Phase II study evaluating lapatinib in combination with nab-paclitaxel in HER2-overexpressing metastatic breast cancer patients who have received no more than one prior chemotherapeutic regimen

Breast Cancer Research and Treatment

Volumn 137, Issue 2, 2013, Pages 457-464

  Yardley, Denise A ^a,b   Hart, Lowell ^c   Bosserman, Linda ^d   Salleh, Mansoor N ^e   Waterhouse, David M ^f   Hagan, Maura K ^g   Richards, Paul ^h   Desilvio, Michelle L ⁱ   Mahoney, Janine M ⁱ   Nagarwala, Yasir ⁱ  

^a SARAH CANNON RESEARCH INSTITUTE   (United States)

^b PLLC   (United States)

^c Florida Cancer Specialists   (United States)

^d Willshire Oncology Medical Group   (United States)

^e Georgia Cancer Specialists   (United States)

^f Oncology Hematology Care   (United States)

^g Virginia Cancer Care   (United States)

^h Oncology and Hematology Associ of SW ^*  (United States)

ⁱ GLAXOSMITHKLINE   (United States)

Author keywords

Breast cancer; HER2; Lapatinib; Nab paclitaxel

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 2; LAPATINIB; PACLITAXEL; 130 NM ALBUMIN BOUND PACLITAXEL; 130-NM ALBUMIN-BOUND PACLITAXEL; ALBUMINOID; ANTINEOPLASTIC AGENT; ERBB2 PROTEIN, HUMAN; QUINAZOLINE DERIVATIVE;

ADULT; AGED; ALOPECIA; ANEMIA; ARTICLE; BREAST CANCER; BREAST METASTASIS; CANCER COMBINATION CHEMOTHERAPY; CANCER GROWTH; CONSTIPATION; CONTINUOUS INFUSION; CONTROLLED STUDY; COUGHING; DECREASED APPETITE; DEHYDRATION; DIARRHEA; DOSE RESPONSE; DRUG EFFICACY; DRUG RESPONSE; DRUG SAFETY; DRUG WITHDRAWAL; DYSGEUSIA; DYSPEPSIA; DYSPNEA; EPISTAXIS; FATIGUE; FEASIBILITY STUDY; FEBRILE NEUTROPENIA; FEVER; HUMAN; HYPOKALEMIA; INSOMNIA; MAJOR CLINICAL STUDY; METASTASIS; MULTICENTER STUDY; MULTIPLE CYCLE TREATMENT; NAIL DISEASE; NAUSEA; NEUTROPENIA; PAIN; PERIPHERAL EDEMA; PERIPHERAL NEUROPATHY; PHASE 2 CLINICAL TRIAL; PRIORITY JOURNAL; PROGRESSION FREE SURVIVAL; PROTEIN EXPRESSION; RASH; SIDE EFFECT; VOMITING; WEIGHT REDUCTION; BREAST TUMOR; CHEMICALLY INDUCED DISORDER; DISEASE FREE SURVIVAL; FEMALE; METABOLISM; MIDDLE AGED; MORTALITY; PATHOLOGY; TREATMENT OUTCOME; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; ALBUMINS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BREAST NEOPLASMS; DIARRHEA; DISEASE-FREE SURVIVAL; FEMALE; HUMANS; MIDDLE AGED; NAUSEA; PACLITAXEL; QUINAZOLINES; RECEPTOR, ERBB-2; TREATMENT OUTCOME;

MLCS; MLOWN;

EID: 84880642370     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-012-2341-9     Document Type: Article

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