메뉴 건너뛰기




Volumn , Issue JUL, 2013, Pages

Increased Body Weight of the BAC HD Transgenic Mouse Model of Huntington's Disease Accounts for Some but Not All of the Observed HD-like Motor Deficits

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ARTICLE; BACTERIAL ARTIFICIAL CHROMOSOME; BEHAVIOR; BODY WEIGHT; COMPARATIVE STUDY; CONTROLLED STUDY; DIET RESTRICTION; EXPERIMENTAL MODEL; FEMALE; GENOTYPE; HUNTINGTON CHOREA; LOCOMOTION; MOUSE; NONHUMAN; OPEN FIELD TEST; REARING; ROTAROD TEST; TRANSGENIC ANIMAL;

EID: 84880952695     PISSN: None     EISSN: 21573999     Source Type: Journal    
DOI: 10.1371/currents.hd.0ab4f3645aff523c56ecc8ccbe41a198     Document Type: Article
Times cited : (25)

References (27)
  • 2
    • 0027480960 scopus 로고
    • The Huntington9s Disease Collaborative Research Group
    • A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington9s disease chromosomes, Mar 26, PubMed PMID:8458085. 8458085
    • A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington9s disease chromosomes. The Huntington9s Disease Collaborative Research Group. Cell. 1993 Mar 26;72(6):971-83. PubMed PMID:8458085. 8458085.
    • (1993) Cell. , vol.72 , Issue.6 , pp. 971-983
  • 3
    • 51349162486 scopus 로고    scopus 로고
    • Rodent genetic models of Huntington disease
    • Oct, PubMed PMID:18638556. 18638556
    • Heng MY, Detloff PJ, Albin RL. Rodent genetic models of Huntington disease. Neurobiol Dis. 2008 Oct;32(1):1-9. PubMed PMID:18638556. 18638556.
    • (2008) Neurobiol Dis. , vol.32 , Issue.1 , pp. 1-9
    • Heng, M.Y.1    Detloff, P.J.2    Albin, R.L.3
  • 5
    • 46749157501 scopus 로고    scopus 로고
    • Full-length human mutant huntingtin with a stable polyglutamine repeat can elicit progressive and selective neuropathogenesis in BACHD mice
    • Jun 11, PubMed PMID:18550760. 18550760
    • Gray M, Shirasaki DI, Cepeda C, André VM, Wilburn B, Lu XH, Tao J, Yamazaki I, Li SH, Sun YE, Li XJ, Levine MS, Yang XW. Full-length human mutant huntingtin with a stable polyglutamine repeat can elicit progressive and selective neuropathogenesis in BACHD mice. J Neurosci. 2008 Jun 11;28(24):6182-95. PubMed PMID:18550760. 18550760.
    • (2008) J Neurosci. , vol.28 , Issue.24 , pp. 6182-6195
    • Gray, M.1    Shirasaki, D.I.2    Cepeda, C.3    André, V.M.4    Wilburn, B.5    Lu, X.H.6    Tao, J.7    Yamazaki, I.8    Li, S.H.9    Sun, Y.E.10    Li, X.J.11    Levine, M.S.12    Yang, X.W.13
  • 6
    • 0033613212 scopus 로고    scopus 로고
    • Insoluble detergent-resistant aggregates form between pathological and nonpathological lengths of polyglutamine in mammalian cells
    • Sep 28, PubMed PMID:10500189. 10500189
    • Kazantsev A, Preisinger E, Dranovsky A, Goldgaber D, Housman D. Insoluble detergent-resistant aggregates form between pathological and nonpathological lengths of polyglutamine in mammalian cells. Proc Natl Acad Sci U S A. 1999 Sep 28;96(20):11404-9. PubMed PMID:10500189. 10500189.
    • (1999) Proc Natl Acad Sci U S A. , vol.96 , Issue.20 , pp. 11404-11409
    • Kazantsev, A.1    Preisinger, E.2    Dranovsky, A.3    Goldgaber, D.4    Housman, D.5
  • 12
    • 29644433445 scopus 로고    scopus 로고
    • Selective degeneration and nuclear localization of mutant huntingtin in the YAC128 mouse model of Huntington disease
    • Dec 15, PubMed PMID:16278236. 16278236
    • Van Raamsdonk JM, Murphy Z, Slow EJ, Leavitt BR, Hayden MR. Selective degeneration and nuclear localization of mutant huntingtin in the YAC128 mouse model of Huntington disease. Hum Mol Genet. 2005 Dec 15;14(24):3823-35. PubMed PMID:16278236. 16278236.
    • (2005) Hum Mol Genet. , vol.14 , Issue.24 , pp. 3823-3835
    • Van Raamsdonk, J.M.1    Murphy, Z.2    Slow, E.J.3    Leavitt, B.R.4    Hayden, M.R.5
  • 14
  • 15
    • 80055002896 scopus 로고    scopus 로고
    • In vivo Dopamine Efflux is Decreased in Striatum of both Fragment (R6/2) and Full-Length (YAC128) Transgenic Mouse Models of Huntington9s Disease
    • PubMed PMID:21811446. 21811446
    • Callahan JW, Abercrombie ED. In vivo Dopamine Efflux is Decreased in Striatum of both Fragment (R6/2) and Full-Length (YAC128) Transgenic Mouse Models of Huntington9s Disease. Front Syst Neurosci. 2011;5:61. PubMed PMID:21811446. 21811446.
    • (2011) Front Syst Neurosci. , vol.5 , pp. 61
    • Callahan, J.W.1    Abercrombie, E.D.2
  • 16
    • 80055025489 scopus 로고    scopus 로고
    • Selective cognitive impairment in the YAC128 Huntington9s disease mouse
    • Jun 1, PubMed PMID:21624441. 21624441
    • Brooks SP, Janghra N, Higgs GV, Bayram-Weston Z, Heuer A, Jones L, Dunnett SB. Selective cognitive impairment in the YAC128 Huntington9s disease mouse. Brain Res Bull. 2012 Jun 1;88(2-3):121-9. PubMed PMID:21624441. 21624441.
    • (2012) Brain Res Bull. , vol.88 , Issue.2-3 , pp. 121-129
    • Brooks, S.P.1    Janghra, N.2    Higgs, G.V.3    Bayram-Weston, Z.4    Heuer, A.5    Jones, L.6    Dunnett, S.B.7
  • 17
    • 0041466271 scopus 로고    scopus 로고
    • Differences among eight inbred strains of mice in motor ability and motor learning on a rotorod
    • Aug, PubMed PMID:12953787. 12953787
    • McFadyen MP, Kusek G, Bolivar VJ, Flaherty L. Differences among eight inbred strains of mice in motor ability and motor learning on a rotorod. Genes Brain Behav. 2003 Aug;2(4):214-9. PubMed PMID:12953787. 12953787.
    • (2003) Genes Brain Behav. , vol.2 , Issue.4 , pp. 214-219
    • McFadyen, M.P.1    Kusek, G.2    Bolivar, V.J.3    Flaherty, L.4
  • 18
    • 84856287728 scopus 로고    scopus 로고
    • Screening of therapeutic strategies for Huntington9s disease in YAC128 transgenic mice
    • Jan, PubMed PMID:21501423. 21501423
    • Gil-Mohapel JM. Screening of therapeutic strategies for Huntington9s disease in YAC128 transgenic mice. CNS Neurosci Ther. 2012 Jan;18(1):77-86. PubMed PMID:21501423. 21501423.
    • (2012) CNS Neurosci Ther. , vol.18 , Issue.1 , pp. 77-86
    • Gil-Mohapel, J.M.1
  • 20
    • 80053158120 scopus 로고    scopus 로고
    • Expanded polyglutamine-binding peptoid as a novel therapeutic agent for treatment of Huntington9s disease
    • Sep 23, PubMed PMID:21944750. 21944750
    • Chen X, Wu J, Luo Y, Liang X, Supnet C, Kim MW, Lotz GP, Yang G, Muchowski PJ, Kodadek T, Bezprozvanny I. Expanded polyglutamine-binding peptoid as a novel therapeutic agent for treatment of Huntington9s disease. Chem Biol. 2011 Sep 23;18(9):1113-25. PubMed PMID:21944750. 21944750.
    • (2011) Chem Biol. , vol.18 , Issue.9 , pp. 1113-1125
    • Chen, X.1    Wu, J.2    Luo, Y.3    Liang, X.4    Supnet, C.5    Kim, M.W.6    Lotz, G.P.7    Yang, G.8    Muchowski, P.J.9    Kodadek, T.10    Bezprozvanny, I.11
  • 21
    • 77955278434 scopus 로고    scopus 로고
    • Genetically engineered mesenchymal stem cells reduce behavioral deficits in the YAC 128 mouse model of Huntington9s disease
    • Dec 25, PubMed PMID:20493905. 20493905
    • Dey ND, Bombard MC, Roland BP, Davidson S, Lu M, Rossignol J, Sandstrom MI, Skeel RL, Lescaudron L, Dunbar GL. Genetically engineered mesenchymal stem cells reduce behavioral deficits in the YAC 128 mouse model of Huntington9s disease. Behav Brain Res. 2010 Dec 25;214(2):193-200. PubMed PMID:20493905. 20493905.
    • (2010) Behav Brain Res. , vol.214 , Issue.2 , pp. 193-200
    • Dey, N.D.1    Bombard, M.C.2    Roland, B.P.3    Davidson, S.4    Lu, M.5    Rossignol, J.6    Sandstrom, M.I.7    Skeel, R.L.8    Lescaudron, L.9    Dunbar, G.L.10
  • 22
    • 0032251946 scopus 로고    scopus 로고
    • Using SAS PROC MIXED to fit multilevel models, hierarchical models, and individual growth models
    • Singer J. Using SAS PROC MIXED to fit multilevel models, hierarchical models, and individual growth models. Journal of Educational and Behavioral Statistics, Vol. 23, No. 4 (Winter, 1998), pp. 323-355.
    • (1998) Journal of Educational and Behavioral Statistics , vol.23 , Issue.4 Winter , pp. 323-355
    • Singer, J.1
  • 23
    • 84876500657 scopus 로고    scopus 로고
    • Changes in behaviors of male C57BL/6J mice across adult life span and effects of dietary restriction
    • Dec, PubMed PMID:21989972. 21989972
    • Fahlström A, Zeberg H, Ulfhake B. Changes in behaviors of male C57BL/6J mice across adult life span and effects of dietary restriction. Age (Dordr). 2012 Dec;34(6):1435-52. PubMed PMID:21989972. 21989972.
    • (2012) Age (Dordr). , vol.34 , Issue.6 , pp. 1435-1452
    • Fahlström, A.1    Zeberg, H.2    Ulfhake, B.3
  • 24
    • 0023156812 scopus 로고
    • Dietary restriction benefits learning and motor performance of aged mice
    • Jan, PubMed PMID:3794202. 3794202
    • Ingram DK, Weindruch R, Spangler EL, Freeman JR, Walford RL. Dietary restriction benefits learning and motor performance of aged mice. J Gerontol. 1987 Jan;42(1):78-81. PubMed PMID:3794202. 3794202.
    • (1987) J Gerontol. , vol.42 , Issue.1 , pp. 78-81
    • Ingram, D.K.1    Weindruch, R.2    Spangler, E.L.3    Freeman, J.R.4    Walford, R.L.5
  • 25
    • 0024829444 scopus 로고
    • The effects of life-long food restriction on spatial memory in young and aged Fischer 344 rats measured in the eight-arm radial and the Morris water mazes
    • Nov-Dec, PubMed PMID:2628778. 2628778
    • Stewart J, Mitchell J, Kalant N. The effects of life-long food restriction on spatial memory in young and aged Fischer 344 rats measured in the eight-arm radial and the Morris water mazes. Neurobiol Aging. 1989 Nov-Dec;10(6):669-75. PubMed PMID:2628778. 2628778.
    • (1989) Neurobiol Aging. , vol.10 , Issue.6 , pp. 669-675
    • Stewart, J.1    Mitchell, J.2    Kalant, N.3
  • 27
    • 0037418339 scopus 로고    scopus 로고
    • Dietary restriction normalizes glucose metabolism and BDNF levels, slows disease progression, and increases survival in huntingtin mutant mice
    • Mar 4, PubMed PMID:12589027. 12589027
    • Duan W, Guo Z, Jiang H, Ware M, Li XJ, Mattson MP. Dietary restriction normalizes glucose metabolism and BDNF levels, slows disease progression, and increases survival in huntingtin mutant mice. Proc Natl Acad Sci U S A. 2003 Mar 4;100(5):2911-6. PubMed PMID:12589027. 12589027.
    • (2003) Proc Natl Acad Sci U S A. , vol.100 , Issue.5 , pp. 2911-2916
    • Duan, W.1    Guo, Z.2    Jiang, H.3    Ware, M.4    Li, X.J.5    Mattson, M.P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.