Impact of weight loss with or without exercise on abdominal fat and insulin resistance in obese individuals: A randomised clinical trial

British Journal of Nutrition

Volumn 110, Issue 3, 2013, Pages 486-492

  Fayh, Ana Paula Trussardi ^a,b   Lopes, André Luiz ^c   Fernandes, Pablo Rober ^c   Reischak Oliveira, Alvaro ^c   Friedman, Rogério ^a  

^a HOSPITAL DE CLÍNICAS DE PORTO ALEGRE   (Brazil)

^b FEDERAL UNIVERSITY OF RIO GRANDE DO NORTE   (Brazil)

^c FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

Author keywords

Diet; Insulin resistance; Obese; Physical training; Weight loss

Indexed keywords

C REACTIVE PROTEIN; GLUCOSE; INSULIN;

ABDOMINAL OBESITY; ADIPOSE TISSUE; ADULT; AEROBIC EXERCISE; ARTICLE; BODY MASS; CLINICAL ARTICLE; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; DIET THERAPY; FEMALE; GLUCOSE BLOOD LEVEL; HUMAN; INSULIN RESISTANCE; INTRAABDOMINAL FAT; MAINTENANCE THERAPY; MALE; OUTCOME ASSESSMENT; RANDOMIZED CONTROLLED TRIAL; SUBCUTANEOUS FAT; THERAPY EFFECT; WEIGHT REDUCTION;

ABDOMINAL FAT; ADULT; BLOOD GLUCOSE; C-REACTIVE PROTEIN; CARDIOVASCULAR DISEASES; DIET, REDUCING; EXERCISE; FEMALE; HUMANS; INFLAMMATION; INSULIN; INSULIN RESISTANCE; MALE; OBESITY; OBESITY, ABDOMINAL; WEIGHT LOSS;

EID: 84880842389     PISSN: 00071145     EISSN: 14752662     Source Type: Journal    
DOI: 10.1017/S0007114512005442     Document Type: Article

References (37)

1. Lemieux I, Poirier P, Bergeron J, et al. (2007) Hypertriglyceridemic waist: a useful screening phenotype in preventive cardiology? Can J Cardiol 23, 23B-31B.
2. Rexrode KM, Carey VJ, Hennekens CH, et al. (1998) Abdominal adiposity and coronary heart disease in women. JAMA 280, 1843-1848.
3. Yusuf S, Hawken S, Ounpuu S, et al. (2005) Obesity and the risk of myocardial infarction in 27,000 participants from 52 countries: a case-control study. Lancet 366, 1640-1649.
4. Kuk JL, Katzmarzyk PT, Nichaman MZ, et al. (2006) Visceral fat is an independent predictor of all-cause mortality in men. Obes Res 14, 336-341.
5. Klein S, Allison DB, Heymsfield SB, et al. (2007) Waist circumference and cardiometabolic risk: a consensus statement from shaping America's health: Association for Weight Management and Obesity Prevention; NAASO, the Obesity Society; the American Society for Nutrition; and the American Diabetes Association. Diabetes Care 30, 1647-1652.
6. Kim K, Valentine RJ, Shin Y, et al. (2008) Associations of visceral adiposity and exercise participation with C-reactive protein, insulin resistance, and endothelial dysfunction in Korean healthy adults. Metabol Clin Exp 57, 1181-1189.
7. Snijder MB, Visser M, Dekker JM, et al. (2002) The prediction of visceral fat by dual-energy X-ray absorptiometry in the elderly: a comparison with computed tomography and anthropometry. Int J Obes 26, 984-993.
8. Bougoulia M, Triantos A & Koliakos G (2006) Plasma interleukin-6 levels, glutathione peroxidase and isoprostane in obese women before and after weight loss. Association with cardiovascular risk factors. Hormones 5, 192-199.
9. Weinstock RS, Dai H & Wadden TA (1998) Diet and exercise in the treatment of obesity: effects of 3 interventions on insulin resistance. Arch Intern Med 158, 2477-2483.
10. Xydakis AM, Case CC, Jones PH, et al. (2004) Adiponectin, inflammation, and the expression of the metabolic syndrome in obese individuals: the impact of rapid weight loss through caloric restriction. J Clin Endocrinol Metab 89, 2697-2703.
11. Geffken DF, Cushman M, Burke GL, et al. (2001) Association between physical activity and markers of inflammation in a health elderly population. Am J Epidemiol 153, 242-250.
12. Aronson D, Sella R, Sheikh-Ahmad M, et al. (2004) The association between cardiorespiratory fitness and C-reactive protein in subjects with the metabolic syndrome. J Am Coll Cardiol 44, 2003-2007.
13. Oberbach A, Tonjes A, Kloting N, et al. (2006) Effect of a 4 week physical training program on plasma concentrations of inflammatory markers in patients with abnormal glucose tolerance. Eur J Endocrinol 154, 577-585.
14. Sposito AC, Caramelli B, Fonseca FAH, et al. (2007) IV Diretriz Brasileira sobre Dislipidemias e Prevenção da Aterosclerose: Departamento de Aterosclerose da Sociedade Brasileira de Cardiologia (IV Brazilian guidelines on dyslipidemia and atherosclerosis prevention: Department of Atherosclerosis of Brazilian Society of Cardiology). Arq Bras Cardiol 88, 2-19.
15. Karvonen JJ, Kentala E & Mustala O (1957) The effects of training on heart rate: a "longitudinal" study. Ann Med Exp Biol Fenn 35, 307-315.
16. McGuire DK, Levine BD, Williamson JW, et al. (2001) A 30-year follow-up of the Dallas Bed Rest and Training Study: I. Effect of age on the cardiovascular response to exercise. Circulation 104, 1350-1357.
17. Organização Mundial da Saúde/Organização Pan-Americana da Saúde (2003) Doenças crônico-degenerativas e Obesidade: estratégia mundial sobre alimentação saudável, atividade física e saúde (Chronic diseases and obesity: global strategy on diet, physical activity and health). http://www. opas.org.br/sistema/arquivos/d-cronic.pdf (accessed May 2009).
18. Seidell JC, Oosterlee A, Thijssen MA, et al. (1987) Assessment of intra-abdominal and subcutaneous abdominal fat: relation between anthropometry and computed tomography. Am J Clin Nutr 45, 7-13.
19. Matthews DR, Hosker JP, Rudenski AS, et al. (1985) Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28, 412-419.
20. Nicklas BJ, Ambrosius W, Messier SP, et al. (2004) Dietinduced weight loss, exercise, and chronic inflammation in older, obese adults: a randomized controlled clinical trial. Am J Clin Nutr 79, 544-551.
21. Weiss EP, Racette SB, Villareal DT, et al. (2006) Improvements in glucose tolerance and insulin action induced by increasing energy expenditure or decreasing energy intake: a randomized controlled trial. Am J Clin Nutr 84, 1033-1042.
22. Hotta K, Funahashi T, Arita Y, et al. (2000) Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients. Arterioscler Thromb Vasc Biol 20, 1595-1599.
23. Fox CS, Massaro JM, Hoffmann U, et al. (2007) Abdominal visceral and subcutaneous adipose tissue compartments: association with metabolic risk factors in the Framingham Heart Study. Circulation 116, 39-48.
24. Saijo Y, Kiyota N, Kawasaki Y, et al. (2004) Relationship between C-reactive protein and visceral adipose tissue in healthy Japanese subjects. Diabetes Obes Metab 6, 249-258.
25. Kullberg J, Below CV, Lönn L, et al. (2007) Practical approach for estimation of subcutaneous and visceral adipose tissue. Clin Physiol Funct Imaging 27, 148-153.
26. Marques MD, Santos RD, Parga JR, et al. (2010) Relation between visceral fat and coronary artery disease evaluated by multidetector computed tomography. Atherosclerosis 209, 481-486.
27. Weyer C, Bogardus C, Mott DM, et al. (1999) The natural history of insulin secretory dysfunction and insulin resistance in the pathogenesis of type 2 diabetes mellitus. J Clin Invest 104, 787-794.
28. Tanasescu M, Leitzmann MF, Rimm EB, et al. (2003) Physical activity in relation to cardiovascular disease and total mortality among men with type 2 diabetes. Circulation 107, 2435-2439.
29. Stewart KJ (2004) Exercise training: can it improve cardiovascular health in patients with type 2 diabetes? Br J Sports Med 38, 250-252.
30. Fisher G, Hyatt TC, Hunter GR, et al. (2011) Effect of diet with and without exercise training on markers of inflammation and fat distribution in overweight women. Obesity (Silver Spring) 19, 1131-1136.
31. Sureda A, Tauler P, Aguilo A, et al. (2005) Relation between oxidative stress markers and antioxidant endogenous differences during exhaustive exercise. Free Radic Res 39, 1317-1324.
32. Cooper CE, Vollaard NB, Choueiri T, et al. (2001) Exercise, free radicals and oxidative stress. Biochem Soc Trans 30, 280-284.
33. Festa A, D'Agostino How Jr R, Ard G, et al. (2000) Chronic subclinical inflammation as part of the insulin resistance syndrome: the Insulin Resistance Atherosclerosis Study (IRAS). Circulation 102, 42-47.
34. Rutter MK, Meigs JB, Sullivan LM, et al. (2004) C-Reactive protein, the metabolic syndrome, and prediction of cardiovascular events in the Framingham Offspring Study. Circulation 110, 380-385.
35. Karelis AD, Faraj M, Bastard JP, et al. (2005) The metabolically healthy but obese individual presents a favorable inflammation profile. J Clin Endocrinol Metab 90, 4145-4150.
36. Garber CE, Blissmer B, Deschenes MR, et al. (2011) American College of Sports Medicine position stand. Quantity and quality of exercise for developing and maintaining cardiorespiratory, musculoskeletal, and neuromotor fitness in apparently healthy adults: guidance for prescribing exercise. Med Sci Sports Exerc 43, 1334-1359.
37. Fletcher GF, Balady GJ, Amsterdam EA, et al. (2001) Exercise standards for testing and training: a statement for healthcare professionals from the American Heart Association. Circulation 104, 1694-1740. Ciência e Tecnologia Tecnológico and FIPE-Hospital de Clínicas de Porto Alegre