Morphological changes of bladder mucosa in patients who underwent instillation with combined sodium hyaluronic acid-chondroitin sulphate (ialuril®)

Urologia Internationalis

Volumn 91, Issue 1, 2013, Pages 81-88

  Costantini, E ^a   Lazzeri, M ^a   Pistolesi, D ^b   Del Zingaro, M ^a   Frumenzio, E ^a   Boni, A ^a   Pietropaolo, A ^a   Fragala E ^c   Porena, M ^a  

^a SANTA MARIA DELLA MISERICORDIA HOSPITAL   (Italy)

^b UNIVERSITY HOSPITAL OF PISA   (Italy)

^c UNIVERSITY OF CATANIA   (Italy)

Author keywords

Bladder pain syndrome interstitial cystitis; Chondroitin sulphate; Cystoscopy; Hyaluronic acid; Recurrent urinary tract infections

Indexed keywords

CHONDROITIN SULFATE; HYALURONIC ACID; IALURIL; LALURIL; UNCLASSIFIED DRUG;

ARTICLE; BLADDER EPITHELIUM; BLADDER MUCOSA; BLADDER PAIN SYNDROME; CLINICAL ARTICLE; CYSTALGIA; CYSTOSCOPY; DRUG INSTILLATION; DRUG WITHDRAWAL; FEMALE; HUMAN; HYPEREMIA; INTERSTITIAL CYSTITIS; MORPHOLOGY; OUTCOME ASSESSMENT; PATIENT SATISFACTION; PRIORITY JOURNAL; RECURRENT INFECTION; URINARY TRACT INFECTION; VISUAL ANALOG SCALE; ADULT; BLADDER NECK; IALURIL; MIDDLE AGED; PATIENT ASSESSMENT; URINALYSIS; UROLOGICAL IMPLANT;

ADULT; AGED; CHONDROITIN SULFATES; CYSTITIS; CYSTITIS, INTERSTITIAL; CYSTOSCOPY; DRUG COMBINATIONS; ENDOSCOPY; FEMALE; GLYCOSAMINOGLYCANS; HUMANS; HYALURONIC ACID; MIDDLE AGED; MUCOUS MEMBRANE; URINARY BLADDER; URINARY BLADDER DISEASES; URINARY TRACT INFECTIONS; UROTHELIUM;

EID: 84880916192     PISSN: 00421138     EISSN: 14230399     Source Type: Journal    
DOI: 10.1159/000345047     Document Type: Article

References (27)

1. Cerruto MA, Asimakopoulos AD, Artibani W, et al: Insight into new potential targets for the treatment of overactive bladder and detrusor overactivity. Urol Int 2012; 89: 1-8
2. Bassi PF, Costantini E, Foley S, Palea S: Glycosaminoglycan therapy for bladder diseases: Emerging new treatments. Eur Urol Suppl 2011; 10: 451-459
3. Lazzeri M, Montorsi F: The therapeutic challenge of 'chronic cystitis': Search well, work together, and gain results. Eur Urol 2011; 60: 78-80
4. Hinkel A, Strumberg D, Noldus J, Pannek J: Observation of de novo bladder dysfunction under treatment with Her2-neu antibodies. Urol Int 2011; 86: 80-84
5. Damiano R, Quarto G, Bava I, et al: Prevention of recurrent urinary tract infections by intravesical administration of hyaluronic acid and chondroitin sulphate: A placebocontrolled randomised trial. Eur Urol 2011; 59: 645-651
6. van de Merwe JP, Nordling J, Bouchelouche P, et al: Diagnostic criteria, classification, and nomenclature for painful bladder syndrome/ interstitial cystitis: An ESSIC proposal. Eur Urol 2008; 53: 60-67
7. Parziani S, Costantini E, Petroni PA, Ursini M, Porena M: Urethral syndrome: Clinical results with antibiotic alone or combined with estrogen. Eur Urol 1994; 26: 115-119
8. Costantini E, Zucchi A, Del Zingaro M, Mearini L: Treatment of urethral syndrome: A prospective randomized study with Nd:YAG laser. Urol Int 2006; 76: 134-138
9. Grabe M, Bjerklund-Johansen TE, Botto H, Wullt B, Çek M, Naber KG, Pickard RS, Tenke P, Wagenlehner F: Guidelines on Urological Infections by the EAU, 2012, pp 1-110
10. Parsons CL: A model for the function of glycosaminoglycans in the urinary tract. World J Urol 1994; 12: 38-42
11. Constantinides C, Manousakas T, Nikolopoulos P, et al: Prevention of recurrent bacterial cystitis by intravesical administration of hyaluronic acid: A pilot study. BJU Int 2004; 93: 1262-1266
12. Lipovac M, Kurz C, Reithmayr F, et al: Prevention of recurrent bacterial urinary tract infections by intravesical instillation of hyaluronic acid. Int J Gynaecol Obstet 2007; 96: 192-195
13. De Vita D, Giordano S: Effectiveness of intravesical hyaluronic acid/chondroitin sulfate in recurrent bacterial cystitis: A randomized study. Int Urogynecol J 2012, Epub ahead of print
14. Korotkova N, Yarova-Yarovaya Y, Tchesnokova V, Yazvenko N, Carl MA, Stapleton AE, Moseley SL: Escherichia coli DraE adhesinassociated bacterial internalization by epithelial cells is promoted independently by decay-Accelerating factor and carcinoembryonic antigen-related cell adhesion molecule binding and does not require the DraD invasin. Infect Immun 2008; 76: 3869-3880
15. Bower JM, Eto DS, Mulvey MA: Covert operations of uropathogenic Escherichia coli within the urinary tract. Traffic 2005; 6: 18-31
16. Mulvey MA, Schilling JD, Hultgren SJ: Establishment of a persistent Escherichia coli reservoir during the acute phase of a bladder infection. Infect Immun 2001; 69: 4572-4579
17. Lai Y, Wu S, Ni L, et al: Ketamine-Associated urinary tract dysfunction: An underrecognized clinical entity. Urol Int 2012; 89: 93-96
18. Toft BR, Nordling J: Recent developments of intravesical therapy of painful bladder syndrome/ interstitial cystitis: A review. Curr Opin Urol 2006; 6: 268-272
19. Iavazzo C, Athanasiou S, Pitsouni E, Falagas ME: Hyaluronic acid: An effective alternative treatment of interstitial cystitis, recurrent urinary tract infections, and hemorrhagic cystitis? Eur Urol 2007; 51: 1534-1541
20. Morales A, Emerson L, Nickel JC: Treatment of refractory interstitial cystitis. Int Urogynecol J Pelvic Floor Dysfunct 1996; 7: 215-220
21. Engelhardt PF, Morakis N, Daha LK, Esterbauer B, Riedl CR: Long-term results of intravesical hyaluronan therapy in bladder pain syndrome/interstitial cystitis. Int Urogynecol J 2001; 22: 401-405
22. Palylyk-Colwell E: Chondroitin sulfate for interstitial cystitis. Issues Emerg Health Technol 2006; 84: 1-4
23. Steinhoff G: The efficacy of chondroitin sulphate in treating interstitial cystitis. Eur Urol Suppl 2003; 2: 14-16
24. Nickel JC, Egerdie B, Downey J, et al: A reallife multicentre clinical practice study to evaluate the efficacy and safety of intravesical chondroitin sulphate for the treatment of interstitial cystitis. BJU Int 2008; 103:56-60
25. Porru D, Cervigni M, Nasta L, et al: Results of endovesical hyaluronic acid/chondroitin sulfate in the treatment of interstitial cystitis/ painful bladder syndrome. Rev Recent Clin Trials 2008; 3: 126-129
26. Cervigni M, Natale F, Nasta L, Padoa A, Voi RL, Porru D: A combined intravesical therapy with hyaluronic acid and chondroitin for refractory painful bladder syndrome/interstitial cystitis. Int Urogynecol J Pelvic Floor Dysfunct 2008; 19: 943-947
27. Cervigni M, Natale F, Nasta L, Mako A: Intravesical hyaluronic acid and chondroitin sulphate for bladder pain syndrome/interstitial cystitis: Long-term treatment results. Int Urogynecol J Pelvic Floor Dysfunct 2012; 23: 1187-1192