Why mammals more susceptible to the hepatotoxic microcystins than fish: Evidences from plasma and albumin protein binding through equilibrium dialysis

Ecotoxicology

Volumn 22, Issue 6, 2013, Pages 1012-1019

  Zhang, Wei ^a,b   Liang, Gaodao ^a   Wu, Laiyan ^a   Tuo, Xun ^a   Wang, Wenjing ^a   Chen, Jun ^a   Xie, Ping ^a  

^a INSTITUTE OF HYDROBIOLOGY   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

Albumin; Equilibrium dialysis; Microcystins; Plasma protein

Indexed keywords

ALBUMIN; MICROCYSTIN LR; MICROCYSTIN RR;

BIOLOGICAL ANALYSIS; FISH; MAMMAL; PEPTIDE; PLASMA; PROTEIN;

ARTICLE; BINDING AFFINITY; CARP; CONTROLLED STUDY; COW; DISEASE PREDISPOSITION; EQUILIBRIUM DIALYSIS; FISH; HALF LIFE TIME; HUMAN; HUMAN VERSUS ANIMAL COMPARISON; LIVER TOXICITY; MAMMAL; NONHUMAN; PLASMA PROTEIN BINDING; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN CONTENT; SPECIES DIFFERENCE; SWINE; TOXICITY TESTING;

ALBUMINS; ANIMALS; BLOOD PROTEINS; FISHES; HALF-LIFE; HUMANS; LIVER; MAMMALS; MICROCYSTINS; PROTEIN BINDING;

MAMMALIA;

EID: 84880921624     PISSN: 09639292     EISSN: 15733017     Source Type: Journal    
DOI: 10.1007/s10646-013-1086-5     Document Type: Article

References (49)

1. Ascoli G, Domenici E, Bertucci C (2006) Drug binding to human serum albumin: abridged review of results obtained with high-performance liquid chromatography and circular dichroism. Chirality 18(9):667-679
2. Baranczewski P, Stañczak A, Sundberg K, Svensson R, Wallin A, Jansson J, Garberg P, Postlind H (2006) Introduction to in vitro estimation of metabolic stability and drug interactions of new chemical entities in drug discovery and development. Pharmacol Rep 58(4):453-472
3. Botes D, Tuinman A, Wessels P, Viljoen C, Kruger H, Williams D, Santikarn S, Smith R, Hammond S (1984) The structure of cyanoginosin-LA, a cyclic heptapeptide toxin from the cyanobacterium Microcystis aeruginosa. J Chem Soc Perkin Trans 1(1984):2311-2318
4. Brooks WP, Codd GA (1987) Distribution of Microcystis aeruginosa peptide toxin and interactions with hepatic microsomes in mice. Pharmacol Toxicol 60(3):187-191
5. Buxton ILO (2006) Pharmacokinetics and pharmacodynamics: the dynamics of drug absorption, distribution, action, and elimination. Goodman and Gilman's the pharmacological basis of therapeutics, 11th edn. McGraw-Hill Medical Publishing Division, New York, pp 1-40
6. Carbis CR, Simons JA, Mitchell GF, Anderson JW, McCauley I (1994) A biochemical profile for predicting the chronic exposure of sheep to Microscystis aeruginosa, an hepatotoxic species of blue-green alga. Res Vet Sci 57(3):310-316
7. Carbis C, Mitchell G, Anderson J, McCauley I (1996) The effects of microcystins on the serum biochemistry of carp, Cyprinus carpio L., when the toxins are administered by gavage, immersion and intraperitoneal routes. J Fish Dis 19(2):151-159
8. Carmichael WW, Beasley V, Bunner DL, Eloff JN, Falconer I, Gorham P, Harada K, Krishnamurthy T, Yu MJ, Moore RE (1988) Naming of cyclic heptapeptide toxins of cyanobacteria (blue-green algae). Toxicon Off J Int Soc Toxinol 26(11):971-973
9. Carmichael WW, Azevedo S, An JS, Molica R, Jochimsen EM, Lau S, Rinehart KL, Shaw GR, Eaglesham GK (2001) Human fatalities from cyanobacteria: chemical and biological evidence for cyanotoxins. Environ Health Perspect 109(7):663
10. Chen J, Zhang D, Xie P, Wang Q, Ma Z (2009) Simultaneous determination of microcystin contaminations in various vertebrates (fish, turtle, duck and water bird) from a large eutrophic Chinese lake, Lake Taihu, with toxic Microcystis blooms. Sci Total Environ 407(10):3317-3322
11. Chorus I, Bartram J (1999) Toxic cyanobacteria in water: a guide to public health significance, monitoring and management. E&FN Spon, London
12. Dawson R (1998) The toxicology of microcystins. Toxicon 36(7):953-962
13. Day Y, Myszka D (2002) Characterizing a drug's primary binding site on albumin. J Pharm Sci 92(2):333-343
14. Dennis M, Zhang M, Meng Y, Kadkhodayan M, Kirchhofer D, Combs D, Damico L (2002) Albumin binding as a general strategy for improving the pharmacokinetics of proteins. J Biol Chem 277(38):35035
15. Desmet WHO (1978) Study of serum-albumin and globulin of vertebrates. Acta zoologica et pathologica Antverpiensia 70:57-83
16. Dietrich D, Hoeger S (2005) Guidance values for microcystins in water and cyanobacterial supplement products (blue-green algal supplements): a reasonable or misguided approach? Toxicol Appl Pharmacol 203(3):273-289
17. Doolittle RF (1987) The evolution of the vertebrate plasma proteins. Biol Bull 172(3):269
18. Doumas BT (1975) Standards for total serum protein assays - a collaborative study. Clin Chem 21(8):1159
19. Doumas BT, Ard Watson W, Biggs HG (1971) Albumin standards and the measurement of serum albumin with bromcresol green. Clin Chim Acta 31(1):87-96
20. Francis G (1878) Poisonous Australian lake. Nature 18(444):11-12
21. Galtier P, Alvinerie M, Charpenteau JL (1981) The pharmacokinetic profiles of ochratoxin A in pigs, rabbits and chickens. Food Cosmet Toxicol 19:735-738
22. Gupta N, Pant SC, Vijayaraghavan R, Rao PVL (2003) Comparative toxicity evaluation of cyanobacterial cyclic peptide toxin microcystin variants (LR, RR, YR) in mice. Toxicology 188(2-3):285-296
23. Hagelberg S, Hult K, Fuchs R (1989) Toxicokinetics of ochratoxin A in several species and its plasma-binding properties. J Appl Toxicol 9(2):91-96
24. Honkanen RE, Zwiller J, Moore R, Daily SL, Khatra B, Dukelow M, Boynton A (1990) Characterization of microcystin-LR, a potent inhibitor of type 1 and type 2A protein phosphatases. J Biol Chem 265(32):19401
25. Hovda J, Linley TJ (2000) The potential application of hypothermia for anesthesia in adult Pacific salmon. N Am J Aquac 62(1):67-72
26. Ibelings B, Bruning K, De Jonge J, Wolfstein K, Pires L, Postma J, Burger T (2005) Distribution of microcystins in a lake foodweb: no evidence for biomagnification. Microb Ecol 49(4):487-500
27. Kanakis CD, Tarantilis PA, Polissiou MG, Diamantoglou S, Tajmir-Riahi HA (2006) Antioxidant flavonoids bind human serum albumin. J Mol Struct 798(1-3):69-74
28. Kotak B, Zurawell R, Prepas E, Holmes C (1996) Microcystin-LR concentration in aquatic food web compartments from lakes of varying trophic status. Can J Fish Aquat Sci 53(9):1974-1985
29. Kurtzhals P, Havelund S, Jonassen I, Kiehr B, Larsen U, Ribel U, Markussen J (1995) Albumin binding of insulins acylated with fatty acids: characterization of the ligand-protein interaction and correlation between binding affinity and timing of the insulin effect in vivo. Biochem J 312(Pt 3):725
30. Levy G, Yacobi A (1974) Effect of plasma protein binding on elimination of warfarin. J Pharm Sci 63(5):805-806
31. MacKintosh C, Beattie KA, Klumpp S, Cohen P, Codd GA (1990) Cyanobacterial microcystin-LR is a potent and specific inhibitor of protein phosphatases 1 and 2A from both mammals and higher plants. FEBS Lett 264(2):187-192
32. Metcalf V, Brennan S, Chambers G, George P (1998) The albumins of Chinook salmon (Oncorhynchus tshawytscha) and brown trout (Salmo trutta) appear to lack a propeptide. Arch Biochem Biophys 350(2):239-244
33. Meuldermans WE, Hurkmans RM, Heykants JJ (1982) Plasma protein binding and distribution of fentanyl, sufentanil, alfentanil and lofentanil in blood. Arch Int Pharmacodyn Ther 257(1):4-19
34. Nasri H, El Herry S, Bouaïcha N (2008) First reported case of turtle deaths during a toxic Microcystis spp. bloom in Lake Oubeira, Algeria. Ecotoxicol Environ Saf 71(2):535-544
35. Nishiwaki-Matsushima R, Ohta T, Nishiwaki S, Suganuma M, Kohyama K, Ishikawa T, Carmichael WW, Fujiki H (1992) Liver tumor promotion by the cyanobacterial cyclic peptide toxin microcystin-LR. J Cancer Res Clin Oncol 118(6):420-424
36. Råbergh CMI, Bylund G, Eriksson JE (1991) Histopathological effects of microcystin-LR, a cyclic peptide toxin from the cyanobacterium (blue-green alga) Microcystis aeruginosa on common carp (Cyprinus carpio L.). Aquat Toxicol 20(3):131-145
37. Ramanan S, Tang J, Velayudhan A (2000) Isolation and preparative purification of microcystin variants. J Chromatogr A 883(1-2):103-112
38. Robinson NA (1990) Toxicokinetics of (3H) microcystin-LR in mice. DTIC Document
39. Robinson NA, Miura GA, Matson CF, Dinterman RE, Pace JG (1989) Characterization of chemically tritiated microcystin-LR and its distribution in mice. Toxicon 27(9):1035-1042
40. Robinson NA, Pace JG, Matson CF, Miura GA, Lawrence WB (1991) Tissue distribution, excretion and hepatic biotransformation of microcystin-LR in mice. J Pharmacol Exp Ther 256(1):176-182
41. Tencalla FG, Dietrich DR, Schlatter C (1994) Toxicity of Microcystis aeruginosa peptide toxin to yearling rainbow trout (Oncorhynchus mykiss). Aquat Toxicol 30(3):215-224
42. Wang Q, Xie P, Chen J, Liang G (2008) Distribution of microcystins in various organs (heart, liver, intestine, gonad, brain, kidney and lung) of Wistar rat via intravenous injection. Toxicon 52(6):721-727
43. Williams D, Kent M, Andersen R, Klix H, Holmes C (1995) Tissue distribution and clearance of tritium-labeled dihydromicrocystin-LR epimers administered to Atlantic salmon via intraperitoneal injection. Toxicon 33(2):125-131
44. Williams D, Craig M, Dawe S, Kent M, Andersen R, Holmes C (1997) 14C-labelled microcystin-LR administered to Atlantic salmon via intraperitoneal injection provides in vivo evidence for covalent binding of microcystin-LR in salmon livers. Toxicon 35(6):985-989
45. Wright J, Boudinot F, Ujhelyi M (1996) Measurement and analysis of unbound drug concentrations. Clin Pharmacokinet 30(6):445
46. Xie L, Xie P, Ozawa K, Honma T, Yokoyama A, Park H (2004) Dynamics of microcystins-LR and-RR in the phytoplanktivorous silver carp in a sub-chronic toxicity experiment. Environ Pollut 127(3):431-439
47. Yoshizawa S, Matsushima R, Watanabe MF, Harada K, Ichihara A, Carmichael WW, Fujiki H (1990) Inhibition of protein phosphatases by microcystis and nodularin associated with hepatotoxicity. J Cancer Res Clin Oncol 116(6):609-614
48. Yuwiler A, Oldendorf W, Geller E, Braun L (2006) Effect of albumin binding and amino acid competition on tryptophan uptake into brain1. J Neurochem 28(5):1015-1023
49. Zhang D, Xie P, Liu Y, Qiu T (2009) Transfer, distribution and bioaccumulation of microcystins in the aquatic food web in Lake Taihu, China, with potential risks to human health. Sci Total Environ 407(7):2191-2199