RIG-I activation inhibits HIV replication in macrophages

Journal of Leukocyte Biology

Volumn 94, Issue 2, 2013, Pages 337-341

  Wang, Yizhong ^a   Wang, Xu ^a   Li, Jieliang ^a   Zhou, Yu ^a   Ho, Wenzhe ^a  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

APOBEC3; Interferon regulatory factors; Interferon stimulated genes; Type I interferon

Indexed keywords

ALPHA INTERFERON; BETA CHEMOKINE; BETA INTERFERON; LIGAND; RETINOIC ACID INDUCIBLE PROTEIN I;

ARTICLE; CELL STIMULATION; CONTROLLED STUDY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS; INNATE IMMUNITY; MACROPHAGE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; SIGNAL TRANSDUCTION; VIRUS INHIBITION; VIRUS REPLICATION;

APOBEC3; INTERFERON REGULATORY FACTORS; INTERFERON-STIMULATED GENES; TYPE I INTERFERON;

ANTIGENS, CD; CELLS, CULTURED; CHEMOKINES; CYTOSINE DEAMINASE; DEAD-BOX RNA HELICASES; GENE EXPRESSION REGULATION; GPI-LINKED PROTEINS; HIV REVERSE TRANSCRIPTASE; HIV-1; HUMANS; IMMUNITY, INNATE; INTERFERON-ALPHA; INTERFERON-BETA; LIGANDS; MACROPHAGES; MONOCYTES; RECEPTORS, CCR5; RNA, DOUBLE-STRANDED; RNA, VIRAL; SIGNAL TRANSDUCTION; VIRUS REPLICATION;

EID: 84881013177     PISSN: 07415400     EISSN: 19383673     Source Type: Journal    
DOI: 10.1189/jlb.0313158     Document Type: Article

References (40)

1. Carter, C. A., Ehrlich, L. S. (2008) Cell biology of HIV-1 infection of macrophages. Annu. Rev. Microbiol. 62, 425-443.
2. Perno, C. F., Svicher, V., Schols, D., Pollicita, M., Balzarini, J., Aquaro, S. (2006) Therapeutic strategies towards HIV-1 infection in macrophages. Antiviral Res. 71, 293-300.
3. Verani, A., Gras, G., Pancino, G. (2005) Macrophages and HIV-1: dangerous liaisons. Mol. Immunol. 42, 195-212.
4. Borrow, P., Shattock, R. J., Vyakarnam, A. (2010) Innate immunity against HIV: a priority target for HIV prevention research. Retrovirology 7, 84.
5. Katze, M. G., He, Y., Gale Jr., M. (2002) Viruses and interferon: a fight for supremacy. Nat. Rev. Immunol. 2, 675-687.
6. Kawai, T., Akira, S. (2008) Toll-like receptor and RIG-I-like receptor signaling. Ann. N. Y. Acad. Sci. 1143, 1-20.
7. Rehwinkel, J., Tan, C. P., Goubau, D., Schulz, O., Pichlmair, A, Bier, K, Robb, N., Vreede, F., Barclay, W., Fodor, E., Reis e Sousa, C. (2010) RIG-I detects viral genomic RNA during negative-strand RNA virus infection. Cell 140, 397-408.
8. Fujita, T., Onoguchi, K, Onomoto, K, Hirai, R, Yoneyama, M. (2007) Triggering antiviral response by RIG-I-related RNA helicases. Biochimie (Paris) 89, 754-760.
9. Solis, M., Nakhaei, P., Jalalirad, M., Lacoste, J., Douville, R, Arguello, M., Zhao, T., Laughrea, M., Wainberg, M. A, Hiscott, J. (2011) RIG-I-mediated antiviral signaling is inhibited in HIV-1 infection by a pro-tease-mediated sequestration of RIG-I. J. Virol. 85, 1224-1236.
10. Berg, R K, Melchjorsen, J., Rintahaka, J., Diget, E., Soby, S., Horan, K. A, Gorelick, R J., Matikainen, S., Larsen, C. S., Ostergaard, L., Palu-dan, S. R, Mogensen, T. H. (2012) Genomic HIV RNA induces innate immune responses through RIG-I-dependent sensing of secondary-structured RNA. PLoS One 7, e29291.
11. Hassan, N. F., Campbell, D. E., Douglas, S. D. (1986) Purification of human monocytes on gelatin-coated surfaces. J. Immunol. Methods 95, 273-276.
12. Willey, R L., Smith, D. H., Lasky, L. A, Theodore, T. S., Earl, P. L., Moss, B., Capon, D. J., Martin, M. A. (1988) In vitro mutagenesis identifies a region within the envelope gene of the human immunodeficiency virus that is critical for infectivity. J. Virol. 62, 139-147.
13. Ho, W. Z., Lioy, J., Song, L., Cutilli, J. R, Polin, R A, Douglas, S. D. (1992) Infection of cord blood monocyte-derived macrophages with human immunodeficiency virus type 1. J. Virol. 66, 573-579.
14. Li, Y, Zhang, T., Douglas, S. D., Lai, J. P., Xiao, W. D., Pleasure, D. E., Ho, W. Z. (2003) Morphine enhances hepatitis C virus (HCV) replicon expression. Am. J. Pathol. 163, 1167-1175.
15. Zhang, T., Lin, R T., Li, Y, Douglas, S. D., Maxcey, C, Ho, C, Lai, J. P., Wang, Y J., Wan, Q., Ho, W. Z. (2005) Hepatitis C virus inhibits intracellular interferon a expression in human hepatic cell lines. Hepa-tology 42, 819-827.
16. Foy, E., Li, K., Sumpter Jr., R., Loo, Y M., Johnson, C. L., Wang, C, Fish, P. M., Yoneyama, M., Fujita, T., Lemon, S. M., Gale Jr., M. (2005) Control of antiviral defenses through hepatitis C virus disruption of reti-noic acid-inducible gene-I signaling. Proc. Natl. Acad. Sci. USA 102, 2986-2991.
17. Benedict, C. A, Ware, C. F. (2005) Riging a virus trap. Nat. Med. 11, 929-930.
18. Saito, T., Owen, D. M., Jiang, F., Marcotrigiano, J., Gale Jr., M. (2008) Innate immunity induced by composition-dependent RIG-I recognition of hepatitis C virus RNA. Nature 454, 523-527.
19. Wang, Y, Ye, L., Wang, X., Li, J., Song, L., Ho, W. (2013) Retinoic acid inducible gene-I (RIG-I) signaling of hepatic stellate cells inhibits hepatitis C virus replication in hepatocytes. Innate Immun. 19, 193-202.
20. Spiropoulou, C. F., Ranjan, P., Pearce, M. B., Sealy, T. K, Albarino, C. G., Gangappa, S., Fujita, T., Rollin, P. E., Nichol, S. T., Ksiazek, T.G.,Sambhara S., (2009) RIG-I activation inhibits ebolavirus replication. Virology 392, 11-15.
21. Ranjan, P., Jayashankar, L., Deyde, V., Zeng, H., Davis, W. G., Pearce, M. B., Bowzard, J. B., Hoelscher, M. A, Jeisy-Scott, V., Wiens, M. E., Gangappa, S., Gubareva, L., Garcia-Sastre, A, Katz, J. M., Tumpey, T. M., Fujita, T., Sambhara, S. (2010) 5PPP-RNA induced RIG-I activation inhibits drug-resistant avian H5N1 as well as 1918 and 2009 pandemic influenza virus replication. Virol. J. 7, 102.
22. Iversen, M. B., Paludan, S. R (2010) Mechanisms of type III interferon expression. J. Interferon Cytokine Res. 30, 573-578.
23. Schoggins, J. W., Rice, C. M. (2011) Interferon-stimulated genes and their antiviral effector functions. Curr. Opin. Virol. 1, 519-525.
24. Lenschow, D. J., Giannakopoulos, N. V., Gunn, L. J., Johnston, C, O'Guin, A. K, Schmidt, R E., Levine, B., Virgin IV, H. W. (2005) Identification of interferon-stimulated gene 15 as an antiviral molecule during Sindbis virus infection in vivo. J. Virol. 79, 13974-13983.
25. Raychoudhuri, A, Shrivastava, S., Steele, R, Kim, H., Ray, R, Ray, R B. (2011) ISG56 and IFITM1 proteins inhibit hepatitis C virus replication. J. Virol. 85, 12881-12889.
26. Pincetic, A, Kuang, Z., Seo, E. J., Leis, J. (2010) The interferon-induced gene ISG15 blocks retrovirus release from cells late in the budding process. J. Virol. 84, 4725-4736.
27. Silverman, R H. (2007) Viral encounters with 2,5-oligoadenylate synthetase and RNase L during the interferon antiviral response. J. Virol. 81, 12720-12729.
28. Nasr, N., Maddocks, S., Turville, S. G., Harman, A. N., Woolger, N., Hel-big, K. J., Wilkinson, J., Bye, C. R., Wright, T. K, Rambukwelle, D., Don-aghy, H., Beard, M. R, Cunningham, A. L. (2012) HIV-1 infection of human macrophages directly induces Viperin which inhibits viral production. Blood 120, 778-788.
29. Holmes, R K, Malim, M. H., Bishop, K. N. (2007) APOBEC-mediated viral restriction: not simply editing? Trends Biochem. Sci. 32, 118-128.
30. Yu, Q., Chen, D., Konig, R, Mariani, R, Unutmaz, D., Landau, N. R. (2004) APOBEC3B and APOBEC3C are potent inhibitors of simian immunodeficiency virus replication.J. Biol. Chem. 279, 53379-53386.
31. Chiu, Y L., Soros, V. B., Kreisberg, J. F., Stopak, K, Yonemoto, W., Greene, W. C. (2005) Cellular APOBEC3G restricts HIV-1 infection in resting CD4+ T cells. Nature435, 108-114.
32. Wang, F. X., Huang, J., Zhang, H., Ma, X. (2008) APOBEC3G upregula-tion by a interferon restricts human immunodeficiency virus type 1 infection in human peripheral plasmacytoid dendritic cells. J. Gen. Virol. 89, 722-730.
33. Dang, Y, Siew, L. M., Wang, X., Han, Y, Lampen, R., Zheng, Y H. (2008) Human cytidine deaminase APOBEC3H restricts HIV-1 replication. J. Biol. Chem. 283, 11606-11614.
34. Mbisa, J. L., Bu, W., Pathak, V. K. (2010) APOBEC3F and APOBEC3G inhibit HIV-1 DNA integration by different mechanisms. J. Virol. 84, 5250-5259.
35. Mangeat, B., Turelli, P., Caron, G., Friedli, M., Perrin, L., Trono, D. (2003) Broad antiretroviral defence by human APOBEC3G through lethal editing of nascent reverse transcripts. Nature 424, 99-103.
36. Mariani, R., Chen, D., Schrofelbauer, B., Navarro, F., Konig, R, Boll-man, B., Munk, C, Nymark-McMahon, H., Landau, N. R (2003) Species-specific exclusion of APOBEC3G from HIV-1 virions by Vif. Cell 114, 21-31.
37. Zhang, H., Yang, B., Pomerantz, R J., Zhang, C, Arunachalam, S. C, Gao, L. (2003) The cytidine deaminase CEM15 induces hypermutation in newly synthesized HIV-1 DNA. Nature 424, 94-98.
38. Proost, P., Schols, D. (2002) [Role of chemokines in the HIV infection process]. Verh. K. Acad. Geneeskd. Belg. 64, 403-420.
39. Gross, E., Amella, C. A, Pompucci, L., Franchin, G., Sherry, B., Schmidtmayerova, H. (2003) Macrophages and lymphocytes differentially modulate the ability of RANTES to inhibit HIV-1 infection. J. Leu-koc. Biol. 74, 781-790.
40. Neil, S. J., Zang, T., Bieniasz, P. D. (2008) Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu. Nature 451, 425-430.