Serum from minimal change patients in relapse increases CD80 expression in cultured podocytes

Pediatric Nephrology

Volumn 28, Issue 9, 2013, Pages 1803-1812

  Ishimoto, Takuji ^a   Cara Fuentes, Gabriel ^b   Wang, Heiman ^b   Shimada, Michiko ^a   Wasserfall, Clive H ^c   Winter, William E ^c   Rivard, Christopher J ^a   Araya, Carlos E ^b   Saleem, Moin A ^d   Mathieson, Peter W ^d   Johnson, Richard J ^a   Garin, Eduardo H ^b  

^a UNIVERSITY OF COLORADO   (United States)

^b UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF FLORIDA   (United States)

^d UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

CD80; Minimal change disease; Nephrotic syndrome

Indexed keywords

B7 ANTIGEN; INTERLEUKIN 13; INTERLEUKIN 3; INTERLEUKIN 8; PREDNISONE; SERUM ALBUMIN;

ALBUMIN BLOOD LEVEL; ANTIGEN EXPRESSION; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GLOMERULUS BASEMENT MEMBRANE; HUMAN; HUMAN CELL; HUMAN TISSUE; LIMIT OF DETECTION; MALE; PODOCYTE; PRIORITY JOURNAL; PROTEIN SECRETION; PROTEIN URINE LEVEL; RELAPSE; REMISSION;

EID: 84881074341     PISSN: 0931041X     EISSN: 1432198X     Source Type: Journal    
DOI: 10.1007/s00467-013-2498-4     Document Type: Article

References (26)

1. International Study of Kidney Disease in Children (1978) Nephrotic syndrome in children: Prediction of histopathology from clinical and laboratory characteristics at time of diagnosis. A Report of the International Study of Kidney Disease in Children. Kidney Int 13:159-165
2. Shalhoub RJ (1974) Pathogenesis of lipoid nephrosis: A disorder of T-cell function. Lancet 2:556-560
3. Koyama A, Fujisaki M, Kobayashi M, Igarashi M, Narita M (1991) A glomerular permeability factor produced by human T-cell hybridomas. Kidney Int 40:453-460
4. Garin EH, Laflam PF, Muffly K (2006) Proteinuria and fusion of podocyte foot processes in rats after infusion of cytokine from patients with idiopathic minimal lesion nephrotic syndrome. Nephron Exp Nephrol 102:e105-112
5. Greenwald RJ, Freeman GJ, Sharpe AH (2005) The B7 family revisited. Annu Rev Immunol 23:515-548
6. Reiser J, von Gersdorff G, Loos M, Oh L, Asanuma K, Giardino L, Rastaldi MP, Calvaresi N, Watanabe H, Schwarz K, Faul C, Kretzler M, Davidson A, Sugimoto H, Kalluri R, Sharpe AH, Kreidberg JA, Mundel P (2004) Induction of B7-1 in podocytes is associated with nephrotic syndrome. J Clin Invest 113:1390-1397
7. Garin EH, Mu W, Arthur JM, Rivard CJ, Araya CE, Shimada M, Johnson RJ (2010) Urinary CD80 is elevated in minimal change disease but not in focal segmental glomerulosclerosis. Kidney Int 78:296-302
8. Garin EH, Diaz LN, Mu W, Wasserfall C, Araya C, Segal M, Johnson RJ (2009) Urinary CD80 excretion increases in idiopathic minimal-change disease. J Am Soc Nephrol 20:260-266
9. Shimada M, Araya C, Rivard C, Ishimoto T, Johnson RJ, Garin EH (2011) Minimal change disease: A "Two hit" podocyte immune disorder? Pediatr Nephrol 26:645-649
10. International Study of Kidney Disease in Children (1981) Primary nephrotic syndrome in children: Clinical significance of histopathologic variants of minimal change and of diffuse mesangial hypercellularity. A Report of the International Study of Kidney Disease in Children. Kidney Int 20:765-771
11. Garin EH, Boggs KP (1987) Effect of peripheral blood mononuclear cells from patients with nephrotic syndrome on uptake of 35sulfate by glomerular basement membrane. Int J Pediatr Nephrol 6:189-194
12. Saleem MA, O'Hare MJ, Reiser J, Coward RJ, Inward CD, Farren T, Xing CY, Ni L, Mathieson PW, Mundel P (2002) A conditionally immortalized human podocyte cell line demonstrating nephrin and podocin expression. J Am Soc Nephrol 13:630-638
13. Blau EB, Haas JE (1973) Glomerular sialic acid and proteinuria in human renal disease. Lab Invest 28:477-481
14. Garin EH, Boggs KP (1985) Effect of supernatants from nephrotic peripheral blood mononuclear cells on 35sulfate incorporation in rat glomerular basement membrane. Pediatr Res 19:836-840
15. Mundel P, Shankland SJ (2002) Podocyte biology and response to injury. J Am Soc Nephrol 13:3005-3015
16. Chiron D, Pellat-Deceunynck C, Amiot M, Bataille R, Jego G (2009) TLR3 ligand induces NF-{kappa}B activation and various fates of multiple myeloma cells depending on IFN-{alpha} production. J Immunol 182:4471-4478
17. Yu H, Ha T, Liu L, Wang X, Gao M, Kelley J, Kao R, Williams D, Li C (2012) Scavenger receptor A (SR-A) is required for LPS-induced TLR4 mediated NF-κB activation in macrophages. Biochim Biophys Acta 1823:1192-1198
18. Shimada M, Ishimoto T, Lee PY, Lanaspa MA, Rivard CJ, Roncal-Jimenez CA, Wymer DT, Yamabe H, Mathieson PW, Saleem MA, Garin EH, Johnson RJ (2012) Toll-like receptor 3 ligands induce CD80 expression in human podocytes via an NF-kappaB-dependent pathway. Nephrol Dial Transplant 27:81-89
19. Yap HK, Cheung W, Murugasu B, Sim SK, Seah CC, Jordan SC (1999) Th1 and Th2 cytokine mRNA profiles in childhood nephrotic syndrome: Evidence for increased IL-13 mRNA expression in relapse. J Am Soc Nephrol 10:529-537
20. Lai KW, Wei CL, Tan LK, Tan PH, Chiang GS, Lee CG, Jordan SC, Yap HK (2007) Overexpression of interleukin-13 induces minimal change-like nephropathy in rats. J Am Soc Nephrol 18:1476-1485
21. Cheung W, Wei CL, Seah CC, Jordan SC, Yap HK (2004) Atopy, serum IgE, and interleukin-13 in steroid-responsive nephrotic syndrome. Pediatr Nephrol 19:627-632
22. Garin EH, West L, Zheng W (2000) Interleukin-8 alters glomerular heparan sulfate glycosaminoglycan chain size and charge in rats. Pediatr Nephrol 14:284-287
23. Garin EH, Blanchard DK, Matsushima K, Djeu JY (1994) IL-8 production by peripheral blood mononuclear cells in nephrotic patients. Kidney Int 45:1311-1317
24. Reiser J, Mundel P (2004) Danger signaling by glomerular podocytes defines a novel function of inducible B7-1 in the pathogenesis of nephrotic syndrome. J Am Soc Nephrol 15:2246-2248
25. MacDonald NE, Wolfish N, McLaine P, Phipps P, Rossier E (1986) Role of respiratory viruses in exacerbations of primary nephrotic syndrome. J Pediatr 108:378-382
26. Xatzipsalti M, Kyrana S, Tsolia M, Psarras S, Bossios A, Laza-Stanca V, Johnston SL, Papadopoulos NG (2005) Rhinovirus viremia in children with respiratory infections. Am J Respir Crit Care Med 172:1037-1040