Prognostic value of alpha-methyl CoA racemase (AMACR) expression in renal cell carcinoma

World Journal of Urology

Volumn 31, Issue 4, 2013, Pages 847-853

  Eichelberg, Christian ^a   Minner, Sarah ^a   Isbarn, Hendrik ^a   Burandt, Eike ^a   Terracciano, Luigi ^b   Moch, Holger ^c   Kell, Alexandra ^a   Heuer, Roman ^a   Chun, Felix K ^a   Sauter, Guido ^a   Fisch, Margit ^a   Tennstedt, Pierre ^a  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^b UNIVERSITY HOSPITAL BASEL   (Switzerland)

^c UNIVERSITY HOSPITAL ZURICH   (Switzerland)

Author keywords

Alpha methyl CoA racemase (AMACR); P504 s; Papillary renal carcinoma; Prognosis; Renal carcinoma subtyping

Indexed keywords

2 METHYLACYL COENZYME A RACEMASE; ALPHA-METHYLACYL-COA RACEMASE; ISOMERASE; TUMOR MARKER;

ARTICLE; BIOSYNTHESIS; CANCER STAGING; COHORT ANALYSIS; FOLLOW UP; GENE EXPRESSION REGULATION; GENETICS; HUMAN; KAPLAN MEIER METHOD; KIDNEY CARCINOMA; KIDNEY TUMOR; METABOLISM; MORTALITY; PREDICTIVE VALUE; PROGNOSIS; RETROSPECTIVE STUDY; SURVIVAL RATE;

CARCINOMA, RENAL CELL; COHORT STUDIES; FOLLOW-UP STUDIES; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; KAPLAN-MEIER ESTIMATE; KIDNEY NEOPLASMS; NEOPLASM STAGING; PREDICTIVE VALUE OF TESTS; PROGNOSIS; RACEMASES AND EPIMERASES; RETROSPECTIVE STUDIES; SURVIVAL RATE; TUMOR MARKERS, BIOLOGICAL;

EID: 84881048862     PISSN: 07244983     EISSN: 14338726     Source Type: Journal    
DOI: 10.1007/s00345-011-0783-z     Document Type: Article

References (28)

1. Ferlay J, Parkin DM, Steliarova-Foucher E (2010) Estimates of cancer incidence, mortality in Europe in 2008. Eur J Cancer 46(4): 765-781.
2. Eble JN, Sauter G, Epstein JI, Sesterhenn IA (2004) Pathology and genetics of tumours of the urinary system and male genital organs. World Health Organization Classification of Tumours. IARC Press, Lyon, p 7.
3. Thoenes W, Storkel S, Rumpelt HJ, Moll R, Baum HP, Werner S (1988) Chromophobe cell renal carcinoma and its variants-a report on 32 cases. J Pathol 155(4): 277-287.
4. Amin MB, Tamboli P, Javidan J, Stricker H, de-Peralta Venturina M, Deshpande A, Menon M (2002) Prognostic impact of histologic subtyping of adult renal epithelial neoplasms: an experience of 405 cases. Am J Surg Pathol 26(3): 281-291.
5. Schmidbauer J, Remzi M, Memarsadeghi M, Haitel A, Klingler HC, Katzenbeisser D, Wiener H, Marberger M (2008) Diagnostic accuracy of computed tomography-guided percutaneous biopsy of renal masses. Eur Urol 53(5): 1003-1011.
6. Allory Y, Bazille C, Vieillefond A, Molinié V, Cochand-Priollet B, Cussenot O, Callard P, Sibony M (2008) Profiling and classification tree applied to renal epithelial tumours. Histopathology 52(2): 158-166.
7. Molinie V, Balaton A, Rotman S, Mansouri D, De Pinieux I, Homsi T, Guillou L (2006) Alpha-methyl CoA racemase expression in renal cell carcinomas. Hum Pathol 37(6): 698-703.
8. Tretiakova MS, Sahoo S, Takahashi M, Turkyilmaz M, Vogelzang NJ, Lin F, Krausz T, Teh BT, Yang XJ (2004) Expression of alpha-methylacyl-CoA racemase in papillary renal cell carcinoma. Am J Surg Pathol 28(1): 69-76.
9. Lin F, Brown RE, Shen T, Yang XJ, Schuerch C (2004) Immunohistochemical detection of P504S in primary and metastatic renal cell carcinomas. Appl Immunohistochem Mol Morphol 12(2): 153-159.
10. Rubin MA, Bismar TA, Andren O, Mucci L, Kim R, Shen R, Ghosh D, Wei JT, Chinnaiyan AM, Adami HO, Kantoff PW, Johansson JE (2005) Decreased alpha-methylacyl CoA racemase expression in localized prostate cancer is associated with an increased rate of biochemical recurrence and cancer-specific death. Cancer Epidemiol Biomarkers Prev 14(6): 1424-1432.
11. Anne L, Martin RW, David SK, Philip BP, Laura HT, Hikmat A-A, Sun Hoo P, Jose GG, Larissa T, Wong WD, William LG, Jinru S (2007) Differential expression of alpha-methylacyl-coenzyme A racemase in colorectal carcinoma bears clinical and pathologic significance. Hum Pathol 38(6): 850.
12. Moch H, Schraml P, Bubendorf L, Mirlacher M, Kononen J, Gasser T, Mihatsch MJ, Kallioniemi OP, Sauter G (1999) High-throughput tissue microarray analysis to evaluate genes uncovered by cDNA microarray screening in renal cell carcinoma. Am J Pathol 154(4): 981-986.
13. Mirlacher M, Simon R (2010) Recipient block TMA technique. Methods Mol Biol 664: 37-44.
14. Went P, Dirnhofer S, Salvisberg T, Amin MB, Lim SD, Diener PA, Moch H (2005) Expression of epithelial cell adhesion molecule (EpCam) in renal epithelial tumors. Am J Surg Pathol 29(1): 83-88.
15. Rubin MA, Zhou M, Dhanasekaran SM, Varambally S, Barrette TR, Sanda MG, Pienta KJ, Ghosh D, Chinnaiyan AM (2002) Alpha-methylacyl coenzyme: a racemase as a tissue biomarker for prostate cancer. Jama 287(13): 1662-1670.
16. Jiang Z, Wu CL, Woda BA, Dresser K, Xu J, Fanger GR, Yang XJ (2002) P504S/alpha-methylacyl-CoA racemase: a useful marker for diagnosis of small foci of prostatic carcinoma on needle biopsy. Am J Surg Pathol 26(9): 1169-1174.
17. Ferdinandusse S, Denis S, IJlst L, Dacremont G, Waterham HR, Wanders RJ (2000) Subcellular localization and physiological role of alpha-methylacyl-CoA racemase. J Lipid Res 41(11): 1890-1896.
18. Mistry T, Digby JE, Desai KM, Randeva HS (2007) Obesity and prostate cancer: a role for adipokines. Eur Urol 52(1): 46-53. doi: 10. 1016/j. eururo. 2007. 03. 054.
19. Key TJ, Allen NE, Spencer EA, Travis RC (2002) The effect of diet on risk of cancer. Lancet 360(9336): 861-868. doi: 10. 1016/S0140-6736(02)09958-0.
20. Bartsch H, Nair J, Owen RW (1999) Dietary polyunsaturated fatty acids and cancers of the breast and colorectum: emerging evidence for their role as risk modifiers. Carcinogenesis 20(12): 2209-2218.
21. Jiang Z, Fanger GR, Woda BA, Banner BF, Algate P, Dresser K, Xu J, Chu PG (2003) Expression of [alpha]-methylacyl-coa racemase (p504s) in various malignant neoplasms and normal tissues: a study of 761 cases. Hum Pathol 34(8): 792.
22. Zhou M, Chinnaiyan AM, Kleer CG, Lucas PC, Rubin MA (2002) Alpha-methylacyl-CoA racemase: a novel tumor marker over-expressed in several human cancers and their precursor lesions. Am J Surg Pathol 26(7): 926-931.
23. Ljungberg B, Cowan NC, Hanbury DC, Hora M, Kuczyk MA, Merseburger AS, Patard JJ, Mulders PF, Sinescu IC (2010) EAU guidelines on renal cell carcinoma: the 2010 update. Eur Urol 58(3): 398-406.
24. Parker AS, Lohse CM, Cheville JC, Thiel DD, Leibovich BC, Blute ML (2006) Greater body mass index is associated with better pathologic features and improved outcome among patients treated surgically for clear cell renal cell carcinoma. Urology 68(4): 741-746.
25. Schrader AJ, Rustemeier J, Rustemeier JC, Timmesfeld N, Varga Z, Hegele A, Olbert PJ, Hofmann R (2009) Overweight is associated with improved cancer-specific survival in patients with organ-confined renal cell carcinoma. J Cancer Res Clin Oncol 135(12): 1693-1699.
26. Ljungberg B, Hanbury DC, Kuczyk MA, Merseburger AS, Mulders PF, Patard JJ, Sinescu IC (2007) Renal cell carcinoma guideline. Eur Urol 51(6): 1502-1510.
27. Rubin MA, Zhou M, Dhanasekaran SM, Varambally S, Barrette TR, Sanda MG, Pienta KJ, Ghosh D, Chinnaiyan AM (2002) Alpha-methylacyl coenzyme: a racemase as a tissue biomarker for prostate cancer. Jama 287(13): 1662-1670.
28. Kuefer R, Varambally S, Zhou M, Lucas PC, Loeffler M, Wolter H, Mattfeldt T, Hautmann RE, Gschwend JE, Barrette TR, Dunn RL, Chinnaiyan AM, Rubin MA (2002) Alpha-methylacyl-CoA racemase: expression levels of this novel cancer biomarker depend on tumor differentiation. Am J Pathol 161(3): 841-848.