GC-MS-based metabolomics study of the responses to arachidonic acid in Blakeslea trispora

Fungal Genetics and Biology

Volumn 57, Issue , 2013, Pages 33-41

  Hu, Xianmei ^a   Li, Hao ^a   Tang, Pingwah ^a   Sun, Jie ^a   Yuan, Qipeng ^a   Li, Chunfang ^b  

^a BEIJING UNIVERSITY OF CHEMICAL TECHNOLOGY   (China)

^b Beijing Industrial Technician College   (China)

Author keywords

Carotene; Arachidonic acid; Blakeslea trispora; Gas chromatography mass spectrometry; Metabolomics; Multivariate analysis

Indexed keywords

AMINO ACID; ARACHIDONIC ACID; BETA CAROTENE; FATTY ACID;

ARTICLE; BIOCHEMICAL COMPOSITION; BLAKESLEA TRISPORA; CITRIC ACID CYCLE; CONTROLLED STUDY; FERMENTATION MODEL; FUNGAL CELL; GLYCOLYSIS; MASS FRAGMENTOGRAPHY; METABOLITE; METABOLOME; METABOLOMICS; MOLECULAR MODEL; NONHUMAN; PHASE SEPARATION; PRIORITY JOURNAL; ZYGOMYCETES;

Β-CAROTENE; ARACHIDONIC ACID; BLAKESLEA TRISPORA; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; METABOLOMICS; MULTIVARIATE ANALYSIS;

AMINO ACIDS; ARACHIDONIC ACID; BETA CAROTENE; CULTURE MEDIA; FATTY ACIDS; FERMENTATION; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; METABOLOMICS; MUCORALES; PRINCIPAL COMPONENT ANALYSIS;

BLAKESLEA TRISPORA;

EID: 84881103891     PISSN: 10871845     EISSN: 10960937     Source Type: Journal    
DOI: 10.1016/j.fgb.2013.06.002     Document Type: Article

References (30)

1. Black P.N., Faergeman N.J., DiRusso C.C. Long-chain acyl-CoA-dependent regulation of gene expression in bacteria, yeast and mammals. J. Nutr. 2000, 130:305S-309S.
2. Borowitaka L.J., Borowitzka M.A., Moulton T.P. The mass culture of Dunaliella salina for fine chemicals: from laboratory to pilot plant. Hydrobiologia 1984, 116-117:115-121.
3. Boyle S.M., Markham G.D., Hafner E.W., Wright J.M., Tabor H., Tabor C.W. Expression of the cloned genes encoding the putrescine biosynthetic enzymes and methionine adenosyltransferase of Escherichia coli (speA, speB, spec and metK). Gene 1984, 30:129-136.
4. Calder P.C., Yaqoob P., Harvey D.J., Watts A., Newsholme E.A. Incorporation of fatty acids by concanavalin A-stimulated lymphocytes and the effect on fatty acid composition and membrane fluidity. Biochem. J. 1994, 300:509-518.
5. Choi D., Bostock R.M., Avdinshko S., Hildebrand D.F. Lipid derived signals that discriminate wound- and pathogen-responsive isoprenoid pathway in plant: methyl jasmonate and the fungal elicitor arachidonic acid induce different 3-hydroxy-3-methylglutaryl coenzyme A reductase genes and antimicrobial isoprenoids in Solanum tuberosum L. Proc. Natl. Acad. Sci. USA 1994, 9:2329-2333.
6. Choi D., Ward B.L., Bostock R.M. Differential induction and suppression of potato 3-hydroxy-3-methylglutaryl coenzyme A reductase genes in response to Phtophthora infestans and to its elicitor arachidonic acid. Plant Cell 1992, 4:1333-1344.
7. Choudhari S.M., Ananthanarayan L., Singhal R.S. Use of metabolic stimulators and inhibitors for enhanced production of β-carotene and lycopene by Blakeslea trispora NRRL 2895 and 2896. Bioresour. Technol. 2008, 99:3166-3173.
8. Choudhari S., Singhal R. Media optimization for the production of β-carotene by Blakeslea trispora: a statistical approach. Bioresour. Technol. 2008, 99:722-730.
9. Ding M.Z., Li B.Z., Cheng J.S., Yuan Y.J. Metabolome analysis of differential responses of diploid and haploid yeast to ethanol stress. OMICS 2010, 14:553-561.
10. Hosono K. Effect of salt stress on lipid composition and membrane fluidity of the salt-tolerant yeast Zygosaccharomyces rouxii. J. Gen. Microbiol. 1992, 138:91-96.
11. Hu X., Sun J., Yuan Q. Improved β-carotene biosynthesis and gene transcription in Blakeslea trispora with arachidonic acid. Biotechnol. Lett. 2012, 34:2107-2111.
12. Kim S.W., Seo W.T., Park Y.H. Enhanced synthesis of trisporic acid and β-carotene production in Blakeslea trispora by addition of a non-ionic surfactant, Span 20. J. Ferment. Bioeng. 1997, 84:330-332.
13. Kinross J.M., Alkhamesi N., Barton R.H., Silk D.B., Yap I.K.S., Darzi A.W., Holmes E., Nicholson K. Global metabolic phenotyping in an experimental laparotomy model of surgical trauma. J. Proteome Res. 2011, 10:277-287.
14. Li H., Ma M.L., Luo S., Zhang R.M., Han P., Hu W. Metabolic responses to ethanol in Saccharomyces cerevisiae using a gas chromatography tandem mass spectrometry-based metabolomics approach. Int. J. Biochem. Cell Biol. 2012, 44:1087-1096.
15. Mantzouridou F., Tsimidou M.Z., Roukas T. Performance of crude olive pomace oil and soybean oil during carotenoid production by Blakeslea trispora in submerged fermentation. J. Agric. Food Chem. 2006, 54:2575-2581.
16. Mendoza H., Martel A., Jiménez del Río M., García Reina G. Oleic acid is the main fatty acid related with carotenogenisis in Dunaliella salina. J. Appl. Phycol. 1999, 11:15-19.
17. Michaud M.R., Benoit J.B., Lopez-Martinez G., Elnitsky M.A., Lee R.E., Denlinger D.L. Metabolomics reveals unique and shared metabolic changes in response to heat shock, freezing and desiccation in the Antarctic midge, Belgica antarctica. J. Insect. Physiol. 2008, 54:645-655.
18. Nanou K., Roukas T. Oxidative stress response and morphological changes of Blakeslea trispora induced by butylated hydroxytoluene during carotene production. Appl. Biochem. Biotechnol. 2010, 160:2415-2423.
19. Papaioannou E.H., Liakopoulou-Kyriakides M. Substrate contribution on carotenoids production in Blakeslea trispora cultivations. Food Bioprod. Process 2010, 88:305-311.
20. Rodríguez-Concepción M., Gruissem W. Arachidonic acid alters tomato HMG expression and fruit growth and induces 3-hydroxy-3-methylglutaryl coenzyme A reductase-independent lycopene accumulation. Plant Physiol. 1999, 119:41-48.
21. Shaibe E., Metzer E., Halpern Y.S. Metabolic pathway for the utilization of l-arginine, l-ornithine, agmatine, and putrescine as nitrogen sources in Escherichia coli K-12. J. Bacteriol. 1985, 163:933-937.
22. Stermer B.A., Bostock R.M. Involvement of 3-hydroxy-3-methylglutaryl coenzyme A reductase in the regulation of sesquiterpenoid phytoalexin synthesis in potato. Plant Physiol. 1987, 84:404-408.
23. Sun J., Li H., Yuan Q. Metabolic regulation of trisporic acid on Blakeslea trispora revealed by a GC-MS-based metabolomic approach. PLoS ONE 2012, 7(9):e46110. 10.1371/journal.pone.0046110.
24. Sun Y., Yuan Q.P., Vriesekoop F. Effect of two ergosterol biosynthesis inhibitors on lycopene production by Blakeslea trispora. Process Biochem. 2007, 42:1460-1464.
25. Wang G.Y., Keasling J.D. Amplification of HMG-CoA reductase production enhances carotenoid accumulation in Neurospora crassa. Metab. Eng. 2002, 4:193-201.
26. Woo H.M., Kim K.M., Choi M.H., Jung B.H., Lee J., Kong G., Nam S.J., Kim S., Bai S.W., Chung B.C. Mass spectrometry based metabolomic approaches in urinary biomarker study of women's cancers. Clin. Chim. Acta 2009, 400:63-69.
27. Wöstemeyer J. Strain-dependent variation in ribosomal DNA arrangement in Absidia glauca. Eur. J. Biochem. 1985, 146:443-448.
28. Xu F., Yuan Q.P., Dong H.R. Determination of lycopene and β-carotene by high-performance liquid chromatography using sudan I as internal standard. J. Chromatogr. B 2006, 838:44-49.
29. Xu F., Yuan Q.P., Zhu Y. Improved production of lycopene and β-carotene by Blakeslea trispora with oxygen-vectors. Process Biochem. 2007, 42:289-293.
30. Young L.Y., Hull C.M., Heitman J. Disruption of ergosterol biosynthesis confers resistance to amphotericin B in Candida iusitaniae. Antimicrob. Agents Chemother. 2003, 47:2717-2724.