Identification of haemophilus influenzae clones associated with invasive disease a decade after introduction of H. influenzae serotype b vaccination in Italy

Clinical and Vaccine Immunology

Volumn 20, Issue 8, 2013, Pages 1223-1229

  Giufrè, Maria ^a   Cardines, Rita ^a   Accogli, Marisa ^a   Pardini, Manuela ^a   Cerquetti, Marina ^a  

^a ISTITUTO SUPERIORE DI SANITÀ   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AMPICILLIN; AZITHROMYCIN; BETA LACTAMASE; CEFOTAXIME; CHLORAMPHENICOL; CIPROFLOXACIN; HAEMOPHILUS VACCINE; IMMUNOGLOBULIN A;

ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL STRAIN; BACTERIUM IDENTIFICATION; BACTERIUM ISOLATION; DIFFUSION; DISEASE ASSOCIATION; GENETIC HETEROGENEITY; GENETIC POLYMORPHISM; GENOTYPE; HAEMOPHILUS INFECTION; HAEMOPHILUS INFLUENZAE; HUMAN; ITALY; MINIMUM INHIBITORY CONCENTRATION; MOLECULAR CLONING; MULTILOCUS SEQUENCE TYPING; NONHUMAN; NUCLEOTIDE SEQUENCE; PHYLOGENY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; SEROTYPE; SEROTYPING;

BACTEREMIA; BACTERIAL CAPSULES; BETA-LACTAMASES; GENES, BACTERIAL; GENOTYPE; HAEMOPHILUS INFECTIONS; HAEMOPHILUS INFLUENZAE; HAEMOPHILUS VACCINES; HUMANS; ITALY; MENINGITIS, BACTERIAL; MICROBIAL SENSITIVITY TESTS; MOLECULAR EPIDEMIOLOGY; MULTILOCUS SEQUENCE TYPING; SEROTYPING; VACCINATION; VACCINES, CONJUGATE;

EID: 84880913322     PISSN: 15566811     EISSN: 1556679X     Source Type: Journal    
DOI: 10.1128/CVI.00028-13     Document Type: Article

References (32)

1. Pittman M. 1931. Variation and type specificity in the bacterial species Haemophilus influenzae. J. Exp. Med. 53:471-492.
2. Falla TJ, Crook DWM, Brophy LN, Maskell D, Kroll JS, Moxon ER. 1994. PCR for capsular typing of Haemophilus influenzae. J. Clin. Microbiol. 32:2382-2386.
3. Giufrè M, Cardines R, Caporali MG, Accogli M, D'Ancona F, Cerquetti M. 2011. Ten years of Hib vaccination in Italy: prevalence of nonencapsulated Haemophilus influenzae among invasive isolates and the possible impact on antibiotic resistance. Vaccine 29:3857-3862.
4. Ladhani S, Slack MP, Heath PT, von Gottberg A, Chandra M, Ramsay ME, European Union Invasive Bacterial Infection Surveillance Participants. 2010. Invasive Haemophilus influenzae disease, Europe, 1996- 2006. Emerg. Infect. Dis. 16:455-463.
5. Dworkin MS, Park L, Borchardt SM. 2007. The changing epidemiology of invasive Haemophilus influenzae disease, especially in persons -65 years old. Clin. Infect. Dis. 44:810-816.
6. Kalies H, Siedler A, Grondahl B, Grote V, Milde-Busch A, von Kries R. 2009. Invasive Haemophilus influenzae infections in Germany: impact of non-type b serotypes in the post-vaccine era. BMC Infect. Dis. 9:45. doi: 10.1186/1471-2334-9-45.
7. Resman F, Ristovski M, Forsgren A, Kaijser B, Kronvall G, Medstrand P, Melander E, Odenholt I, Riesbeck K. 2012. Increase of -lactamresistant invasive Haemophilus influenzae in Sweden, 1997 to 2010. Antimicrob. Agents Chemother. 56:4408-4415.
8. Tristram S, Jacobs MR, Appelbaum PC. 2007. Antimicrobial resistance in Haemophilus influenzae. Clin. Microbiol. Rev. 20:368-389.
9. Tristram SG, Hawes R, Souprounov J. 2005. Variation in selected regions of blaTEM genes and promoters in Haemophilus influenzae. J. Antimicrob. Chemother. 56:481-484.
10. Cerquetti M, Cardines R, Giufrè M, Mastrantonio P, HI Study Group. 2004. Antimicrobial susceptibility of Haemophilus influenzae strains isolated from invasive disease in Italy. J. Antimicrob. Chemother. 54:1139- 1143.
11. Meats E, Feil EJ, Stringer S, Cody AJ, Goldstein R, Kroll JS, Popovic T, Spratt BG. 2003. Characterization of encapsulated and noncapsulated Haemophilus influenzae and determination of phylogenetic relationships by multilocus sequence typing. J. Clin. Microbiol. 41:1623-1636.
12. Tamura K, Peterson D, Peterson N, Stecher G, Nei M, Kumar S. 2011. MEGA5: molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods. Mol. Biol. Evol. 28:2731-2739.
13. Cerquetti M, Ciofi degli Atti ML, Renna G, Tozzi AE, Garlaschi ML, Mastrantonio P, HI Study Group. 2000. Characterization of non-type B Haemophilus influenzae strains isolated from patients with invasive disease. J. Clin. Microbiol. 38:4649-4652.
14. Cardines R, Giufrè M, Mastrantonio P, Ciofi degli Atti ML, Cerquetti M. 2007. Nontypeable Haemophilus influenzae meningitis in children: phenotypic and genotypic characterization of isolates. Pediatr. Infect. Dis. J. 26:577-582.
15. Fernaays MM, Lesse AJ, Cai X, Murphy TF. 2006. Characterization of igaB, a second immunoglobulin A1 protease gene in nontypeable Haemophilus influenzae. Infect. Immun. 74:5860-5870.
16. Shuel ML, Karlowsky KE, Law DK, Tsang RS. 2011. Nonencapsulated or nontypeable Haemophilus influenzae are more likely than their encapsu- lated or serotypeable counterparts to have mutations in their fucose operon. Can. J. Microbiol. 57:982-986.
17. Smith-Vaughan HC, Sriprakash KS, Leach AJ, Mathews JD, Kemp DJ. 1998. Low genetic diversity of Haemophilus influenzae type b compared to nonencapsulated H. influenzae in a population in which H. influenzae is highly endemic. Infect. Immun. 66:3403-3409.
18. Erwin AL, Sandstedt SA, Bonthuis PJ, Geelhood JL, Nelson KL, Unrath WC, Diggle MA, Theodore MJ, Pleatman CR, Mothershed EA, Sacchi CT, Mayer LW, Gilsdorf JR, Smith AL. 2008. Analysis of genetic relatedness of Haemophilus influenzae isolates by multilocus sequence typing. J. Bacteriol. 190:1473-1483.
19. Schumacher SK, Marchant CD, Loughlin AM, Bouchet V, Stevenson A, Pelton SI. 2012. Prevalence and genetic diversity of nontypeable Haemophilus influenzae in the respiratory tract of infants and primary caregivers. Pediatr. Infect. Dis. J. 31:145-149.
20. Kaur R, Chang A, Xu Q, Casey JR, Pichichero ME. 2011. Phylogenetic relatedness and diversity of non-typable Haemophilus influenzae in the nasopharynx and middle ear fluid of children with acute otitis media. J. Med. Microbiol. 60:1841-1848.
21. Shuel M, Law D, Skinner S, Wylie J, Karlowsky J, Tsang RS. 2010. Characterization of nontypeable Haemophilus influenzae collected from respiratory infections and invasive disease cases in Manitoba, Canada. FEMS Immunol. Med. Microbiol. 58:277-284.
22. Sill ML, Law DK, Zhou J, Skinner S, Wylie J, Tsang RS. 2007. Population genetics and antibiotic susceptibility of invasive Haemophilus influenzae in Manitoba, Canada, from 2000 to 2006. FEMS Immunol. Med. Microbiol. 51:270-276.
23. Musser JM, Kroll JS, Moxon ER, Selander RK. 1988. Clonal population structure of encapsulated Haemophilus influenzae. Infect. Immun. 56: 1837-1845.
24. Schouls LM, van der Ende A, van de Pol I, Schot C, Spanjaard L, Vauterin P, Wilderbeek D, Witteveen SJ. 2005. Increase in genetic diversity of Haemophilus influenzae serotype b (Hib) strains after introduction of Hib vaccination in The Netherlands. J. Clin. Microbiol. 43:2741- 2749.
25. Ladhani SN, Collins S, Vickers A, Litt DJ, Crawford C, Ramsay ME, Slack MP. 2012. Invasive Haemophilus influenzae serotype e and f disease, England and Wales. Emerg. Infect. Dis. 18:725-732.
26. Musser JM, Kroll JS, Moxon ER, Selander RK. 1988. Evolutionary genetics of the encapsulated strains of Haemophilus influenzae. Proc. Natl. Acad. Sci. U. S. A. 85:7758-7762.
27. Giufrè M, Cardines R, Mastrantonio P, Cerquetti M. 2010. Genetic characterization of the capsulation locus of Haemophilus influenzae serotype e. J. Clin. Microbiol. 48:1404-1407.
28. St Geme JW, III, Kumar VV, Cutter D, Barenkamp SJ. 1998. Prevalence and distribution of thehmwand hia genes and theHMWand Hia adhesins among genetically diverse strains of nontypeable Haemophilus influenzae. Infect. Immun. 66:364-368.
29. Ecevit IZ, McCrea KW, Pettigrew MM, Sen A, Marrs CF, Gilsdorf, 2004. Prevalence of the hifBC, hmw1A, hmw2A, hmwC, and hia genes in Haemophilus influenzae isolates. J. Clin. Microbiol. 42:3065-3072.
30. Kilian M, Mestecky J, Schrohenloher JE. 1979. Pathogenic species of the genus Haemophilus and Streptococcus pneumoniae produce immunoglobulin A1 protease. Infect. Immun. 26:143-149.
31. Murphy TF, Lesse AJ, Kirkham C, Zhong H, Sethi S, Munson RS Jr. 2011. A clonal group of nontypeable Haemophilus influenzae with two IgA proteases is adapted to infection in chronic obstructive pulmonary disease. PLoS One 6:e25923. doi:10.1371/journal.pone.0025923.
32. Vogel L, van Alphen L, Geluk F, Troelstra A, Martin E, Bredius R, Eijk P, Jansen H, Dankert J. 1994. Quantitative flow cytometric analysis of opsonophagocytosis and killing of nonencapsulated Haemophilus influenzae by human polymorphonuclear leukocytes. Clin. Diagn. Lab. Immunol. 1:394-400.