Of mice and men-warning: Intact versus castrated adult male mice as xenograft hosts are equivalent to hypogonadal versus abiraterone treated aging human males, respectively

Prostate

Volumn 73, Issue 12, 2013, Pages 1316-1325

  Michiel Sedelaar, J P ^a,b   Dalrymple, Susan S ^a   Isaacs, John T ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

eugonadal levels; free testosterone; hypogonadal levels; mice versus humans; serum total testosterone

Indexed keywords

ABIRATERONE; ANDROGEN; CYTOCHROME P450; KETOCONAZOLE; TESTOSTERONE;

ADULT; ADVANCED CANCER; AGED; AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL; CANCER SURGERY; CASTRATED MALE; CASTRATION RESISTANT PROSTATE CANCER; COMPARATIVE STUDY; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; HYPOGONADISM; MALE; MICROENVIRONMENT; MOUSE; NONHUMAN; ORCHIECTOMY; PRIORITY JOURNAL; PROSTATE WEIGHT; PROTEIN EXPRESSION; TESTOSTERONE BLOOD LEVEL; TUMOR XENOGRAFT;

EUGONADAL LEVELS; FREE TESTOSTERONE; HYPOGONADAL LEVELS; MICE VERSUS HUMANS; SERUM TOTAL TESTOSTERONE;

ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; AGING; ANDROSTENOLS; ANIMALS; CELL LINE, TUMOR; HUMANS; HYPOGONADISM; MALE; MICE; MICE, INBRED C57BL; MICE, NUDE; MIDDLE AGED; ORCHIECTOMY; TESTOSTERONE; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84881051713     PISSN: 02704137     EISSN: 10970045     Source Type: Journal    
DOI: 10.1002/pros.22677     Document Type: Article

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