Identification of QTLs involved in the development of amygdala kindling in the rat

Experimental Animals

Volumn 62, Issue 3, 2013, Pages 181-187

  Hashimoto, Ryoko ^a   Voigt, Birger ^a   Ishimaru, Yuji ^b   Hokao, Ryoji ^c   Chiba, Shigeru ^b   Serikawa, Tadao ^a   Sasa, Masashi ^a   Kuramoto, Takashi ^a  

^a KYOTO UNIVERSITY   (Japan)

^b ASAHIKAWA MEDICAL COLLEGE   (Japan)

^c Institute for Animal Reproduction   (Japan)

Author keywords

Amygdala kindling; Quantitative trait loci; Recombinant inbred strains; Temporal lobe epilepsy

Indexed keywords

AFTERDISCHARGE; AGKR1 GENE; AGKR2 GENE; ALLELE; AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN DEVELOPMENT; CHROMOSOMAL LOCALIZATION; CHROMOSOME 2; CONTROLLED STUDY; ELECTRODE IMPLANT; ELECTROENCEPHALOGRAM; EPILEPTIC DISCHARGE; EPILEPTOGENESIS; FOCAL EPILEPSY; GENE; GENETIC IDENTIFICATION; GENETIC MARKER; GENETIC SUSCEPTIBILITY; HOMOZYGOTE; KINDLING; LINKAGE ANALYSIS; MALE; NONHUMAN; PHENOTYPE; QUANTITATIVE TRAIT LOCUS; RAT; SINGLE NUCLEOTIDE POLYMORPHISM; TONIC CLONIC SEIZURE; ANIMAL; DISEASE MODEL; EPILEPSY; FISCHER 344 RAT; GENETICS; HUMAN; INBRED RAT STRAIN; LONG EVANS RAT; PATHOPHYSIOLOGY; SEIZURE;

AMYGDALA; ANIMALS; DISEASE MODELS, ANIMAL; EPILEPSY; EPILEPSY, PARTIAL, SENSORY; HUMANS; KINDLING, NEUROLOGIC; MALE; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; QUANTITATIVE TRAIT LOCI; RATS, INBRED F344; RATS, INBRED STRAINS; RATS, LONG-EVANS; SEIZURES;

EID: 84881003235     PISSN: 13411357     EISSN: None     Source Type: Journal    
DOI: 10.1538/expanim.62.181     Document Type: Article

References (24)

1. Aitman, T.J., Critser, J.K., Cuppen, E., Dominiczak, A., Fernandez-Suarez, X.M., Flint, J., Gauguier, D., Geurts, A.M., Gould, M., Harris, P.C., Holmdahl, R., Hubner, N., Izsvak, Z., Jacob, H.J., Kuramoto, T., Kwitek, A.E., Marrone, A., Mashimo, T., Moreno, C., Mullins, J., Mullins, L., Olsson, T., Pravenec, M., Riley, L., Saar, K., Serikawa, T., Shull, J.D., Szpirer, C., Twigger, S.N., Voigt, B., and Worley, K. 2008. Progress and prospects in rat genetics: a community view. Nat. Genet. 40: 516-522. [Medline] [CrossRef]
2. Bailey, D.W. 1971. Recombinant-inbred strains. An aid to finding identity, linkage, and function of histocompatibility and other genes. Transplantation 11: 325-327. [Medline] [CrossRef]
3. Bidmon, H.J., Gorg, B., Palomero-Gallagher, N., Schliess, F., Gorji, A., Speckmann, E.J., and Zilles, K. 2005. Bilateral, vascular and perivascular glial upregulation of heat shock protein-27 after repeated epileptic seizures. J. Chem. Neuroanat. 30: 1-16. [Medline] [CrossRef]
4. Gilby, K.L., Da Silva, A.G., and McIntyre, D.C. 2005. Differential GABA(A) subunit expression following status epilepticus in seizure-prone and seizure-resistant rats: A putative mechanism for refractory drug response. Epilepsia 46 (Supple 5): 3-9.
5. Goddard, G.V., McIntyre, D.C., and Leech, C.K. 1969. A permanent change in brain function resulting from daily electrical stimulation. Exp. Neurol. 25: 295-330. [Medline] [CrossRef]
6. Kobayashi, E., Lopes-Cendes, I., Guerreiro, C.A., Sousa, S.C., Guerreiro, M.M., and Cendes, F. 2001. Seizure outcome and hippocampal atrophy in familial mesial temporal lobe epilepsy. Neurology 56: 166-172. [Medline] [CrossRef]
7. Lively, S. and Brown, I.R. 2008. Extracellular matrix protein SC1/hevin in the hippocampus following pilocarpineinduced status epilepticus. J. Neurochem. 107: 1335-1346. [Medline] [CrossRef]
8. Loscher, W., Cramer, S., and Ebert, U. 1998. Differences in kindling development in seven outbred and inbred rat strains. Exp. Neurol. 154: 551-559. [Medline] [CrossRef]
9. Lu, L.M., Shisa, H., Tanuma, J., and Hiai, H. 1999. Propylnitrosourea-induced T-lymphomas in LEXF RI strains of rats: genetic analysis. Br. J. Cancer 80: 855-861. [Medline] [CrossRef]
10. Mashimo, T., Voigt, B., Tsurumi, T., Naoi, K., Nakanishi, S., Yamasaki, K., Kuramoto, T., and Serikawa, T. 2006. A set of highly informative rat simple sequence length polymorphism (SSLP) markers and genetically defined rat strains. BMC Genet. 7: 19. [Medline] [CrossRef]
11. Mohapel, P., Zhang, X., Gillespie, G.W., Chlan-Fourney, J., Hannesson, D.K., Corley, S.M., Li, X.M., and Corcoran, M.E. 2001. Kindling of claustrum and insular cortex: comparison to perirhinal cortex in the rat. Eur. J. Neurosci. 13: 1501-1519. [Medline] [CrossRef]
12. Paxinos, G. and Watson, C. 2005. The rat brain in stereotaxic coordinates. 5th ed. Elsevier Academic Press, Amsterdam; Boston.
13. Plomin, R., McClearn, G.E., Goramaslak, G., and Neiderhiser, J.M. 1991. Use of recombinant inbred strains to detect quantitative trait loci associated with behavior. Behav. Genet. 21: 99-116. [Medline] [CrossRef]
14. Racine, R.J. 1972. Modification of seizure activity by electrical stimulation. I. After-discharge threshold. Electroencephalogr. Clin. Neurophysiol. 32: 269-279. [Medline] [CrossRef]
15. Racine, R.J., Steingart, M., and McIntyre, D.C. 1999. Development of kindling-prone and kindling-resistant rats: selective breeding and electrophysiological studies. Epilepsy Res. 35: 183-195. [Medline] [CrossRef]
16. Saar, K., Beck, A., Bihoreau, M.T., Birney, E., Brocklebank, D., Chen, Y., Cuppen, E., Demonchy, S., Dopazo, J., Flicek, P., Foglio, M., Fujiyama, A., Gut, I.G., Gauguier, D., Guigo, R., Guryev, V., Heinig, M., Hummel, O., Jahn, N., Klages, S., Kren, V., Kube, M., Kuhl, H., Kuramoto, T., Kuroki, Y., Lechner, D., Lee, Y.A., Lopez-Bigas, N., Lathrop, G.M., Mashimo, T., Medina, I., Mott, R., Patone, G., Perrier-Cornet, J.A., Platzer, M., Pravenec, M., Reinhardt, R., Sakaki, Y., Schilhabel, M., Schulz, H., Serikawa, T., Shikhagaie, M., Tatsumoto, S., Taudien, S., Toyoda, A., Voigt, B., Zelenika, D., Zimdahl, H., and Hubner, N. 2008. SNP and haplotype mapping for genetic analysis in the rat. Nat. Genet. 40: 560-566. [Medline] [CrossRef]
17. Schulte, U., Thumfart, J.O., Klocker, N., Sailer, C.A., Bildl, W., Biniossek, M., Dehn, D., Deller, T., Eble, S., Abbass, K., Wangler, T., Knaus, H.G., and Fakler, B. 2006. The epilepsylinked Lgi1 protein assembles into presynaptic Kv1 channels and inhibits inactivation by Kvβeta1. Neuron 49: 697-706. [Medline] [CrossRef]
18. Seeburg, D.P. and Sheng, M. 2008. Activity-induced Pololike kinase 2 is required for homeostatic plasticity of hippocampal neurons during epileptiform activity. J. Neurosci. 28: 6583-6591. [Medline] [CrossRef]
19. Serikawa, T., Mashimo, T., Takizawa, A., Okajima, R., Maedomari, N., Kumafuji, K., Tagami, F., Neoda, Y., Otsuki, M., Nakanishi, S., Yamasaki, K., Voigt, B., and Kuramoto, T. 2009. National BioResource Project-Rat and related activities. Exp. Anim. 58: 333-341. [Medline] [CrossRef]
20. Shin, R.S., Anisman, H., Merali, Z., and McIntyre, D.C. 2004. Amygdala amino acid and monoamine levels in genetically Fast and Slow kindling rat strains during massed amygdala kindling: a microdialysis study. Eur. J. Neurosci. 20: 185-194. [Medline] [CrossRef]
21. Shisa, H., Lu, L., Katoh, H., Kawarai, A., Tanuma, J., Matsushima, Y., and Hiai, H. 1997. The LEXF: a new set of rat recombinant inbred strains between LE/Stm and F344. Mamm. Genome 8: 324-327. [Medline] [CrossRef]
22. Tachibana, M., Lu, L., Hiai, H., Tamura, A., Matsushima, Y., and Shisa, H. 2006. Quantitative trait loci determining weight reduction of testes and pituitary by diethylstilbesterol in LEXF and FXLE recombinant inbred strain rats. Exp. Anim. 55: 91-95. [Medline] [CrossRef]
23. Twigger, S.N., Shimoyama, M., Bromberg, S., Kwitek, A.E., and Jacob, H.J. 2007. The Rat Genome Database, update 2007-easing the path from disease to data and back again. Nucleic Acids Res. 35: D658-D662. [Medline] [CrossRef]
24. Voigt, B., Kuramoto, T., Mashimo, T., Tsurumi, T., Sasaki, Y., Hokao, R., and Serikawa, T. 2008. Evaluation of LEXF/ FXLE rat recombinant inbred strains for genetic dissection of complex traits. Physiol. Genomics 32: 335-342. [Medline]