메뉴 건너뛰기




Volumn 59, Issue , 2013, Pages 344-353

Phthalate metabolites in obese individuals undergoing weight loss: Urinary levels and estimation of the phthalates daily intake

Author keywords

Intake estimation; Obesity; Phthalate metabolites; Phthalates; Urine; Weight loss

Indexed keywords

AIR INTAKES; BIOMOLECULES; BODY FLUIDS; ESTERS; FOOD SUPPLY; METABOLITES; NUTRITION; REGRESSION ANALYSIS;

EID: 84880828308     PISSN: 01604120     EISSN: 18736750     Source Type: Journal    
DOI: 10.1016/j.envint.2013.06.023     Document Type: Article
Times cited : (70)

References (56)
  • 2
    • 0020470927 scopus 로고
    • Chromatographic-separation and quantitative-determination of the metabolites of di-(2-ethylhexyl) phthalate from urine of laboratory-animals
    • Albro P.W., Jordan S.T., Schroeder J.L., Corbett J.T. Chromatographic-separation and quantitative-determination of the metabolites of di-(2-ethylhexyl) phthalate from urine of laboratory-animals. J Chromatogr A 1982, 224:65-79.
    • (1982) J Chromatogr A , vol.224 , pp. 65-79
    • Albro, P.W.1    Jordan, S.T.2    Schroeder, J.L.3    Corbett, J.T.4
  • 3
    • 0035196987 scopus 로고    scopus 로고
    • A biomarker approach to measuring human dietary exposure to certain phthalate diesters
    • Anderson W.A., Castle L., Scotter M.J., Massey R.C., Springall C. A biomarker approach to measuring human dietary exposure to certain phthalate diesters. Food Addit Contam 2001, 18:1068-1074.
    • (2001) Food Addit Contam , vol.18 , pp. 1068-1074
    • Anderson, W.A.1    Castle, L.2    Scotter, M.J.3    Massey, R.C.4    Springall, C.5
  • 4
    • 0035084122 scopus 로고    scopus 로고
    • Toxicological profile of diethyl phthalate: a vehicle for fragrance and cosmetic ingredients
    • Api A.M. Toxicological profile of diethyl phthalate: a vehicle for fragrance and cosmetic ingredients. Food Chem Toxicol 2001, 39:97-108.
    • (2001) Food Chem Toxicol , vol.39 , pp. 97-108
    • Api, A.M.1
  • 5
    • 0005595638 scopus 로고
    • U.S. Department of Health and Human Service, Division of Toxicology/Toxicology Information Branch, Atlanta, Georgia, ATSDR (Agency for Toxic Substances and Disease Registry)
    • ATSDR (Agency for Toxic Substances and Disease Registry) Toxicological profile for diethyl phthalate 1995, U.S. Department of Health and Human Service, Division of Toxicology/Toxicology Information Branch, Atlanta, Georgia.
    • (1995) Toxicological profile for diethyl phthalate
  • 6
    • 0042305705 scopus 로고    scopus 로고
    • U.S. Department of Health and Human Service, Division of Toxicology/Toxicology Information Branch, Atlanta, Georgia, ATSDR (Agency for Toxic Substances and Disease Registry)
    • ATSDR (Agency for Toxic Substances and Disease Registry) Toxicological profile for di-n-butyl phthalate 2001, U.S. Department of Health and Human Service, Division of Toxicology/Toxicology Information Branch, Atlanta, Georgia.
    • (2001) Toxicological profile for di-n-butyl phthalate
  • 7
    • 0041304143 scopus 로고    scopus 로고
    • U.S. Department of Health and Human Service, Division of Toxicology/Toxicology Information Branch, Atlanta, Georgia, ATSDR (Agency for Toxic Substances and Disease Registry)
    • ATSDR (Agency for Toxic Substances and Disease Registry) Toxicological profile for di-(2-ethylhexyl) phthalate 2002, U.S. Department of Health and Human Service, Division of Toxicology/Toxicology Information Branch, Atlanta, Georgia.
    • (2002) Toxicological profile for di-(2-ethylhexyl) phthalate
  • 9
    • 77956803336 scopus 로고    scopus 로고
    • Simultaneous selective detection of organophosphate and phthalate esters using gas chromatography with positive ion chemical ionization tandem mass spectrometry and its application to indoor air and dust
    • Bergh C., Torgrip R., Östman C. Simultaneous selective detection of organophosphate and phthalate esters using gas chromatography with positive ion chemical ionization tandem mass spectrometry and its application to indoor air and dust. Rapid Commun Mass Spectrom 2010, 24:2859-2867.
    • (2010) Rapid Commun Mass Spectrom , vol.24 , pp. 2859-2867
    • Bergh, C.1    Torgrip, R.2    Östman, C.3
  • 16
    • 33749661607 scopus 로고    scopus 로고
    • Opinion of the scientific panel in food additives, flavourings, processing aids and materials in contact with food (AFC) on a request from the Commission related to: Bis(2-ethylhexyl)phthalate (DEHP) for use in food contact materials. Question no EFSA-Q-2003-191
    • EFSA (European Food Safety Authority)
    • EFSA (European Food Safety Authority) Opinion of the scientific panel in food additives, flavourings, processing aids and materials in contact with food (AFC) on a request from the Commission related to: Bis(2-ethylhexyl)phthalate (DEHP) for use in food contact materials. Question no EFSA-Q-2003-191. EFSA J 2005, 243:1-20.
    • (2005) EFSA J , vol.243 , pp. 1-20
  • 17
    • 33749661607 scopus 로고    scopus 로고
    • Opinion of the scientific panel in food additives, flavourings, processing aids and materials in contact with food (AFC) on a request from the Commission related to: butylbenzylphthalate (BBP) for use in food contact materials. Question no EFSA-Q-2003-190
    • EFSA (European Food Safety Authority)
    • EFSA (European Food Safety Authority) Opinion of the scientific panel in food additives, flavourings, processing aids and materials in contact with food (AFC) on a request from the Commission related to: butylbenzylphthalate (BBP) for use in food contact materials. Question no EFSA-Q-2003-190. EFSA J 2005, 241:1-14.
    • (2005) EFSA J , vol.241 , pp. 1-14
  • 18
    • 33749661607 scopus 로고    scopus 로고
    • Opinion of the scientific panel in food additives, flavourings, processing aids and materials in contact with food (AFC) on a request from the Commission related to: di-butylphthalate (DBP) for use in food contact materials. Question no EFSA-Q-2003-192
    • EFSA (European Food Safety Authority)
    • EFSA (European Food Safety Authority) Opinion of the scientific panel in food additives, flavourings, processing aids and materials in contact with food (AFC) on a request from the Commission related to: di-butylphthalate (DBP) for use in food contact materials. Question no EFSA-Q-2003-192. EFSA J 2005, 242:1-18.
    • (2005) EFSA J , vol.242 , pp. 1-18
  • 19
    • 33749661607 scopus 로고    scopus 로고
    • Opinion of the scientific panel in food additives, flavourings, processing aids and materials in contact with food (AFC) on a request from the Commission related to: di-isononylphthalate (DINP) for use in food contact materials. Question no EFSA-Q-2003-1942
    • EFSA (European Food Safety Authority)
    • EFSA (European Food Safety Authority) Opinion of the scientific panel in food additives, flavourings, processing aids and materials in contact with food (AFC) on a request from the Commission related to: di-isononylphthalate (DINP) for use in food contact materials. Question no EFSA-Q-2003-1942. EFSA J 2005, 244:1-18.
    • (2005) EFSA J , vol.244 , pp. 1-18
  • 20
    • 79958277841 scopus 로고    scopus 로고
    • Urinary excretion of phthalate metabolites in 129 healthy Danish children and adolescents: estimation of daily phthalate intake
    • Frederiksen H., Aksglaede L., Sorensen K., Skakkebaek N.E., Juul A., Andersson A.-M. Urinary excretion of phthalate metabolites in 129 healthy Danish children and adolescents: estimation of daily phthalate intake. Environ Res 2011, 111:656-663.
    • (2011) Environ Res , vol.111 , pp. 656-663
    • Frederiksen, H.1    Aksglaede, L.2    Sorensen, K.3    Skakkebaek, N.E.4    Juul, A.5    Andersson, A.-M.6
  • 22
    • 33750482232 scopus 로고    scopus 로고
    • Altered semen quality in relation to urinary concentrations of phthalate monoester and oxidative metabolites
    • Hauser R., Meeker J.D., Duty S., Silva M.J., Calafat A.M. Altered semen quality in relation to urinary concentrations of phthalate monoester and oxidative metabolites. Epidemiology 2006, 17:682-691.
    • (2006) Epidemiology , vol.17 , pp. 682-691
    • Hauser, R.1    Meeker, J.D.2    Duty, S.3    Silva, M.J.4    Calafat, A.M.5
  • 23
    • 60749127831 scopus 로고    scopus 로고
    • Concentrations of phthalate metabolites in milk, urine, saliva, and serum of lactating North Carolina women
    • Hines E.P., Calafat A.M., Silva M.J., Mendola P., Fenton S.E. Concentrations of phthalate metabolites in milk, urine, saliva, and serum of lactating North Carolina women. Environ Health Perspect 2009, 117:86-92.
    • (2009) Environ Health Perspect , vol.117 , pp. 86-92
    • Hines, E.P.1    Calafat, A.M.2    Silva, M.J.3    Mendola, P.4    Fenton, S.E.5
  • 25
    • 34447266656 scopus 로고    scopus 로고
    • Quantitative identification of unknown exposure pathways of phthalates based on measuring their metabolites in human urine
    • Itoh H., Yoshida K., Masunaga S. Quantitative identification of unknown exposure pathways of phthalates based on measuring their metabolites in human urine. Environ Sci Technol 2007, 41:4542-4547.
    • (2007) Environ Sci Technol , vol.41 , pp. 4542-4547
    • Itoh, H.1    Yoshida, K.2    Masunaga, S.3
  • 26
    • 84930479869 scopus 로고    scopus 로고
    • Urinary phthalate metabolite concentrations and diabetes among women in the National Health and Nutrition Examination Survey (NHANES) 2001-2008
    • James-Todd T., Stahlhut R., Meeker J.D., Powell S.G., Hauser R., Huang T.Y., Rich-Edwards J. Urinary phthalate metabolite concentrations and diabetes among women in the National Health and Nutrition Examination Survey (NHANES) 2001-2008. Environ Health Perspect 2012, 120:1307-1313.
    • (2012) Environ Health Perspect , vol.120 , pp. 1307-1313
    • James-Todd, T.1    Stahlhut, R.2    Meeker, J.D.3    Powell, S.G.4    Hauser, R.5    Huang, T.Y.6    Rich-Edwards, J.7
  • 27
    • 67650803296 scopus 로고    scopus 로고
    • Human body burdens of chemicals used in plastic manufacture
    • Koch H.M., Calafat A.M. Human body burdens of chemicals used in plastic manufacture. Philos Trans R Soc Lond B Biol Sci 2009, 364:2063-2078.
    • (2009) Philos Trans R Soc Lond B Biol Sci , vol.364 , pp. 2063-2078
    • Koch, H.M.1    Calafat, A.M.2
  • 28
    • 22844433529 scopus 로고    scopus 로고
    • New metabolites of di(2-ethylhexyl)phthalate (DEHP) in human urine and serum after single oral doses of deuterium-labelled DEHP
    • Koch H.M., Bolt H.M., Preuss R., Angerer J. New metabolites of di(2-ethylhexyl)phthalate (DEHP) in human urine and serum after single oral doses of deuterium-labelled DEHP. Arch Toxicol 2005, 79:367-376.
    • (2005) Arch Toxicol , vol.79 , pp. 367-376
    • Koch, H.M.1    Bolt, H.M.2    Preuss, R.3    Angerer, J.4
  • 29
    • 34447509273 scopus 로고    scopus 로고
    • Di-n-butylphthalate and butylbenzylphthalate-urinary metabolite levels and estimated daily intakes: Pilot study for the German Environmental Survey on children
    • Koch H.M., Becker K., Wittassek M., Seiwert M., Angerer J., Kolossa-Gehring M. Di-n-butylphthalate and butylbenzylphthalate-urinary metabolite levels and estimated daily intakes: Pilot study for the German Environmental Survey on children. J Expo Sci Environ Epidemiol 2007, 17:378-387.
    • (2007) J Expo Sci Environ Epidemiol , vol.17 , pp. 378-387
    • Koch, H.M.1    Becker, K.2    Wittassek, M.3    Seiwert, M.4    Angerer, J.5    Kolossa-Gehring, M.6
  • 30
    • 79958032364 scopus 로고    scopus 로고
    • Exposure to phthalates in 5-6years old primary school starters in Germany-a human biomonitoring study and a cumulative risk assessment
    • Koch H.M., Wittassek M., Brüning T., Angerer J., Heudorf U. Exposure to phthalates in 5-6years old primary school starters in Germany-a human biomonitoring study and a cumulative risk assessment. Int J Hyg Environ Health 2011, 214:188-195.
    • (2011) Int J Hyg Environ Health , vol.214 , pp. 188-195
    • Koch, H.M.1    Wittassek, M.2    Brüning, T.3    Angerer, J.4    Heudorf, U.5
  • 31
    • 69249137916 scopus 로고    scopus 로고
    • Recent European Food Safety Authority toxicological evaluations of major phthalates used in food contact materials
    • Lhuguenot J.C. Recent European Food Safety Authority toxicological evaluations of major phthalates used in food contact materials. Mol Nutr Food Res 2009, 53:1063-1070.
    • (2009) Mol Nutr Food Res , vol.53 , pp. 1063-1070
    • Lhuguenot, J.C.1
  • 33
    • 84867616124 scopus 로고    scopus 로고
    • Serum concentrations of phthalate metabolites are related to abdominal fat distribution two years later in elderly women
    • Lind P.M., Roos V., Rönn M., Johansson L., Ahlström H., Kullberg J., Lind L. Serum concentrations of phthalate metabolites are related to abdominal fat distribution two years later in elderly women. Environ Health 2012, 11:1-8.
    • (2012) Environ Health , vol.11 , pp. 1-8
    • Lind, P.M.1    Roos, V.2    Rönn, M.3    Johansson, L.4    Ahlström, H.5    Kullberg, J.6    Lind, L.7
  • 34
    • 84862884577 scopus 로고    scopus 로고
    • Circulating levels of phthalate metabolites are associated with prevalent diabetes in the elderly
    • Lind P.M., Zethelius B., Lind L. Circulating levels of phthalate metabolites are associated with prevalent diabetes in the elderly. Diabetes Care 2012, 35:1519-1524.
    • (2012) Diabetes Care , vol.35 , pp. 1519-1524
    • Lind, P.M.1    Zethelius, B.2    Lind, L.3
  • 35
    • 80054827544 scopus 로고    scopus 로고
    • A critical evaluation of the creatinine correction approach: can it underestimate intakes of phthalates? A case study with di-2-ethylhexyl phthalate
    • Lorber M., Koch H.M., Angerer J. A critical evaluation of the creatinine correction approach: can it underestimate intakes of phthalates? A case study with di-2-ethylhexyl phthalate. J Expo Sci Environ Epidemiol 2011, 21:576-586.
    • (2011) J Expo Sci Environ Epidemiol , vol.21 , pp. 576-586
    • Lorber, M.1    Koch, H.M.2    Angerer, J.3
  • 37
    • 80053452007 scopus 로고    scopus 로고
    • Relationship between urinary phthalate and bisphenol A concentrations and serum thyroid measures in U.S. adults and adolescents from the National Health and Nutrition Examination Survey (NHANES) 2007-2008
    • Meeker J.D., Ferguson K.K. Relationship between urinary phthalate and bisphenol A concentrations and serum thyroid measures in U.S. adults and adolescents from the National Health and Nutrition Examination Survey (NHANES) 2007-2008. Environ Health Perspect 2011, 119:1396-1402.
    • (2011) Environ Health Perspect , vol.119 , pp. 1396-1402
    • Meeker, J.D.1    Ferguson, K.K.2
  • 38
    • 67650813037 scopus 로고    scopus 로고
    • Phthalates and other additives in plastics: human exposure and associated health outcomes
    • Meeker J.D., Sathyanarayana S., Swan S.H. Phthalates and other additives in plastics: human exposure and associated health outcomes. Philos Trans R Soc Lond B 2009, 364:2097-2113.
    • (2009) Philos Trans R Soc Lond B , vol.364 , pp. 2097-2113
    • Meeker, J.D.1    Sathyanarayana, S.2    Swan, S.H.3
  • 40
    • 75249087492 scopus 로고    scopus 로고
    • Exposure to chemicals via house dust
    • National Institute for Public Health and Environment, [Available from: (accessed April 2013)]
    • Oomen A.G., Janssen P.J.C.M., Dusseldorp A., Noorlander C.W. Exposure to chemicals via house dust. RIVM Report 609021064/2008 2008, National Institute for Public Health and Environment, [Available from: http://www.rivm.nl/dsresource?objectid=rivmp:16687&type=org&disposition=inline&ns_nc=1(accessed April 2013)].
    • (2008) RIVM Report 609021064/2008
    • Oomen, A.G.1    Janssen, P.J.C.M.2    Dusseldorp, A.3    Noorlander, C.W.4
  • 42
    • 56449103597 scopus 로고    scopus 로고
    • Endocrine disrupting chemicals in indoor and outdoor air
    • Rudel R.A., Perovich L.J. Endocrine disrupting chemicals in indoor and outdoor air. Atmos Environ 2009, 43:170-181.
    • (2009) Atmos Environ , vol.43 , pp. 170-181
    • Rudel, R.A.1    Perovich, L.J.2
  • 43
    • 38349185521 scopus 로고    scopus 로고
    • Phthalates and children's health. Curr. Probl. Pediatr. Adolesc
    • Sathyanarayana S. Phthalates and children's health. Curr. Probl. Pediatr. Adolesc. Health Care 2008, 38:34-49.
    • (2008) Health Care , vol.38 , pp. 34-49
    • Sathyanarayana, S.1
  • 46
    • 38449107525 scopus 로고    scopus 로고
    • PPAR agonists and the metabolic syndrome
    • Staels B. PPAR agonists and the metabolic syndrome. Therapie 2007, 62:319-326.
    • (2007) Therapie , vol.62 , pp. 319-326
    • Staels, B.1
  • 47
    • 34250184495 scopus 로고    scopus 로고
    • Concentrations of urinary phthalate metabolites are associated with increased waist circumference and insulin resistance in adult U.S. males
    • Stahlhut R.W., van W.E., Dye T.D., Cook S., Swan S.H. Concentrations of urinary phthalate metabolites are associated with increased waist circumference and insulin resistance in adult U.S. males. Environ Health Perspect 2007, 115:876-882.
    • (2007) Environ Health Perspect , vol.115 , pp. 876-882
    • Stahlhut, R.W.1    van, W.E.2    Dye, T.D.3    Cook, S.4    Swan, S.H.5
  • 48
    • 84877829215 scopus 로고    scopus 로고
    • Urinary metabolite concentrations of phthalate metabolites in Central Italy healthy volunteers determined by a validated HPLC/MS/MS analytical method
    • Tranfo G., Papaleo B., Caporossi L., Capanna S., De Rosa M., Pigini D., Corsetti F., Paci E. Urinary metabolite concentrations of phthalate metabolites in Central Italy healthy volunteers determined by a validated HPLC/MS/MS analytical method. Int J Hyg Environ Health 2013, 216:481-485.
    • (2013) Int J Hyg Environ Health , vol.216 , pp. 481-485
    • Tranfo, G.1    Papaleo, B.2    Caporossi, L.3    Capanna, S.4    De Rosa, M.5    Pigini, D.6    Corsetti, F.7    Paci, E.8
  • 49
    • 84875911959 scopus 로고    scopus 로고
    • Race/ethnicity specific associations of urinary phthalates with childhood body mass in a nationally representative sample
    • Trasande L., Attina T.M., Sathyanarayana S., Spanier A.J., Blustein J. Race/ethnicity specific associations of urinary phthalates with childhood body mass in a nationally representative sample. Environ Health Perspect 2013, 121:501-506.
    • (2013) Environ Health Perspect , vol.121 , pp. 501-506
    • Trasande, L.1    Attina, T.M.2    Sathyanarayana, S.3    Spanier, A.J.4    Blustein, J.5
  • 50
    • 0036664149 scopus 로고    scopus 로고
    • Relationship between age and levels of organochlorine contaminants in human serum of a Belgian population
    • Voorspoels S., Covaci A., Maervoet J., Schepens P. Relationship between age and levels of organochlorine contaminants in human serum of a Belgian population. Bull Environ Contam Toxicol 2002, 69:22-29.
    • (2002) Bull Environ Contam Toxicol , vol.69 , pp. 22-29
    • Voorspoels, S.1    Covaci, A.2    Maervoet, J.3    Schepens, P.4
  • 51
    • 84874240379 scopus 로고    scopus 로고
    • Urinary phthalate metabolites are associated with body mass index and waist circumference in Chinese school children
    • Wang H., Zhou Y., Tang C., He Y., Wu J., Chen Y., Jiang Q. Urinary phthalate metabolites are associated with body mass index and waist circumference in Chinese school children. PLoS One 2013, 8:e56800.
    • (2013) PLoS One , vol.8
    • Wang, H.1    Zhou, Y.2    Tang, C.3    He, Y.4    Wu, J.5    Chen, Y.6    Jiang, Q.7
  • 52
    • 33846251887 scopus 로고    scopus 로고
    • Daily intake of di(2-ethylhexyl)phthalate (DEHP) by German children-A comparison of two estimation models based on urinary DEHP metabolite levels
    • Wittassek M., Heger W., Koch H.M., Becker K., Angerer J., Kolossa-Gehring M. Daily intake of di(2-ethylhexyl)phthalate (DEHP) by German children-A comparison of two estimation models based on urinary DEHP metabolite levels. Int J Hyg Environ Health 2007, 210:35-42.
    • (2007) Int J Hyg Environ Health , vol.210 , pp. 35-42
    • Wittassek, M.1    Heger, W.2    Koch, H.M.3    Becker, K.4    Angerer, J.5    Kolossa-Gehring, M.6
  • 54
    • 80052546945 scopus 로고    scopus 로고
    • Comparison of 24-h volume and creatinine-corrected total urinary polyphenol as a biomarker of total dietary polyphenols in the Invecchiare InCHIANTI study
    • Zamora-Ros R., Rabassa M., Cherubini A., Urpi-Sarda M., Llorach R., Bandinelli S., Ferrucci L., Andres-Lacueva C. Comparison of 24-h volume and creatinine-corrected total urinary polyphenol as a biomarker of total dietary polyphenols in the Invecchiare InCHIANTI study. Anal Chim Acta 2011, 704:110-115.
    • (2011) Anal Chim Acta , vol.704 , pp. 110-115
    • Zamora-Ros, R.1    Rabassa, M.2    Cherubini, A.3    Urpi-Sarda, M.4    Llorach, R.5    Bandinelli, S.6    Ferrucci, L.7    Andres-Lacueva, C.8
  • 55
    • 84875273617 scopus 로고    scopus 로고
    • Approach to distribution and accumulation of dibutyl phthalate in rats by immunoassay
    • Zeng Q., Wei C., Wu Y., Li K., Ding S., Yuan J., Yang X., Chen M. Approach to distribution and accumulation of dibutyl phthalate in rats by immunoassay. Food Chem Toxicol 2013, 56:18-27.
    • (2013) Food Chem Toxicol , vol.56 , pp. 18-27
    • Zeng, Q.1    Wei, C.2    Wu, Y.3    Li, K.4    Ding, S.5    Yuan, J.6    Yang, X.7    Chen, M.8
  • 56
    • 35348996982 scopus 로고    scopus 로고
    • Environmental chemicals impacting the thyroid: targets and consequences
    • Zoeller R.T. Environmental chemicals impacting the thyroid: targets and consequences. Thyroid 2007, 17:811-817.
    • (2007) Thyroid , vol.17 , pp. 811-817
    • Zoeller, R.T.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.