NOTCH1 Gain of Function in Germ Cells Causes Failure of Spermatogenesis in Male Mice

PLoS ONE

Volumn 8, Issue 7, 2013, Pages

  Huang, Zaohua ^a   Rivas, Bryan ^a   Agoulnik, Alexander I ^a,b  

^a FLORIDA INTERNATIONAL UNIVERSITY   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NEUROGENIN 3; NOTCH1 RECEPTOR; PROTEIN P53; PROTEIN P63; TRANSCRIPTION FACTOR HES 5;

AGE; ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; CELL SURVIVAL; CONTROLLED STUDY; GAIN OF FUNCTION MUTATION; GENE; GENE DELETION; GENE EXPRESSION REGULATION; GENE TARGETING; HES5 GENE; IMMUNOHISTOCHEMISTRY; INTRACELLULAR SIGNALING; MALE; MOUSE; NEUROG3 GENE; NONHUMAN; NOTCH1 GENE; PROTEIN EXPRESSION; SPERMATOGENESIS; SPERMATOGONIUM; SPERMATOZOON ABNORMALITY; SPERMATOZOON COUNT; TESTIS WEIGHT; TRANSGENE; TRP53 GENE; TRP63 GENE;

ANIMALS; APOPTOSIS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; FERTILITY; GENE DELETION; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE ORDER; GENETIC VECTORS; GERM CELLS; MALE; MICE; MUTATION; NERVE TISSUE PROTEINS; RECEPTOR, NOTCH1; SIGNAL TRANSDUCTION; SPERMATOGENESIS; TESTIS;

EID: 84880832296     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0071213     Document Type: Article

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