Dysbiosis, a new medical concept;La dysbiose, une nouvelle entité en médecine ?

Medecine/Sciences

Volumn 29, Issue 6-7, 2013, Pages 586-589

  Normand, Sylvain ^a,b,c,d   Secher, Thomas ^e   Chamaillard, Mathias ^a,b,c,d  

^a UNIV LILLE   (France)

^b INSTITUT PASTEUR DE LILLE   (France)

^c CNRS   (France)

^d INSERM   (France)

^e CEMAGREF   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE RECRUITMENT DOMAIN PROTEIN 15; NOD2 PROTEIN, HUMAN;

ARTICLE; CROHN DISEASE; HUMAN; IMMUNITY; METAGENOME; PHYSIOLOGY;

CROHN DISEASE; HUMANS; IMMUNITY; METAGENOME; NOD2 SIGNALING ADAPTOR PROTEIN;

EID: 84880778102     PISSN: 07670974     EISSN: 19585381     Source Type: Journal    
DOI: 10.1051/medsci/2013296011     Document Type: Article

References (26)

1. Arumugam M, Raes J, Pelletier E, et al. Enterot ypes of the human gut microbiome. Nature 2011; 473 : 174-80.
2. Yatsunenko T, Rey FE, Manary MJ, et al. Human g ut microbiome viewed across age and geography. Nature 2012; 486 : 222-7.
3. Wu GD, Chen J, Hoffmann C, et al. Linking long- term dietary patterns with gut microbial enterotypes. Science 2011; 334 : 105-8.
4. Muegge BD, Kuczynski J, Knights D, et al. Diet drives convergence in gut microbiome functions across mammalian phylogeny and within humans. Science 2011; 332 : 970-4.
5. Qin J, Li R, Raes J, et al. A human gut microbi al gene catalogue established by metagenomic sequencing. Nature 2010; 464 : 59-65.
6. Schloissnig S, Arumugam M, Sunagawa S, et al. G enomic variation landscape of the human gut microbiome. Nature 2013; 493 : 45-50.
7. Maurice CF, Haiser HJ, Turnbaugh PJ. Xenobiotic s shape the physiology and gene expression of the active human gut microbiome. Cell 2013; 152 : 39-50.
8. Kamada N, Seo SU, Chen GY, Nunez G. Role of the gut microbiota in immunity and inflammatory disease. Nat Rev Immunol 2013; 13 : 321-35.
9. Atarashi K, Tanoue T, Shima T, et al. Induction of colonic regulatory T cells by indigenous Clostridium species. Science 2011; 331 : 337-41.
10. Bloom SM, Bijanki VN, Nava GM, et al. Commensa l Bacteroides species induce colitis in host-genotypespecific fashion in a mouse model of inflammatory bowel disease. Cell Host Microbe 2011; 9 : 390-403.
11. Round JL, Lee SM, Li J, et al. The Toll-like r eceptor 2 pathway establishes colonization by a commensal of the human microbiota. Science 2011 ; 332 : 974-7.
12. Hooper LV, Littman DR, Macpherson AJ. Interact ions between the microbiota and the immune system. Science 2012; 336 : 1268-73.
13. Smith MI, Yatsunenko T, Manary MJ, et al. Gut microbiomes of Malawian twin pairs discordant for kwashiorkor. Science 2013 ; 339 : 548-54.
14. Markle JG, Frank DN, Mortin-Toth S, et al. Sex differences in the gut microbiome drive hormonedependent regulation of autoimmunity. Science 2013 ; 339 : 1084-8.
15. Qin J, Li Y, Cai Z, et al. A metagenome-wide a ssociation study of gut microbiota in type 2 diabetes. Nature 2012 ; 490 : 55-60.
16. Manichanh C, Borruel N, Casellas F, Guarner F. The gut microbiota in IBD. Nat Rev Gastroenterol Hepatol 2012; 9 : 599-608.
17. Khan KJ, Ullman TA, Ford AC, et al. Antibiotic therapy in inflammatory bowel disease: a systematic review and meta-analysis. Am J Gastroenterol 2011 ; 106 : 661-73.
18. Rutter MD, Saunders BP, Wilkinson KH, et al. T hirtyyear analysis of a colonoscopic surveillance program for neoplasia in ulcerative colitis. Gastroenterology 2006 ; 130 : 1030-8.
19. Blaser MJ, Falkow S. What are the consequences of the disappearing human microbiota? Nat Rev Microbiol 2009; 7 : 887-94.
20. Sokol H, Pigneur B, Watterlot L, et al. Faecal ibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients. Proc Natl Acad Sci USA 2008; 105 : 16731-6.
21. Swidsinski A, Ladhoff A, Pernthaler A, et al. Mucosal flora in inflammatory bowel disease. Gastroenterology 2002 ; 122 : 44-54.
22. Joossens M, Huys G, Cnockaert M, et al. Dysbio sis of the faecal microbiota in patients with Crohn's disease and their unaffected relatives. Gut 2011 ; 60 : 631-7.
23. Rehman A, Sina C, Gavrilova O, et al. Nod2 is essential for temporal development of intestinal microbial communities. Gut 2011 ; 60 : 1354-62.
24. Couturier-Maillard A, Secher T, Rehman A, et a l. NOD2-mediated dysbiosis predisposes mice to transmissible colitis and colorectal cancer. J Clin Invest 2013; 123 : 700-11.
25. Arthur JC, Perez-Chanona E, Muhlbauer M, et al. Intestinal inflammation targets cancer-inducing activity of the microbiota. Science 2012 ; 338 : 120-3.
26. Jobin C. Microbiome : un nouveau facteur de risque de cancer colorectal ? Med Sci (Paris) 2013; 29 : 582-5.