Glycolipid Transfer Protein Expression Is Affected by Glycosphingolipid Synthesis

PLoS ONE

Volumn 8, Issue 7, 2013, Pages

  Kjellberg, Matti A ^a   Mattjus, Peter ^a  

^a ÅBO AKADEMI UNIVERSITY   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

BREFELDIN A; GALACTOSYLCERAMIDE; GLUCOSYLCERAMIDE; GLYCOLIPID TRANSFER PROTEIN; GLYCOSPHINGOLIPID; LACTOSYLCERAMIDE; LIPID TRANSFER PROTEIN; MESSENGER RNA; MONENSIN; UNCLASSIFIED DRUG;

ARTICLE; CELL FUSION; CELL STRESS; CONTROLLED STUDY; DOWN REGULATION; ENDOPLASMIC RETICULUM; GENE EXPRESSION; GLUCOSYLCERAMIDE GENE; GLYCOLIPID TRANSFER PROTEIN GENE; GOLGI COMPLEX; HEAT SHOCK; HUMAN; HUMAN CELL; LIPID ANALYSIS; LIPID DEGRADATION; LIPID STORAGE; LIPID TRANSPORT; LIPOGENESIS; LYSOSOME; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TRANSPORT;

EID: 84880848080     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0070283     Document Type: Article

References (52)

1. Degroote S, Wolthoorn J, van Meer G, (2004) The cell biology of glycosphingolipids. Semin Cell Dev Biol 15: 375-387.
2. Futerman AH, Pagano RE, (1991) Determination of the intracellular sites and topology of glucosylceramide synthesis in rat liver. Biochem J 280: 295-302.
3. Jeckel D, Karrenbauer A, Burger KNJ, van Meer G, Wieland FT, (1992) Glucosylceramide is synthesized at the cytosolic surface of various golgi subfractions. J Cell Biol 117: 259-267.
4. Burger KNJ, van der Bijl P, van Meer G, (1996) Topology of sphingolipid galactosyltransferases in ER and Golgi: Transbilayer movement of monohexosyl sphingolipids is required for higher glycosphingolipid biosynthesis. J Cell Biol 133: 15-28.
5. Huitema K, Van Den Dikkenberg J, Brouwers JF, Holthuis JCM, (2004) Identification of a family of animal sphingomyelin synthases. EMBO J 23: 33-44.
6. Wennekes T, van den Berg RJ, Boot RG, van der Marel GA, Overkleeft HS, et al. (2009) Glycosphingolipids- Nature, function, and pharmacological modulation. Angewandte Chemie 48: 8848-8869.
7. Basu S, Kaufman B, Roseman S, (1973) Enzymatic synthesis of glucocerebroside by a glucosyltransferase from embryonic chicken brain. J Biol Chem 248: 1388-1394.
8. Sprong H, Kruithof B, Leijendekker R, Slot JW, van Meer G, et al. (1998) UDP-galactose-ceramide galactosyltransferase is a class I integral membrane protein of the endoplasmic reticulum. J Biol Chem 273: 25880-25888.
9. Bosio A, Binczek E, Le Beau MM, Fernald AA, Stoffel W, (1996) The human gene CGT encoding the UDP-galactose ceramide galactosyl transferase (cerebroside synthase): cloning, characterization, and assignment to human chromosome 4, band q26. Genomics 34: 69-75.
10. Chatterjee S, Castiglione E, (1987) UDPgalactose:glucosylceramide beta 1->4-galactosyltransferase activity in human proximal tubular cells from normal and familial hypercholesterolemic homozygotes. Biochim Biophys Acta 923: 136-142.
11. Allende ML, Li J, Darling DS, Worth CA, Young WW Jr, (2000) Evidence supporting a late Golgi location for lactosylceramide to ganglioside GM3 conversion. Glycobiology 10: 1025-1032.
12. Lannert H, Gorgas K, Meissner I, Wieland FT, Jeckel D, (1998) Functional organization of the Golgi apparatus in glycosphingolipid biosynthesis Lactosylceramide and subsequent glycosphingolipids are formed in the lumen of the late Golgi. J Biol Chem 273: 2939-2946.
13. Trinchera M, Ghidoni R, (1989) Two glycosphingolipid sialyltransferases are localized in different sub-Golgi compartments in rat liver. J Biol Chem 264: 15766-15769.
14. Tuuf J, Mattjus P, (2007) Human glycolipid transfer protein-intracellular localization and effects on the sphingolipid synthesis. Biochim Biophys Acta 1771: 1353-1363.
15. Yamada K, Abe A, Sasaki T, (1986) Glycolipid transfer protein from pig brain transfers glycolipids with beta-linked sugars but not with alpha-linked sugars at the sugar-lipid linkage. Biochim Biophys Acta 879: 345-349.
16. Mattjus P, (2009) Glycolipid transfer proteins and membrane interaction. Biochim Biophys Acta 1788: 267-272.
17. Brown RE, Stephenson FA, Markello T, Barenholz Y, Thompson TE, (1985) Properties of a specific glycolipid transfer protein from bovine brain. Chem Phys Lipids 38: 79-93.
18. Brown RE, Mattjus P, (2007) Glycolipid transfer protein- Review. Biochim Biophys Acta 1771: 746-776.
19. Malinina L, Malakhova ML, Teplov A, Brown RE, Patel DJ, (2004) Structural basis for glycosphingolipid transfer specificity. Nature 430: 1048-1053.
20. West G, Viitanen L, Alm C, Mattjus P, Salminen TA, et al. (2008) Identification of a glycosphingolipid transfer protein GLTP1 in Arabidopsis thaliana. FEBS J 275: 3421-3437.
21. Saupe SJ, Descamps C, Turcq B, Begueret J, (1994) Inactivation of the Podospora anserina vegetative incompatibility locus het-c, whose product resembles a glycolipid transfer protein, drastically impairs ascospore production. Proc Natl Acad Sci U S A 91: 5927-5931.
22. Brodersen P, Petersen M, Pike HM, Olszak B, Skov S, et al. (2002) Knockout of Arabidopsis accelerated-cell-death 11 encoding a sphingosine transfer protein causes activation of programmed cell death and defense. Genes Dev 16: 490-502.
23. Godi A, Di Campli A, Konstantakopoulos A, Di Tullio G, Alessi DR, et al. (2004) FAPPs control Golgi-to-cell-surface membrane traffic by binding to ARF and PtdIns(4)P. Nat Cell Biol 6: 393-404.
24. D'Angelo G, Polishchuk E, Di Tullio G, Santoro M, Di Campli A, et al. (2007) Glycosphingolipid synthesis requires FAPP2 transfer of glucosylceramide. Nature 449: 62-67.
25. Malakhova ML, Malinina L, Pike HM, Kanack AT, Patel DJ, et al. (2005) Point mutational analysis of the liganding site in human glycolipid transfer protein: Functionally of the complex. J Biol Chem 280: 26312-26220.
26. Tuuf J, Wistbacka L, Mattjus P, (2009) The glycolipid transfer protein interacts with the vesicle-associated membrane protein-associated protein VAP-A. Biochem Biophys Res Commun 388: 395-399.
27. Mikitova V, Levine TP, (2012) Analysis of the key elements of FFAT-like motifs identifies new proteins that potentially bind VAP on the ER, including two AKAPs and FAPP2. PloS one 7: e30455.
28. Pewzner-Jung Y, Ben-Dor S, Futerman AH, (2006) When Do Lasses (Longevity Assurance Genes) Become CerS (Ceramide Synthases)?: Insights into the regulation of ceramide synthesis. J Biol Chem 281: 25001-25005.
29. Stiban J, Tidhar R, Futerman AH, (2010) Ceramide synthases: roles in cell physiology and signaling. Adv Exp Med Biol 688: 60-71.
30. van Echten G, Iber H, Stotz H, Takatsuki A, Sandhoff K, (1990) Uncoupling of ganglioside biosynthesis by Brefeldin A. Eur J Cell Biol. 51: 135-139.
31. Farrer RG, Warden MP, Quarles RH, (1995) Effects of brefeldin A on galactosphingolipid synthesis in an immortalized Schwann cell line: evidence for different intracellular locations of galactosylceramide sulfotransferase and ceramide galactosyltransferase activities. J Neurochem 65: 1865-1873.
32. Newburg DS, Yatziv S, McCluer RH, Raghavan S, (1986) beta-Glucosidase inhibition in murine peritoneal macrophages by conduritol-B-epoxide: an in vitro model of the Gaucher cell. Biochim Biophys Acta 877: 121-126.
33. Miyake Y, Kozutsumi Y, Nakamura S, Fujita T, Kawasaki T, (1995) Serine palmitoyltransferase is the primary target of a sphingosine-like immunosuppressant, ISP-1/myriocin. Biochem Biophys Res Commun 211: 396-403.
34. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ, (1951) Protein measurment with the Folin phenol reagent. J Biol Chem 193: 265-275.
35. Abramoff MD, Magalhaes PJ, Ram SJ, (2004) Image Processing with ImageJ. Biophotonics International 11: 36-42.
36. Klausner RD, Donaldson JG, Lippincott-Schwartz J, (1992) Brefeldin A: insights into the control of membrane traffic and organelle structure. J Cell Biol 116: 1071-1080.
37. Maccioni HJF, Daniotti JL, Martina JA, (1999) Organization of ganglioside synthesis in the Golgi apparatus. Biochim Biophys Acta 1437: 101-101.
38. Kallen KJ, Quinn PJ, Allan D, (1993) Effects of brefeldin A on sphingomyelin transport and lipid synthesis in BHK21 cells. Biochem J 289: 307-312.
39. Schwarzmann G, Sandhoff K, (1990) Metabolism and intracellular transport of glycosphingolipids. Biochemistry 29: 10865-10871.
40. Duksin D, Mahoney WC, (1982) Relationship of the structure and biological activity of the natural homologues of tunicamycin. J Biol Chem 257: 3105-3109.
41. Saito K, Takakuwa N, Ohnishi M, Oda Y, (2006) Presence of glucosylceramide in yeast and its relation to alkali tolerance of yeast. Appl Microbiol Biotechnol 71: 515-521.
42. Zou X, Gao Y, Ruvolo VR, Gardner TL, Ruvolo PP, et al. (2010) Human glycolipid transfer protein gene (GLTP) expression is regulated by Sp1 and Sp3: Involvement of the bioactive sphingolipid ceramide. J Biol Chem In press.
43. Halter D, Neumann S, van Dijk SM, Wolthoorn J, de Maziere AM, et al. (2007) Pre- and post-Golgi translocation of glucosylceramide in glycosphingolipid synthesis. J Cell Biol 179: 101-115.
44. Kawano M, Kumagai K, Nishijima M, Hanada K, (2006) Efficient trafficking of ceramide from the endoplasmic reticulum to the Golgi apparatus requires a VAMP-associated protein-interacting FFAT motif of CERT. J Biol Chem 281: 30279-30288.
45. Kaiser SE, Brickner JH, Reilein AR, Fenn TD, Walter P, et al. (2005) Structural basis of FFAT motif-mediated ER targeting. Structure 13: 1035-1045.
46. Hanada K, (2010) Intracellular trafficking of ceramide by ceramide transfer protein. Proc Jpn Acad Ser B Phys Biol Sci 86: 426-437.
47. Sasaki T, (1990) Glycolipid transfer protein and intracellular traffic of glucosylceramide. Experientia 46: 611-616.
48. Warnock DE, Lutz MS, Blackburn WA, Young WW, Baenziger JU, (1994) Transport of newly synthesized glucosylceramide to the plasma membrane by a non-Golgi pathway. Proc Natl Acad Sci U S A 91: 2708-2712.
49. De Matteis MA, Luna A, Di Tullio G, Corda D, Kok JW, et al. (1999) PDMP blocks the BFA-induced ADP-ribosylation of BARS-50 in isolated Golgi membranes. FEBS Lett 459: 310-312.
50. Kok JW, Babia T, Filipeanu CM, Nelemans A, Egea G, et al. (1998) PDMP blocks brefeldin A-induced retrograde membrane transport from golgi to ER: evidence for involvement of calcium homeostasis and dissociation from sphingolipid metabolism. J Cell Biol 142: 25-38.
51. Hait NC, Oskeritzian CA, Paugh SW, Milstien S, Spiegel S, (2006) Sphingosine kinases, sphingosine 1-phosphate, apoptosis and diseases. Biochim Biophys Acta 1758: 2016-2026.
52. van Meer G, Lisman Q, (2002) Sphingolipid transport; rafts and translocators. J Biol Chem 277: 25855-25858.