-
1
-
-
78049485263
-
Estimates of worldwide burden of cancer in 2008: Globocan 2008
-
Ferlay J, Shin HR, Bray F, Forman D, Mathers C, Parkin DM. Estimates of worldwide burden of cancer in 2008: Globocan 2008. Int J Cancer 2010;127:2893-2917.
-
(2010)
Int J Cancer
, vol.127
, pp. 2893-2917
-
-
Ferlay, J.1
Shin, H.R.2
Bray, F.3
Forman, D.4
Mathers, C.5
Parkin, D.M.6
-
2
-
-
67650996754
-
Biomarkers for epithelial-mesenchymal transitions
-
Zeisberg M, Neilson EG. Biomarkers for epithelial-mesenchymal transitions. J Clin Invest 2009;119:1429-1437.
-
(2009)
J Clin Invest
, vol.119
, pp. 1429-1437
-
-
Zeisberg, M.1
Neilson, E.G.2
-
3
-
-
75649143275
-
Epithelial-mesenchymal transition in hepatocellular carcinoma
-
Van Zijl F, Zulehner G, Petz M, Schneller D, Kornauth C, Hau M, et al. Epithelial-mesenchymal transition in hepatocellular carcinoma. Future Oncol 2009;5:1169-1179.
-
(2009)
Future Oncol
, vol.5
, pp. 1169-1179
-
-
Van Zijl, F.1
Zulehner, G.2
Petz, M.3
Schneller, D.4
Kornauth, C.5
Hau, M.6
-
4
-
-
44449144396
-
Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis
-
Yang J, Weinberg RA. Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis. Dev Cell 2008;14:818-829.
-
(2008)
Dev Cell
, vol.14
, pp. 818-829
-
-
Yang, J.1
Weinberg, R.A.2
-
5
-
-
78649364332
-
Hypoxia-inducible factors and the response to hypoxic stress
-
Majmundar AJ, Wong WJ, Simon MC. Hypoxia-inducible factors and the response to hypoxic stress. Mol Cell 2010;40:294-309.
-
(2010)
Mol Cell
, vol.40
, pp. 294-309
-
-
Majmundar, A.J.1
Wong, W.J.2
Simon, M.C.3
-
6
-
-
84859445000
-
Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy
-
Semenza GL. Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy. Trends Pharmacol Sci 2012;33:207-214.
-
(2012)
Trends Pharmacol Sci
, vol.33
, pp. 207-214
-
-
Semenza, G.L.1
-
7
-
-
0030816109
-
Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth
-
Maxwell PH, Dachs GU, Gleadle JM, Nicholls LG, Harris AL, Stratford IJ, et al. Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth. Proc Natl Acad Sci U S A 1997;94:8104-8109.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 8104-8109
-
-
Maxwell, P.H.1
Dachs, G.U.2
Gleadle, J.M.3
Nicholls, L.G.4
Harris, A.L.5
Stratford, I.J.6
-
8
-
-
77955010960
-
Hypoxia: a link between fibrogenesis, angiogenesis, and carcinogenesis in liver disease
-
Rosmorduc O, Housset C. Hypoxia: a link between fibrogenesis, angiogenesis, and carcinogenesis in liver disease. Semin Liver Dis 2010;30:258-270.
-
(2010)
Semin Liver Dis
, vol.30
, pp. 258-270
-
-
Rosmorduc, O.1
Housset, C.2
-
9
-
-
18744375998
-
Regulation and destabilization of HIF-1alpha by ARD1-mediated acetylation
-
Jeong JW, Bae MK, Ahn MY, Kim SH, Sohn TK, Bae MH, et al. Regulation and destabilization of HIF-1alpha by ARD1-mediated acetylation. Cell 2002;111:709-720.
-
(2002)
Cell
, vol.111
, pp. 709-720
-
-
Jeong, J.W.1
Bae, M.K.2
Ahn, M.Y.3
Kim, S.H.4
Sohn, T.K.5
Bae, M.H.6
-
10
-
-
33645322383
-
Metastasis-associated protein 1 enhances stability of hypoxia-inducible factor-1alpha protein by recruiting histone deacetylase 1
-
Yoo YG, Kong G, Lee MO. Metastasis-associated protein 1 enhances stability of hypoxia-inducible factor-1alpha protein by recruiting histone deacetylase 1. EMBO J 2006;25:1231-1241.
-
(2006)
EMBO J
, vol.25
, pp. 1231-1241
-
-
Yoo, Y.G.1
Kong, G.2
Lee, M.O.3
-
11
-
-
77950476293
-
ERbeta impedes prostate cancer EMT by destabilizing HIF-1alpha and inhibiting VEGF-mediated Snail nuclear localization: implications for gleason grading
-
Mak P, Leav I, Pursell B, Bae D, Yang X, Taglienti CA, et al. ERbeta impedes prostate cancer EMT by destabilizing HIF-1alpha and inhibiting VEGF-mediated Snail nuclear localization: implications for gleason grading. Cancer Cell 2010;17:319-332.
-
(2010)
Cancer Cell
, vol.17
, pp. 319-332
-
-
Mak, P.1
Leav, I.2
Pursell, B.3
Bae, D.4
Yang, X.5
Taglienti, C.A.6
-
12
-
-
40249113328
-
Direct regulation of twist by HIF-1alpha promotes metastasis
-
Yang MH, Wu MZ, Chiou SH, Chen PM, Chang SY, Liu CJ, et al. Direct regulation of twist by HIF-1alpha promotes metastasis. Nat Cell Biol 2008;10:295-305.
-
(2008)
Nat Cell Biol
, vol.10
, pp. 295-305
-
-
Yang, M.H.1
Wu, M.Z.2
Chiou, S.H.3
Chen, P.M.4
Chang, S.Y.5
Liu, C.J.6
-
14
-
-
0033932899
-
Hepatocyte migration during liver development requires Prox1
-
Sosa-Pineda B, Wigle JT, Oliver G. Hepatocyte migration during liver development requires Prox1. Nat Genet 2000;25:254-255.
-
(2000)
Nat Genet
, vol.25
, pp. 254-255
-
-
Sosa-Pineda, B.1
Wigle, J.T.2
Oliver, G.3
-
15
-
-
75949088814
-
Expression of Prox1 is a common feature of high-grade malignant astrocytic gliomas
-
Elsir T, Eriksson A, Orrego A, Lindstrom MS, Nister M. Expression of Prox1 is a common feature of high-grade malignant astrocytic gliomas. J Neuropathol Exp Neurol 2010;69:129-138.
-
(2010)
J Neuropathol Exp Neurol
, vol.69
, pp. 129-138
-
-
Elsir, T.1
Eriksson, A.2
Orrego, A.3
Lindstrom, M.S.4
Nister, M.5
-
16
-
-
80054998429
-
Expression and prognostic value of transcription factor PROX1 in colorectal cancer
-
Skog M, Bono P, Lundin M, Lundin J, Louhimo J, Linder N, et al. Expression and prognostic value of transcription factor PROX1 in colorectal cancer. Br J Cancer 2011;105:1346-1351.
-
(2011)
Br J Cancer
, vol.105
, pp. 1346-1351
-
-
Skog, M.1
Bono, P.2
Lundin, M.3
Lundin, J.4
Louhimo, J.5
Linder, N.6
-
17
-
-
42949112116
-
Transcription factor Prox1 induces colon cancer progression by promoting the transition from benign to highly dysplastic phenotype
-
Petrova TV, Nykanen A, Norrmen C, Ivanov KI, Andersson LC, Haglund C, et al. Transcription factor Prox1 induces colon cancer progression by promoting the transition from benign to highly dysplastic phenotype. Cancer Cell 2008;13:407-419.
-
(2008)
Cancer Cell
, vol.13
, pp. 407-419
-
-
Petrova, T.V.1
Nykanen, A.2
Norrmen, C.3
Ivanov, K.I.4
Andersson, L.C.5
Haglund, C.6
-
18
-
-
33750733603
-
A homeobox protein, Prox1, is involved in the differentiation, proliferation, and prognosis in hepatocellular carcinoma
-
Shimoda M, Takahashi M, Yoshimoto T, Kono T, Ikai I, Kubo H. A homeobox protein, Prox1, is involved in the differentiation, proliferation, and prognosis in hepatocellular carcinoma. Clin Cancer Res 2006;12:6005-6011.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 6005-6011
-
-
Shimoda, M.1
Takahashi, M.2
Yoshimoto, T.3
Kono, T.4
Ikai, I.5
Kubo, H.6
-
19
-
-
42949106011
-
Altered regulation of Prox1-gene-expression in liver tumors
-
Dudas J, Mansuroglu T, Moriconi F, Haller F, Wilting J, Lorf T, et al. Altered regulation of Prox1-gene-expression in liver tumors. BMC Cancer 2008;8:92.
-
(2008)
BMC Cancer
, vol.8
, pp. 92
-
-
Dudas, J.1
Mansuroglu, T.2
Moriconi, F.3
Haller, F.4
Wilting, J.5
Lorf, T.6
-
20
-
-
45749137283
-
High expression of macrophage colony-stimulating factor in peritumoral liver tissue is associated with poor survival after curative resection of hepatocellular carcinoma
-
Zhu XD, Zhang JB, Zhuang PY, Zhu HG, Zhang W, Xiong YQ, et al. High expression of macrophage colony-stimulating factor in peritumoral liver tissue is associated with poor survival after curative resection of hepatocellular carcinoma. J Clin Oncol 2008;26:2707-2716.
-
(2008)
J Clin Oncol
, vol.26
, pp. 2707-2716
-
-
Zhu, X.D.1
Zhang, J.B.2
Zhuang, P.Y.3
Zhu, H.G.4
Zhang, W.5
Xiong, Y.Q.6
-
21
-
-
0037391756
-
Predicting hepatitis B virus-positive metastatic hepatocellular carcinomas using gene expression profiling and supervised machine learning
-
Ye QH, Qin LX, Forgues M, He P, Kim JW, Peng AC, et al. Predicting hepatitis B virus-positive metastatic hepatocellular carcinomas using gene expression profiling and supervised machine learning. Nat Med 2003;9:416-423.
-
(2003)
Nat Med
, vol.9
, pp. 416-423
-
-
Ye, Q.H.1
Qin, L.X.2
Forgues, M.3
He, P.4
Kim, J.W.5
Peng, A.C.6
-
22
-
-
5044219860
-
Prospero-related homeobox (Prox1) is a corepressor of human liver receptor homolog-1 and suppresses the transcription of the cholesterol 7-alpha-hydroxylase gene
-
Qin J, Gao DM, Jiang QF, Zhou Q, Kong YY, Wang Y, et al. Prospero-related homeobox (Prox1) is a corepressor of human liver receptor homolog-1 and suppresses the transcription of the cholesterol 7-alpha-hydroxylase gene. Mol Endocrinol 2004;18:2424-2439.
-
(2004)
Mol Endocrinol
, vol.18
, pp. 2424-2439
-
-
Qin, J.1
Gao, D.M.2
Jiang, Q.F.3
Zhou, Q.4
Kong, Y.Y.5
Wang, Y.6
-
23
-
-
31844436517
-
Early and late recurrence after liver resection for hepatocellular carcinoma: prognostic and therapeutic implications
-
Portolani N, Coniglio A, Ghidoni S, Giovanelli M, Benetti A, Tiberio GA, et al. Early and late recurrence after liver resection for hepatocellular carcinoma: prognostic and therapeutic implications. Ann Surg 2006;243:229-235.
-
(2006)
Ann Surg
, vol.243
, pp. 229-235
-
-
Portolani, N.1
Coniglio, A.2
Ghidoni, S.3
Giovanelli, M.4
Benetti, A.5
Tiberio, G.A.6
-
24
-
-
78751544628
-
P28gank overexpression accelerates hepatocellular carcinoma invasiveness and metastasis via phosphoinositol 3-kinase/akt/hypoxia-inducible factor-1alpha pathways
-
Fu J, Chen Y, Cao J, Luo T, Qian YW, Yang W, et al. P28gank overexpression accelerates hepatocellular carcinoma invasiveness and metastasis via phosphoinositol 3-kinase/akt/hypoxia-inducible factor-1alpha pathways. Hepatology 2011;53:181-192.
-
(2011)
Hepatology
, vol.53
, pp. 181-192
-
-
Fu, J.1
Chen, Y.2
Cao, J.3
Luo, T.4
Qian, Y.W.5
Yang, W.6
-
25
-
-
77954749688
-
Clinical significance of lymph node metastasis in patients undergoing partial hepatectomy for hepatocellular carcinoma
-
Xiaohong S, Huikai L, Feng W, Ti Z, Yunlong C, Qiang L. Clinical significance of lymph node metastasis in patients undergoing partial hepatectomy for hepatocellular carcinoma. World J Surg 2010;34:1028-1033.
-
(2010)
World J Surg
, vol.34
, pp. 1028-1033
-
-
Xiaohong, S.1
Huikai, L.2
Feng, W.3
Ti, Z.4
Yunlong, C.5
Qiang, L.6
-
26
-
-
77951176116
-
CHD1L promotes hepatocellular carcinoma progression and metastasis in mice and is associated with these processes in human patients
-
Chen L, Chan TH, Yuan YF, Hu L, Huang J, Ma S, et al. CHD1L promotes hepatocellular carcinoma progression and metastasis in mice and is associated with these processes in human patients. J Clin Invest 2010;120:1178-1191.
-
(2010)
J Clin Invest
, vol.120
, pp. 1178-1191
-
-
Chen, L.1
Chan, T.H.2
Yuan, Y.F.3
Hu, L.4
Huang, J.5
Ma, S.6
-
27
-
-
4644271628
-
Overexpression of cortactin is involved in motility and metastasis of hepatocellular carcinoma
-
Chuma M, Sakamoto M, Yasuda J, Fujii G, Nakanishi K, Tsuchiya A, et al. Overexpression of cortactin is involved in motility and metastasis of hepatocellular carcinoma. J Hepatol 2004;41:629-636.
-
(2004)
J Hepatol
, vol.41
, pp. 629-636
-
-
Chuma, M.1
Sakamoto, M.2
Yasuda, J.3
Fujii, G.4
Nakanishi, K.5
Tsuchiya, A.6
-
28
-
-
33644518424
-
Clusterin plays an important role in hepatocellular carcinoma metastasis
-
Lau SH, Sham JS, Xie D, Tzang CH, Tang D, Ma N, et al. Clusterin plays an important role in hepatocellular carcinoma metastasis. Oncogene 2006;25:1242-1250.
-
(2006)
Oncogene
, vol.25
, pp. 1242-1250
-
-
Lau, S.H.1
Sham, J.S.2
Xie, D.3
Tzang, C.H.4
Tang, D.5
Ma, N.6
-
29
-
-
33749344520
-
Twist overexpression correlates with hepatocellular carcinoma metastasis through induction of epithelial-mesenchymal transition
-
Lee TK, Poon RT, Yuen AP, Ling MT, Kwok WK, Wang XH, et al. Twist overexpression correlates with hepatocellular carcinoma metastasis through induction of epithelial-mesenchymal transition. Clin Cancer Res 2006;12:5369-5376.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 5369-5376
-
-
Lee, T.K.1
Poon, R.T.2
Yuen, A.P.3
Ling, M.T.4
Kwok, W.K.5
Wang, X.H.6
-
30
-
-
34347359742
-
The significance of proline-rich tyrosine kinase2 (pyk2) on hepatocellular carcinoma progression and recurrence
-
Sun CK, Ng KT, Sun BS, Ho JW, Lee TK, Ng I, et al. The significance of proline-rich tyrosine kinase2 (pyk2) on hepatocellular carcinoma progression and recurrence. Br J Cancer 2007;97:50-57.
-
(2007)
Br J Cancer
, vol.97
, pp. 50-57
-
-
Sun, C.K.1
Ng, K.T.2
Sun, B.S.3
Ho, J.W.4
Lee, T.K.5
Ng, I.6
-
31
-
-
33645029278
-
HTPAP gene on chromosome 8p is a candidate metastasis suppressor for human hepatocellular carcinoma
-
Wu X, Jia HL, Wang YF, Ren N, Ye QH, Sun HC, et al. HTPAP gene on chromosome 8p is a candidate metastasis suppressor for human hepatocellular carcinoma. Oncogene 2006;25:1832-1840.
-
(2006)
Oncogene
, vol.25
, pp. 1832-1840
-
-
Wu, X.1
Jia, H.L.2
Wang, Y.F.3
Ren, N.4
Ye, Q.H.5
Sun, H.C.6
-
32
-
-
72949120827
-
Comprehensive analysis of the independent effect of Twist and Snail in promoting metastasis of hepatocellular carcinoma
-
Yang MH, Chen CL, Chau GY, Chiou SH, Su CW, Chou TY, et al. Comprehensive analysis of the independent effect of Twist and Snail in promoting metastasis of hepatocellular carcinoma. Hepatology 2009;50:1464-1474.
-
(2009)
Hepatology
, vol.50
, pp. 1464-1474
-
-
Yang, M.H.1
Chen, C.L.2
Chau, G.Y.3
Chiou, S.H.4
Su, C.W.5
Chou, T.Y.6
-
33
-
-
33744504720
-
A prospero-related homeodomain protein is a novel co-regulator of hepatocyte nuclear factor 4alpha that regulates the cholesterol 7alpha-hydroxylase gene
-
Song KH, Li T, Chiang JY. A prospero-related homeodomain protein is a novel co-regulator of hepatocyte nuclear factor 4alpha that regulates the cholesterol 7alpha-hydroxylase gene. J Biol Chem 2006;281:10081-10088.
-
(2006)
J Biol Chem
, vol.281
, pp. 10081-10088
-
-
Song, K.H.1
Li, T.2
Chiang, J.Y.3
-
34
-
-
44849100198
-
NF-kappaB links innate immunity to the hypoxic response through transcriptional regulation of hif-1alpha
-
Rius J, Guma M, Schachtrup C, Akassoglou K, Zinkernagel AS, Nizet V, et al. NF-kappaB links innate immunity to the hypoxic response through transcriptional regulation of hif-1alpha. Nature 2008;453:807-811.
-
(2008)
Nature
, vol.453
, pp. 807-811
-
-
Rius, J.1
Guma, M.2
Schachtrup, C.3
Akassoglou, K.4
Zinkernagel, A.S.5
Nizet, V.6
|