Oxidative stress disrupts purinergic neuromuscular transmission in the inflamed colon

Journal of Physiology

Volumn 591, Issue 15, 2013, Pages 3725-3737

  Roberts, Jane A ^a   Durnin, Leonie ^b   Sharkey, Keith A ^c   Mutafova Yambolieva, Violeta N ^b   Mawe, Gary M ^a  

^a UNIVERSITY OF VERMONT   (United States)

^b UNIVERSITY OF NEVADA SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF CALGARY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

DEXTRAN SULFATE; DICYCLOHEXYLCARBODIIMIDE; HYDROGEN PEROXIDE; OLIGOMYCIN; PURINE; SCAVENGER; TEMPOL; TRINITROBENZENESULFONIC ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN MITOCHONDRION; COLITIS; COLON MOTILITY; DESCENDING COLON; FEMALE; GUINEA PIG; IN VITRO STUDY; INTESTINE MUSCLE; MALE; MOUSE; MUSCLE FIBER MEMBRANE POTENTIAL; NEUROMUSCULAR TRANSMISSION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN SECRETION;

EID: 84881030107     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2013.254136     Document Type: Article

References (28)

1. Brookes SJ (2001). Classes of enteric nerve cells in the guinea-pig small intestine. Anat Rec 262, 58-70.
2. Demel SL, Dong H, Swain GM, Wang X, Kreulen DL & Galligan JJ (2010). Antioxidant treatment restores prejunctional regulation of purinergic transmission in mesenteric arteries of deoxycorticosterone acetate-salt hypertensive rats. Neuroscience 168, 335-345.
3. Durnin L, Hwang SJ, Ward SM, Sanders KM & Mutafova- Yambolieva VN (2012). Adenosine 5-diphosphate-ribose is a neural regulator in primate and murine large intestine along with β-NAD(+). J Physiol 590, 1921-1941.
4. Durnin L, Sanders KM & Mutafova-Yambolieva VN (2013). Differential release of β-NAD(+) and ATP upon activation of enteric motor neurons in primate and murine colons. Neurogastroenterol Motil 25, e194-204.
5. Furness JB (2006). The Enteric Nervous System Blackwell Publishing, Inc., Malden, MA
6. 1 knocked out mice. J Physiol 590, 1943-1956.
7. 1 receptors mediate inhibitory purinergic neuromuscular transmission in the human colon. Am J Physiol Gastrointest Liver Physiol 291, G584-594.
8. Gomez-Pinilla PJ, Camello PJ, Tresguerres JA & Pozo MJ (2010). Tempol protects the gallbladder against ischemia/reperfusion. J Physiol Biochem 66, 161-172.
9. Hoffman JM, Brooks EM & Mawe GM (2010). Gastrointestinal Motility Monitor (GIMM). J Vis Exp http://www.jove.com/index/Details.stp?ID=2435.
10. Hoffman JM, McKnight ND, Sharkey KA & Mawe GM (2011). The relationship between inflammation-induced neuronal excitability and disrupted motor activity in the guinea pig distal colon. Neurogastroenterol Motil 23, 673-e279.
11. 1 purinoreceptors are fundamental to inhibitory motor control of murine colonic excitability and transit. J Physiol 590, 1957-1972.
12. Hwang SJ, Durnin L, Dwyer L, Rhee PL, Ward SM, Koh SD, Sanders KM & Mutafova-Yambolieva VN (2011). β-Nicotinamide adenine dinucleotide is an enteric inhibitory neurotransmitter in human and nonhuman primate colons. Gastroenterology 140, 608-617.
13. Keating DJ (2008). Mitochondrial dysfunction, oxidative stress, regulation of exocytosis and their relevance to neurodegenerative diseases. J Neurochem 104, 298-305.
14. 11 purinoceptors in parasympathetic inhibition of colonic smooth muscle. J Pharmacol Exp Ther 324, 1055-1063.
15. Krauter EM, Linden DR, Sharkey KA & Mawe GM (2007a). Synaptic plasticity in myenteric neurons of the guinea-pig distal colon: presynaptic mechanisms of inflammation- induced synaptic facilitation. J Physiol 581, 787-800.
16. Krauter EM, Strong DS, Brooks EM, Linden DR, Sharkey KA & Mawe GM (2007b). Changes in colonic motility and the electrophysiological properties of myenteric neurons persist following recovery from trinitrobenzene sulfonic acid colitis in the guinea pig. Neurogastroenterol Motil 19, 990-1000.
17. Linden DR, Chen JX, Gershon MD, Sharkey KA & Mawe GM (2003a). Serotonin availability is increased in mucosa of guinea pigs with TNBS-induced colitis. Am J Physiol Gastrointest Liver Physiol 285, G207-216.
18. Linden DR, Foley KF, McQuoid C, Simpson J, Sharkey KA & Mawe GM (2005). Serotonin transporter function and expression are reduced in mice with TNBS-induced colitis. Neurogastroenterol Motil 17, 565-574.
19. Linden DR, Sharkey KA & Mawe GM (2003b). Enhanced excitability of myenteric AH neurones in the inflamed guinea-pig distal colon. J Physiol 547, 589-601.
20. Lomax AE, Mawe GM & Sharkey KA (2005). Synaptic facilitation and enhanced neuronal excitability in the submucosal plexus during experimental colitis in guinea-pig. J Physiol 564, 863-875.
21. Mutafova-Yambolieva VN, Hwang SJ, Hao X, Chen H, Zhu MX, Wood JD, Ward SM & Sanders KM (2007). β-Nicotinamide adenine dinucleotide is an inhibitory neurotransmitter in visceral smooth muscle. Proc Natl Acad Sci U S A 104, 16359-16364.
22. Navarro A & Boveris A (2007). The mitochondrial energy transduction system and the aging process. Am J Physiol Cell Physiol 292, C670-686.
23. Neshat S, deVries M, Barajas-Espinosa AR, Skeith L, Chisholm SP & Lomax AE (2009). Loss of purinergic vascular regulation in the colon during colitis is associated with upregulation of CD39. Am J Physiol Gastrointest Liver Physiol 296, G399-405.
24. Reddy SN, Bazzocchi G, Chan S, Akashi K, Villanueva-Meyer J, Yanni G, Mena I & Snape WJ, Jr (1991). Colonic motility and transit in health and ulcerative colitis. Gastroenterology 101, 1289-1297.
25. Shi XZ, Winston JH & Sarna SK (2011). Differential immune and genetic responses in rat models of Crohn's colitis and ulcerative colitis. Am J Physiol Gastrointest Liver Physiol 300, G41-51.
26. Strong DS, Cornbrooks CF, Roberts JA, Hoffman JM, Sharkey KA & Mawe GM (2010). Purinergic neuromuscular transmission is selectively attenuated in ulcerated regions of inflamed guinea pig distal colon. J Physiol 588, 847-859.
27. Terry PD, Villinger F, Bubenik GA & Sitaraman SV (2009). Melatonin and ulcerative colitis: evidence, biological mechanisms, and future research. Inflamm Bowel Dis 15, 134-140.
28. 1 purinergic receptor in guinea pig small intestine. Am J Physiol Gastrointest Liver Physiol 292, G1483-1489.