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Volumn 94, Issue 2, 2013, Pages 185-187

CYP2D6 genotype and tamoxifen activity: Understanding interstudy variability in methodological quality

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 2D6; DEXTROMETHORPHAN; DIPHENHYDRAMINE; ENDOXIFEN; TAMOXIFEN;

EID: 84880758064     PISSN: 00099236     EISSN: 15326535     Source Type: Journal    
DOI: 10.1038/clpt.2013.66     Document Type: Review
Times cited : (42)

References (10)
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    • Association between CYP2D6 polymorphisms and outcomes among women with early stage breast cancer treated with tamoxifen
    • Schroth, W. et al. Association between CYP2D6 polymorphisms and outcomes among women with early stage breast cancer treated with tamoxifen. JAMA 302, 1429-1436 (2009).
    • (2009) JAMA , vol.302 , pp. 1429-1436
    • Schroth, W.1
  • 2
    • 84872587241 scopus 로고    scopus 로고
    • Tamoxifen use in postmenopausal breast cancer: CYP2D6 matters
    • Brauch, H. et al. Tamoxifen use in postmenopausal breast cancer: CYP2D6 matters. J. Clin. Oncol. 31, 176-180 (2013).
    • (2013) J. Clin. Oncol , vol.31 , pp. 176-180
    • Brauch, H.1
  • 3
    • 80052020634 scopus 로고    scopus 로고
    • Genotype-guided tamoxifen dosing increases active metabolite exposure in women with reduced CYP2D6 metabolism: A multicenter study
    • Irvin, W.J., Jr et al. Genotype-guided tamoxifen dosing increases active metabolite exposure in women with reduced CYP2D6 metabolism: a multicenter study. J. Clin. Oncol. 29, 3232-3239 (2011).
    • (2011) J. Clin. Oncol , vol.29 , pp. 3232-3239
    • Irvin Jr., W.J.1
  • 4
    • 80052009180 scopus 로고    scopus 로고
    • Dextromethorphan as a phenotyping test to predict endoxifen exposure in patients on tamoxifen treatment
    • de Graan, A.J. et al. Dextromethorphan as a phenotyping test to predict endoxifen exposure in patients on tamoxifen treatment. J. Clin. Oncol. 29, 3240-3246 (2011).
    • (2011) J. Clin. Oncol , vol.29 , pp. 3240-3246
    • De Graan, A.J.1
  • 5
    • 79955485361 scopus 로고    scopus 로고
    • Tamoxifen metabolite concentrations, CYP2D6 genotype, and breast cancer outcomes
    • Madlensky, L. et al. Tamoxifen metabolite concentrations, CYP2D6 genotype, and breast cancer outcomes. Clin. Pharmacol. Ther. 89, 718-725 (2011).
    • (2011) Clin. Pharmacol. Ther , vol.89 , pp. 718-725
    • Madlensky, L.1
  • 6
    • 78650890739 scopus 로고    scopus 로고
    • CYP2D6 gene variants: Association with breast cancer specific survival in a cohort of breast cancer patients from the United Kingdom treated with adjuvant tamoxifen
    • Abraham, J.E. et al. CYP2D6 gene variants: association with breast cancer specific survival in a cohort of breast cancer patients from the United Kingdom treated with adjuvant tamoxifen. Breast Cancer Res. 12, R64 (2010).
    • (2010) Breast Cancer Res , vol.12
    • Abraham, J.E.1
  • 7
    • 77956242845 scopus 로고    scopus 로고
    • CYP2D6 polymorphisms as predictors of outcome in breast cancer patients treated with tamoxifen: Expanded polymorphism coverage improves risk stratification
    • Schroth, W. et al. CYP2D6 polymorphisms as predictors of outcome in breast cancer patients treated with tamoxifen: expanded polymorphism coverage improves risk stratification. Clin. Cancer Res. 16, 4468-4477 (2010).
    • (2010) Clin. Cancer Res , vol.16 , pp. 4468-4477
    • Schroth, W.1
  • 8
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    • Laboratory testing of CYP2D6 alleles in relation to tamoxifen therapy
    • Lyon, E. et al. Laboratory testing of CYP2D6 alleles in relation to tamoxifen therapy. Genet. Med. 14, 990-1000 (2012).
    • (2012) Genet. Med , vol.14 , pp. 990-1000
    • Lyon, E.1
  • 9
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    • Lessons for pharmacogenomics studies: Association study between CYP2D6 genotype and tamoxifen response
    • Kiyotani, K. et al. Lessons for pharmacogenomics studies: association study between CYP2D6 genotype and tamoxifen response. Pharmacogenet. Genomics 20, 565-568 (2010).
    • (2010) Pharmacogenet. Genomics , vol.20 , pp. 565-568
    • Kiyotani, K.1
  • 10
    • 80053545173 scopus 로고    scopus 로고
    • Pharmacogenetic testing affects choice of therapy among women considering tamoxifen treatment
    • Lorizio, W. et al. Pharmacogenetic testing affects choice of therapy among women considering tamoxifen treatment. Genome Med. 3, 64 (2011).
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    • Lorizio, W.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.