-
1
-
-
0020083795
-
Interstitial fluid pressure in DMBA-induced rat mammary tumours
-
Wiig H, Tveit E, Hultborn R, Reed RK, and Weiss L (1982). Interstitial fluid pressure in DMBA-induced rat mammary tumours. Scan J Clin Lab Invest 42, 159-164.
-
(1982)
Scan J Clin Lab Invest
, vol.42
, pp. 159-164
-
-
Wiig, H.1
Tveit, E.2
Hultborn, R.3
Reed, R.K.4
Weiss, L.5
-
2
-
-
0028470454
-
Barriers to drug delivery in solid tumors
-
Jain RK (1994). Barriers to drug delivery in solid tumors. Sci Am 271, 58-65.
-
(1994)
Sci Am
, vol.271
, pp. 58-65
-
-
Jain, R.K.1
-
3
-
-
0031747280
-
The next frontier of molecular medicine: Delivery of therapeutics
-
Jain RK (1998). The next frontier of molecular medicine: delivery of therapeutics. Nat Med 4, 655-657.
-
(1998)
Nat Med
, vol.4
, pp. 655-657
-
-
Jain, R.K.1
-
4
-
-
4944266313
-
High interstitial fluid pressure-an obstacle in cancer therapy
-
Heldin CH, Rubin K, Pietras K, and Östman A (2004). High interstitial fluid pressure-an obstacle in cancer therapy. Nat Rev Cancer 4, 806-813.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 806-813
-
-
Heldin, C.H.1
Rubin, K.2
Pietras, K.3
Östman, A.4
-
5
-
-
0032738258
-
Interstitial fluid pressure and capillary diameter distribution in human melanoma xenografts
-
Tufto I and Rofstad EK (1999). Interstitial fluid pressure and capillary diameter distribution in human melanoma xenografts. Microvasc Res 58, 205-214.
-
(1999)
Microvasc Res
, vol.58
, pp. 205-214
-
-
Tufto, I.1
Rofstad, E.K.2
-
6
-
-
0034648765
-
Angiogenesis in cancer and other diseases
-
Carmeliet P and Jain RK (2000). Angiogenesis in cancer and other diseases. Nature 407, 249-257.
-
(2000)
Nature
, vol.407
, pp. 249-257
-
-
Carmeliet, P.1
Jain, R.K.2
-
7
-
-
0034662608
-
Absence of functional lymphatics within a murine sarcoma: A molecular and functional evaluation
-
Leu AJ, Berk DA, Lymboussaki A, Alitalo K, and Jain RK (2000). Absence of functional lymphatics within a murine sarcoma: a molecular and functional evaluation. Cancer Res 60, 4324-4327.
-
(2000)
Cancer Res
, vol.60
, pp. 4324-4327
-
-
Leu, A.J.1
Berk, D.A.2
Lymboussaki, A.3
Alitalo, K.4
Jain, R.K.5
-
8
-
-
0023219734
-
Transport of molecules in the tumor interstitium: A review
-
Jain RK (1987). Transport of molecules in the tumor interstitium: a review. Cancer Res 47, 3039-3051.
-
(1987)
Cancer Res
, vol.47
, pp. 3039-3051
-
-
Jain, R.K.1
-
9
-
-
0035816177
-
Delivery of molecular medicine to solid tumors: Lessons from in vivo imaging of gene expression and function
-
Jain RK (2001). Delivery of molecular medicine to solid tumors: lessons from in vivo imaging of gene expression and function. J Control Release 74, 7-25.
-
(2001)
J Control Release
, vol.74
, pp. 7-25
-
-
Jain, R.K.1
-
10
-
-
34047260282
-
Effect of vascular normalization by antiangiogenic therapy on interstitial hypertension, peritumor edema, and lymphatic metastasis: Insights from a mathematical model
-
Jain RK, Tong RT, and Munn LL (2007). Effect of vascular normalization by antiangiogenic therapy on interstitial hypertension, peritumor edema, and lymphatic metastasis: insights from a mathematical model. Cancer Res 67, 2729-2735.
-
(2007)
Cancer Res
, vol.67
, pp. 2729-2735
-
-
Jain, R.K.1
Tong, R.T.2
Munn, L.L.3
-
11
-
-
1542320497
-
Pathology: Cancer cells compress intratumour vessels
-
Padera TP, Stoll BR, Tooredman JB, Capen D, di Tomaso E, and Jain RK (2004). Pathology: cancer cells compress intratumour vessels. Nature 427, 695.
-
(2004)
Nature
, vol.427
, pp. 695
-
-
Padera, T.P.1
Stoll, B.R.2
Tooredman, J.B.3
Capen, D.4
Di, T.E.5
Jain, R.K.6
-
12
-
-
3042826827
-
Peritumor lymphatics induced by vascular endothelial growth factor-c exhibit abnormal function
-
Isaka N, Padera TP, Hagendoorn J, Fukumura D, and Jain RK (2004). Peritumor lymphatics induced by vascular endothelial growth factor-c exhibit abnormal function. Cancer Res 64, 4400-4404.
-
(2004)
Cancer Res
, vol.64
, pp. 4400-4404
-
-
Isaka, N.1
Padera, T.P.2
Hagendoorn, J.3
Fukumura, D.4
Jain, R.K.5
-
13
-
-
0037036136
-
Lymphatic metastasis in the absence of functional intratumor lymphatics
-
Padera TP, Kadambi A, di Tomaso E, Carreira CM, Brown EB, Boucher Y, Choi NC, Mathisen D, Wain J, Mark EJ, et al. (2002). Lymphatic metastasis in the absence of functional intratumor lymphatics. Science 296, 1883-1886.
-
(2002)
Science
, vol.296
, pp. 1883-1886
-
-
Padera, T.P.1
Kadambi, A.2
Di, T.E.3
Carreira, C.M.4
Brown, E.B.5
Boucher, Y.6
Choi, N.C.7
Mathisen, D.8
Wain, J.9
Mark, E.J.10
-
14
-
-
33646464845
-
Lowering of tumor interstitial fluid pressure reduces tumor cell proliferation in a xenograft tumor model
-
Hofmann M, Guschel M, Bernd A, Bereiter-Hahn J, Kaufmann R, Tandi C, Wiig H, and Kippenberger S (2006). Lowering of tumor interstitial fluid pressure reduces tumor cell proliferation in a xenograft tumor model. Neoplasia 8, 89-95.
-
(2006)
Neoplasia
, vol.8
, pp. 89-95
-
-
Hofmann, M.1
Guschel, M.2
Bernd, A.3
Bereiter-Hahn, J.4
Kaufmann, R.5
Tandi, C.6
Wiig, H.7
Kippenberger, S.8
-
15
-
-
34250885728
-
Long-term lowering of tumour interstitial fluid pressure reduces Ki-67 expression
-
Hofmann M, Schultz M, Bernd A, Bereiter-Hahn J, Kaufmann R, and Kippenberger S (2007). Long-term lowering of tumour interstitial fluid pressure reduces Ki-67 expression. J Biomech 40, 2324-2329.
-
(2007)
J Biomech
, vol.40
, pp. 2324-2329
-
-
Hofmann, M.1
Schultz, M.2
Bernd, A.3
Bereiter-Hahn, J.4
Kaufmann, R.5
Kippenberger, S.6
-
16
-
-
67650469703
-
Increased plasma colloid osmotic pressure facilitates the uptake of therapeutic macromolecules in a xenograft tumor model
-
Hofmann M, McCormack E, Mujic M, Rossberg M, Bernd A, Bereiter-Hahn J, Gjertsen BT, Wiig H, and Kippenberger S (2009). Increased plasma colloid osmotic pressure facilitates the uptake of therapeutic macromolecules in a xenograft tumor model. Neoplasia 11, 812-822.
-
(2009)
Neoplasia
, vol.11
, pp. 812-822
-
-
Hofmann, M.1
McCormack, E.2
Mujic, M.3
Rossberg, M.4
Bernd, A.5
Bereiter-Hahn, J.6
Gjertsen, B.T.7
Wiig, H.8
Kippenberger, S.9
-
17
-
-
0032890361
-
Structure, expression and receptor-binding properties of novel vascular endothelial growth factors
-
Eriksson U and Alitalo K (1999). Structure, expression and receptor-binding properties of novel vascular endothelial growth factors. Curr Top Microbiol Immunol 237, 41-57.
-
(1999)
Curr Top Microbiol Immunol
, vol.237
, pp. 41-57
-
-
Eriksson, U.1
Alitalo, K.2
-
18
-
-
0032890051
-
Vascular endothelial growth factor: Molecular and biological aspects
-
Ferrara N (1999). Vascular endothelial growth factor: molecular and biological aspects. Curr Top Microbiol Immunol 237, 1-30.
-
(1999)
Curr Top Microbiol Immunol
, vol.237
, pp. 1-30
-
-
Ferrara, N.1
-
19
-
-
0030453355
-
VEGF-C receptor binding and pattern of expression with VEGFR-3 suggests a role in lymphatic vascular development
-
Kukk E, Lymboussaki A, Taira S, Kaipainen A, Jeltsch M, Joukov V, and Alitalo K (1996). VEGF-C receptor binding and pattern of expression with VEGFR-3 suggests a role in lymphatic vascular development. Development 122, 3829-3837.
-
(1996)
Development
, vol.122
, pp. 3829-3837
-
-
Kukk, E.1
Lymboussaki, A.2
Taira, S.3
Kaipainen, A.4
Jeltsch, M.5
Joukov, V.6
Alitalo, K.7
-
20
-
-
0033607817
-
Vascular endo-thelial growth factor (VEGF) and VEGF-C show overlapping binding sites in embryonic endothelia and distinct sites in differentiated adult endothelia
-
Lymboussaki A, Olofsson B, Eriksson U, and Alitalo K (1999). Vascular endo-thelial growth factor (VEGF) and VEGF-C show overlapping binding sites in embryonic endothelia and distinct sites in differentiated adult endothelia. Circ Res 85, 992-999.
-
(1999)
Circ Res
, vol.85
, pp. 992-999
-
-
Lymboussaki, A.1
Olofsson, B.2
Eriksson, U.3
Alitalo, K.4
-
21
-
-
0030973506
-
Hyperplasia of lymphatic vessels in VEGF-C transgenic mice
-
Jeltsch MM, Kaipainen A, Joukov V, Meng X, Lakso M, Rauvala H, Swartz M, Fukumura D, Jain RK, and Alitalo K (1997). Hyperplasia of lymphatic vessels in VEGF-C transgenic mice. Science 276, 1423-1425.
-
(1997)
Science
, vol.276
, pp. 1423-1425
-
-
Jeltsch, M.M.1
Kaipainen, A.2
Joukov, V.3
Meng, X.4
Lakso, M.5
Rauvala, H.6
Swartz, M.7
Fukumura, D.8
Jain, R.K.9
Alitalo, K.10
-
22
-
-
0031213636
-
VEGF and VEGF-C: Specific induction of angiogenesis and lymphangiogenesis in the differentiated avian chorioallantoic membrane
-
Oh SJ, Jeltsch MM, Birkenhager R, McCarthy JE, Weich HA, Christ B, Alitalo K, and Wilting J (1997). VEGF and VEGF-C: specific induction of angiogenesis and lymphangiogenesis in the differentiated avian chorioallantoic membrane. Dev Biol 188, 96-109.
-
(1997)
Dev Biol
, vol.188
, pp. 96-109
-
-
Oh, S.J.1
Jeltsch, M.M.2
Birkenhager, R.3
McCarthy, J.E.4
Weich, H.A.5
Christ, B.6
Alitalo, K.7
Wilting, J.8
-
23
-
-
0034913270
-
Radio-biological hypoxia, oxygen tension, interstitial fluid pressure and relative viable tumour area in two human squamous cell carcinomas in nude mice during fractionated radiotherapy
-
Baumann M, Appold S, Zimmer J, Scharf M, Beuthien-Baumann B, Dubben HH, Enghardt W, Schreiber A, Eicheler W, and Petersen C (2001). Radio-biological hypoxia, oxygen tension, interstitial fluid pressure and relative viable tumour area in two human squamous cell carcinomas in nude mice during fractionated radiotherapy. Acta Oncol 40(4), 519-528.
-
(2001)
Acta Oncol
, vol.40
, Issue.4
, pp. 519-528
-
-
Baumann, M.1
Appold, S.2
Zimmer, J.3
Scharf, M.4
Beuthien-Baumann, B.5
Dubben, H.H.6
Enghardt, W.7
Schreiber, A.8
Eicheler, W.9
Petersen, C.10
-
24
-
-
84867233885
-
Tumor growth inhibitory effect of ADAMTS1 is accompanied by the inhibition of tumor angiogenesis
-
Obika M, Ogawa H, Takahashi K, Li J, Hatipoglu OF, Cilek MZ, Miyoshi T, Inagaki J, Ohtsuki T, Kusachi S, et al. (2012). Tumor growth inhibitory effect of ADAMTS1 is accompanied by the inhibition of tumor angiogenesis. Cancer Sci 103, 1889-1897.
-
(2012)
Cancer Sci
, vol.103
, pp. 1889-1897
-
-
Obika, M.1
Ogawa, H.2
Takahashi, K.3
Li, J.4
Hatipoglu, O.F.5
Cilek, M.Z.6
Miyoshi, T.7
Inagaki, J.8
Ohtsuki, T.9
Kusachi, S.10
-
25
-
-
0017373031
-
Interstitial fluid pressure in rats measured with a modified wick technique
-
Fadnes HO, Reed RK, and Aukland K (1997). Interstitial fluid pressure in rats measured with a modified wick technique. Microvasc Res 14, 27-36.
-
(1997)
Microvasc Res
, vol.14
, pp. 27-36
-
-
Fadnes, H.O.1
Reed, R.K.2
Aukland, K.3
-
26
-
-
84881061359
-
Ultrasonic quantification of tumor interstitial fluid pressure through scanning acoustic microscopy
-
A Nowicki, J Litniewski, and T Kujawska (Eds). Springer, Berlin, Germany
-
Pflanzer R, Shelke A, Bereiter-Hahn J, and Hofmann M (2012). Ultrasonic quantification of tumor interstitial fluid pressure through scanning acoustic microscopy. In Acoustical Imaging. Vol 31. A Nowicki, J Litniewski, and T Kujawska (Eds). Springer, Berlin, Germany. pp. 291-299.
-
(2012)
Acoustical Imaging
, vol.31
, pp. 291-299
-
-
Pflanzer, R.1
Shelke, A.2
Bereiter-Hahn, J.3
Hofmann, M.4
-
27
-
-
77950458025
-
Expression of LYVE-1 in sinusoidal endothelium is reduced in chronically inflamed human livers
-
Arimoto J, Ikura Y, Suekane T, Nakagawa M, Kitabayashi C, Iwasa Y, Sugioka K, Naruko T, Arakawa T, and Ueda M (2010). Expression of LYVE-1 in sinusoidal endothelium is reduced in chronically inflamed human livers. J Gastroenterol 45, 317-325.
-
(2010)
J Gastroenterol
, vol.45
, pp. 317-325
-
-
Arimoto, J.1
Ikura, Y.2
Suekane, T.3
Nakagawa, M.4
Kitabayashi, C.5
Iwasa, Y.6
Sugioka, K.7
Naruko, T.8
Arakawa, T.9
Ueda, M.10
-
28
-
-
0016277217
-
Diffusion and convection in normal and neoplastic tissues
-
Swabb EA, Wei J, and Gullino PM (1974). Diffusion and convection in normal and neoplastic tissues. Cancer Res 34, 2814-2822.
-
(1974)
Cancer Res
, vol.34
, pp. 2814-2822
-
-
Swabb, E.A.1
Wei, J.2
Gullino, P.M.3
-
29
-
-
0026786660
-
Microvascular pressure is the principal driving force for interstitial hypertension in solid tumors: Implications for vascular collapse
-
Boucher Y and Jain RK (1992). Microvascular pressure is the principal driving force for interstitial hypertension in solid tumors: implications for vascular collapse. Cancer Res 52, 5110-5114.
-
(1992)
Cancer Res
, vol.52
, pp. 5110-5114
-
-
Boucher, Y.1
Jain, R.K.2
-
30
-
-
0028221486
-
Changes in tumour blood flow, oxygenation and interstitial fluid pressure induced by pentoxifylline
-
Lee I, Boucher Y, Demhartner TJ, and Jain RK (1994). Changes in tumour blood flow, oxygenation and interstitial fluid pressure induced by pentoxifylline. Br J Cancer 69(3), 492-496.
-
(1994)
Br J Cancer
, vol.69
, Issue.3
, pp. 492-496
-
-
Lee, I.1
Boucher, Y.2
Demhartner, T.J.3
Jain, R.K.4
-
31
-
-
0026650318
-
Interstitial hypertension in head and neck tumors in patients: Correlation with tumor size
-
Gutmann R, Leunig F, Feyh J, Goetz AE, Messmer K, Kastenbauer E, and Jain RK (1992). Interstitial hypertension in head and neck tumors in patients: correlation with tumor size. Cancer Res 52, 1993-1995.
-
(1992)
Cancer Res
, vol.52
, pp. 1993-1995
-
-
Gutmann, R.1
Leunig, F.2
Feyh, J.3
Goetz, A.E.4
Messmer, K.5
Kastenbauer, E.6
Jain, R.K.7
-
32
-
-
0028475568
-
Interstitial fluid pressure in breast cancer, benign breast conditions, and breast parenchyma
-
Nathanson SD and Nelson L (1994). Interstitial fluid pressure in breast cancer, benign breast conditions, and breast parenchyma. Ann Surg Oncol 1, 333-338.
-
(1994)
Ann Surg Oncol
, vol.1
, pp. 333-338
-
-
Nathanson, S.D.1
Nelson, L.2
-
33
-
-
0033870271
-
Oncotic pressure in solid tumors is elevated
-
Stohrer M, Boucher Y, Stangassinger M, and Jain RK (2000). Oncotic pressure in solid tumors is elevated. Cancer Res 60, 4251-4255.
-
(2000)
Cancer Res
, vol.60
, pp. 4251-4255
-
-
Stohrer, M.1
Boucher, Y.2
Stangassinger, M.3
Jain, R.K.4
-
34
-
-
55449116226
-
Tumor interstitial fluid pressure may regulate angiogenic factors in osteosarcoma
-
Nathan SS, Huvos AG, Casas-Ganem JE, Yang R, Linkov I, Sowers R, DiResta GR, Gorlick R, and Healey JH (2008). Tumor interstitial fluid pressure may regulate angiogenic factors in osteosarcoma. J Orthop Res 26, 1520-1525.
-
(2008)
J Orthop Res
, vol.26
, pp. 1520-1525
-
-
Nathan, S.S.1
Huvos, A.G.2
Casas-Ganem, J.E.3
Yang, R.4
Linkov, I.5
Sowers, R.6
Diresta, G.R.7
Gorlick, R.8
Healey, J.H.9
-
35
-
-
11144355004
-
VEGF-A stimulates lymphangiogenesis and hemangiogenesis in inflammatory neovascularization via macrophage recruitment
-
Cursiefen C, Chen L, Borges LP, Jackson D, Cao J, Radziejewski C, D'Amore PA, Reza Dana M, Wiegand SJ, and Streilein JW (2004). VEGF-A stimulates lymphangiogenesis and hemangiogenesis in inflammatory neovascularization via macrophage recruitment. J Clin Invest 113, 1040-1050.
-
(2004)
J Clin Invest
, vol.113
, pp. 1040-1050
-
-
Cursiefen, C.1
Chen, L.2
Borges, L.P.3
Jackson, D.4
Cao, J.5
Radziejewski, C.6
D'Amore, P.A.7
Reza, D.M.8
Wiegand, S.J.9
Streilein, J.W.10
-
36
-
-
36148936760
-
VEGF-A produced by chronically inflamed tissue induces lymphangiogenesis in draining lymph nodes
-
Halin C, Tobler NE, Vigl B, Brown LF, and Detmar M (2007). VEGF-A produced by chronically inflamed tissue induces lymphangiogenesis in draining lymph nodes. Blood 110, 3158-3167.
-
(2007)
Blood
, vol.110
, pp. 3158-3167
-
-
Halin, C.1
Tobler, N.E.2
Vigl, B.3
Brown, L.F.4
Detmar, M.5
-
37
-
-
17144402207
-
VEGF-A induces tumor and sentinel lymph node lymphangiogenesis and promotes lymphatic metastasis
-
Hirakawa S, Kodama S, Kunstfeld R, Kajiya K, Brown LF, and Detmar M (2005). VEGF-A induces tumor and sentinel lymph node lymphangiogenesis and promotes lymphatic metastasis. J Exp Med 201, 1089-1099.
-
(2005)
J Exp Med
, vol.201
, pp. 1089-1099
-
-
Hirakawa, S.1
Kodama, S.2
Kunstfeld, R.3
Kajiya, K.4
Brown, L.F.5
Detmar, M.6
-
38
-
-
0035126049
-
VEGF-D promotes the metastatic spread of tumor cells via the lymphatics
-
Stacker SA, Caesar C, Baldwin ME, Thornton GE, William RA, Prevo R, Jackson DG, Nishikawa SI, Kubo H, and Achen MG (2001). VEGF-D promotes the metastatic spread of tumor cells via the lymphatics. Nat Med 7, 186-191.
-
(2001)
Nat Med
, vol.7
, pp. 186-191
-
-
Stacker, S.A.1
Caesar, C.2
Baldwin, M.E.3
Thornton, G.E.4
William, R.A.5
Prevo, R.6
Jackson, D.G.7
Nishikawa, S.I.8
Kubo, H.9
Achen, M.G.10
-
39
-
-
84894404797
-
Therapeutic lymphangiogenesis with implantation of adipose-derived regenerative cells
-
Shimizu Y, Shibata R, Shintani S, Ishii M, and Murohara T (2012). Therapeutic lymphangiogenesis with implantation of adipose-derived regenerative cells. J Am Heart Assoc 1, e000877.
-
(2012)
J Am Heart Assoc
, vol.1
-
-
Shimizu, Y.1
Shibata, R.2
Shintani, S.3
Ishii, M.4
Murohara, T.5
-
40
-
-
17744390184
-
Vascular endothelial growth factor-C-mediated lymphangiogenesis promotes tumour metastasis
-
Mandiota SJ, Jussila L, Jeltsch M, Compagni A, Baetens D, Prevo R, Banerji S, Huarte J, Montesano R, Jackson DG, et al. (2001). Vascular endothelial growth factor-C-mediated lymphangiogenesis promotes tumour metastasis. EMBO J 20, 671-682.
-
(2001)
EMBO J
, vol.20
, pp. 671-682
-
-
Mandiota, S.J.1
Jussila, L.2
Jeltsch, M.3
Compagni, A.4
Baetens, D.5
Prevo, R.6
Banerji, S.7
Huarte, J.8
Montesano, R.9
Jackson, D.G.10
|