseologie
, vol.32
, pp. 212-215
-
-
Ahrens, I.1
Bode, C.2
-
46
-
-
77956628530
-
Oral direct factor Xa inhibition with edoxaban for thromboprophylaxis after elective total hip replacement: A randomised double-blind dose-response study
-
Raskob, G. et al. Oral direct factor Xa inhibition with edoxaban for thromboprophylaxis after elective total hip replacement: A randomised double-blind dose-response study. Thromb. Haemost. 104, 642-649 (2010).
-
(2010)
Thromb. Haemost.
, vol.104
, pp. 642-649
-
-
Raskob, G.1
-
47
-
-
78149236861
-
A dose-ranging study evaluating the oral factor Xa inhibitor edoxaban for prevention of venous thromboembolism in patients undergoing total knee arthroplasty
-
Fuji, T. et al. A dose-ranging study evaluating the oral factor Xa inhibitor edoxaban for prevention of venous thromboembolism in patients undergoing total knee arthroplasty. J. Thromb. Haemost. 8, 2458-2468 (2010).
-
(2010)
J. Thromb. Haemost.
, vol.8
, pp. 2458-2468
-
-
Fuji, T.1
-
48
-
-
82555175371
-
Venous thromboembolism in patients with symptomatic atherosclerosis
-
Piazza, G. et al. Venous thromboembolism in patients with symptomatic atherosclerosis. Thromb. Haemost. 106, 1095-1102 (2011).
-
(2011)
Thromb. Haemost.
, vol.106
, pp. 1095-1102
-
-
Piazza, G.1
-
49
-
-
84862657225
-
Venous thromboembolism in patients with diabetes mellitus
-
Piazza, G. et al. Venous thromboembolism in patients with diabetes mellitus. Am. J. Med. 125, 709-716 (2011).
-
(2011)
Am. J. Med.
, vol.125
, pp. 709-716
-
-
Piazza, G.1
-
50
-
-
0037431022
-
An association between atherosclerosis and venous thrombosis
-
Prandoni, P. et al. An association between atherosclerosis and venous thrombosis. N. Engl. J. Med. 348, 1435-1441 (2003).
-
(2003)
N. Engl. J. Med.
, vol.348
, pp. 1435-1441
-
-
Prandoni, P.1
-
51
-
-
34250758224
-
Venous thromboembolism and atherosclerosis: Is there a link?
-
Prandoni, P. Venous thromboembolism and atherosclerosis: Is there a link? J. Thromb. Haemost. 5 (Suppl. 1), 270-275 (2007).
-
(2007)
J. Thromb. Haemost.
, vol.5
, Issue.SUPPL. 1
, pp. 270-275
-
-
Prandoni, P.1
-
52
-
-
34547851176
-
Links between arterial and venous disease
-
Prandoni, P. Links between arterial and venous disease. J. Intern. Med. 262, 341-350 (2007).
-
(2007)
J. Intern. Med.
, vol.262
, pp. 341-350
-
-
Prandoni, P.1
-
53
-
-
84873126984
-
2013 ACCF/AHA guideline for the management of ST-elevation myocardial infarction: A report of the American college of cardiology foundation/american heart association task force on practice guidelines
-
O'Gara, P. T. et al. 2013 ACCF/AHA guideline for the management of ST-elevation myocardial infarction: A report of the American College of Cardiology Foundation/American Heart Association task force on practice guidelines. Circulation 127, e362-e425 (2013).
-
(2013)
Circulation
, vol.127
-
-
O'Gara, P.T.1
-
54
-
-
13444278653
-
Ximelagatran vs lowmolecular-weight heparin and warfarin for the treatment of deep vein thrombosis: A randomized trial
-
Fiessinger, J. N. et al. Ximelagatran vs lowmolecular-weight heparin and warfarin for the treatment of deep vein thrombosis: A randomized trial. JAMA 293, 681-689 (2005).
-
(2005)
JAMA
, vol.293
, pp. 681-689
-
-
Fiessinger, J.N.1
-
55
-
-
0345414673
-
Stroke prevention with the oral direct thrombin inhibitor ximelagatran compared with warfarin in patients with nonvalvular atrial fibrillation (SPORTIF III): Randomised controlled trial
-
Olsson, S. B. et al. Stroke prevention with the oral direct thrombin inhibitor ximelagatran compared with warfarin in patients with nonvalvular atrial fibrillation (SPORTIF III): Randomised controlled trial. Lancet 362, 1691-1968 (2003).
-
(2003)
Lancet
, vol.362
, pp. 1691-1968
-
-
Olsson, S.B.1
-
56
-
-
13444309949
-
Ximelagatran vs warfarin for stroke prevention in patients with nonvalvular atrial fibrillation: A randomized trial
-
Albers, G. W. et al. Ximelagatran vs warfarin for stroke prevention in patients with nonvalvular atrial fibrillation: A randomized trial. JAMA 293, 690-698 (2005).
-
(2005)
JAMA
, vol.293
, pp. 690-698
-
-
Albers, G.W.1
-
57
-
-
84865163351
-
Dabigatran and myocardial infarction, drug or class effect: Meta-analysis of randomized trials with oral direct thrombin inhibitors [abstract]
-
Artang, R., Rome, E. & Vidaillet, H. Dabigatran and myocardial infarction, drug or class effect: Meta-analysis of randomized trials with oral direct thrombin inhibitors [abstract]. J. Am. Coll. Cardiol. 59, E571 (2012).
-
(2012)
J. Am. Coll. Cardiol.
, vol.59
-
-
Artang, R.1
Rome, E.2
Vidaillet, H.3
-
58
-
-
84869131278
-
Use of new-generation oral anticoagulant agents in patients receiving antiplatelet therapy after an acute coronary syndrome: Systematic review and meta-analysis of randomized controlled trials
-
Komocsi, A., Vorobcsuk, A., Kehl, D. & Aradi, D. Use of new-generation oral anticoagulant agents in patients receiving antiplatelet therapy after an acute coronary syndrome: Systematic review and meta-analysis of randomized controlled trials. Arch. Intern. Med. 172, 1537-1545 (2012).
-
(2012)
Arch. Intern. Med.
, vol.172
, pp. 1537-1545
-
-
Komocsi, A.1
Vorobcsuk, A.2
Kehl, D.3
Aradi, D.4
-
59
-
-
84876565067
-
A promising drug with a flaw
-
(2 November)
-
Thomas, K. A promising drug with a flaw. The New York Times (2 November 2012).
-
(2012)
The New York Times
-
-
Thomas, K.1
-
60
-
-
80053571188
-
Reversal of rivaroxaban and dabigatran by prothrombin complex concentrate: A randomized, placebo-controlled, crossover study in healthy subjects
-
Eerenberg, E. S. et al. Reversal of rivaroxaban and dabigatran by prothrombin complex concentrate: A randomized, placebo-controlled, crossover study in healthy subjects. Circulation 124, 1573-1579 (2011).
-
(2011)
Circulation
, vol.124
, pp. 1573-1579
-
-
Eerenberg, E.S.1
-
61
-
-
67849126841
-
Managing bleeding in anticoagulated patients with a focus on novel therapeutic agents
-
Crowther, M. A. & Warkentin, T. E. Managing bleeding in anticoagulated patients with a focus on novel therapeutic agents. J. Thromb. Haemost. 7 (Suppl. 1), 107-110 (2009).
-
(2009)
J. Thromb. Haemost.
, vol.7
, Issue.SUPPL. 1
, pp. 107-110
-
-
Crowther, M.A.1
Warkentin, T.E.2
-
62
-
-
84864370719
-
Effect of non-specific reversal agents on anticoagulant activity of dabigatran and rivaroxaban: A randomised crossover ex vivo study in healthy volunteers
-
Marlu, R. et al. Effect of non-specific reversal agents on anticoagulant activity of dabigatran and rivaroxaban: A randomised crossover ex vivo study in healthy volunteers. Thromb. Haemost. 108, 217-224 (2012).
-
(2012)
Thromb. Haemost.
, vol.108
, pp. 217-224
-
-
Marlu, R.1
-
63
-
-
77953168824
-
Dabigatran etexilate-A novel, reversible, oral direct thrombin inhibitor: Interpretation of coagulation assays and reversal of anticoagulant activity
-
van Ryn, J. et al. Dabigatran etexilate-A novel, reversible, oral direct thrombin inhibitor: Interpretation of coagulation assays and reversal of anticoagulant activity. Thromb. Haemost. 103, 1116-1127 (2010).
-
(2010)
Thromb. Haemost.
, vol.103
, pp. 1116-1127
-
-
Van Ryn, J.1
-
64
-
-
84877743192
-
Treatment of bleeding complications when using oral anticoagulants for prevention of strokes
-
Akwaa, F. & Spyropoulos, A. C. Treatment of bleeding complications when using oral anticoagulants for prevention of strokes. Curr. Treat. Options Cardiovasc. Med. http://dx.doi.org/10.1007/s11936-013-0238-5.
-
Curr. Treat. Options Cardiovasc. Med.
-
-
Akwaa, F.1
Spyropoulos, A.C.2
-
65
-
-
84655176578
-
Evaluation of prothrombin complex concentrate and recombinant activated factor VII to reverse rivaroxaban in a rabbit model
-
Godier, A. et al. Evaluation of prothrombin complex concentrate and recombinant activated factor VII to reverse rivaroxaban in a rabbit model. Anesthesiology 116, 94-102 (2012).
-
(2012)
Anesthesiology
, vol.116
, pp. 94-102
-
-
Godier, A.1
-
66
-
-
84895025508
-
PRT064445 but not recombinant FVIIa reverses rivaroxaban induced anticoagulation as measured by reduction in blood loss in a rabbit liver laceration model [abstract 3414]
-
Hollenbach, S. J. et al. PRT064445 but not recombinant FVIIa reverses rivaroxaban induced anticoagulation as measured by reduction in blood loss in a rabbit liver laceration model [abstract 3414]. Presented at the American Society of Hematology 2012 Annual Meeting.
-
Presented at the American Society of Hematology 2012 Annual Meeting
-
-
Hollenbach, S.J.1
-
67
-
-
84859971855
-
Guidance on the emergent reversal of oral thrombin and factor Xa inhibitors
-
Kaatz, S. et al. Guidance on the emergent reversal of oral thrombin and factor Xa inhibitors. Am. J. Hematol. 87 (Suppl. 1), S141-S145 (2012).
-
(2012)
Am. J. Hematol.
, vol.87
, Issue.SUPPL. 1
-
-
Kaatz, S.1
-
68
-
-
77952044405
-
Assessment of laboratory assays to measure rivaroxaban-an oral, direct factor Xa inhibitor
-
Samama, M. M. et al. Assessment of laboratory assays to measure rivaroxaban-an oral, direct factor Xa inhibitor. Thromb. Haemost. 103, 815-825 (2010).
-
(2010)
Thromb. Haemost.
, vol.103
, pp. 815-825
-
-
Samama, M.M.1
-
69
-
-
84865642185
-
New oral anticoagulants: A review of the literature with particular emphasis on patients with impaired renal function
-
Poulsen, B. K., Grove, E. L. & Husted, S. E. New oral anticoagulants: A review of the literature with particular emphasis on patients with impaired renal function. Drugs 72, 1739-1753 (2012).
-
(2012)
Drugs
, vol.72
, pp. 1739-1753
-
-
Poulsen, B.K.1
Grove, E.L.2
Husted, S.E.3
-
70
-
-
77953538367
-
Anticoagulation for mechanical heart valves in patients with and without atrial fibrillation
-
Baber, U., van der Zee, S. & Fuster, V. Anticoagulation for mechanical heart valves in patients with and without atrial fibrillation. Curr. Cardiol. Rep. 12, 133-139 (2010).
-
(2010)
Curr. Cardiol. Rep.
, vol.12
, pp. 133-139
-
-
Baber, U.1
Van Der Zee, S.2
Fuster, V.3
-
71
-
-
84867570927
-
Mechanical valve thrombosis with dabigatran
-
Price, J., Hynes, M., Labinaz, M., Ruel, M. & Boodhwani, M. Mechanical valve thrombosis with dabigatran. J. Am. Coll. Cardiol. 60, 1710-1711 (2012).
-
(2012)
J. Am. Coll. Cardiol.
, vol.60
, pp. 1710-1711
-
-
Price, J.1
Hynes, M.2
Labinaz, M.3
Ruel, M.4
Boodhwani, M.5
-
72
-
-
84862585771
-
A comparison of dabigatran etexilate with warfarin in patients with mechanical heart valves: The randomized, phase II study to evaluate the safety and pharmacokinetics of oral dabigatran etexilate in patients after heart valve replacement (REALIGN)
-
e1
-
Van de Werf, F. et al. A comparison of dabigatran etexilate with warfarin in patients with mechanical heart valves: The randomized, phase II study to evaluate the safety and pharmacokinetics of oral dabigatran etexilate in patients after heart valve replacement (REALIGN). Am. Heart J. 163, 931-937, e1 (2012).
-
(2012)
Am. Heart J.
, vol.163
, pp. 931-937
-
-
Van De Werf, F.1
-
73
-
-
28044439149
-
Trends in the incidence of venous thromboembolism during pregnancy or postpartum: A 30-year population-based study
-
Heit, J. A. et al. Trends in the incidence of venous thromboembolism during pregnancy or postpartum: A 30-year population-based study. Ann. Intern. Med. 143, 697-706 (2005).
-
(2005)
Ann. Intern. Med.
, vol.143
, pp. 697-706
-
-
Heit, J.A.1
-
74
-
-
33646117733
-
Venous thromboembolism during pregnancy and the postpartum period: Incidence, risk factors, and mortality
-
James, A. H., Jamison, M. G., Brancazio, L. R. & Myers, E. R. Venous thromboembolism during pregnancy and the postpartum period: Incidence, risk factors, and mortality. Am. J. Obstet. Gynecol. 194, 1311-1315 (2006).
-
(2006)
Am. J. Obstet. Gynecol.
, vol.194
, pp. 1311-1315
-
-
James, A.H.1
Jamison, M.G.2
Brancazio, L.R.3
Myers, E.R.4
-
75
-
-
0021236578
-
Low molecular weight heparin (PK 10169) does not cross the placenta during the second trimester of pregnancy study by direct fetal blood sampling under ultrasound
-
Forestier, F., Daffos, F. & Capella-Pavlovsky, M. Low molecular weight heparin (PK 10169) does not cross the placenta during the second trimester of pregnancy study by direct fetal blood sampling under ultrasound. Thromb. Res. 34, 557-560 (1984).
-
(1984)
Thromb. Res.
, vol.34
, pp. 557-560
-
-
Forestier, F.1
Daffos, F.2
Capella-Pavlovsky, M.3
-
76
-
-
0024546774
-
Risks to the fetus of anticoagulant therapy during pregnancy
-
Ginsberg, J. S., Hirsh, J., Turner, D. C., Levine, M. N. & Burrows, R. Risks to the fetus of anticoagulant therapy during pregnancy. Thromb. Haemost. 61, 197-203 (1989).
-
(1989)
Thromb. Haemost.
, vol.61
, pp. 197-203
-
-
Ginsberg, J.S.1
Hirsh, J.2
Turner, D.C.3
Levine, M.N.4
Burrows, R.5
-
77
-
-
84873558091
-
Anticoagulant therapy for venous thromboembolism during pregnancy: A systematic review and a meta-analysis of the literature
-
Romualdi, E. et al. Anticoagulant therapy for venous thromboembolism during pregnancy: A systematic review and a meta-analysis of the literature. J. Thromb. Haemost. 11, 270-281 (2013).
-
(2013)
J. Thromb. Haemost.
, vol.11
, pp. 270-281
-
-
Romualdi, E.1
-
78
-
-
84866048530
-
Venous thromboembolism associated with pregnancy and hormonal therapy
-
Jacobsen, A. F. & Sandset, P. M. Venous thromboembolism associated with pregnancy and hormonal therapy. Best Pract. Res. Clin. Haematol. 25, 319-332 (2012).
-
(2012)
Best Pract. Res. Clin. Haematol.
, vol.25
, pp. 319-332
-
-
Jacobsen, A.F.1
Sandset, P.M.2
-
79
-
-
26444511995
-
Pulmonary embolism during and after pregnancy
-
Stone, S. E. & Morris, T. A. Pulmonary embolism during and after pregnancy. Crit. Care Med. 33 (Suppl. 10), S294-S300 (2005).
-
(2005)
Crit. Care Med.
, vol.33
, Issue.SUPPL. 10
-
-
Stone, S.E.1
Morris, T.A.2
-
80
-
-
0034700438
-
Prognosis of cancers associated with venous thromboembolism
-
Sorensen, H. T., Mellemkjaer, L., Olsen, J. H. & Baron, J. A. Prognosis of cancers associated with venous thromboembolism. N. Engl. J. Med. 343, 1846-1850 (2000).
-
(2000)
N. Engl. J. Med.
, vol.343
, pp. 1846-1850
-
-
Sorensen, H.T.1
Mellemkjaer, L.2
Olsen, J.H.3
Baron, J.A.4
-
81
-
-
33644597912
-
Incidence of venous thromboembolism and its effect on survival among patients with common cancers
-
Chew, H. K., Wun, T., Harvey, D., Zhou, H. & White, R. H. Incidence of venous thromboembolism and its effect on survival among patients with common cancers. Arch. Intern. Med. 166, 458-464 (2006).
-
(2006)
Arch. Intern. Med.
, vol.166
, pp. 458-464
-
-
Chew, H.K.1
Wun, T.2
Harvey, D.3
Zhou, H.4
White, R.H.5
-
82
-
-
70350728991
-
Impact of venous thromboembolism and anticoagulation on cancer and cancer survival
-
Kuderer, N. M., Ortel, T. L. & Francis, C. W. Impact of venous thromboembolism and anticoagulation on cancer and cancer survival. J. Clin. Oncol. 27, 4902-11 (2009).
-
(2009)
J. Clin. Oncol.
, vol.27
, pp. 4902-11
-
-
Kuderer, N.M.1
Ortel, T.L.2
Francis, C.W.3
-
83
-
-
84864427506
-
Risk of venous thromboembolism in patients with cancer: A systematic review and meta-analysis
-
Horsted, F., West, J. & Grainge, M. J. Risk of venous thromboembolism in patients with cancer: A systematic review and meta-analysis. PLoS Med. 9, e1001275 (2012).
-
(2012)
PLoS Med
, vol.9
-
-
Horsted, F.1
West, J.2
Grainge, M.J.3
-
84
-
-
84864436154
-
Thrombosis and cancer
-
Young, A. et al. Thrombosis and cancer. Nat. Rev. Clin. Oncol. 9, 437-449 (2012).
-
(2012)
Nat. Rev. Clin. Oncol.
, vol.9
, pp. 437-449
-
-
Young, A.1
-
85
-
-
36849070772
-
American Society of Clinical Oncology guideline: Recommendations for venous thromboembolism prophylaxis and treatment in patients with cancer
-
Lyman, G. H. et al. American Society of Clinical Oncology guideline: Recommendations for venous thromboembolism prophylaxis and treatment in patients with cancer. J. Clin. Oncol. 25, 5490-5505 (2007).
-
(2007)
J. Clin. Oncol.
, vol.25
, pp. 5490-5505
-
-
Lyman, G.H.1
-
86
-
-
0037775584
-
Low-molecular-weight heparin versus a coumarin for the prevention of recurrent venous thromboembolism in patients with cancer
-
Lee, A. Y. et al. Low-molecular-weight heparin versus a coumarin for the prevention of recurrent venous thromboembolism in patients with cancer. N. Engl. J. Med. 349, 146-153 (2003).
-
(2003)
N. Engl. J. Med.
, vol.349
, pp. 146-153
-
-
Lee, A.Y.1
-
87
-
-
84862153740
-
New and old anticoagulants in cancer
-
Verso, M. & Agnelli, G. New and old anticoagulants in cancer. Thromb. Res. 129 (Suppl. 1), S101-S105 (2012).
-
(2012)
Thromb. Res.
, vol.129
, Issue.SUPPL. 1
-
-
Verso, M.1
Agnelli, G.2
-
88
-
-
84873025833
-
International clinical practice guidelines for the treatment and prophylaxis of venous thromboembolism in patients with cancer
-
Farge, D. et al. International clinical practice guidelines for the treatment and prophylaxis of venous thromboembolism in patients with cancer. J. Thromb. Haemost. 11, 56-70 (2013).
-
(2013)
J. Thromb. Haemost.
, vol.11
, pp. 56-70
-
-
Farge, D.1
-
89
-
-
70350726563
-
New antithrombotic drugs: Potential for use in oncology
-
Levine, M. N. New antithrombotic drugs: Potential for use in oncology. J. Clin. Oncol. 27, 4912-4918 (2009).
-
(2009)
J. Clin. Oncol.
, vol.27
, pp. 4912-4918
-
-
Levine, M.N.1
-
90
-
-
60849097858
-
A randomized evaluation of betrixaban, an oral factor Xa inhibitor, for prevention of thromboembolic events after total knee replacement (EXPERT)
-
Turpie, A. G. et al. A randomized evaluation of betrixaban, an oral factor Xa inhibitor, for prevention of thromboembolic events after total knee replacement (EXPERT). Thromb. Haemost. 101, 68-76 (2009).
-
(2009)
Thromb. Haemost.
, vol.101
, pp. 68-76
-
-
Turpie, A.G.1
|