Decreased Expression of AZGP1 Is Associated with Poor Prognosis in Primary Gastric Cancer

PLoS ONE

Volumn 8, Issue 7, 2013, Pages

  Huang, Chun yu ^a   Zhao, Jing jing ^a   Lv, Lin ^a   Chen, Yi bing ^a   Li, Yuan fang ^a   Jiang, Shan shan ^a   Wang, Wei ^a   Pan, Ke ^a   Zheng, Yan ^a   Zhao, Bai wei ^a   Wang, Dan dan ^a   Chen, Yong ming ^a   Yang, Lei ^a   Zhou, Zhi wei ^a   Xia, Jian chuan ^a  

^a SUN YAT SEN UNIVERSITY CANCER CENTER   (China)

Author keywords

[No Author keywords available]

Indexed keywords

2 ZINC GLYCOPROTEIN 1; GLYCOPROTEIN; MESSENGER RNA; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CANCER GRADING; CANCER PATIENT; CANCER STAGING; CANCER SURVIVAL; CONTROLLED STUDY; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; METASTASIS POTENTIAL; OVERALL SURVIVAL; PRIMARY TUMOR; PROGNOSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SEX DIFFERENCE; STOMACH ADENOCARCINOMA; STOMACH CANCER; SURVIVAL TIME; TUMOR INVASION; TUMOR LOCALIZATION; WESTERN BLOTTING;

BLOTTING, WESTERN; CARRIER PROTEINS; GENE EXPRESSION REGULATION, NEOPLASTIC; GLYCOPROTEINS; HUMANS; IMMUNOHISTOCHEMISTRY; KAPLAN-MEIER ESTIMATE; MULTIVARIATE ANALYSIS; PROGNOSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; STOMACH NEOPLASMS;

EID: 84880744990     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0069155     Document Type: Article

References (32)

1. Jemal A, Bray F, (2011) Center MM, Ferlay J, Ward E, et al (2011) Global cancer statistics. CA Cancer J Clin 61: 69-90.
2. Ferlay J, Shin HR, Bray F, Forman D, Mathers C, et al. (2010) Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer 127: 2893-2917.
3. Yang L, (2006) Incidence and mortality of gastric cancer in China. World J Gastroenterol 12: 17-20.
4. Macdonald JS, Smalley SR, Benedetti J, Hundahl SA, Estes NC, et al. (2001) Chemoradiotherapy after surgery compared with surgery alone for adenocarcinoma of the stomach or gastroesophageal junction. N Engl J Med 345: 725-730.
5. Burgi W, Schmid K, (1961) Preparation and properties of Zn-alpha 2-glycoprotein of normal human plasma. J Biol Chem 236: 1066-1074.
6. Ueyama H, Niwa M, Tada T, Sasaki M, Ohkubo I, (1991) Cloning and nucleotide sequence of a human Zn-alpha 2-glycoprotein cDNA and chromosomal assignment of its gene. Biochem Biophys Res Commun 177: 696-703.
7. Ueyama H, Deng HX, Ohkubo I, (1993) Molecular cloning and chromosomal assignment of the gene for human Zn-alpha 2-glycoprotein. Biochemistry 32: 12968-12976.
8. Tada T, Ohkubo I, Niwa M, Sasaki M, Tateyama H, et al. (1991) Immunohistochemical localization of Zn-alpha 2-glycoprotein in normal human tissues. J Histochem Cytochem 39: 1221-1226.
9. Frenette G, Dube JY, Lazure C, Paradis G, Chretien M, et al. (1987) The major 40-kDa glycoprotein in human prostatic fluid is identical to Zn-alpha 2-glycoprotein. Prostate 11: 257-270.
10. Sanchez LM, Lopez-Otin C, Bjorkman PJ, (1997) Biochemical characterization and crystalization of human Zn-alpha2-glycoprotein, a soluble class I major histocompatibility complex homolog. Proc Natl Acad Sci U S A 94: 4626-4630.
11. Ohkubo I, Niwa M, Takashima A, Nishikimi N, Gasa S, et al. (1990) Human seminal plasma Zn-alpha 2-glycoprotein: its purification and properties as compared with human plasma Zn-alpha 2-glycoprotein. Biochim Biophys Acta 1034: 152-156.
12. Araki T, Gejyo F, Takagaki K, Haupt H, Schwick HG, et al. (1988) Complete amino acid sequence of human plasma Zn-alpha 2-glycoprotein and its homology to histocompatibility antigens. Proc Natl Acad Sci U S A 85: 679-683.
13. Hirai K, Hussey HJ, Barber MD, Price SA, Tisdale MJ, (1998) Biological evaluation of a lipid-mobilizing factor isolated from the urine of cancer patients. Cancer Res 58: 2359-2365.
14. Russell ST, Zimmerman TP, Domin BA, Tisdale MJ, (2004) Induction of lipolysis in vitro and loss of body fat in vivo by zinc-alpha2-glycoprotein. Biochim Biophys Acta 1636: 59-68.
15. Bao Y, Bing C, Hunter L, Jenkins JR, Wabitsch M, et al. (2005) Zinc-alpha2-glycoprotein, a lipid mobilizing factor, is expressed and secreted by human (SGBS) adipocytes. FEBS Lett 579: 41-47.
16. Bing C, Bao Y, Jenkins J, Sanders P, Manieri M, et al. (2004) Zinc-alpha2-glycoprotein, a lipid mobilizing factor, is expressed in adipocytes and is up-regulated in mice with cancer cachexia. Proc Natl Acad Sci U S A 101: 2500-2505.
17. Diez-Itza I, Sanchez LM, Allende MT, Vizoso F, Ruibal A, et al. (1993) Zn-alpha 2-glycoprotein levels in breast cancer cytosols and correlation with clinical, histological and biochemical parameters. Eur J Cancer 29A: 1256-1260.
18. Freije JP, Fueyo A, Uria J, Lopez-Otin C, (1991) Human Zn-alpha 2-glycoprotein cDNA cloning and expression analysis in benign and malignant breast tissues. FEBS Lett 290: 247-249.
19. Hale LP, Price DT, Sanchez LM, Demark-Wahnefried W, Madden JF, (2001) Zinc alpha-2-glycoprotein is expressed by malignant prostatic epithelium and may serve as a potential serum marker for prostate cancer. Clin Cancer Res 7: 846-853.
20. Kong B, Michalski CW, Hong X, Valkovskaya N, Rieder S, et al. (2010) AZGP1 is a tumor suppressor in pancreatic cancer inducing mesenchymal-to-epithelial transdifferentiation by inhibiting TGF-beta-mediated ERK signaling. Oncogene 29: 5146-5158.
21. Hartgrink HH, Jansen EP, van Grieken NC, van de Velde CJ, (2009) Gastric cancer. Lancet 374: 477-490.
22. Tabin CJ, Bradley SM, Bargmann CI, Weinberg RA, Papageorge AG, et al. (1982) Mechanism of activation of a human oncogene. Nature 300: 143-149.
23. Weinberg RA, (1991) Tumor suppressor genes. Science 254: 1138-1146.
24. Vogelstein B, Kinzler KW, (2004) Cancer genes and the pathways they control. Nat Med 10: 789-799.
25. Descazeaud A, de la Taille A, Allory Y, Faucon H, Salomon L, et al. (2006) Characterization of ZAG protein expression in prostate cancer using a semi-automated microscope system. Prostate 66: 1037-1043.
26. Brysk MM, Lei G, Adler-Storthz K, Chen Z, Brysk H, et al. (1999) Zinc-alpha2-glycoprotein expression as a marker of differentiation in human oral tumors. Cancer Lett 137: 117-120.
27. Gagnon S, Tetu B, Dube JY, Tremblay RR, (1990) Expression of Zn-alpha 2-glycoprotein and PSP-94 in prostatic adenocarcinoma. An immunohistochemical study of 88 cases. Am J Pathol 136: 1147-1152.
28. Zhang XF, Huang CM, Lu HS, Wu XY, Wang C, et al. (2004) Surgical treatment and prognosis of gastric cancer in 2,613 patients. World J Gastroenterol 10: 3405-3408.
29. Irmak S, Tilki D, Heukeshoven J, Oliveira-Ferrer L, Friedrich M, et al. (2005) Stage-dependent increase of orosomucoid and zinc-alpha2-glycoprotein in urinary bladder cancer. Proteomics 5: 4296-4304.
30. Zorin NA, Zorina VN, Zorina RM, (2006) [Role of proteins of the macroglobulin family in regulation of tumor growth]. Ontogenez 37: 12-19.
31. Zorin NA, Zorina VN, Zorina RM, (2006) [The role of macroglobulin family proteins in the regulation of inflammation]. Biomed Khim 52: 229-238.
32. He N, Brysk H, Tyring SK, Ohkubo I, Brysk MM (2001) Zinc-alpha(2)-glycoprotein hinders cell proliferation and reduces cdc2 expression. J Cell Biochem Suppl Suppl 36: 162-169.