Increased radial glia quiescence, decreased reactivation upon injury and unaltered neuroblast behavior underlie decreased neurogenesis in the aging zebrafish telencephalon

Journal of Comparative Neurology

Volumn 521, Issue 13, 2013, Pages 3099-3115

  Edelmann, Kathrin ^a   Glashauser, Lena ^a   Sprungala, Susanne ^a,c   Hesl, Birgit ^a   Fritschle, Maike ^a   Ninkovic, Jovica ^a   Godinho, Leanne ^b   Chapouton, Prisca ^a  

^a INSTITUTE OF EPIDEMIOLOGY   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^c JAMES COOK UNIVERSITY   (Australia)

Author keywords

Adult neurogenesis; Aging; DeltaA; Gfap; Injury; Neural stem cells; Quiescence; Radial glia; Regeneration; S100 ; Telencephalon; Zebrafish

Indexed keywords

AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL COUNT; CELL CYCLE; CELL FATE; CELL POPULATION; CELL REGENERATION; CONTROLLED STUDY; EMBRYO; GLIA; NERVE CELL MEMBRANE POTENTIAL; NERVOUS SYSTEM DEVELOPMENT; NEURAL STEM CELL; NEUROBLAST; NONHUMAN; OLFACTORY BULB; PRIORITY JOURNAL; PROGENY; STEADY STATE; TELENCEPHALON; TRAUMATIC BRAIN INJURY; VENTRICULAR ZONE; ZEBRA FISH;

ADULT NEUROGENESIS; AGING; DELTAA; GFAP; INJURY; NEURAL STEM CELLS; QUIESCENCE; RADIAL GLIA; REGENERATION; S100Β; TELENCEPHALON; ZEBRAFISH;

AGE FACTORS; AGING; ANIMALS; ANIMALS, GENETICALLY MODIFIED; BRAIN INJURIES; BROMODEOXYURIDINE; CELL COUNT; DISEASE MODELS, ANIMAL; GREEN FLUORESCENT PROTEINS; HISTONES; HU PARANEOPLASTIC ENCEPHALOMYELITIS ANTIGENS; NERVE REGENERATION; NERVE TISSUE PROTEINS; NEURAL STEM CELLS; NEUROGLIA; PROLIFERATING CELL NUCLEAR ANTIGEN; S100 CALCIUM BINDING PROTEIN BETA SUBUNIT; TELENCEPHALON; ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 84880646091     PISSN: 00219967     EISSN: 10969861     Source Type: Journal    
DOI: 10.1002/cne.23347     Document Type: Article

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