The effect of a biphasic injectable bone substitute on the interface strength in a rabbit knee prosthesis model

Journal of Orthopaedic Surgery and Research

Volumn 8, Issue 1, 2013, Pages

  Zampelis, Vasilis ^a,b   Tägil, Magnus ^a   Lidgren, Lars ^a   Isaksson, Hanna ^a,c   Atroshi, Isam ^a,b   Wang, Jian Sheng ^a  

^a LUND UNIVERSITY   (Sweden)

^b Hassleholm Hospital   (Sweden)

^c UNIVERSITY OF EASTERN FINLAND   (Finland)

Author keywords

Calcium sulfate; Histomorphometry; Hydroxyapatite; Injectable bone substitute; Interface strength

Indexed keywords

CALCIUM SULFATE; CERAMENT; HYDROXYAPATITE; BONE FILLER; BONE PROSTHESIS; DRUG COMBINATION;

ANIMAL; ARTICLE; BONE PROSTHESIS; DEVICE REMOVAL; DISEASE MODEL; DRUG COMBINATION; EVALUATION STUDY; INTRAARTICULAR DRUG ADMINISTRATION; KNEE ARTHROPLASTY; KNEE PROSTHESIS; MATERIALS TESTING; MECHANICAL STRESS; METHODOLOGY; MICRO-COMPUTED TOMOGRAPHY; PATHOLOGY; PROSTHESIS FAILURE; RABBIT; RADIOGRAPHY; TIBIA; ADMINISTRATION AND DOSAGE; PROCEDURES; THERAPEUTIC USE;

ANIMALS; ARTHROPLASTY, REPLACEMENT, KNEE; BONE SUBSTITUTES; CALCIUM SULFATE; DEVICE REMOVAL; DISEASE MODELS, ANIMAL; DRUG COMBINATIONS; DURAPATITE; INJECTIONS, INTRA-ARTICULAR; KNEE PROSTHESIS; MATERIALS TESTING; PROSTHESIS FAILURE; RABBITS; STRESS, MECHANICAL; TIBIA; X-RAY MICROTOMOGRAPHY;

EID: 84880882981     PISSN: None     EISSN: 1749799X     Source Type: Journal    
DOI: 10.1186/1749-799x-8-25     Document Type: Article

References (19)

1. Weiss RJ, Stark A, Kärrholm J: A modular cementless stem vs. cemented long-stem prostheses in revision surgery of the hip. A population-based study from the Swedish Hip Arthroplasty Register. Acta Orthop 2011, 82:136-142
2. Holt G, Hook S, Hubble M: Revision total hip arthroplasty: the femoral side using cemented implants. International Orthopaedics (SICOT) 2011, 35:267-273
3. Oonishi H, Hench LL, Wilson J, Sugihara F, Tsuji E, Kushitani S, Iwaki H: Comparative bone growth behavior in granules of bioceramic materials of various sizes. J Biomed Mater Res 1999, 44:31-43
4. Abramo A, Geijer M, Kopylov P, Tägil M: Osteotomy of distal radius fracture malunion using a fast remodeling bone substitute consisting of calcium sulphate and calcium phosphate. J Biomed Mater Res B Appl Biomater 2010, 92:281-286
5. Hatten HP Jr, Voor MJ: Bone healing using a bi-phasic ceramic bone substitute demonstrated in human vertebroplasty and with histology in rabbit cancellous bone defect model. Interv Neuroradiol 2012, 18:105-113
6. Nilsson M, Wang JS, Wielanek L, Tanner KE, Lidgren L: Biodegradation and biocompatibility of a calcium sulphate-hydroxyapatite bone substitute. J Bone Joint Surg 2004, 86:120-125
7. Watson JT: The use of an injectable bone graft substitute in tibial metaphyseal fractures. Orthopedics 2004, 27(1 Suppl):s103-s107
8. Jansen J, Ooms E, Verdonschot N, Wolke J: Injectable calcium phosphate cement for bone repair and implant fixation. OrthopClin North Am 2005, 36:89-95
9. Wang JS, Goodman S, Aspenberg: Bone formation in the presence of phagocytosable hydroxyapatite particles. Clin Orthop 1994, 304:272-279
10. Wang JS, Magnus T, Aspenberg P: Load-bearing increases new bone formation in impacted and morselized allografts. Clin Orthop 2000, 378:274-281
11. Nilsson M, Fernandez E, Sarda S, Lidgren L, Planell JA: Characterization of a novel calcium phosphate/sulphate bone cement. J Biomed Mater Res 2002, 61:600-607
12. Jeppsson C, Astrand J, Tägil M, Aspenberg P: A combination of bisphosphonate and BMP additives in impacted bone allografts. Acta Orthop Scand 2003, 74:483-489
13. Tägil M: The morselized and impacted bone graft. Animal experiments on protein, impaction and load. Acta Orthop Scand 2000, 71(290):1-40
14. Ullmark G, Linder L: Histology of the femur after cancellous impaction grafting using a Charnley prosthesis. Arch Orthop Trauma Surg 1998, 117:170-172
15. McGee MA, Findlay DM, Howie DW, Carbone A, Ward P, Stamenkov R, Page TT, Bruce WJ, Wildenauer CI, Toth C: The use of OP-1 in femoral impaction grafting in a sheep model. J Orthop Res 2004, 22:1008-1015
16. Kärrholm J, Hourigan P, Timperley J, Razaznejad R: Mixing bone graft with OP-1 does not improve cup or stem fixation in revision surgery of the hip: 5-year follow-up of 10 acetabular and 11 femoral study cases and 40 control cases. Acta Orthop 2006, 77:39-48
17. Kamiya N: The role of BMPs in bone anabolism and their potential targets SOST and DKK1. Curr Mol Pharmacol 2012, 5:153-163
18. Kesteris U, Aspenberg P: Rinsing morcellised bone grafts with bisphosphonate solution prevents their resorption. A prospective randomised double-blinded study. J Bone Joint Surg Br 2006, 88:993-996
19. Marcia S, Boi C, Dragani M, Marini S, Marras M, Piras E, Anselmetti GC, Masala S: Effectiveness of a bone substitute (CERAMENT™) as an alternative to PMMA in percutaneous vertebroplasty: 1-year follow-up on clinical outcome. Eur Spine J 2012, 21(Suppl 1):112-118